Navigation Links
Genetic Factors for Smoking Boost Chronic Bronchitis Risk
Date:2/29/2008

Swedish study says it's first to quantify heritability of the disease

FRIDAY, Feb. 29 (HealthDay News) -- While smoking is the leading risk factor for chronic bronchitis, genes also play a major role in the development of the disease, say Swedish researchers.

The study, which analyzed data on more than 40,000 twins born in 1958 or earlier, found that inherited genes accounted for 40 percent of the risk for chronic bronchitis and that 14 percent of the genetic risk was also linked to a genetic predisposition to smoke, whether or not a person actually smoked.

The findings are published in the first issue for March of the American Journal of Respiratory and Critical Care Medicine.

"(This) study on the population-based Swedish Twin Registry, showing a genetic effect for the development of chronic bronchitis that does not differ by sex, is the first to our knowledge to quantify heritability of the disease," Jenny Hallberg, of the department of public health sciences at Karolinska Institutet in Stockholm, said in a prepared statement.

Previous research had suggested that women were more likely than men to develop chronic bronchitis, so the findings that prevalence didn't differ by sex pointed to a number of intriguing possibilities, she noted.

"It is possible that women are more prone to report symptoms. Or, more likely, this could be an effect of smoking being more harmful for women due to their smaller lungs from start [exposure to cigarette smoke relative to body size]," Hallberg wrote.

The finding that genetic factors that contribute to chronic bronchitis are largely independent of smoking shouldn't be interpreted to mean that smoking has no effect on the disease, she cautioned.

"Although there was some genetic interplay, it is safe to say that smoking itself, and not the genes that predispose one to smoking, is a larger risk factor in developing chronic bronchitis of environmental exposures -- primarily smoking -- than genetic predisposition. This is true of both men and women," Hallberg wrote.

Chronic bronchitis and emphysema account for most cases of chronic obstructive pulmonary disease (COPD).

More information

The American Academy of Family Physicians has more about chronic bronchitis.



-- Robert Preidt



SOURCE: American Thoracic Society, news release, Feb. 29, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Genetic factors in smoking also increase risk of chronic bronchitis
2. Dr. Robert Leonard First in New England to Offer Genetic Test for Male Pattern Baldness
3. U of Minn researchers discover genetic cancer link between humans and dogs
4. New genetic association with schizophrenia found by researchers
5. Genetic mutation found in peripheral artery disease
6. Genetic town halls to be held in 5 US cities
7. DNA Findings Reveal Genetic History of Humans
8. Bone complications due to cystic fibrosis have a genetic cause, according to an MUHC study
9. New Genetic Technology IDs Virus That Killed Transplant Recipients
10. American Academy of Dermatology Research Confirms Genetic Skin Barrier Defect Linked to Eczema
11. Genetics Researcher at Childrens Hospital Selected as Howard Hughes Medical Institute Investigator
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Genetic Factors for Smoking Boost Chronic Bronchitis Risk
(Date:12/2/2016)... ... December 02, 2016 , ... On Dec. 2, 2016, CURE® magazine will ... Diego honoring the 2016 MPN Heroes—eight individuals who have made a difference in the ... beyond the standard of care, demonstrating leadership within the MPN community and/or a commitment ...
(Date:12/2/2016)... ... December 02, 2016 , ... More than 100 business, civic, ... to attend the UNCF Dothan-Wiregrass Mayor’s Luncheon Dec. 9, 2016. This inaugural event, ... and operating support to UNCF-member institutions, including Miles College, Oakwood University, Tuskegee University, ...
(Date:12/2/2016)... ... December 02, 2016 , ... ... launch of its 60-day free trial program for all of the company’s desktop ... offer a truly hassle free experience. , FlexiSpot’s unique desktop risers use an ...
(Date:12/2/2016)... ... 2016 , ... The annual time frame to change Medicare health and prescription ... December 7th. Currently-enrolled Medicare beneficiaries who are looking to switch from their current plan ... to make changes during this period order for their new policy to go into ...
(Date:12/2/2016)... ... December 02, 2016 , ... With the number of pain ... an injury, patients must find the one that works for them. When an inventor ... a machine that worked and decided to share it with others. , He developed ...
Breaking Medicine News(10 mins):
(Date:12/2/2016)... British Columbia , December 2, 2016 bioLytical ... bekannt gegeben, ab diesem Monat seinen  INSTI HIV-Selbsttests  in einer Version mit ... ... New: INSTI Self Test! ... , ,      (Photo: ...
(Date:12/2/2016)... The iShares Nasdaq Biotechnology Exchange-Traded Fund ... victory early in November. Less political risk has boosted ... predicting an uptick in M&A activities. Today, Stock-Callers.com takes ... they have fared at the last close: Celldex Therapeutics ... (NASDAQ: FOLD ), Navidea Biopharmaceuticals Inc. (NYSE ...
(Date:11/30/2016)... Nov 30, 2016 Research and ... Overview for Neuromodulation, Neurovascular, Neurosurgical and Monitoring Devices 2017 - ... ... The full report suite on the U.S. market ... drainage systems, intracranial pressure monitoring devices, detachable coils, liquid embolics, ...
Breaking Medicine Technology: