Navigation Links
Genetic Mutation Linked to Prostate Cancer in Blacks
Date:2/22/2010

Finding may explain higher incidence among blacks than whites

MONDAY, Feb. 22 (HealthDay News) -- Researchers have identified a mutation in a small number of black American men with a family history of prostate cancer.

This germline mutation of the androgen receptor (AR) may prove to be a genetic biomarker for familial prostate cancer in the black American male population, according to the team at Louisiana State University in New Orleans.

Black American men have a higher incidence of prostate cancer than any other racial group. The small amount of research that's been done on the role that AR mutations play in prostate cancer has been limited to white men.

This study found a germline AR-A1675T substitution mutation in the DNA-binding domain in three black American men with a family history of early-onset prostate cancer. This mutation may contribute to prostate cancer by "altering the AR DNA-binding affinity and its response to androgens, non-androgenic steroids or anti-androgens," according to a news release about the study.

The study was published online this week in the Asian Journal of Andrology.

Further research is needed to learn more about the role this mutation plays in prostate cancer in black Americans, the researchers said.

More information

The U.S. Centers for Disease Control and Prevention has more about prostate cancer.



-- Robert Preidt



SOURCE: Asian Journal of Andrology, news release, Feb. 22, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Page: 1

Related medicine news :

1. Many Parents Share Genetic Test Findings With Kids
2. Genetic predisposition increases childhood asthma risk
3. New Alzheimers findings: High stress and genetic risk factor lead to increased memory decline
4. Test Spots Genetic Damage Done by Smoking
5. Scientists demonstate link between genetic variant and effectiveness of smoking cessation meds
6. Scientists highlight benefits of genetic research in sport, but warn of ethical concerns
7. Genetics Hold Promise, Challenges for Cancer Care
8. Researchers genetically engineer micro-organisms into tiny factories
9. Study Questions Genetic Screening for Treatable Diseases
10. Researchers provide genetic associations from a genome-wide scan for cardiovascular disease traits
11. Genetic variation affects smoking cessation treatment
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/18/2017)... (PRWEB) , ... August 18, 2017 , ... ... and financial planning firm that serves residential and commercial clients in the greater ... drive to raise community support for the fight against cancer. , Founded by ...
(Date:8/18/2017)... ... 18, 2017 , ... With over 16,000 active patients, BodyLogicMD, ... therapy and integrative medicine, has become a frontrunner for people seeking help with ... andropause, thyroid disorder and adrenal insufficiencies. , Founded in 2003 by Patrick ...
(Date:8/18/2017)... ... August 18, 2017 , ... Inc. magazine has ranked American ... prestigious ranking of the nation's fastest-growing private companies. This marks the eighth time in ... 5000 ranking . This year’s ranking reflects ASH’s 76 percent overall revenue growth from ...
(Date:8/18/2017)... ... 2017 , ... “Dangerous Inheritance”: a mystery about saving the family farm. ... Southwest Nebraska where she was raised on a farm. As Diane wrote this ... but the friendships and mantra of ‘neighbors helping neighbors’ have always been a large ...
(Date:8/18/2017)... ... 18, 2017 , ... “Depressed: Super Heroes of the Bible”: a gripping ... stories and the relevance these tales may have on the reader’s life. “Depressed: Super ... special education teacher, Jessica spends much of her time enjoying nature and her family ...
Breaking Medicine News(10 mins):
(Date:8/3/2017)... Aug. 3, 2017  Opioid addiction and other drugs ... healthcare costs and threatening outcomes, were problems taken on ... IVD industry that support them, met this week. This ... said that drugs of abuse, procalcitonin and acute kidney ... the organization,s 69th meeting in San Diego, ...
(Date:8/2/2017)... and BENTON, Ky. , Aug. 2, 2017   Marshall ... to its environmental services (ES) team to proactively reduce the risk of hospital-acquired infections (HAIs). ... UV disinfection robot that uses UVC light energy to kill deadly pathogens such as ... Tru-D ... Tru-D in action ...
(Date:8/2/2017)... Aug. 2, 2017 CaryRx, a next-generation full-service pharmacy, ... service for patients in the Washington D.C. ... pharmacy by providing delivery of medications through the convenience of ... delivery or delivered within one hour to any location in ... to bring this invaluable service to Washington D.C. ...
Breaking Medicine Technology: