Navigation Links
Genetic Variants Tied to Obesity
Date:12/15/2008

Findings add to knowledge about appetite regulation among people

MONDAY, Dec. 15 (HealthDay News) -- Certain people just may be destined to be obese, based on the discovery of six additional genetic variants tied to people with higher body mass index, a new study says.

The study by an international consortium, published online Dec. 14 in Nature Genetics, adds to previous research that linked two other genetic variants to obesity.

"One of the interesting things is that the genes near these variants are all active in the central nervous system, suggesting that inherited variation in appetite regulation may have something to do with people's predisposition to obesity," study leader Dr. Joel Hirschhorn of Children's Hospital Boston and the Broad Institute of Harvard and MIT, said in a news release issued by some of the consortium participants.

The study, by the Genetic Investigation of Anthropometric Traits (GIANT) consortium, concluded that each individual known variant had a small but cumulative effect on a person's BMI, a ratio of weight to height. In all, it added up to an average of 10 pounds in those with most of the variants, compared to those with the fewest. However, Hirschhorn said the researchers may have found only a handful of possibly hundreds of genetic regions that made such small contributions to one's weight, and more studies would be needed to uncover them all.

"As we learn more about what some of the genes in these regions do, we hope that these discoveries might suggest routes to new therapies for obesity," joint first author of the study, Dr. Elizabeth Speliotes of Massachusetts General Hospital, said in the news release.

Previous studies in families or twins have found that genetics account for up to 70 percent of BMI variation in the general population.

The World Health Association estimates that more than 1 billion adults worldwide are overweight, with at least 300 million of them classified as obese (having a BMI of 30 or above).

More information

The American Heart Association has more about body mass index.



-- Kevin McKeever



SOURCE: Children's Hospital Boston, Broad Institute of Harvard and Massachusetts Institute of Technology, Massachusetts General Hospital, news release, Dec. 14, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Genetic Link Between Type 1 Diabetes, Celiac Disease Seen
2. Genetic Markers Identified for Alcohol Response in UCSF Gallo Study
3. PTSD Risk Rooted in Stress and Genetics
4. New technique enables faster genetic diagnosis for hereditary diseases
5. Texas and North Carolina Students Tackle Lifesaving Research in Chemistry and Genetics, Taking Home the Grand Prize at Nations Premier High School Science Competition
6. The SCOOTER Store Donates Power Wheelchair to Texas Teenager With Rare Genetic Disorders
7. Few Ontario women with invasive ovarian cancer referred for genetic testing of breast cancer genes
8. Novel bioreactor enhances interleukin-12 production in genetically-modified tobacco plants
9. Genetic breakdown in Fanconi anemia may have link to HPV-associated cancer
10. Understanding donor-recipient genetics could decrease early kidney transplant complications
11. Do You Have Genetic COPD?
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/21/2017)... ... April 21, 2017 , ... Airway ... new partnership with the highly regarded and well renowned Asian distributor, Discovery Sleep. ... & myTAP PAP Nasal Pillow Mask, and will stabilize and strengthen Airway’s presence ...
(Date:4/21/2017)... ... April 21, 2017 , ... ... imaging practices, is seeking candidates to serve on its Accreditation and Standards ... , “RadSite’s ultimate mission is improving image quality and reducing patient radiation ...
(Date:4/21/2017)... CA (PRWEB) , ... April 21, 2017 , ... ... to experienced, personalized dental care since 1985. After thirty-two years, Dr. Latner has become ... privilege to help my numerous clients over the years with all their dental needs,” ...
(Date:4/21/2017)... ... ... During April 21-23, Super-Sod will join the vendor market of the Sacred Heart ... from the avid gardener to the landscape admirer — during the three-day schedule. , ... grand venue, and we are certainly looking forward to participating in this year’s festival,” ...
(Date:4/21/2017)... (PRWEB) , ... April 21, 2017 , ... ... Service Provider, announces a significant bandwidth upgrade infrastructure service to Tele-Media Solutions. ... Solutions. One of IFN’s consortium member-owners, Tele-Media Solution’s protect transport with 3GB ...
Breaking Medicine News(10 mins):
(Date:4/20/2017)... , April 20, 2017  Cogentix Medical, ... focused on providing the Urology, Uro/Gyn and Gynecology ... that Ash Keswani has joined the Company as ... this newly created position, Mr. Keswani will report ... CEO. "Our organization is delighted that ...
(Date:4/20/2017)... April 20, 2017 Research and Markets has ... Innovation Driven by Rapidly Expanding Injectables Market and Increasing Usage of ... ... delivery technologies will rise from USD 20 Billion in 2015 to ... Drug Delivery Technologies - Innovation Driven by Rapidly Expanding Injectables Market ...
(Date:4/20/2017)... 2017 Eyevensys, a private biotechnology ... gene expression technology that enables the safe, local, sustained ... a wide range of ophthalmic diseases, announces it has ... Regulatory Agency (MHRA) to advance its technology into clinical ... The ...
Breaking Medicine Technology: