Navigation Links
Genes relate to level of alcohol consumption among Asians
Date:3/30/2011

In a study of 1,721 Korean male drinkers aged 40󈞱 y in an urban populationbased cohort, and another sample of 1,113 male drinkers from an independent rural cohort, information on average daily alcohol consumption was collected and DNA samples were collected for genotyping. In a genome-wide association (GWA) study, 12 single-nucleotide polymorphisms (SNPs) on chromosome 12q24 had genome-wide significant associations with alcohol consumption. These polymorphisms were closely related to genes that determine levels of ALDH, low levels of which relate to flushing after even small amounts of alcohol. Such enzymes are much more common among Asians than among westerners. Associations were tested only with the weekly amount of alcohol consumed, not the pattern of drinking; hence, these findings are not direct measures of alcoholism.

The editorial by Freedman et al states "epidemiologic literature suggests that those who begin drinking at an early age may be at greater risk for a maladaptive and more genetically pronounced form of alcohol consumption, and other environmental milieus affect the risk of alcoholism." It will be important to investigate the interplay of genes and environmental factors when seeking the determinants of alcohol abuse. Despite the findings of this study, our understanding of factors associated with alcoholism remains very limited.


'/>"/>

Contact: R. Curtis Ellison
ellison@bu.edu
508-333-1256
Boston University Medical Center
Source:Eurekalert

Page: 1

Related medicine news :

1. Genes Play Role in Prognosis With Non-Small Cell Lung Cancers
2. Researchers Who Discovered First Genes for Stuttering will Present Findings to the National Stuttering Association
3. Genes, environment, or chance?
4. UCLA study reveals how genes interact with their environment to cause disease
5. Long-Distance Runners May Have Endurance in Their Genes
6. Genes Behind Tooth Development Discovered
7. Smoking significantly increases risk of aneurysm in people with certain genes
8. Increasing neurogenesis might prevent drug addiction and relapse
9. Genetic Disease Foundation Encourages Americans to Know Their Genes at KnowYourGenes.org in Observance of World Rare Disease Day
10. Cluster of Genes Tied to Alcoholism
11. Cardiogenesis Reports Fourth Quarter and Full-Year 2009 Results
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/30/2014)... NY (PRWEB) August 30, 2014 ... throughout the planet has been one of the ... order to create a positive impact around the ... and staffed with top trained executives and trainers ... of people worldwide. Vital statistics demonstrate that ...
(Date:8/30/2014)... August 30, 2014 Market Research ... 2009-2019 is a professional and in-depth market survey ... report firstly reviews the basic information of Cell ... The report then explores global and China’s top ... capacity, Production value, and market share etc. The ...
(Date:8/30/2014)... 30, 2014 Insomnia causes disturbances in every ... how they unknowingly developed insomnia and the steps often used ... Tune in to the show at this link: ... live on August 30, and will be podcasted at ... go to DrCarolFrancisTalkRadio.com. , "Insomnia causes countless unrecognized ...
(Date:8/30/2014)... 2014 In today’s world, a good night’s ... Snoring and sleep apnea (a medical problem where the airway ... bed partners of the rest they need to face their ... snores and 20 million people in the United States alone ... and treated; and of those treated, many cannot tolerate their ...
(Date:8/30/2014)... Administration of colchicine, a plant-based medication commonly used ... showed mixed results in reducing potential complications from ... the risk of gastrointestinal adverse effects, according to ... study is being released early online to coincide ... Cardiology Congress. , Common complications after cardiac surgery ...
Breaking Medicine News(10 mins):Health News:Cradle of Aviation Museum Opens Its Doors to Long Island Scientologists 2Health News:Cell Disruptor Industry Global and Chinese Analysis for 2009-2019 in New Research Report at ReportsnReports.com 2Health News:Cell Disruptor Industry Global and Chinese Analysis for 2009-2019 in New Research Report at ReportsnReports.com 3Health News:Cell Disruptor Industry Global and Chinese Analysis for 2009-2019 in New Research Report at ReportsnReports.com 4Health News:Sleepless Nights, Exhausting Days, Mental Fog – Relief for Insomnia With Clinical Psychologist Dr. Carol Francis 2Health News:Snoring: Bad for Relationships, Bad for Health 2Health News:Snoring: Bad for Relationships, Bad for Health 3Health News:Medication shows mixed results in reducing complications from cardiac surgery 2
... deaths every year, even though it has been known for ... reduces the chance of being bitten by the mosquitoes which ... how best to increase the use of such nets, particularly ... in the latest issue of PLoS Medicine, has shown that ...
... (hypertension) is associated with an increased risk of heart ... known as NSAIDs, for example to treat individuals with ... hypertension is not clear because they inhibit the generation ... affect blood pressure and the effects of inhibiting the ...
... Md. Scientists have shown that recently developed mouse ... may not be as effective as previously assumed. Sascha ... lead author Eva Czirr, Ph.D. student at the University ... 24 issue of the Journal of Biological Chemistry ...
... irradiation after chemotherapy significantly reduces the risk of ... lung cancer (SCLC), according to the results of ... published in the New England Journal of Medicine ... an aggressive tumor that constitutes nearly 15% of ...
... has revealed a breakdown in normal patterns of emotional ... depression to suppress negative emotional states. Efforts by depressed ... images enhanced activity in several brain areas, including the ... according to a report in the August 15 issue ...
... team of Mayo Clinic researchers has discovered a new, ... joints, potentially leading to better treatment options and patient ... adhere to the prosthetic surface, was tested in a ... joints who were having their prosthetic joints removed for ...
Cached Medicine News:Health News:Free distribution of insecticide-treated mosquito nets can save lives 2Health News:Effectiveness of mouse breeds that mimic Alzheimer's disease symptoms questioned 2Health News:Effectiveness of mouse breeds that mimic Alzheimer's disease symptoms questioned 3Health News:Prophylactic cranial irradiation in small cell lung cancer significantly increases survival 2Health News:Prophylactic cranial irradiation in small cell lung cancer significantly increases survival 3Health News:Brain imaging reveals breakdown of normal emotional processing 2Health News:Mayo Clinic researchers discover new diagnostic test for detecting infection in prosthetic joints 2Health News:Mayo Clinic researchers discover new diagnostic test for detecting infection in prosthetic joints 3
(Date:8/29/2014)... Aug. 29, 2014 Research and Markets ... and Development Trend Forecast of Pharmaceutical Equipment Market in ... Research and Development Trend Forecast of Pharmaceutical Equipment ... analyzes China,s pharmaceutical equipment industry ... demand, competition landscape, and business performance of domestic major ...
(Date:8/29/2014)... Diseases largely eradicated in the United States ... declared eliminated in 2000, yet the CDC reports 593 ... incidence in 20 years. In July, California,s ... problem of "epidemic proportions." Across ... preventable diseases—in part because some parents (more than 10 ...
(Date:8/29/2014)... Ohio , Aug. 29, 2014  In ... how to leverage a hospital pharmacy as a strategic ... and national practice leader for Cardinal Health,s Innovation Delivery ... pharmacy care can benefit both hospitals and patients. ... is only one part of their job in a ...
Breaking Medicine Technology:Research and Development Trend Forecast of Pharmaceutical Equipment Market in China, 2014-2018 2Vaccines at the Crossroads: Outbreaks On the Rise Across America 2Vaccines at the Crossroads: Outbreaks On the Rise Across America 3Five Ways Hospital Pharmacies Can Fulfill Their Quality Care Mission 2Five Ways Hospital Pharmacies Can Fulfill Their Quality Care Mission 3Five Ways Hospital Pharmacies Can Fulfill Their Quality Care Mission 4
... GeneXpert(R) System ... ... today announced the U.S. Food & Drug Administration (FDA) categorized,Cepheid,s ... Clinical Laboratory Improvement Amendments (CLIA).,The new test is designed for ...
... Michael J. Fox,Foundation today announced the availability of ... toward transformative treatments and a cure for,Parkinson,s disease., ... researchers through the,Foundation,s Pipeline Programs, five separate initiatives ... drug development pipeline. This includes,early-stage discovery research, translational ...
Cached Medicine Technology:Cepheid Molecular Diagnostic Test for Positive Blood Culture Bottles Categorized 'Moderate Complexity' by FDA 2Cepheid Molecular Diagnostic Test for Positive Blood Culture Bottles Categorized 'Moderate Complexity' by FDA 3Cepheid Molecular Diagnostic Test for Positive Blood Culture Bottles Categorized 'Moderate Complexity' by FDA 4Michael J. Fox Foundation Announces $11 Million in 2009 Funding for Translational, Pre-Clinical and Clinical Parkinson's Disease Research 2Michael J. Fox Foundation Announces $11 Million in 2009 Funding for Translational, Pre-Clinical and Clinical Parkinson's Disease Research 3Michael J. Fox Foundation Announces $11 Million in 2009 Funding for Translational, Pre-Clinical and Clinical Parkinson's Disease Research 4
Steel Knife with box for the Series 8000 Sliding Microtome. C-Profile, 240 x 33 x13m, 22 Degree angle, tapped to accept holder for Shandon knife sharpener....
... M3500 Radial Microtome has a look that is ... range of functions and capabilities that will please ... years of experience and knowledge but still breaking ... M3500 Microtome will be the answer to many ...
Clock oil, 6 grams net...
Coarse abrasive for knife sharpening, 6 grams net...
Medicine Products: