Navigation Links
Genetic Test for Heart Disease Risk in the Works
Date:2/8/2009

International studies lay groundwork for designing way to spot susceptible patients

SUNDAY, Feb. 8 (HealthDay News) -- Perhaps five years from now, you might actually hear your doctor casually say, "While we're at it, let's do a blood test to see if your genetic makeup puts you at high risk of having a heart attack."

So says Dr. Sekar Kathiresan, an assistant professor of medicine at Harvard Medical School and director of preventive cardiology at Massachusetts General Hospital. He is the leader of a group that has identified three new genetic variants associated with an increased risk of heart attack.

That finding, which brings the total of such risk-associated variants to nine, is reported in the Feb. 8 online issue of Nature Genetics. The journal highlights a total of five papers from groups around the world looking at the genetics of heart disease.

The study led by Kathiresan, done by a group of six organizations called the Myocardial Infarction Genetics Consortium, is the largest of the five. It compared the genomes of about 3,000 people who had suffered heart attacks relatively early in life -- under 50 in men, under 60 in women -- with those of 3,000 people who hadn't had a heart attack.

It's known that heart disease tends to cluster in families, Kathiresan said, in part because family members tend to share bad habits, such as smoking. The aim of the study was to single out the role of genes in increased familial risk.

"We looked at about 1 million different spots in the genomes, the frequency of the letters in the genomes in cases and controls," Kathiresan said. "The genome-wide study identified nine spots associated with an increased risk of heart attack, six of which had been previously described. We showed that when you combined the information from the nine different spots, the 20 percent of the people who had the most unfavorable profile had a 2.25-fold greater risk of having
'/>"/>

Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. Many Parents Share Genetic Test Findings With Kids
2. Genetic predisposition increases childhood asthma risk
3. New Alzheimers findings: High stress and genetic risk factor lead to increased memory decline
4. Test Spots Genetic Damage Done by Smoking
5. Scientists demonstate link between genetic variant and effectiveness of smoking cessation meds
6. Scientists highlight benefits of genetic research in sport, but warn of ethical concerns
7. Genetics Hold Promise, Challenges for Cancer Care
8. Researchers genetically engineer micro-organisms into tiny factories
9. Study Questions Genetic Screening for Treatable Diseases
10. Researchers provide genetic associations from a genome-wide scan for cardiovascular disease traits
11. Genetic variation affects smoking cessation treatment
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Genetic Test for Heart Disease Risk in the Works
(Date:9/22/2014)... By Amy Norton ... -- Tiny preemies may fare better when newborn intensive care ... time with their infants, a new study finds. Researchers ... were more alert and were less distressed when their NICU ... families. The findings, published online Sept. 22 in the ...
(Date:9/22/2014)... transplant seems futuristic, if not impossible. But with ... Defense, researchers at University of California, San Diego ... of an entire, functional eye a reality. , ... grail for vision restoration," said Jeffrey Goldberg, MD, ... colleagues at University of Pittsburg Medical Center and ...
(Date:9/22/2014)... 22, 2014 An inventor and anesthesiologist ... the problem of side-sleeping. "My lower arm always became ... designed a solution to this problem," she said. "It’s ... to have your arm 'fall asleep.'" , The Sleeping ... her side more comfortably. It avoids pain and restlessness ...
(Date:9/22/2014)... 22, 2014. Kessler researchers have published a pilot ... wellness program in people with multiple sclerosis (MS). ... health, perceived stress, and pain. "Development and ... living with MS: Description and outcomes" was epublished ... International Journal of MS Care (doi: ...
(Date:9/22/2014)... News) -- Scans of young children,s brains might ... finding could potentially allow doctors to identify those ... preliminary research suggests. "Early identification and interventions ... well as most neurodevelopmental disorders," the study,s senior ... child and adolescent psychiatry at University of California, ...
Breaking Medicine News(10 mins):Health News:Newborn ICUs With Private Family Rooms Benefit Preemies: Study 2Health News:Newborn ICUs With Private Family Rooms Benefit Preemies: Study 3Health News:Looking ahead: Whole eye transplant under development 2Health News:Can Brain Scans Help Predict Young Children's Reading Abilities? 2
... authored by two Memorial University faculty members published in ... the Public Library// of// Science (PLoS). Drs. Amin A. ... the paper, entitled, "Prevalence of depression among house holds ... the mental health policy." ,Dr. Muhammad Gadit ...
... allow a pioneering doctor, currently under house arrest in Henan ... award for her work on behalf// of HIV/AIDS patients, it ... had permission to travel," retired professor Gao Yaojie, 79, told ... holding her under house arrest for two weeks. ...
... found supporting evidence to implicate insulin-like growth factor receptor ... ,In a previous research, Terry J. Smith, M.D. and ... immunoglobulins and IGF-1R as a cause of inflammation and ... , The discovery of these mechanisms in ...
... University have developed a novel spraying method for delivering ... a new low-cost and scaleable technique that offers needle-free ... methods. The process could one day provide a better ... related spread of HIV/AIDS in the developing world. ...
... If you are cooking with garlic, crush the pods first ... benefits and medicinal properties are well known. It has long ... folklore for preventing everything from the common cold and flu ... herbal medicine and it contains compounds shown to help prevent ...
... on Friday plan to distribute 250,000 city-branded condoms as ... the spread of HIV// and other sexually transmitted infections, ... purple and yellow package is printed in English and ... Coming together to stop HIV in D.C.' The first ...
Cached Medicine News:Health News:A Single Biological Mechanism Behind Several Autoimmune Disorders 2Health News:Scientists Partner to Develop and Distribute New Tuberculosis Vaccine 2Health News:Free Condoms Distribution to Prevent HIV in Washington 2
(Date:9/22/2014)... CHICAGO, Ill. , Sept. 22, 2014 /PRNewswire/ ... data from several clinical studies evaluating potential new ... presented at the upcoming 2014 European Society of ... Madrid, Spain . Data being ... evaluating the safety and efficacy of veliparib (ABT-888), ...
(Date:9/22/2014)... DIEGO , Sept. 22, 2014 Arena Pharmaceuticals, ... company is scheduled to present a corporate overview and ... on Friday, September 26, 2014, at 11:30 a.m. Eastern ... Hotel in New York City . ... will be available under the investor relations section of ...
(Date:9/22/2014)... , September 22, 2014 ... Line Development Market by Product (Equipment, Media and Reagents), ... Engineering & Regenerative medicine, Toxicity Testing, Research, Drug ... published by MarketsandMarkets, analyzes and studies the major ... Browse 114 market data tables and 64 ...
Breaking Medicine Technology:AbbVie to Present Clinical Study Data on Potential New Oncology Medicines at the 2014 European Society of Medical Oncology Annual Meeting 2AbbVie to Present Clinical Study Data on Potential New Oncology Medicines at the 2014 European Society of Medical Oncology Annual Meeting 3AbbVie to Present Clinical Study Data on Potential New Oncology Medicines at the 2014 European Society of Medical Oncology Annual Meeting 4Arena Pharmaceuticals to Present at the NewsMakers in the Biotech Industry Conference 2Arena Pharmaceuticals to Present at the NewsMakers in the Biotech Industry Conference 3Cell Line Development Market Worth $3.96 Billion by 2019 2Cell Line Development Market Worth $3.96 Billion by 2019 3Cell Line Development Market Worth $3.96 Billion by 2019 4
... PARSIPPANY, N.J., Jan. 31, 2011 PDI, Inc. (Nasdaq: ... officer, is scheduled to present at the UBS 21st Annual Global ... at the Grand Hyatt New York. The live ... company,s website at http://www.pdi-inc.com . The webcast will be archived ...
... Calif., Jan. 31, 2011 OXIS International, Inc., (OTC ... today announced highly favorable final results from an initial ... patent-pending ERGOFLEX™ joint health formula, launched commercially ... of pain was statistically significant after as little as ...
Cached Medicine Technology:Final Results from ERGOFLEX Study Show Statistically Significant Reduction in Joint Pain in as Little as One Week 2Final Results from ERGOFLEX Study Show Statistically Significant Reduction in Joint Pain in as Little as One Week 3Final Results from ERGOFLEX Study Show Statistically Significant Reduction in Joint Pain in as Little as One Week 4
... combined with a stimulation lead ... Temporary Pacemaker can be used ... pacing is indicated. The device ... as well as diagnostic purposes ...
... Temporary, Transvenous Pacing Lead System Features an ... lubricated guide catheter. The system is designed ... The system is disposable, for temporary single ... of 7 days or less. The lead ...
... system provides an ideal solution for ... laboratory, satellite lab and the clinic ... method with wedge-smear technology, the ADVIA ... in a safe enclosed environment. The ...
It is a cardio-pulmonary exercise testing device....
Medicine Products: