Navigation Links
Genetic Pattern May Predict Leukemia Relapse
Date:5/13/2010

Children could be screened, treated more aggressively if deemed at risk, researchers say

THURSDAY, May 13 (HealthDay News) -- Researchers have linked a genetic pattern to the likelihood that patients with a severe form of childhood leukemia will relapse.

The finding could lead doctors to screen for the pattern and treat those who have it more aggressively from the time of diagnosis, the researchers added.

The kids in question have T-cell acute lymphoblastic leukemia, which accounts for about 15 percent of childhood leukemia cases.

While as many as 80 percent of children with the disease go into remission, about 20 percent relapse, study co-author Alex Beesley, of Perth's Telethon Institute for Child Health Research in Australia, said in a news release.

The prognosis for those patients can be grim, he said.

"In this study, we found a consistent pattern in the expression of five genes in patients that relapse," Beesley said. "Importantly, this pattern was found to hold true across multiple patient cohorts, the first time that such a robust gene signature of this kind has been found" for the type of leukemia in question.

"Patients identified using these markers could potentially be treated with more aggressive therapies from the outset to give them the best hope of achieving complete remission," Beesley said.

The study authors came to their conclusions after analyzing bone-marrow samples from children with leukemia. They found a genetic pattern that successfully predicted what would happen to 50 patients with the form of leukemia.

The findings were published online May 12 in the journal Molecular Cancer.

More information

For more about leukemia in kids, see the U.S. National Library of Medicine.



-- Randy Dotinga



SOURCE: BioMed Central, news release, May 11, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Walgreens Postpones Plans to Sell Do-It-Yourself Genetic Test
2. Genetic pattern that predicts leukemia relapse discovered
3. Resveratrol Supplement Company RevGenetics Welcomes New Chief Science Officer
4. Genetic Variants Tied to MS, Study Finds
5. UT Southwestern participates in nationwide study offering free lung tumor genetic testing
6. Genetic Research Sheds Light on Chronic Pain
7. High doses of antioxidant supplements induce stem cell genetic abnormalities
8. New research about human genetic diseases and human development
9. Genetics, Psychology May Trigger ADHD
10. Plant pathogen genetically tailors attacks to each part of host, say Stanford researchers
11. Study finds changes in fetal epigenetics throughout pregnancy
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/27/2016)... KS (PRWEB) , ... June 27, 2016 , ... TopConsumerReviews.com ... retailers of Eyeglasses . , Millions of individuals in the United States and ... have become a way to both correct vision and make a fashion statement. Even ...
(Date:6/26/2016)... ... ... PawPaws brand pet supplements owned by Whole Health Supply is ... of felines. The formula is all-natural and is made from Chinese herbs that have ... Kidney Support Supplement Soft Chews are Astragalus Root Extract and Rehmannia Root Extract ...
(Date:6/25/2016)... TX (PRWEB) , ... June 25, 2016 , ... Austin ... of the American College of Mohs Surgery and to Dr. Russell Peckham for medical ... and highly effective treatment for skin cancer. The selective fellowship in Mohs Micrographic Surgery ...
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... As a ... Magna Cum Laude and his M.D from the David Geffen School of Medicine at ... returned to Los Angeles to complete his fellowship in hematology/oncology at the UCLA-Olive View-Cedars ...
(Date:6/24/2016)... Angeles, CA (PRWEB) , ... June 24, 2016 , ... ... surgery procedures that most people are unfamiliar with. The article goes on to state ... procedures, but also many of these less common operations such as calf and cheek ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , June 24, 2016 Research and ... Market for Companion Diagnostic Tests" report to their offering. ... for Companion Diagnostics The World Market for ... personalized medicine diagnostics. Market analysis in the report includes the ... Market (In Vitro Diagnostic Kits) by Region (N. America, EU, ...
(Date:6/24/2016)... 24, 2016  Arkis BioSciences, a leading innovator ... more durable cerebrospinal fluid treatments, today announced it ... funding is led by Innova Memphis, followed by ... private investors.  Arkis, new financing will accelerate the ... market release of its in-licensed Endexo® technology. ...
(Date:6/23/2016)... Research and Markets has announced the addition ... Chemical (Sugar, Petrochemical, Glycerin), Inorganic Chemical), Functionality (Filler, Binder, ... Forecast to 2021" report to their offering. ... excipients market is projected to reach USD 8.1 Billion ... forecast period 2016 to 2021. The ...
Breaking Medicine Technology: