Navigation Links
Genes behind increasingly common form of cancer identified
Date:10/13/2009

Researchers at the University of Gothenburg, Sweden, have identified two genes believed to play a role in the development of endometrial cancer. These results may eventually lead to better diagnosis and treatment of this increasingly common form of cancer.

Endometrial cancer, also known as uterine or womb cancer, is the most common malignant cancer of the female reproductive system in the Western World. The number of cases being detected has increased markedly, as has mortality. Around 1 300 women in Sweden are diagnosed with endometrial cancer each year, equivalent to 6 per cent of all cases of cancer in women.

Genes identified

Cancer is caused by genetic changes - mutations - in cells' DNA disrupting the normal regulation of growth. In her study, researcher Carola Hedberg from the Department of Cell and Molecular Biology at the University of Gothenburg has identified the genes involved in the development of endometrial cancer.

Rat models

Her research focuses on genetic analyses of rats, and more specifically their chromosome 10. This chromosome is interesting because it is prone to deletion - the loss of genetic material - in connection with tumour formation. Hedberg has been able to show that one or more growth-suppressing genes are normally to be found in the middle of the chromosome where this loss of genetic material is greatest. The deletion of these genes eliminates their growth-regulating functions, and this is believed to contribute to the development of endometrial cancer.

New treatment

Information about specific genetic changes in rats as a model can be transposed to the equivalent form of cancer in humans. A knowledge of the genes involved in a particular form of cancer may therefore contribute to cancer care in the longer term through better diagnostic tools and new forms of treatment and preventive care. In more in-depth studies, Hedberg and her colleagues have identified two particular genes, Skip and Myo1c, which are believed to play a key role in the development of endometrial cancer.


'/>"/>

Contact: Krister Svahn
krister.svahn@science.gu.se
46-317-864-912
University of Gothenburg
Source:Eurekalert

Related medicine news :

1. Genes signal late-stage laryngeal cancer, poorer outcome
2. Researchers identify genes associated with onset age of Parkinsons disease
3. SAGE launches Genes & Cancer
4. Lung cancer risk increases with expression of specific genes
5. Cardiogenesis Announces Successful Symposium at the Transcatheter Cardiovascular Therapeutics (TCT) Meeting
6. Two Genes May Determine How Well MS Patients Do
7. Mayo Clinic identifies 2 genes as potential therapeutic targets for multiple sclerosis
8. ThermoGenesis Corp. to Announce Fourth Quarter and Year End Results on September 9
9. Benji, Marley or Bo: Three Genes Dictate Dogs Coat
10. Sixteen Genesis HealthCare Centers Receive Prestigious Award for Continuous Quality Improvement in Long Term Care
11. Cardiogenesis Reports Second Quarter 2009 Results
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/24/2017)... , ... April 24, 2017 , ... ... laboratory-grade deionized water from the same place. From 101 Water Texas, here are ... Patients and staff can enjoy a continuous supply of pure, fresh, oxygenated water, ...
(Date:4/22/2017)... ... April 22, 2017 , ... PharmacyChecker.com released its first International ... of 70% when buying medication online from Canadian pharmacies verified in the PharmacyChecker ... other countries. The report (chart below) compares U.S. and foreign prices for 20 ...
(Date:4/21/2017)... ... 21, 2017 , ... The staff at Palm Beach Face is proud to announce that their ... London Marathon. Set to take place on April 23rd, the London Marathon has a long ... run as part of team EMPOWER, raising money for the international charity, Smile Train. ...
(Date:4/21/2017)... , ... April 21, 2017 , ... ... Allegheny County that offers services to communities throughout the greater Pittsburgh metropolitan region, ... charity drive to provide adaptive bicycles for differently-abled children. , Variety the Children’s ...
(Date:4/21/2017)... Kong (PRWEB) , ... April 21, 2017 , ... The ... (U3DP), the first 3D printing facility among higher education institutions in Hong Kong to ... printing, in terms of the range and quantity of facilities in Hong Kong. ...
Breaking Medicine News(10 mins):
(Date:4/20/2017)... Research and Markets has announced the addition of the "Global ... and Increasing Usage of Complex Biologics during the Forecast Period" ... The ... Billion in 2015 to around USD 26 Billion by 2020. ... Rapidly Expanding Injectables Market and Increasing Usage of Complex Biologics during ...
(Date:4/20/2017)... 2017 Eyevensys, a private biotechnology ... gene expression technology that enables the safe, local, sustained ... a wide range of ophthalmic diseases, announces it has ... Regulatory Agency (MHRA) to advance its technology into clinical ... The ...
(Date:4/19/2017)... NEW YORK , April 19, 2017 The ... anticipated to showcase a healthy CAGR during the forecast period ... product type in the global digital mobile X-Ray devices market, ... 2,000 Mn in 2017, expanding at a CAGR of 7% ... create absolute $ opportunity of more than US$ 100 Mn ...
Breaking Medicine Technology: