Navigation Links
Genetic Marker for Aggressive Prostate Cancer Found
Date:1/11/2010

aggressive disease.

Several dozen genetic variants have been linked to a greater risk of developing prostate cancer, but this is the first to be associated with aggressiveness of the disease, Xu said.

"The entire field has a long way to go, but this is an important first step," he said.

One indication of the distance to be traveled is the finding that the variant is located in a part of the genome where no gene has been found. This is not an uncommon finding, Xu explained, since many of the risk-associated variants are not in genes. "Our understanding of how the genome works is very limited," he said.

Still, much can be accomplished with what is known, with appropriate changes in strategy, Xu noted. Until now, the focus in prostate cancer has been on finding variants that affect the risk of developing the malignancy. "If you use that approach, it is difficult to distinguish aggressive from non-aggressive cancers," he said. "If you compare two groups of patients, one with indolent disease, one not, you are more likely to find those variants."

A second study comparing the genomes of 1,000 men with aggressive prostate cancer and an equal number with the indolent form of the disease is under way, with results expected to be published later this year, Xu added. The hope is to find a series of variants that might eventually be used by physicians in a screening test to help determine when more than watchful waiting is needed for prostate cancer, he said.

"Our work is too early to say whether it will have a clinical impact," said William B. Isaacs, a professor of urology and oncology at Johns Hopkins Medical Institutions, and a member of the research team. "It wont change the approach to identifying men with the aggressive form of prostate cancer. But this demonstrates that such markers do exist, and by studying them we may be able to understand the biological pathways that contribute to making prostate cancer mor
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved

Page: 1 2 3

Related medicine news :

1. Genetic variant associated with aggressive form of prostate cancer
2. Biologists develop efficient genetic modification of human embryonic stem cells
3. Adding a genetic supertool
4. Chicago Cancer Genome Project studies genetics of 1,000 tumors
5. U-M Study Reveals Surprising Lack of Genetic Diversity in the Most Widely Used Human Embryonic Stem Cell Lines
6. Genetic Test May Someday Help Spot Breast Cancer
7. New License Agreement with University of Colorado Gives Viral Genetics, Inc., Right to Develop Cancer Therapies
8. Genetic variations indicate risk of recurrence, secondary cancer among head and neck cancer patients
9. Interleukin Genetics Receives Approval To Sell its PST(R) Periodontal Disease Genetic Test in New York
10. Genetic studies reveal new causes of severe obesity in childhood
11. Advances in Genetic Understanding and Treatment Protocols Lead to Significant Progress in Leukemia and Myeloproliferative Disorders
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/1/2015)... ... 2015 , ... BeverlyD, owner and founder of BeverlyD Luxe Organic Hair Care, ... small business donation to kick off the campaign for healing and Well-Being. , BeverlyD ... a complete line of raw, organic hair care products, as well as her book, ...
(Date:7/31/2015)... (PRWEB) , ... July 31, 2015 , ... When the ... stuff, Super-Sod debuted their new type of sod called Leisure Time(TM) zoysia . ... in process. , To commemorate introduction of this new type of sod, Super-Sod is ...
(Date:7/31/2015)... ... July 31, 2015 , ... Recently touted by Becker’s ... predictive health analytics , Jvion continues to disrupt the predictive analytic and big ... targets patient and population level illness to drive prevention and better health outcomes. ...
(Date:7/31/2015)... ... 2015 , ... Jacksonville-based drug and alcohol rehabilitation center, Lakeview ... The medical community, social workers, law enforcement, and government officials are all invited ... effort to better understand and combat sex trafficking. Lead by sex trafficking expert ...
(Date:7/31/2015)... ... July 31, 2015 , ... According to the article published July 27 on ... courthouse was contained and extinguished by the city’s fire department before it caused major damage ... the time of the fire, and it was a fire alarm system that tipped off ...
Breaking Medicine News(10 mins):Health News:March4thforWellBeing Foundation Kickoff 2Health News:Super-Sod Introduces Leisure Time(TM) Zoysia Grass with an Adirondack Chair Promotion 2Health News:Jvion Showcased as Leader in the Predictive Analytic Market 2Health News:Lakeview Health Links Sex Trafficking and Addiction in Special Jacksonville Educational Workshop 2Health News:Lakeview Health Links Sex Trafficking and Addiction in Special Jacksonville Educational Workshop 3Health News:Article on Recent Pasadena Courtroom Fire Highlights the Effectiveness of Fire Alarm Systems, Says Fire Protection Group Inc 2Health News:Article on Recent Pasadena Courtroom Fire Highlights the Effectiveness of Fire Alarm Systems, Says Fire Protection Group Inc 3
... a better choice, researchers say , , TUESDAY, Sept. 11 (HealthDay ... of diabetics to control blood sugar, greatly increases their risk ... drug does not up users, overall risk of death, however, ... benefits has shifted, and this needs to be factored into ...
... Provide New Levels of Protection, PITTSBURGH, Sept. ... leading developer of sophisticated safety equipment, today,announced that ... certified as meeting new rigorous performance requirements adopted,by ... M7 Air,Mask is the first device of its ...
... (Nasdaq: EMITF ) ("EMI") announced today that it had ... offering,of Series E Notes and Series F Notes in the ... be conducted in two separate tenders based on the,annual interest ... The Offering,Prospectus provides that the maximum interest rate of the ...
... 11, 2007 - A history of maternal epilepsy and ... later in life, says a new study published in ... Bergen and Norwegian Institute of Public Health, Bergen, Norway, ... with and without epilepsy, and found a correlation between ...
... Aviv Universitys Sackler School of Medicine is, quite simply, a ... of a small number of surgeons in the world who ... has developed a novel laser device that promises to revolutionize ... now, is expected to give most practicing eye surgeons the ...
... ... troops, PHOENIX, Sept. ... returning Guard members, TriWest Healthcare,Alliance, the Department of Defense,s TRICARE contractor in ... first Combat,Stress Video Conference. The conference, being held from 2 to 5 ...
Cached Medicine News:Health News:Diabetes Drug Avandia Boosts Heart Risks: Study 2Health News:Diabetes Drug Avandia Boosts Heart Risks: Study 3Health News:MSA's Next-Generation Breathing Apparatus for Firefighters First to Receive Full NFPA Approval 2Health News:MSA's Next-Generation Breathing Apparatus for Firefighters First to Receive Full NFPA Approval 3Health News:Elbit Medical Imaging Ltd. Announces Publication of a Prospectus in Israel 2Health News:Elbit Medical Imaging Ltd. Announces Publication of a Prospectus in Israel 3Health News:Elbit Medical Imaging Ltd. Announces Publication of a Prospectus in Israel 4Health News:Glaucoma surgery in the blink of an eye 2Health News:TriWest and Montana VA Launch PTSD Video Conference to Reach Rural Health Care Providers 2
(Date:7/31/2015)... July 31, 2015 The Physician-Patient Alliance ... on July 28, 2015, "Surviving Your Hospital Stay: ... for Patient Safety." A sentence was ... read: "PPAHS is a member of ... Opioids. For more information on the National Coalition to ...
(Date:7/31/2015)... TAMPA, Fla. , July 31, 2015 /PRNewswire/ ... announced today that it has made a structured ... -based company specializing in milling, micronization and ... investment will help grow Powdersize,s business while simultaneously ... solutions to Xcelience,s portfolio of capabilities. ...
(Date:7/31/2015)...  Semler Scientific, Inc. (Nasdaq: SMLR ), a ... insurers and physician groups, today reported financial results for ... "In the second quarter of 2015, Semler reported ... 54%, quarter over quarter revenue growth of 8%, and ... FloChec® units of 18%," said Doug Murphy-Chutorian, M.D., chief ...
Breaking Medicine Technology:Xcelience Makes Structured Cash Investment in Powdersize 2Xcelience Makes Structured Cash Investment in Powdersize 3Semler Reports Second Quarter 2015 Financial Results 2Semler Reports Second Quarter 2015 Financial Results 3Semler Reports Second Quarter 2015 Financial Results 4Semler Reports Second Quarter 2015 Financial Results 5Semler Reports Second Quarter 2015 Financial Results 6
... - Tercica, Inc.,(NASDAQ:TRCA) today announced that Company management ... Unterberg, Towbin,Emerging Growth Opportunities Conference at the Mandarin ... 2007 at 4:00 p.m. Eastern,time (1:00 p.m. Pacific ... will be available,via the Internet by visiting the ...
... 2, 2007 - Accelrys, Inc.,(NASDAQ:ACCL), the leading provider ... that its CFO,Rick Russo, will present at the ... York on July 11, 2007 at,10:30 a.m. ET. ... Hotel July 10th-12th. In attendance will be securities,analysts, ...
Cached Medicine Technology:Accelrys to Present to Investors at C.E. Unterberg Emerging Growth,Opportunities Conference 2
The Triage Profiler Shortness of Breath Panel provides rapid risk assessment and differential diagnosis of patients presenting to the emergency department with shortness of breath and risk assessment...
... an affordable path to Sonesta flexibility. ... and back adjustments. Packaged with basic ... line of Sonesta add-ons, allowing you ... your needs; complete Sonesta flexibility at ...
... The Sonesta 6202 is ... Packaged with our most popular ... equipped for a myriad of ... powerful (yet quiet) motors allow ...
... bilirubin levels with no pain, no waiting ... the traditional heel stick method or blood ... without regard to gender, gestational age or ... the babys forehead, which reduces the risk ...
Medicine Products: