Navigation Links
Genetic Factors for Smoking Boost Chronic Bronchitis Risk
Date:2/29/2008

Swedish study says it's first to quantify heritability of the disease

FRIDAY, Feb. 29 (HealthDay News) -- While smoking is the leading risk factor for chronic bronchitis, genes also play a major role in the development of the disease, say Swedish researchers.

The study, which analyzed data on more than 40,000 twins born in 1958 or earlier, found that inherited genes accounted for 40 percent of the risk for chronic bronchitis and that 14 percent of the genetic risk was also linked to a genetic predisposition to smoke, whether or not a person actually smoked.

The findings are published in the first issue for March of the American Journal of Respiratory and Critical Care Medicine.

"(This) study on the population-based Swedish Twin Registry, showing a genetic effect for the development of chronic bronchitis that does not differ by sex, is the first to our knowledge to quantify heritability of the disease," Jenny Hallberg, of the department of public health sciences at Karolinska Institutet in Stockholm, said in a prepared statement.

Previous research had suggested that women were more likely than men to develop chronic bronchitis, so the findings that prevalence didn't differ by sex pointed to a number of intriguing possibilities, she noted.

"It is possible that women are more prone to report symptoms. Or, more likely, this could be an effect of smoking being more harmful for women due to their smaller lungs from start [exposure to cigarette smoke relative to body size]," Hallberg wrote.

The finding that genetic factors that contribute to chronic bronchitis are largely independent of smoking shouldn't be interpreted to mean that smoking has no effect on the disease, she cautioned.

"Although there was some genetic interplay, it is safe to say that smoking itself, and not the genes that predispose one to smoking, is a larger risk factor in developing chronic bronchitis of environmental exposures -- primarily smoking -- than genetic predisposition. This is true of both men and women," Hallberg wrote.

Chronic bronchitis and emphysema account for most cases of chronic obstructive pulmonary disease (COPD).

More information

The American Academy of Family Physicians has more about chronic bronchitis.



-- Robert Preidt



SOURCE: American Thoracic Society, news release, Feb. 29, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Genetic factors in smoking also increase risk of chronic bronchitis
2. Dr. Robert Leonard First in New England to Offer Genetic Test for Male Pattern Baldness
3. U of Minn researchers discover genetic cancer link between humans and dogs
4. New genetic association with schizophrenia found by researchers
5. Genetic mutation found in peripheral artery disease
6. Genetic town halls to be held in 5 US cities
7. DNA Findings Reveal Genetic History of Humans
8. Bone complications due to cystic fibrosis have a genetic cause, according to an MUHC study
9. New Genetic Technology IDs Virus That Killed Transplant Recipients
10. American Academy of Dermatology Research Confirms Genetic Skin Barrier Defect Linked to Eczema
11. Genetics Researcher at Childrens Hospital Selected as Howard Hughes Medical Institute Investigator
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Genetic Factors for Smoking Boost Chronic Bronchitis Risk
(Date:10/13/2017)... ... 2017 , ... Global Healthcare Management’s 4th Annual Kids Fun Run brought out ... free event, sponsored by Global Healthcare Management’s CEO, Jon Letko, is aimed at getting ... children of all ages; it is a non-competitive, non-timed event, which is all about ...
(Date:10/13/2017)... ... October 13, 2017 , ... Coveros, ... Development, has been awarded a contract by the Center for Medicare and Medicaid ... to accelerate the enterprise use of Agile methodologies in a consistent and high ...
(Date:10/12/2017)... ... 12, 2017 , ... First Healthcare Compliance (FHC), an industry ... a range of technology and learning solutions at the 68th Annual American Healthcare ... be held October 14–18, 2017 at the Mandalay Bay Resort in Las Vegas, ...
(Date:10/12/2017)... ... October 12, 2017 , ... The company ... of today’s consumer and regulatory authorities worldwide. From Children’s to Adults 50+, every ... meet the highest standard. , These products are also: Gluten Free, Non-GMO, ...
(Date:10/12/2017)... ... , ... Asante, a nationally recognized health system in southern ... home health joint venture through an agreement, effective October 1, 2017, to create ... health company with Asante, delivering clinically integrated care, for the past eight years. ...
Breaking Medicine News(10 mins):
(Date:10/11/2017)... Calif. , Oct. 11, 2017  BioPharmX Corporation ... scientific team that developed an innovative way to use ... of the delivery of new drugs. ... Fall Clinical Dermatology Conference will show how researchers from ... Hospital, Harvard Medical School used a suite of imaging ...
(Date:10/11/2017)... 11, 2017  True Health, a leader in ... effort during National Breast Cancer Awareness month to ... Research recently ... that more than 10 million American women are ... BRCA1 or BRCA2 and have not had testing. These ...
(Date:10/10/2017)... ORANGE COUNTY, Calif. , Oct. 10, 2017  NDS received ... Mobile  — a medical-grade battery-powered display stand specifically designed for ... aims to transform technology into a clinical solution to support the ... costs. Innovative Design ... NDS ZeroWire Mobile Wireless Solution ...
Breaking Medicine Technology: