Navigation Links
Genetic Test Shows Promise in Guiding Breast Cancer Care
Date:5/10/2011

By Amanda Gardner
HealthDay Reporter

TUESDAY, May 10 (HealthDay News) -- Scientists have developed a new, albeit preliminary, genetic test that seems to predict which breast cancer patients can benefit from specific types of chemotherapy.

That, in turn, could greatly help guide treatment, according to a study in the May 11 issue of the Journal of the American Medical Association.

The findings are exciting but need to be replicated, said one expert, Dr. Iuliana Shapira, director of cancer genetics at Monter Cancer Center and assistant professor of medicine at Hofstra University North Shore Long Island Jewish Health System in Lake Success, NY. She was not involved in the study.

According to the study's lead author, Dr. W. Fraser Symmans, gene-based tests such as the Oncotype DX are already in wide used to help guide breast cancer care. That test can help predict a patient's chance for breast cancer recurrence, but only if they have estrogen-receptor-positive breast tumor and are treated with hormone therapy, said Symmans, who is professor of pathology at the University of Texas MD Anderson Cancer Center in Houston.

Based on the results of Oncotype DX, "patients with low risk might [be able to] avoid chemotherapy," he said.

The new study looked at a newer "genomic predictor" of breast cancer treatment response and survival for women with newly diagnosed, invasive breast cancer. The study was based on tumor samples taken from 310 patients with HER2/neu-negative breast cancer who were treated sequentially with two chemotherapy drugs, taxane and anthracyline, both common components of breast cancer chemotherapy.

If the tumors were estrogen-receptor (ER)-positive (meaning their tumors responded to estrogen), the women were also treated with hormonal (endocrine) therapy.

The new test appeared to be effective in predicting outcomes: 92 percent of the women that the test predicted would
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. Genetic information may help predict likelihood of survival following chemotherapy for breast cancer
2. Genetic defects hold clues to risk for sudden cardiac death
3. New guidelines for cardiovascular genetic testing
4. Epigenetic study reveals new insights into breast cancer
5. Mayo Clinic finds new genetic cause of neurodegeneration
6. New class of cancer drugs could work in colon cancers with genetic mutation, U-M study finds
7. Liver-cell transplants show promise in reversing genetic disease affecting liver and lungs
8. Hope for children with rare genetic defect
9. Parents Want Genetic Testing for Kids: Study
10. Intellectual disability is frequently caused by non-hereditary genetic problems
11. Study: Parents likely to embrace predictive genetic testing for their children if offered
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Genetic Test Shows Promise in Guiding Breast Cancer Care
(Date:10/1/2014)... 01, 2014 Diet Doc understands that many ... lose weight and their dieting attempts could be easily sabotaged ... hormone diet treatments into their programs as a ... see fast and effective weight loss results, it also allows ... habits to maintain their weight for the future. , Earlier ...
(Date:10/1/2014)... (PRWEB) October 01, 2014 Anti Aging ... and skin rejuvenating destination of choice, is announcing a ... October through to December. , “We’re doing this because ... possible to our top skin clinic in Toronto,” says ... do so much at Anti Aging Clinic, including laser ...
(Date:10/1/2014)... (PRWEB) October 01, 2014 On Sept. ... Chicago-based finalists in the Martha Stewart American Made Awards ... businesses across the country in the fields of crafts, ... be recognized as a finalist in the MSAMAs, which ... products that are improving local communities and changing the ...
(Date:10/1/2014)... Watsonville, California (PRWEB) October 01, 2014 ... initiative to benefit a very special cause. The ... and support for Paws for Veterans, a nonprofit ... veterans, while also rescuing shelter dogs that would ... purchases of featured products will support monthly donations ...
(Date:10/1/2014)... (PRWEB) October 01, 2014 Woodland ... speak to a group of dental specialists who treat ... northern Spain city of Oviedo. Dr. Reshad of the ... lecturer with clients on two continents, will give a ... aesthetic full mouth reconstruction. , “These specialists want to ...
Breaking Medicine News(10 mins):Health News:Diet Doc Announces Their New Version of the Hormone Diet Plan to Target, Attack and Burn Fat Without Dangerous Side Effects 2Health News:Diet Doc Announces Their New Version of the Hormone Diet Plan to Target, Attack and Burn Fat Without Dangerous Side Effects 3Health News:Diet Doc Announces Their New Version of the Hormone Diet Plan to Target, Attack and Burn Fat Without Dangerous Side Effects 4Health News:Anti Aging Clinic, the GTA’s Premier Provider of Anti Aging Treatments, Announces Deal on Units of Botox 2Health News:Chicago Coffee Start-up Makes a Big Impact, Earns National Recognition 2Health News:Nordic Naturals® Inspires Support for Paws for Veterans -- ‘Buy One Bottle. Help Two Heroes.’ Initiative Kicks Off October 1 2Health News:Woodland Hills Dental Implants Expert Training Dental Specialists in Spain Later This Week 2Health News:Woodland Hills Dental Implants Expert Training Dental Specialists in Spain Later This Week 3Health News:Woodland Hills Dental Implants Expert Training Dental Specialists in Spain Later This Week 4
... non-profit, eHealth Initiative applauds President-Elect Obama,s inclusion of ... hospital in the country in his Economic Recovery ... part of his December 6, 2008 Weekly ... , "The effective adoption ...
... National Influenza Vaccination Week (December 8-14); Urges Immunization Throughout the ... SACRAMENTO, Calif., Dec. 8 Health experts recommend annual ... Despite this recommendation, influenza immunization rates fall far short every ... suffer from influenza in an average year. , ...
... they remain disproportionately high for minority women, study finds, , , ... children are developing anemia, according to a new U.S. Centers ... researchers can,t pinpoint reasons for the improvement. , The report ... than half, from 8 percent to less than 4 percent. ...
... Program Continues to Demonstrate Garmin-Slipstream,s Dedication to Anti-Doping and ... BOULDER, Colo., Dec. 8 Slipstream Sports LLC and ... just sporting a new name in 2009, when it ... today announced that it will participate in a new ...
... doses of thiamine vitamin B1 can reverse the ... diabetic nephropathy, develops progressively in patients with type 2 diabetes. ... excretion rate of the protein albumin from the body in ... by Dr Naila Rabbani and Professor Paul J Thornalley at ...
... MATH,SCIENCE & TECHNOLOGY , , ... , Sajith M. Wickramasekara of Raleigh, North ... Grand Prize , , NEW YORK, ... tomorrow bravely took on groundbreaking research of life-threatening infections and deadly ...
Cached Medicine News:Health News:eHealth Initiative Applaudes President-Elect Obama's Recognition of the Importance of Information Technology to Improve U.S. Health Care System 2Health News:Sacramento Mother Dee Dee Abdur-Rahim and Deputy District Attorney Robin Shakely Join the American Lung Association's Faces of Influenza Campaign to Promote Annual Vaccination 2Health News:Sacramento Mother Dee Dee Abdur-Rahim and Deputy District Attorney Robin Shakely Join the American Lung Association's Faces of Influenza Campaign to Promote Annual Vaccination 3Health News:Sacramento Mother Dee Dee Abdur-Rahim and Deputy District Attorney Robin Shakely Join the American Lung Association's Faces of Influenza Campaign to Promote Annual Vaccination 4Health News:Anemia Rates Down for U.S. Women and Children 2Health News:Anemia Rates Down for U.S. Women and Children 3Health News:Top U.S. Professional Cycling Team, Garmin-Slipstream, Partners With ADSI to Continue Anti-Doping Program 2Health News:Top U.S. Professional Cycling Team, Garmin-Slipstream, Partners With ADSI to Continue Anti-Doping Program 3Health News:Vitamin B1 could reverse early-stage kidney disease in diabetes patients 2Health News:Texas and North Carolina Students Tackle Lifesaving Research in Chemistry and Genetics, Taking Home the Grand Prize at Nation's Premier High School Science Competition 2Health News:Texas and North Carolina Students Tackle Lifesaving Research in Chemistry and Genetics, Taking Home the Grand Prize at Nation's Premier High School Science Competition 3Health News:Texas and North Carolina Students Tackle Lifesaving Research in Chemistry and Genetics, Taking Home the Grand Prize at Nation's Premier High School Science Competition 4Health News:Texas and North Carolina Students Tackle Lifesaving Research in Chemistry and Genetics, Taking Home the Grand Prize at Nation's Premier High School Science Competition 5Health News:Texas and North Carolina Students Tackle Lifesaving Research in Chemistry and Genetics, Taking Home the Grand Prize at Nation's Premier High School Science Competition 6Health News:Texas and North Carolina Students Tackle Lifesaving Research in Chemistry and Genetics, Taking Home the Grand Prize at Nation's Premier High School Science Competition 7
(Date:10/1/2014)... , Oct. 1, 2014 Quantum Materials ... volume production of photoactive quantum dots for use ... While offering numerous advantages for solar power generation, ... quantities of quantum dots with which to develop ... them from commercial utilization and acceptance. The company ...
(Date:10/1/2014)... FREMONT, Calif. , Oct. 1, 2014 ... ARDX ), a clinical-stage biopharmaceutical company focused ... announced positive results from its 371 patient ... patients with constipation-predominant irritable bowel syndrome (IBS-C).  ... and clinically meaningful improvement in IBS-C symptoms ...
(Date:10/1/2014)... October 1, 2014 Sophia Genetics, ... Sequencing (NGS) data analysis, today launches a unique CFTR ... analysis in a single NGS experiment. The CE-IVD marked ... of variants in a single NGS experiment with clinical ... not been possible to simultaneously analyse all relevant CFTR ...
Breaking Medicine Technology:Quantum Materials Scaling Up Photoactive Quantum Dot Production for Solar Power Generation 2Quantum Materials Scaling Up Photoactive Quantum Dot Production for Solar Power Generation 3Ardelyx Reports Positive Results from Its Phase 2b Clinical Trial Evaluating Tenapanor in IBS-C Patients 2Ardelyx Reports Positive Results from Its Phase 2b Clinical Trial Evaluating Tenapanor in IBS-C Patients 3Ardelyx Reports Positive Results from Its Phase 2b Clinical Trial Evaluating Tenapanor in IBS-C Patients 4Ardelyx Reports Positive Results from Its Phase 2b Clinical Trial Evaluating Tenapanor in IBS-C Patients 5Ardelyx Reports Positive Results from Its Phase 2b Clinical Trial Evaluating Tenapanor in IBS-C Patients 6Sophia Genetics Launches Full CFTR Analysis in Single Clinical Grade NGS Experiment 2
... , ... Food and Drug Administration (FDA) has notified health professionals, and ... -- from the use of negative pressure wound therapy (NPWT). ... therapy devices can help in the healing and closure of ...
... , ... a leading provider of software solutions to optimize clinical ... release of StudyOptimizer 4, the latest iteration of its ... pharmaceutical companies, DecisionView,s flagship product now includes advanced historical ...
Cached Medicine Technology:Negative Pressure Wound Devices Draw FDA Notice, Advice 2DecisionView Launches StudyOptimizer(TM) 4 2DecisionView Launches StudyOptimizer(TM) 4 3
Portex® Blue Line® cuffed endotracheal tubes come in a wide selection of sizes, each with a standard 15 mm ISO connector., ,Portex® Blue Line® endotracheal tubes are recognized world...
Portex® Blue Line® cuffed endotracheal tubes come in a wide selection of sizes, each with a standard 15 mm ISO connector., ,Portex® Blue Line® endotracheal tubes are recognized world...
... Plus™ Uncuffed Endotracheal Tube w. FlexiSlip™ Stylet, Murphy ... A quality Rusch endotracheal tube with a preloaded ... time and storage space. The stylet has a ... is designed with a soft distal tip to ...
Cuffed pediatric endotracheal tubes, available from 2.5 mm to 4.5 mm inside diameter. Ruschelit® PVC. Magill tip - nasoral. X-ray opaque line. Graduated. Single use. Sterile...
Medicine Products: