PHILADELPHIA - Genetic researchers from the University of Pennsylvania have combined data from existing archaeological and linguistic studies of Africa with human genetic data to shed light on the demographic history of the continent from which all human activity emerged.
The study reveals not just a clearer picture of the continent's history but also the importance of having independent lines of evidence in the interpretation of genetic and genomic data in the reconstruction of population histories.
The study is published in the current issue of the Proceedings of the National Academy of Sciences.
The results, according to Penn geneticist Sarah Tishkoff, a Penn Integrates Knowledge professor with joint appointments in the schools of Medicine and Arts and Science, is that genetic variation in Africa is structured geographically, and to a lesser extent, linguistically. The findings are consistent with the notion that populations in close geographic proximity that speak linguistically similar languages are more likely to exchange genes.
Furthermore, genetic variation in Africa appears consistent with the natural, geographic barriers that limit gene flow. In particular, there are geographic, and therefore genetic, distinctions between northern African and sub-Saharan African populations due to the vast desert that limited migration.
"Focusing on particular exceptions to these broad patterns will enable us to discern and fully appreciate the complex population histories that have contributed to extant patterns of genetic variation," said Tishkoff, the David and Lyn Silfen University Associate Professor. "Disentangling past population histories is a formidably complicated task that benefits from the synthesis of archaeological, linguistic and genetic data."
With this three-pronged approach, a clearer picture emerges.
Archaeology provides insights into ancient technology and culture, affordi
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| Contact: Jordan Reese jreese@upenn.edu 215-573-6604 University of Pennsylvania Source:Eurekalert |