Navigation Links
Genetic Research Sheds Light on Adrenal Gland Tumor Risk
Date:12/14/2010

TUESDAY, Dec. 14 (HealthDay News) -- Scientists report that they have advanced their knowledge of genetic mutations associated with adrenal gland tumors by identifying 13 new potential variations.

Tumors called pheochromocytomas can affect the adrenal gland, which is located above the kidney. These tumors -- which are usually benign but can also be cancerous -- cause the adrenal gland to produce too much adrenaline, resulting in high blood pressure, headaches, heart palpitations, nausea and vomiting.

In the new study, which included nearly 1,000 people, the researchers identified 19 mutations in the FP/TMEM127 gene that may be associated with pheochromocytomas in the adrenal gland.

"Of these, 19 mutations found in 20 patients were considered of potential pathogenic significance. Thirteen of these variants were [new], while the remainder had been previously reported," Li Yao, of the University of Texas Health Science Center at San Antonio, and colleagues wrote in the report published in the Dec. 15 issue of the Journal of the American Medical Association.

The average age of patients when they developed FP/TMEM127-mutated tumors was 42.8 years and median (midpoint) age was 41.5 years.

"These observations support the existence of additional pheochromocytoma susceptibility genes, which may account for some of the genetically undefined cases," the authors wrote in a news release from the journal's publisher.

More information

The American Urological Association has more about pheochromocytoma.

-- Robert Preidt

SOURCE: Journal of the American Medical Association, news release, Dec. 14, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1

Related medicine news :

1. Rare Genetic Syndrome May Increase Colon Cancer Risk
2. Chinese Study Suggests New Way to Test for Genetic Diseases
3. New discovery prevents symptoms of rare genetic disorder
4. Genetic mutations associated with increased PSA and prostate cancer
5. Novel genetic mutation that causes the most common form of eye cancer discovered
6. Rare, Severe Form of Morning Sickness Appears to Be Genetic
7. Our normal genetics may influence cancer growth, too
8. Academies of science call for amendments to impracticable Genetic Diagnostics Act
9. New research shows genetic test for lung cancer risk prompts smokers to quit
10. Genetic Deletion Linked to Raised Risk of Autism, Schizophrenia
11. ASHG 2010: New research on implications of direct-to-consumer and clinical genetic testing
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Genetic Research Sheds Light on Adrenal Gland Tumor Risk
(Date:6/25/2016)... Montreal, Canada (PRWEB) , ... June 25, 2016 , ... ... the pursuit of success. In terms of the latter, setting the bar too high ... low, risk more than just slow progress toward their goal. , Research from ...
(Date:6/24/2016)... ... June 24, 2016 , ... Those who have experienced traumatic events may ... to unhealthy avenues, such as drug or alcohol abuse, as a coping mechanism. To ... for healthy coping following a traumatic event. , Trauma sufferers tend to feel a ...
(Date:6/24/2016)... ... ... was in a crisis. Her son James, eight, was out of control. Prone to extreme ... “When something upset him, he couldn’t control his emotions,” remembers Marcy. “If there was ... other children and say he was going to kill them. If we were driving ...
(Date:6/24/2016)... ... ... Global law firm Greenberg Traurig, P.A. announced that 20 Florida attorneys are ... for this recognition are considered among the top 2 percent of lawyers practicing within ... of this year’s Legal Elite Hall of Fame: Miami Shareholders Mark D. Bloom, ...
(Date:6/24/2016)... , ... June 24, 2016 , ... Comfort Keepers® of ... Cancer Society and the Road To Recovery® program to drive cancer patients to and ... other adults to ensure the highest quality of life and ongoing independence. Getting ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... June 24, 2016  Collagen Matrix, Inc., ("Collagen ... and manufacturing of collagen and mineral based medical ... that Bill Messer has joined the ... further leverage the growing portfolio of oral surgery, ... Bill joins the Collagen Matrix executive team ...
(Date:6/24/2016)... , June 24, 2016 ... the "Structural Electronics 2015-2025: Applications, Technologies, Forecasts" ... In-Mold Electronics, Smart Skin, Structural ... Structural electronics involves electronic and/or ... protective structures, replacing dumb structures such as vehicle ...
(Date:6/24/2016)... Research and Markets has announced the ... Tests" report to their offering. ... The World Market for Companion Diagnostics covers the ... analysis in the report includes the following: ... Kits) by Region (N. America, EU, ROW), 2015-2020 , ...
Breaking Medicine Technology: