Navigation Links
Genetic Mutations Boost Prostate Cancer Risk
Date:1/16/2008

These variants plus a family history can increase risk up to tenfold, study suggests,,,,

WEDNESDAY, Jan. 16 (HealthDay News) -- A new blood test that looks at five genetic variants could one day predict the risk of developing prostate cancer, a new study says.

Researchers found that among men with four of the five variants, the risk of prostate cancer is increased 400 percent to 500 percent, compared to men with none of the variants. And if a man has these gene variants and a family history of prostate cancer, his risk of developing the disease increases more than 900 percent.

"There are five genetic variants that have been shown to be associated with prostate cancer risk," said lead researcher Dr. Jianfeng Xu, a professor of epidemiology and cancer biology at Wake Forest University School of Medicine.

For the study, the researchers examined DNA samples from 2,893 men with prostate cancer and compared them with DNA of 1,781 healthy men. All the men participated in a prostate cancer study in Sweden.

The researchers found that each of these common genetic variants was independently associated with prostate cancer risk. The five variants plus a family history of prostate cancer accounted for 46 percent of prostate cancer patients.

The effect of each variant is too small to be useful in predicting the risk for prostate cancer, Xu said. "But if you have four of these variants your risk is increased fourfold, which is something we have never seen before," he said.

The five genetic locations include three on chromosome 8q24, one on chromosome 17q12, and one on chromosome 17q24.3, according to the report, published online Jan. 16 in the New England Journal of Medicine.

When family history of prostate cancer is added to the mix, the results become more striking, Xu said. "Family history is the sixth factor," he said. "For a man with five gene variants and a family history the
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. People with anorexia less likely to be blamed when biology, genetics explained
2. Years-Long Search Unlocks Deadly Genetic Disease
3. Brain imaging and genetic studies link thinking patterns to addiction
4. Human genetic variation -- Sciences Breakthrough of the Year
5. Top10 research advances include studies on genetics and stem cell research, stents
6. Twins study shows genetic basis for face and place recognition
7. Heart attack risk from smoking due to genetics
8. International research collaboration narrows focus on genetic cause of Kawasaki disease
9. Genetics May Boost Mexican-Americans Risk for Alcoholism
10. Studies elucidate genetic links between cancer and schizophrenia
11. Possible genetic predictor for response to lithium augmentation in depressed patients
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Genetic Mutations Boost Prostate Cancer Risk 
(Date:8/1/2014)... August 01, 2014 The American ... Gregg Harper (R-MS), and Peter Welch (D-VT), for ... Medicare Telehealth Parity Act of 2014, which improves ... this effort to improve healthcare access and affordability ... officer of ATA. "These cost-saving provisions are critical ...
(Date:8/1/2014)... On Monday, June 30th, the Quirk ... in San Francisco, CA. Now in its fourth year, ... Union Square hotel. , “We are excited about returning ... with ACA compliance issues,” Quirk Healthcare Foundation Executive Director, ... attendees guidance with NextGen implementation and use, electronic records ...
(Date:8/1/2014)... FRIDAY, Aug. 1, 2014 (HealthDay News) -- Although many parents ... many overlook a common choking hazard: food. Such ... wheeze and cough after eating a handful of nuts. ... not obvious if the coughing was related to his illness ... wasn,t a cold. A cashew had become lodged in his ...
(Date:8/1/2014)... 01, 2014 Over the past ... from innovative technologies that have enabled cosmetic dentists ... tooth color. Moreover, the burgeoning elderly population has ... tooth ailments. Due to long-term use of medications, ... have demanded dental fillings, veneers and implants. As ...
(Date:8/1/2014)... Oxford Gene Technology (OGT) is ... products include CytoSure heamatological cancer +SNP Array, CytoSure ... UPD array, CytoSure ISCA sample tracking spike-ins and ... such as targeted sequencing services, SureSeq Solid Tumour ... expression analysis, cytosure services and aCGH for CNV ...
Breaking Medicine News(10 mins):Health News:ATA Applauds Bill on Medicare Telemedicine Improvements 2Health News:Quirk Healthcare Foundation Hosts Fifth Annual California NextGen User Symposium and Launches First Annual Florida NextGen User Symposium 2Health News:Food Is a Common Choking Hazard for Kids, Doctor Says 2Health News:Cosmetic Dentists in the US Industry Market Research Report from IBISWorld Has Been Updated 2Health News:Cosmetic Dentists in the US Industry Market Research Report from IBISWorld Has Been Updated 3Health News:Oxford Gene Technology Market Size, Share, Analysis, Trends and Forecasts 2014 2Health News:Oxford Gene Technology Market Size, Share, Analysis, Trends and Forecasts 2014 3
... on the Atkins low-carbohydrate diet lose more weight than those ... pressure and cholesterol levels dropped considerably. ,On average, ... months. The average weight loss was 5.7 pounds for women ... diet and 3.5 pounds for those following the Zone weight-loss ...
... that a plane accident that left a father and young ... a suicide// crash. ,Two people were killed Monday ... the edge of a small local airport in Bedford - ... destroyed the house of the former mother-in-law of the divorced ...
... greens and beans aren't the only foods that pack ... healthy// start to pregnancy. ,Researchers now have ... a full day's worth of the nutrient in a ... week's online edition of the journal PNAS, Proceedings of ...
... the Chulalongkorn Hospital here removed a 60-cm-long sword that had ... and exited// near his left ear, news reports said Wednesday. ... a stable condition after the sword's removal from his face ... Tuesday, reported the Thai Rath newspaper. ,Ronnachai received ...
... Institute for Biological Studies, have discovered that silencing a gene ... reduce insulin resistance, in animal models, it will also help ... , The peptide in question is ucocortin 3. This ... produced in the insulin secreting cells of the pancreas and ...
... of a brain system that regulates appetite. The study also ... new drug therapies to help individuals lose weight. ... around 30 percent are obese. The study conducted by scientists ... the March issue of Cell Metabolism. ,The research ...
Cached Medicine News:Health News:Atkin’s Low-carb Diet Best for Weight Los 2Health News:Scientists Genetically Engineer Tomatoes With Enhanced Folate Content 2Health News:Scientists Explore Ways to Reduce Insulin Resistance by ‘handcuffing’ Gen 2Health News:Targeting SOCS-3 can Control Obesity 2
(Date:8/1/2014)... , August 1, 2014 ... Market by Type (Traditional Wound Closure, Anti infective), Basic ... (Artificial Skin & Skin Substitutes), Pressure Relief Devices, ... MarketsandMarkets, the global Wound Care Market is expected to ... in 2014, growing at a CAGR of 3.2% ...
(Date:8/1/2014)... Aug. 1, 2014  NxStage Medical, Inc. (Nasdaq: ... announced that Jeffrey H. Burbank , Chief Executive Officer, ... at the 34 th Annual Canaccord Genuity Growth Conference ... , on Wednesday, August 13 th at 4:30 ... available at http://ir.nxstage.com/ .  About NxStage ...
(Date:8/1/2014)... , Aug. 1, 2014  Neuland Laboratories ... active pharmaceutical ingredients (APIs), complex intermediates ... located in 85 countries, today announced financial results ... 2015, ended June 30, 2014. "Neuland,s ... work flow re-prioritization to accommodate certain customer needs, ...
Breaking Medicine Technology:Wound Care Market Worth $18.3 Billion by 2019 2Wound Care Market Worth $18.3 Billion by 2019 3NxStage to Present at the 34th Annual Canaccord Genuity Growth Conference 2Neuland Labs Reports First Quarter Fiscal Year 2015 Financial Results 2Neuland Labs Reports First Quarter Fiscal Year 2015 Financial Results 3
... AUSTIN, Texas, May 22, 2012 SmallCapVoice.com, Inc. ... Medical Marijuana, Inc. (PINKSHEETS: MJNA) is now available. ... . Recent company activity and highlights: ... approximately $1.21 million on gross revenues of $1.79 ...
... Laboratory, Inc. (HDL, Inc.), a CAP accredited leader in ... with a non-restricted educational grant to further its mission ... the United States. In addition to the grant, HDL, ... of the 2012 Annual Scientific Sessions in Scottsdale, Arizona ...
Cached Medicine Technology:Medical Marijuana Inc. (MJNA) Corporate Update on Industry Company Services and Future Development. First Audio-Webcast Interview With SmallCapVoice.com in Quarterly Series 2Medical Marijuana Inc. (MJNA) Corporate Update on Industry Company Services and Future Development. First Audio-Webcast Interview With SmallCapVoice.com in Quarterly Series 3Medical Marijuana Inc. (MJNA) Corporate Update on Industry Company Services and Future Development. First Audio-Webcast Interview With SmallCapVoice.com in Quarterly Series 4Health Diagnostic Laboratory, Inc. Provides Grant to Support National Lipid Association, Sponsors 2012 Annual Scientific Sessions in Scottsdale, Arizona 2
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: