Navigation Links
Genetic Trait Could Predict Lung Cancer
Date:11/18/2008

But research is preliminary, scientists stress

TUESDAY, Nov. 18 (HealthDay News) -- Canadian scientists may have discovered a genetic trait that could provide an early indication of which former smokers will develop lung cancer.

The research, reported Tuesday at the American Association for Cancer Research conference in Washington, D.C., is still in the preliminary stages.

Still, "the benefit would hopefully be more targeted treatment," said study author Emily A. Vucic, a graduate student at British Columbia Cancer Research Centre in Vancouver.

While smoking rates continue to shrink, lung cancer remains the second most common cancer in the United States for both genders. According to the American Cancer Society, it trails only breast cancer (in women) and prostate cancer (in men).

The society estimates that 161,840 Americans will die this year from lung cancer. An estimated 85 percent to 90 percent of cases across the world are caused by smoking.

In the new study, Vucic and colleagues examined the DNA of eight former smokers who had undergone lung cancer surgery and eight former smokers who had not. The DNA was collected from tissue in their airways.

The researchers looked for signs of damage to the DNA in the cells that make up the tissue. If damage exists, genes in the cell may not be able to prevent the cells from multiplying and turning into cancer cells, Vucic said.

The DNA is "definitely affected by cigarette smoke," she said.

The study found that there were more signs of damage in the former smokers who developed lung cancer. It's possible that a simple mouth swab could provide DNA for testing and give doctors an idea of the lung-cancer prospects for patients, Vucic said.

The scientists now plan to enroll 100 people in a follow-up trial, Vucic said.

In another study to be released at the meeting, researchers reported that cruciferous vegetables can help current and former smokers avoid lung cancer. The vegetables include broccoli, cauliflower, cabbage, Brussels sprouts, collard greens and some Chinese vegetables.

Those who ate the most raw cruciferous vegetables (at least 4.5 servings per month) had a lower risk of lung cancer than those who ate less than 2.5 servings a month. Comparing the two groups after controlling for other factors, the rates were 20 percent to 55 percent lower in the first group, depending on the types of vegetable eaten and the duration and intensity of smoking, said Dr. Li Tang, a researcher at the Roswell Park Cancer Institute in Buffalo.

Other research has linked the vegetables to lower rates of bladder cancer, Tang said. The vegetables appear to produce reactions in the body that help prevent cancer.

"Quitting smoking is the best thing to do to reduce risk, but there are things, like increasing intake of vegetables, that may also reduce your risk," Tang said.

More information

Learn more about lung cancer from the U.S. National Cancer Institute.



SOURCES: Emily A. Vucic, graduate student, British Columbia Cancer Research Centre, Vancouver, B.C.; Li Tang, M.D., Ph.D., researchers, Roswell Park Cancer Institute, Buffalo, N.Y.; Nov. 18, 2008, presentation, American Association for Research's Frontiers in Cancer Prevention Research conference, Washington, D.C.


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Many Parents Share Genetic Test Findings With Kids
2. Genetic predisposition increases childhood asthma risk
3. New Alzheimers findings: High stress and genetic risk factor lead to increased memory decline
4. Test Spots Genetic Damage Done by Smoking
5. Scientists demonstate link between genetic variant and effectiveness of smoking cessation meds
6. Scientists highlight benefits of genetic research in sport, but warn of ethical concerns
7. Genetics Hold Promise, Challenges for Cancer Care
8. Researchers genetically engineer micro-organisms into tiny factories
9. Study Questions Genetic Screening for Treatable Diseases
10. Researchers provide genetic associations from a genome-wide scan for cardiovascular disease traits
11. Genetic variation affects smoking cessation treatment
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Genetic Trait Could Predict Lung Cancer
(Date:12/9/2016)... ... December 09, 2016 , ... Flottman ... and outserts. As a means of expanding capabilities Flottman has added a ... to individually code professional inserts (PIs) and patient package inserts (PPIs) that will ...
(Date:12/9/2016)... , ... December 09, 2016 , ... An inventor from ... to safely ride all types of amusement park rides. , The patent-pending SAFETY STRAP ... is easy to use and could be set up in a matter of minutes, ...
(Date:12/9/2016)... ... December 09, 2016 , ... "I had a terrible time trying ... Va. "I thought that if the nebulizer had a more child-friendly design, then children ... , He developed the patent-pending NEBY to avoid the need to deliver medication via ...
(Date:12/8/2016)... MA (PRWEB) , ... December 08, 2016 , ... ... Workers Compensation Research Institute (WCRI) officially opened registration today for its 33rd ... Hotel in Boston, MA . , The theme of the conference is “Persistent ...
(Date:12/8/2016)... , ... December 08, 2016 , ... ... offering Medication Therapy Management (MTM), adherence, and other pharmacist-delivered patient care services, has ... general counsel and Eric Hoessel to vice president of sales. , Litsinger ...
Breaking Medicine News(10 mins):
(Date:12/9/2016)... , Dec 9, 2016 Research ... Screening Market - Forecast to 2021" report to their ... ... of open innovative models in the pharmaceutical and biotechnology industry ... and rising government funding. Emerging markets and growing research activities ...
(Date:12/9/2016)...  RxWiki Inc., a digital health company that powers ... thousands of pharmacies through its Digital Pharmacist SaaS platform, ... "50 on Fire" Award in the Health and Life ... the award as one of Austin,s fastest growing companies," ... RxWiki. "Our platform gives independent retail pharmacies the digital ...
(Date:12/9/2016)... , Dec. 9, 2016  Forge Therapeutics, ... AG (Frankfurt Stock Exchange: EVT, TecDAX, ISIN: DE0005664809) ... ,LpxC, for the treatment of bacterial infections including ... been recognized as an attractive antibacterial target for ... lack of suitable chemical starting points has hampered ...
Breaking Medicine Technology: