Navigation Links
Genes behind increasingly common form of cancer identified
Date:10/13/2009

Researchers at the University of Gothenburg, Sweden, have identified two genes believed to play a role in the development of endometrial cancer. These results may eventually lead to better diagnosis and treatment of this increasingly common form of cancer.

Endometrial cancer, also known as uterine or womb cancer, is the most common malignant cancer of the female reproductive system in the Western World. The number of cases being detected has increased markedly, as has mortality. Around 1 300 women in Sweden are diagnosed with endometrial cancer each year, equivalent to 6 per cent of all cases of cancer in women.

Genes identified

Cancer is caused by genetic changes - mutations - in cells' DNA disrupting the normal regulation of growth. In her study, researcher Carola Hedberg from the Department of Cell and Molecular Biology at the University of Gothenburg has identified the genes involved in the development of endometrial cancer.

Rat models

Her research focuses on genetic analyses of rats, and more specifically their chromosome 10. This chromosome is interesting because it is prone to deletion - the loss of genetic material - in connection with tumour formation. Hedberg has been able to show that one or more growth-suppressing genes are normally to be found in the middle of the chromosome where this loss of genetic material is greatest. The deletion of these genes eliminates their growth-regulating functions, and this is believed to contribute to the development of endometrial cancer.

New treatment

Information about specific genetic changes in rats as a model can be transposed to the equivalent form of cancer in humans. A knowledge of the genes involved in a particular form of cancer may therefore contribute to cancer care in the longer term through better diagnostic tools and new forms of treatment and preventive care. In more in-depth studies, Hedberg and her colleagues have identified two particular genes, Skip and Myo1c, which are believed to play a key role in the development of endometrial cancer.


'/>"/>

Contact: Krister Svahn
krister.svahn@science.gu.se
46-317-864-912
University of Gothenburg
Source:Eurekalert

Related medicine news :

1. Genes signal late-stage laryngeal cancer, poorer outcome
2. Researchers identify genes associated with onset age of Parkinsons disease
3. SAGE launches Genes & Cancer
4. Lung cancer risk increases with expression of specific genes
5. Cardiogenesis Announces Successful Symposium at the Transcatheter Cardiovascular Therapeutics (TCT) Meeting
6. Two Genes May Determine How Well MS Patients Do
7. Mayo Clinic identifies 2 genes as potential therapeutic targets for multiple sclerosis
8. ThermoGenesis Corp. to Announce Fourth Quarter and Year End Results on September 9
9. Benji, Marley or Bo: Three Genes Dictate Dogs Coat
10. Sixteen Genesis HealthCare Centers Receive Prestigious Award for Continuous Quality Improvement in Long Term Care
11. Cardiogenesis Reports Second Quarter 2009 Results
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/22/2017)... , ... August 22, 2017 , ... ... Anti-Aging Medicine recently spoke at a popular international aesthetics conference for medical professionals ... on restoring his patients’ health and his growing practice. , Dr. George ...
(Date:8/22/2017)... ... 22, 2017 , ... Nurses at Apple Rehab Watch Hill , a ... training and certification in Closed Pulse Irrigation™ (CPI) for wound care. This ... the Centers for Medicare and Medicaid Services, to have a CPI machine that will ...
(Date:8/22/2017)... ... August 22, 2017 , ... “Without Love’s Beauty and ... and the struggles faced while hoping for a better life. “Without Love’s Beauty ... Von Bernewitz, who spent 13 years working with deprived/neglected adolescents and almost 20 ...
(Date:8/22/2017)... (PRWEB) , ... August 22, 2017 , ... TopConsumerReviews.com recently ... to fight Fatigue . , As the stress of modern life continually makes ... the pace. Constant use of artificial stimulants can trap people in vicious high/low cycles ...
(Date:8/21/2017)... , ... August 22, 2017 , ... ... not without risk to health and safety. By learning and implementing best practices ... , In this webinar, attendees will gain a better understanding of a ...
Breaking Medicine News(10 mins):
(Date:8/2/2017)...  Life Flight Network and PeaceHealth Oregon Network announced they ... and operational efficiency for patients at hospitals in ... Cottage Grove , and Florence, Oregon ... Flight Network work collaboratively to move patients who require the ... time sensitive emergency exists. ...
(Date:7/31/2017)... Pharmacy, Inc. (NYSE: DPLO), has been named one of the ... Crain,s Detroit Business . The annual Crain,s Fast ... growth. This year,s edition measures growth from 2013 to 2016. ... list, visit crainsdetroit.com/awards/fast_50/2017 .  "Being named ... Phil Hagerman , CEO and chairman of Diplomat. "We,ve made ...
(Date:7/28/2017)... July 28, 2017 Hill-Rom Holdings, Inc. ("Hill-Rom") ... third quarter ended June 30, 2017, and updated its ... For the fiscal third quarter, Hill-Rom ... $0.68 per diluted share in the prior-year period. These ... $0.39 per diluted share primarily related to the non-cash ...
Breaking Medicine Technology: