Navigation Links
Genetic Pattern May Predict Leukemia Relapse
Date:5/13/2010

Children could be screened, treated more aggressively if deemed at risk, researchers say

THURSDAY, May 13 (HealthDay News) -- Researchers have linked a genetic pattern to the likelihood that patients with a severe form of childhood leukemia will relapse.

The finding could lead doctors to screen for the pattern and treat those who have it more aggressively from the time of diagnosis, the researchers added.

The kids in question have T-cell acute lymphoblastic leukemia, which accounts for about 15 percent of childhood leukemia cases.

While as many as 80 percent of children with the disease go into remission, about 20 percent relapse, study co-author Alex Beesley, of Perth's Telethon Institute for Child Health Research in Australia, said in a news release.

The prognosis for those patients can be grim, he said.

"In this study, we found a consistent pattern in the expression of five genes in patients that relapse," Beesley said. "Importantly, this pattern was found to hold true across multiple patient cohorts, the first time that such a robust gene signature of this kind has been found" for the type of leukemia in question.

"Patients identified using these markers could potentially be treated with more aggressive therapies from the outset to give them the best hope of achieving complete remission," Beesley said.

The study authors came to their conclusions after analyzing bone-marrow samples from children with leukemia. They found a genetic pattern that successfully predicted what would happen to 50 patients with the form of leukemia.

The findings were published online May 12 in the journal Molecular Cancer.

More information

For more about leukemia in kids, see the U.S. National Library of Medicine.



-- Randy Dotinga



SOURCE: BioMed Central, news release, May 11, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Walgreens Postpones Plans to Sell Do-It-Yourself Genetic Test
2. Genetic pattern that predicts leukemia relapse discovered
3. Resveratrol Supplement Company RevGenetics Welcomes New Chief Science Officer
4. Genetic Variants Tied to MS, Study Finds
5. UT Southwestern participates in nationwide study offering free lung tumor genetic testing
6. Genetic Research Sheds Light on Chronic Pain
7. High doses of antioxidant supplements induce stem cell genetic abnormalities
8. New research about human genetic diseases and human development
9. Genetics, Psychology May Trigger ADHD
10. Plant pathogen genetically tailors attacks to each part of host, say Stanford researchers
11. Study finds changes in fetal epigenetics throughout pregnancy
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/9/2016)... ... February 09, 2016 , ... ... to expand access to affordable hearing aids , increase industry transparency, and ... in the United States. , “For the average consumer, the hearing aid industry ...
(Date:2/9/2016)... ... February 09, 2016 , ... ... sealing company , is proud to announce that many of their franchises have ... customer service. The hard surface restoration franchises received customer recognition through positive reviews ...
(Date:2/8/2016)... ... 08, 2016 , ... The Federal Laboratory Consortium for Technology ... site houses a wealth of federal resources that businesses can leverage to further ... transfer (T2). As a network of over 300 federal laboratories, the FLC’s mission ...
(Date:2/8/2016)... ... ... who has struggled to quit smoking, a man who has struggled with hair loss – ... his problems – and he did. Now Nabat, a serial entrepreneur featured as the October ... to the world and better people's lives. His own experience with nicotine addiction led to ...
(Date:2/8/2016)... ... 2016 , ... The Bell Agency, a full service insurance ... their ongoing community enrichment program. The current campaign fundraises for Angels & Doves, ... being accepted at: http://www.angelsanddoves.com/donate.html . , Angels & Doves was founded in ...
Breaking Medicine News(10 mins):
(Date:2/9/2016)... DUBLIN , Feb. 9, 2016  Jazz Pharmaceuticals ... will report its 2015 fourth quarter and full year ... close of the financial markets.  Company management will host ... 4:30 p.m. EST/9:30 p.m. GMT to discuss fourth quarter ... business and financial update and guidance for 2016 financial ...
(Date:2/9/2016)... February 9, 2016 Amarantus BioScience ... on developing products for Regenerative Medicine, Neurology and Orphan ... presenting company at Source Capital Group,s 2016 Disruptive Growth ... 2016 in New York City . ... 10, 2016 at 12:30 pm by Gerald E. ...
(Date:2/9/2016)... , Feb. 9, 2016 The new report "Global Blood Monitoring ... Acuity Business Research & Consulting group reveals that global market for ... million in 2014 and expected to grow to US$ 24,830.1 million ... North America , Europe ... , Middle-East and Africa ...
Breaking Medicine Technology: