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Genetic differences may influence joint pain among women taking lifesaving breast cancer drugs
Date:6/1/2010

being married. Patients who stopped AI treatment early cited side effects as the main reason, with arthralgia being the most common complaint. Effects on bone, hot flashes and cognitive effects were also named as reasons for cessation of therapy.

"These data suggest that we can develop a profile of the women who are most likely to make the decision to terminate their AI therapy prematurely, and if we can do that, we can design better supportive interventions for these women and incorporate them into our clinical practice," DeMichele says. "This information, derived directly from the patients themselves, reinforces our understanding that assessing and managing the side effects of cancer therapy, including joint pain, is critical to the overall success we can achieve in managing the disease itself."

Mao's study will be presented at a poster session on Breast Cancer from 2 p.m. to 6 p.m. on Monday, June 7. Stricker will present the premature discontinuation of AI findings at a poster session on Health Service Research from 1 p.m. to 5 p.m. on the 7th. Claire Friedman will present the functional disability findings at a poster session on Patient and Survivor Care from 1 p.m. to 5 p.m. on June 7.

Patients are available to discuss their experience with these treatments, upon request.


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Contact: Kim Guenther
kim.guenther@uphs.upenn.edu
215-200-2312
University of Pennsylvania School of Medicine
Source:Eurekalert

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