Navigation Links
Genetic Links Seen Between Bipolar Illness and Schizophrenia
Date:9/22/2011

THURSDAY, Sept. 22 (HealthDay News) -- There is a genetic link between schizophrenia and bipolar disorder, two common and often disabling brain disorders, a new study indicates.

Researchers identified 11 genetic regions, including six that had never been discovered before, which play a role in people's risk for these mental illnesses. The findings, they say, provide new insight into the causes of both conditions.

"Schizophrenia and bipolar disorder are debilitating illnesses affecting millions of people around the world, and existing therapies for these people are ineffective as long-term options," the bipolar study's lead author Dr. Pamela Sklar, chief of the division of psychiatric genomics in the department of psychiatry and a professor of psychiatry at Mount Sinai School of Medicine, said in a news release. "We have been hard at work trying to determine genetic risk for these diseases so that we can intervene earlier and develop new therapies with which to treat them. Through this research, we are an important step closer to making that possible."

Researchers examined the DNA of 7,481 people with bipolar disorder as well as 9,250 healthy people. In a separate study, another team of scientists evaluated the same DNA sites in more than 17,000 people with schizophrenia.

In these two studies, the researchers found several DNA sites also known as DNA variants in certain genes were linked with schizophrenia and bipolar disorder. In some cases, certain variants were associated with both disorders. They argued the findings could help scientists identify new treatments for these mental illnesses enabling them to treat them earlier on and more effectively.

"Until recently, psychiatric research has understood the genetic basis of mental illness only very poorly," Dr. Shaun Purcell, an associate professor of psychiatry at Mount Sinai School of Medicine and co-author on the schizophrenia study, said in a news release. "Our research has helped us begin to elucidate the genetic structure of bipolar disorder and schizophrenia, and will, we hope, provide a new foundation to build upon in improving treatments and the quality of life of these patients."

The research was published in the Sept. 18 issue of Nature Genetics.

More information

The U.S. National Institute of Mental Health provides more information on genetics and mental illness.

-- Mary Elizabeth Dallas

SOURCE: Mount Sinai School of Medicine, news release, September 20, 2011.


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Certain genetic profiles associated with recurrence-free survival for non-small cell lung cancer
2. Obstructive Sleep Apnea in Kids May Have Genetic Cause
3. Epigenetic signals differ across alleles
4. Study reveals genetic link between mammographic density and breast cancer
5. Genetic Risk Score Doesnt Spot Heart Trouble in Women
6. Penn researchers find genetic link to leukemias with an unknown origin
7. Scientists Spot Genetic Fingerprints of Individual Cancers
8. Genetic health risks in children of assisted reproductive technology
9. Genetic Mutation Linked to Prostate Cancer in Blacks
10. Protecting the brain from of a deadly genetic disease
11. Protecting the brain from a deadly genetic disease
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Genetic Links Seen Between Bipolar Illness and Schizophrenia
(Date:6/24/2016)... ... 24, 2016 , ... People across the U.S. are sharpening their pencils and ... essay contest in which patients and their families pay tribute to a genetic counselor ... National Society of Genetic Counselors (NSGC) Annual Education Conference (AEC) this September. , ...
(Date:6/24/2016)... New York, NY (PRWEB) , ... June 24, ... ... lifestyle publication Haute Living, is proud to recognize Dr. Barry M. Weintraub as ... believes that “the most beautiful women in the world, and the most handsome ...
(Date:6/24/2016)... ... June 24, 2016 , ... Strategic Capital ... area economy by obtaining investment capital for emerging technology companies. SCP has ... have already resulted in more than a million dollars of capital investment for ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... Venture ... Golf Classic Tournament held on June 20th at the Woodmont Country Club at ... Luke’s Wings, an organization dedicated to helping service members that have been wounded in ...
(Date:6/24/2016)... ... June 24, 2016 , ... Advanced Plastic Surgery Institute ... pageant as its official Medspa Sponsor. Dr. Josh Olson, a board-certified plastic surgeon, ... , Dr. Olson says the decision to support the pageant in an official ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... , June 27, 2016 Jazz Pharmaceuticals ... waiting period under the Hart-Scott-Rodino Antitrust Improvements Act of ... acquisition of Celator Pharmaceuticals, Inc. ("Celator"; Nasdaq: ... p.m. (Eastern Daylight Time). As previously announced ... into a definitive merger agreement under which Jazz Pharmaceuticals ...
(Date:6/26/2016)... June 26, 2016 Story ... operating models within the health care industry is causing ... efficiency , Deloitte offers a suite of solutions ... issues impacting efficient cost optimization: labor resource analysis, revenue ... services facilitate better outcomes and better economics ...
(Date:6/24/2016)... June 24, 2016  Collagen Matrix, Inc., ("Collagen ... and manufacturing of collagen and mineral based medical ... that Bill Messer has joined the ... further leverage the growing portfolio of oral surgery, ... Bill joins the Collagen Matrix executive team ...
Breaking Medicine Technology: