Navigation Links
Genes That Control Body's Salt Levels Are Identified
Date:2/16/2009

Whether finding will lead to treatment improvements remains unclear

MONDAY, Feb. 16 (HealthDay News) -- The largest study of the effects of genetics on blood pressure in humans has linked variant versions of genes that control levels of salt in the body with high blood pressure, a major risk factor for heart disease and stroke.

"There have been hundreds of genes and gene variants reported to be related to blood pressure," said Dr. Christopher Newton-Cheh, assistant professor of medicine at Harvard Medical School and the Center for Human Genetic Research at Massachusetts General Hospital and lead author of a report in Nature Genetics. "What distinguishes this study is the ability to genotype 30,000 people to establish a relationship that these gene variants cause higher levels of natriuretic peptides and therefore are related to blood pressure." Natriuretic peptides are compounds that help the body get rid of salt.

It's not yet clear that the finding will be of use in medical practice, Newton-Cheh said. Drugs aimed at the genes might be no more effective at keeping high blood pressure under control than existing medications, such as diuretics, he said. But the study does offer valuable insight into a basic physiological cause of high blood pressure.

The researchers looked at variants of two genes for these peptides -- atrial natriuretic peptide (ANP) and B-type natriuretic peptide (BNP). They found three variants clearly related to higher levels of the peptides and, therefore, to lower blood pressure. Higher peptide levels lead to lower blood pressure because "these are molecules designed to let the body get rid of salt and relax blood vessels," Newton-Cheh explained.

"What's exciting about this study is that it proves that in human beings, natriuretic peptides are important in blood pressure," he said. "Until now, the finding has been limited to animals -- that if you take away the ANP gene in mic
'/>"/>

Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. Empathy Might Be in the Genes
2. Genes Help Cancer-Linked Viruses Elude Immune System
3. 2 Genes Implicated in Autism
4. Genesis Successfully Defends Multi-Million Dollar Arbitration Filed by CRG and CRGP; Related Parties Withdraw Remaining Demands for Arbitration Against Genesis
5. Genesis Pharmaceuticals Successfully Defends Itself in a Multi-Million Dollar Arbitration, Two Other Arbitration Proceedings Against Genesis are Withdrawn
6. New genes involved in acute lymphoblastic leukemia play fundamental role in prognosis of the disease
7. Angiogenesis linked to poor survival in patients with rare type of ovarian cancer
8. Penn study finds link between Parkinsons disease genes and manganese poisoning
9. Genesis Pharmaceuticals Enters Into Agreement to Purchase Hongrui Pharmaceuticals, and Acquire 22 New Traditional Chinese Medicines
10. Cardiogenesis Announces Successful Educational Symposium at Society of Thoracic Surgeons Meeting in San Francisco
11. In Kids, Genes May Affect Leukemia Treatment
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Genes That Control Body's Salt Levels Are Identified
(Date:12/25/2014)... 2014 “ SmileStix ” was featured on ... latest and coolest mobile applications on the iOS, Android, and ... of NewsWatch, conducted the app review and shared with viewers ... stickers. , The old saying goes, “A picture says a ... that can describe a single image, because each picture holds ...
(Date:12/24/2014)... AlignLife of Wauwatosa loves helping those ... During the holiday season, AlignLife looks forward to their annual ... Dr. Sara Mahalko-Leonhardt, owner of AlignLife. "It brings our patients ... we are able to give kids toys for Christmas who ... the generosity of our patients." , The 70 toys were ...
(Date:12/24/2014)... New York, New York (PRWEB) December 24, 2014 ... continue to mount in a mass tort litigation currently ... Liebhard LLP reports. As of December 24, 2014, ... in the proceeding on behalf of individuals who developed ... to its use. Data from the Court indicates that ...
(Date:12/24/2014)... December 25, 2014 Today, Yunx.co.uk, a ... evening dresses and other special occasion outfits, unveils ... models are offered at discounted prices, up to 80% ... young ladies with their fashionable designs, gorgeous looks and ... exception. The business is devoted to designing and offering ...
(Date:12/24/2014)... holidays can be a challenge for people who suffer migraines, ... "This is the season in which many people overindulge ... Dodick, chair of the American Migraine Foundation, said in a ... through food and beverage choices, to help reduce the risk ... neurology at the Mayo Clinic in Scottsdale, Ariz. , , ...
Breaking Medicine News(10 mins):Health News:An Application to Create Custom Stickers was Featured on NewsWatch Television on December 19, 2014 2Health News:AlignLife of Wauwatosa Brings Joy to Less Fortunate Families 2Health News:Risperdal Lawsuits Continue to Climb, as Claims in Pennsylvania Litigation Exceed 1,180 Filings, Bernstein Liebhard LLP Reports 2Health News:Risperdal Lawsuits Continue to Climb, as Claims in Pennsylvania Litigation Exceed 1,180 Filings, Bernstein Liebhard LLP Reports 3Health News:Risperdal Lawsuits Continue to Climb, as Claims in Pennsylvania Litigation Exceed 1,180 Filings, Bernstein Liebhard LLP Reports 4Health News:Yunx.co.uk Unveils 65 New Bridesmaid Dresses for the UK market 2Health News:Expert Offers Tips for Preventing Holiday Migraines 2
... Board: NZYM) today announced financial results for its fiscal fourth quarter ... , For the fourth quarter ended March 31, 2009, revenue ... for the same period last year. Gross income for the ... million for the same period last year. Operating income for ...
... , June 3 IMAGINE Software, ... its newest features implemented within the IMAGINEradiology(TM) practice management ... 19-21. , , The ... that allows for easy deployment and maintenance distribution through ...
... Calif., June 3 Ambry Genetics is pleased to ... offering the Ambry CMA: 105K Oligo Array, which is ... genetic disorders. In a partnership with Baylor ... provide one of the most comprehensive, clinically-validated genetic tests ...
... Year-Old USAID/State Department/Private Sector Initiative Unveils Initial Aid ... Chiles and CAFAmerica,s Saxon-Harrold Report on Progress. ... One Woman Initiative ( http://www.OneWomanInitiative.org ), a one-year-old ... significant Muslim populations, today announced its first grants, ...
... An innovative University of Georgia graduate program in ... to work with elementary-age students with autism over the ... federal grant to train teachers to work with similarly ... disability that is part of a group known as ...
... blood cells to injury site, research shows , WEDNESDAY, ... to prevent infection in cuts and scrapes -- also may ... , U.S. researchers have discovered that when the tail fins ... is released from the wound and into the surrounding tissue. ...
Cached Medicine News:Health News:Synthetech Announces Fiscal 2009 Results 2Health News:Synthetech Announces Fiscal 2009 Results 3Health News:Synthetech Announces Fiscal 2009 Results 4Health News:Synthetech Announces Fiscal 2009 Results 5Health News:Synthetech Announces Fiscal 2009 Results 6Health News:IMAGINE Software Unveils Advanced IMAGINEradiology(TM) Features 2Health News:'Ambry Genetics Announces Launch of Chromosomal Microarray to Offer Whole Genome Analysis' 2Health News:'Ambry Genetics Announces Launch of Chromosomal Microarray to Offer Whole Genome Analysis' 3Health News:'One Woman Initiative' Announces First Grants to Women's Organizations in Five Nations 2Health News:'One Woman Initiative' Announces First Grants to Women's Organizations in Five Nations 3Health News:'One Woman Initiative' Announces First Grants to Women's Organizations in Five Nations 4Health News:UGA grad program expands to prepare teachers to work with secondary students with autism 2Health News:UGA grad program expands to prepare teachers to work with secondary students with autism 3Health News:Key to Wound-Healing May Be Explained in Fish Tail 2
(Date:12/24/2014)... , December 24, 2014 ... Report on Global Disposable Syringe Industry of ... its online business intelligence library. ... Disposable Syringe Industry is a professional and ... market.  For overview analysis, the report introduces ...
(Date:12/24/2014)... ALEXANDRIA, Va. , Dec. 23, 2014 /PRNewswire-USNewswire/ ... stringent diastolic blood pressure target for people with ... either moderate or high doses of statins, in ... risk management enacted by the American College of ... recommendations are reflected in the most recent changes ...
(Date:12/24/2014)... , Dec. 23, 2014  Medical Science Liaisons ... the key link between the medical device industry and ... more in the coming years as the device industry ... According to research by benchmarking firm, Best Practices, ... gain an important edge is by harnessing new technology ...
Breaking Medicine Technology:World Disposable Syringe Market 2014 Report: China and Regional Analysis 2World Disposable Syringe Market 2014 Report: China and Regional Analysis 3World Disposable Syringe Market 2014 Report: China and Regional Analysis 4World Disposable Syringe Market 2014 Report: China and Regional Analysis 5New Standards of Care Provide Guidelines for Statin Use for People with Diabetes to Prevent Heart Disease 2New Standards of Care Provide Guidelines for Statin Use for People with Diabetes to Prevent Heart Disease 3New Standards of Care Provide Guidelines for Statin Use for People with Diabetes to Prevent Heart Disease 4Role of Medical Science Liaisons Evolving in Medical Device Sector 2
... Compressor provides effective therapy at an affordable price. ... home or on the go and features ease ... reliable operation you have come to count on ... the perfect solution for those patients seeking a ...
... delivery is an important part of managing ... and convenient products mean delivering the aerosolized ... time while minimizing medication waste. Aerosol delivery ... line of Nebulizers, including the new NebuTech® ...
... SynergyPlus+ is recommended for people with low ... limbs associated with failed back syndrome, low ... people with post laminectomy pain, multiple back ... disease and Complex Regional Pain Syndrome (CRPS). ...
Whether you require high flow rates for critical situations or lower rates for others, this insufflator handles both situations equally well, regulated by the preselected pressure....
Medicine Products: