Navigation Links
Genetic Pattern May Predict Leukemia Relapse
Date:5/13/2010

Children could be screened, treated more aggressively if deemed at risk, researchers say

THURSDAY, May 13 (HealthDay News) -- Researchers have linked a genetic pattern to the likelihood that patients with a severe form of childhood leukemia will relapse.

The finding could lead doctors to screen for the pattern and treat those who have it more aggressively from the time of diagnosis, the researchers added.

The kids in question have T-cell acute lymphoblastic leukemia, which accounts for about 15 percent of childhood leukemia cases.

While as many as 80 percent of children with the disease go into remission, about 20 percent relapse, study co-author Alex Beesley, of Perth's Telethon Institute for Child Health Research in Australia, said in a news release.

The prognosis for those patients can be grim, he said.

"In this study, we found a consistent pattern in the expression of five genes in patients that relapse," Beesley said. "Importantly, this pattern was found to hold true across multiple patient cohorts, the first time that such a robust gene signature of this kind has been found" for the type of leukemia in question.

"Patients identified using these markers could potentially be treated with more aggressive therapies from the outset to give them the best hope of achieving complete remission," Beesley said.

The study authors came to their conclusions after analyzing bone-marrow samples from children with leukemia. They found a genetic pattern that successfully predicted what would happen to 50 patients with the form of leukemia.

The findings were published online May 12 in the journal Molecular Cancer.

More information

For more about leukemia in kids, see the U.S. National Library of Medicine.



-- Randy Dotinga



SOURCE: BioMed Central, news release, May 11, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Walgreens Postpones Plans to Sell Do-It-Yourself Genetic Test
2. Genetic pattern that predicts leukemia relapse discovered
3. Resveratrol Supplement Company RevGenetics Welcomes New Chief Science Officer
4. Genetic Variants Tied to MS, Study Finds
5. UT Southwestern participates in nationwide study offering free lung tumor genetic testing
6. Genetic Research Sheds Light on Chronic Pain
7. High doses of antioxidant supplements induce stem cell genetic abnormalities
8. New research about human genetic diseases and human development
9. Genetics, Psychology May Trigger ADHD
10. Plant pathogen genetically tailors attacks to each part of host, say Stanford researchers
11. Study finds changes in fetal epigenetics throughout pregnancy
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/7/2016)... , ... December 07, 2016 , ... ... the passage of the most comprehensive mental health systems reform legislation in more ... of the President, and the commitment of our elected officials to improving mental ...
(Date:12/7/2016)... UTAH (PRWEB) , ... December 07, 2016 , ... ... announced the release of Smart Device Remote Control through a new partnership with ... all platforms and strengthens its mobile solutions to help businesses maximize their uptime ...
(Date:12/7/2016)... ... December 07, 2016 , ... It is vital for any ... useful, properly analyzed data. The team at Beckman Coulter has designed Kaluza, templates with ... speed' and the need to operate in a GLP (Good Laboratory Practice) fashion. , ...
(Date:12/7/2016)... ... December 07, 2016 , ... They are musicians and librarians, fashion designers and ... fathers, from New England and around the nation. What do they have in common? ... in a beautiful and compelling new photographic exhibit debuting Friday, December 9 at Logan ...
(Date:12/7/2016)... ... 2016 , ... Baciocco Brothers Insurance Agency, a northern California ... region, is initiating a charity event to raise support and awareness for the ... center in Sacramento works to provide area teens and families with treatment programs ...
Breaking Medicine News(10 mins):
(Date:12/8/2016)...  Economic growth in the United States will continue ... executives in their December 2016 Semiannual Economic Forecast. Expectations ... began in mid-2009, as indicated in the monthly ISM ... The manufacturing sector is optimistic about growth in 2017, ... and the non-manufacturing sector indicates that 14 of its ...
(Date:12/8/2016)...  Hanson Research, an innovative leader in the ... testing instruments for the pharmaceutical industry, announced today ... ("Teledyne"). The move is designed to deepen investments ... as well as expand resources for further market ... services. Logo - http://photos.prnewswire.com/prnh/20161208/446988LOGO ...
(Date:12/8/2016)... Henry Schein, Inc. (Nasdaq: HSIC ), ... to office-based dental, animal health and medical practitioners, today announced ... one of Poland,s largest full-service dental ... was announced on August 30, 2016. Henry Schein ... since 2014, and Marrodent marks the Company,s entry into ...
Breaking Medicine Technology: