Navigation Links
Genetic Mutations Boost Prostate Cancer Risk
Date:1/16/2008

These variants plus a family history can increase risk up to tenfold, study suggests,,,,

WEDNESDAY, Jan. 16 (HealthDay News) -- A new blood test that looks at five genetic variants could one day predict the risk of developing prostate cancer, a new study says.

Researchers found that among men with four of the five variants, the risk of prostate cancer is increased 400 percent to 500 percent, compared to men with none of the variants. And if a man has these gene variants and a family history of prostate cancer, his risk of developing the disease increases more than 900 percent.

"There are five genetic variants that have been shown to be associated with prostate cancer risk," said lead researcher Dr. Jianfeng Xu, a professor of epidemiology and cancer biology at Wake Forest University School of Medicine.

For the study, the researchers examined DNA samples from 2,893 men with prostate cancer and compared them with DNA of 1,781 healthy men. All the men participated in a prostate cancer study in Sweden.

The researchers found that each of these common genetic variants was independently associated with prostate cancer risk. The five variants plus a family history of prostate cancer accounted for 46 percent of prostate cancer patients.

The effect of each variant is too small to be useful in predicting the risk for prostate cancer, Xu said. "But if you have four of these variants your risk is increased fourfold, which is something we have never seen before," he said.

The five genetic locations include three on chromosome 8q24, one on chromosome 17q12, and one on chromosome 17q24.3, according to the report, published online Jan. 16 in the New England Journal of Medicine.

When family history of prostate cancer is added to the mix, the results become more striking, Xu said. "Family history is the sixth factor," he said. "For a man with five gene variants and a family history the
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved  

0

GOOD

Page: 1 2 3

Related medicine news :

1. People with anorexia less likely to be blamed when biology, genetics explained
2. Years-Long Search Unlocks Deadly Genetic Disease
3. Brain imaging and genetic studies link thinking patterns to addiction
4. Human genetic variation -- Sciences Breakthrough of the Year
5. Top10 research advances include studies on genetics and stem cell research, stents
6. Twins study shows genetic basis for face and place recognition
7. Heart attack risk from smoking due to genetics
8. International research collaboration narrows focus on genetic cause of Kawasaki disease
9. Genetics May Boost Mexican-Americans Risk for Alcoholism
10. Studies elucidate genetic links between cancer and schizophrenia
11. Possible genetic predictor for response to lithium augmentation in depressed patients
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Genetic Mutations Boost Prostate Cancer Risk 
(Date:5/19/2013)... The muscles in the human body are ... of the biggest and most significant nervous systems in ... system comprises of peripheral nerves that reside outside of ... that the limbs and hands, as well as other ... damaged due to trauma or physical injury, their functionality ...
(Date:5/19/2013)... Los Angeles, California (PRWEB) May 19, 2013 ... more damage than just losing sleep, or annoying your ... 9, 2013 report by CNY Central (“Snoring and Teeth ... a certain type of teeth grinding can be hard ... around 12 million Americans, and one of its symptoms ...
(Date:5/19/2013)... Christi, TX (PRWEB) May 19, 2013 ... security systems companies. Homeowners who are considering an ... and services of the nation's leading security system providers ... systems reviews the best DIY home security system ... Every year 6Webs.com reviews dozens of home security companies ...
(Date:5/19/2013)... 19, 2013 The report “Feed Additives ... & Forecasts up to 2017” published by MarketsandMarkets, defines ... analysis and forecasting of the global volume and revenue ... driving and restraining factors for the global market with ... challenges. The market is segmented and revenue is forecasted ...
(Date:5/19/2013)... (PRWEB) May 19, 2013 The Pradaxa ... Management Conference was recently convened for hundreds of ... litigation now underway in U.S. District Court, Southern District ... Court’s website on May 14th, the Conference addressed the ... also reported during the Conference that Defendants submitted a ...
Breaking Medicine News(10 mins):Health News:Ultimate Neuropathy Support System Launched by Neuracel - Reaching New Heights in Herbal Medication for Peripheral Neuropathy 2Health News:Dr. Kanani, Woodland Hills Dentist: Dangers of Tooth Damage and Obstructive Sleep Disorder 2Health News:Dr. Kanani, Woodland Hills Dentist: Dangers of Tooth Damage and Obstructive Sleep Disorder 3Health News:Top Rated DIY Home Security System Companies Published by 6Webs.com 2Health News:Feed Additives Market to Reach $19.5 Billion by 2017 at a CAGR of 3.8% - New Report by MarketandMarkets 2Health News:Feed Additives Market to Reach $19.5 Billion by 2017 at a CAGR of 3.8% - New Report by MarketandMarkets 3Health News:Pradaxa Lawyers at Bernstein Liebhard LLP Report on Recent Status Conference in Federal Pradaxa Litigation 2Health News:Pradaxa Lawyers at Bernstein Liebhard LLP Report on Recent Status Conference in Federal Pradaxa Litigation 3
... to the British throne has extended his generosity and assistance ... dire need of measures to get back the lost splendour. ... Clarence House, his London residence, to launch an international campaign ... a chain of palaces and temples built by Nepal's Malla ...
... a B.C. youngster a bowel, liver, pancreas and stomach. Lori MacIver ... of her son. She said, "They were telling me to prepare ... ,Her son Gairett, 18, is now recovering following a high-risk, ... now has a new bowel, stomach, liver and pancreas, all from ...
... of American families has revealed that only half of drug- ... doing so often gives positive results to 82% of them. ... Gallup poll, the USA Today/HBO Family Drug Addiction poll revealed ... addicted to drugs or alcohol. ,The findings of the ...
... milestone in the mapping of the bovine genome, which will ... disease// control in cattle. This research is slated to benefit ... up on a sequence of 2.9 million DNA base pairs, ... in one pair, which can alter the productivity of the ...
... technique for pain relief has been developed at the ... a lot of promise// in alleviating extreme pain, during ... Neurolytic block, which is a concoction of anaesthetic and ... into the para vertebral space. This works by blocking ...
... virus has afflicted 487 children and has claimed the ... the state.,The disease has been recently named// as Acute ... family welfare ministry. ,Experts at the Sanjay ... of professor in Microbiology department, Dr TN Dhole, had ...
Cached Medicine News:Health News:A Princely Assistance to the Nepal Heritage 2Health News:Rare Transplant Gives B.C Youngster 4 New Organs 2Health News:Rare Transplant Gives B.C Youngster 4 New Organs 3Health News:Eastern UP hit by killer virus – Coxsacki 2
(Date:5/18/2013)... YORK , May 18, 2013 ... law firm, is investigating potential securities fraud at ... AVEO). (Logo: http://photos.prnewswire.com/prnh/20120119/MM38856LOGO ) ... Company and its executives violated federal securities laws ... the Company,s Phase III drug trials for Tivopath ...
(Date:5/17/2013)... -- Medical devices are any medical items that are ... of their different mechanisms, actions and regulatory requirements, medical ... drug trails due to their unique clinical practices. Currently, ... both safety and efficacy (which is left to the ... as the SFDA) evaluate MDs for both safety and ...
(Date:5/17/2013)... 17, 2013  Sorrento Therapeutics, Inc. (OTCBB: SRNE; ... Technology Small Business Technology Transfer Research (STTR) grant ... Infectious Diseases (NIAID), a division of the National ... novel human antibody therapeutics to combat Staphylococcus ... infections, including methicillin-resistant S. aureus (MRSA), ...
Breaking Medicine Technology:Faruqi & Faruqi, LLP Encourages Investors Who Suffered Losses In Excess Of $100,000 Investing In AVEO Pharmaceuticals, Inc. To Contact The Firm 2Statistical Challenges in Medical Device Trail Evaluation 2Sorrento Therapeutics, Inc. announces its approach to developing human antibody therapeutics against MRSA receives continued support from the National Institute of Allergy and Infectious Diseases 2Sorrento Therapeutics, Inc. announces its approach to developing human antibody therapeutics against MRSA receives continued support from the National Institute of Allergy and Infectious Diseases 3Sorrento Therapeutics, Inc. announces its approach to developing human antibody therapeutics against MRSA receives continued support from the National Institute of Allergy and Infectious Diseases 4
... Optimer Pharmaceuticals, Inc. (Nasdaq: OPTR ) ... difficile infection using National health insurance claims and ... 2, 2011 at the 21st Annual Scientific ... (SHEA).   (Logo:   http://photos.prnewswire.com/prnh/20090413/LA97352LOGO )Poster Presentation ...
... March 27, 2011 /PRNewswire-Asia/ -- Guangzhou General Hospital of ... the first Chinese regional military and civilian ... (mHealth) system is now in full operation. This network ... and a Remote Electrocardiograph (ECG) Diagnostic Center run by ...
Cached Medicine Technology:Optimer Pharmaceuticals Announces Presentation at Upcoming SHEA Annual Meeting Regarding Hospital CDI Patients at Risk of Recurrence and Mortality 2Chinese Army Established the First Chest Pain Rescue Network in China by Using IVT mHealth System 2
... The instrument includes the ... has increased illumination for ... illumination. The Copeland retinoscope ... handle, and extended battery ...
... stereopsis from 800 to 40 ... young as 2 years of ... from left to right., ,Randot ... Book #1: 200 & 100 ...
... EasyEye is the only handheld non-contact tonometer with ... is streamlined, quiet and now, with constant ... a gentle puff of air. You can prove ... on the patient's hand before you start. ...
... 2000 Phenytoin Assay is a ... use in the quantitative analysis ... or plasma. Kits are packaged ... Roche COBAS MIRA, COBAS MIRA ...
Medicine Products: