Navigation Links
Genes Play Part in Prostate Cancer Among Races
Date:5/15/2008

Whites at higher risk than Hispanics, but genetics determines who gets it

THURSDAY, May 15 (HealthDay News) -- Genetic differences may explain why white men have a higher prostate cancer risk than Hispanic men, information which may help doctors identify men who are more likely to develop the disease, U.S. researchers say.

They collected blood samples from 932 white men and 414 Hispanic men from south Texas and looked for mutations from the nuclear vitamin D receptor (CDX2 and FokI), which modulates the actions of vitamin D, and from 5-reductase type II (V89L & A49T), which converts testosterone to dihydrotestosterone, a more potent form of the male hormone.

Among non-Hispanic white men with V89L, FokI was associated with a more than a 50 percent increased risk of prostate cancer. This effect was not seen in Hispanic men. Among Hispanic white men, a combination of CDX2 and V89L was associated with a more than threefold increased risk of prostate cancer. This link was not seen in white men.

The findings, published in the May 15 issue of Clinical Cancer Research, provide new information about genetic risks and racial differences, but need to be confirmed in larger studies.

"Prostate cancer is not likely caused by a few genes, but by multiple genes from different pathways. This study illustrates the importance of examining multiple genes to understand genetic risks for prostate cancer and differences seen by ethnicity," study author Kathleen Torkko, an instructor in the department of pathology at the University of Colorado, Denver, said in a prepared statement.

"Going forward, we need not only a better understanding of genetics but a better understanding of race and ethnicity. Studying disease by race is a complex issue, and the public needs to understand that we are trying to raise biological, rather than social, questions," Torkko said.

She said the goal of this research is
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved

Page: 1 2

Related medicine news :

1. Connecting cancer genes
2. Cardiogenesis Reports First Quarter 2008 Results
3. Effect of mutant p53 stability on tumorigenesis and drug design
4. Hoffa, Cherry to Speak at Community Rally Supporting Genesys Nurses
5. Bread mold may hold secret to eliminating disease-causing genes
6. Unraveling the Link Between Genes and Environment
7. Cardiogenesis Corporation to Report 2008 First Quarter Results on May 15th
8. Genes Linked to Osteoporosis Identified
9. Environment key early: Genes role expands in alcohol dependence
10. A stem cell type supposed to be crucial for angiogenesis and cancer growth does not exist?
11. Breast cancer risk amplified by additional genes in combo with BRCA mutation
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/21/2014)... The International and American Associations for Dental Research (IADR/AADR) ... Prevalence Following Five Decades of Decline." This study, by ... Chapel Hill, USA, follows edentulism (tooth loss) over the ... losing teeth and requiring dentures. It is published in ... Dental Research ( JDR ). , The ...
(Date:8/21/2014)... United Benefit Advisors (UBA), the ... pleased to announce Trinity Benefit Advisors as its ... Trinity Benefit Advisors is a full service firm ... clients. Their consultative approach is comprised of four ... and monitoring. Their dedication to effective results and ...
(Date:8/21/2014)... York (PRWEB) August 21, 2014 According ... Research "Enteral Feeding Devices Market (Enteral Feeding Tubes, Enteral ... - Global Industry Analysis, Size, Share, Growth, Trends and ... was valued at USD 2.0 billion in 2012 and ... 3.1 billion in 2019growing at a CAGR of 6.2% ...
(Date:8/21/2014)... authorities need to ensure that experimental drugs to treat ... randomized controlled trials, according to a new Viewpoint, published ... 2014]. , Leading bioethicists Professor Ezekiel Emanuel, ... Annette Rid, of King,s College London, UK, outline critical ... experimental drugs are to be deployed in the Ebola ...
(Date:8/21/2014)... Albany, NY (PRWEB) August 21, 2014 ... 2020 - Novel Therapeutic Approaches Target High Unmet ... provides in-depth analysis of the Glioblastoma Multiforme (GBM) ... Australia, China, India and Japan. The report provides ... market forecasts until 2020. It also covers disease ...
Breaking Medicine News(10 mins):Health News:Study shows steep decline in tooth loss, increase in socioeconomic disparities 2Health News:Trinity Benefit Advisors is the Latest Firm to Join United Benefit Advisors 2Health News:Trinity Benefit Advisors is the Latest Firm to Join United Benefit Advisors 3Health News:Enteral Feeding Devices Market: Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2013 - 2019 2Health News:Enteral Feeding Devices Market: Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2013 - 2019 3Health News:Enteral Feeding Devices Market: Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2013 - 2019 4Health News:The Lancet: Experimental Ebola drugs must be fairly distributed and tested ethically in clinical trials 2Health News:Asia-Pacific Glioblastoma Multiforme (GBM) Market Size Industry Analysis, Share, Growth, Trends and Forecast to 2020: MarketResearchReports.biz 2Health News:Asia-Pacific Glioblastoma Multiforme (GBM) Market Size Industry Analysis, Share, Growth, Trends and Forecast to 2020: MarketResearchReports.biz 3Health News:Asia-Pacific Glioblastoma Multiforme (GBM) Market Size Industry Analysis, Share, Growth, Trends and Forecast to 2020: MarketResearchReports.biz 4Health News:Asia-Pacific Glioblastoma Multiforme (GBM) Market Size Industry Analysis, Share, Growth, Trends and Forecast to 2020: MarketResearchReports.biz 5Health News:Asia-Pacific Glioblastoma Multiforme (GBM) Market Size Industry Analysis, Share, Growth, Trends and Forecast to 2020: MarketResearchReports.biz 6Health News:Asia-Pacific Glioblastoma Multiforme (GBM) Market Size Industry Analysis, Share, Growth, Trends and Forecast to 2020: MarketResearchReports.biz 7
... Healthcare Access for All , , WASHINGTON, June ... Foundation (PAF) -- a national non-profit organization that seeks ... care, maintenance of employment and preservation of their financial ... debilitating diseases -- are in Washington, D.C. this week ...
... Inc., a developer of innovative therapies in women,s health, ... Coast Service Options, Inc. ("First Coast"), a large regional ... Puerto Rico and the U.S. Virgin Islands, has removed ... incontinence (SUI) from its noncovered services list and will ...
... /PRNewswire-FirstCall/ - AlphaRx Inc. (OTCBB: ALRX) releases letter to their shareholders: ... take a few minutes to update the current views on AlphaRx. ... last quarter with a small profit. Aside from the fact that ... one front. The events that occurred over the past few weeks, ...
... SignatureForum, a leading online source for consumer reviews ... the highest-rated cosmetic surgeons of the past year. The ... Providers group announced last month, is developed by processing ... United States and Canada. Rated on an overall scale ...
... to Treat Diseases (HTDS.PK) www.htdsmedical.com - announced ... recovering intellectual property (IP) rights that could provide an ... retained a USA based IP consultant to attempt to ... shareholder and its corporate advisors, verily believe was inappropriately ...
... YORK, June 24 Many Americans feel that today,s healthcare ... insurance premiums have made it more difficult to afford health ... resolution expert and physical therapist Mitchell Yass, is whether the ... believes they are not -- and what healthcare segment seems ...
Cached Medicine News:Health News:Patient Advocates From All 50 States Gather in Nation's Capitol to Meet With Lawmakers and Urge Passage of Comprehensive Health Care Reform 2Health News:First Coast Medicare to Provide Case by Case Reimbursement for the Renessa(R) Treatment for Incontinence in Women 2Health News:First Coast Medicare to Provide Case by Case Reimbursement for the Renessa(R) Treatment for Incontinence in Women 3Health News:AlphaRx Shareholder Update 2Health News:SignatureForum Reveals Top-Rated Cosmetic Surgeons in US 2Health News:Hard To Treat Diseases (HTDS.PK) To Regain Intellectual Property (IP) Ownership 2Health News:Hard To Treat Diseases (HTDS.PK) To Regain Intellectual Property (IP) Ownership 3Health News:One Man's Mission to Improve Our Healthcare System and Resolve Chronic Pain 2
(Date:8/21/2014)... 2014  Zacks.com announces the list of stocks featured in ... discuss the latest news and events impacting stocks and the ... (NYSE: HPQ - Free Report ), IBM (NYSE: ... SB - Free Report ), GlaxoSmithKline plc (NYSE: GSK ... FI - Free Report ). Today, Zacks is ...
(Date:8/21/2014)... , Aug. 21, 2014  Armada Health Care ... organization (GPO), is pleased to announce an agreement ... a host of innovative specialty pharmacy patient program ... enhanced therapy management services to specialty patients via ... Aurora will use the OTM platform ...
(Date:8/21/2014)... , Aug. 21, 2014 /CNW/ - Bedrocan Cannabis Corp., ... independent members to its Board of Directors, enhancing ... of the company, a leading licensed producer of ... Internationally, Bedrocan has 13 years, experience in producing ... seven countries, including Canada. As ...
Breaking Medicine Technology:The Zacks Analyst Blog Highlights: Hewlett-Packard, IBM, Safe Bulkers, GlaxoSmithKline and Frank's International 2The Zacks Analyst Blog Highlights: Hewlett-Packard, IBM, Safe Bulkers, GlaxoSmithKline and Frank's International 3The Zacks Analyst Blog Highlights: Hewlett-Packard, IBM, Safe Bulkers, GlaxoSmithKline and Frank's International 4The Zacks Analyst Blog Highlights: Hewlett-Packard, IBM, Safe Bulkers, GlaxoSmithKline and Frank's International 5The Zacks Analyst Blog Highlights: Hewlett-Packard, IBM, Safe Bulkers, GlaxoSmithKline and Frank's International 6The Zacks Analyst Blog Highlights: Hewlett-Packard, IBM, Safe Bulkers, GlaxoSmithKline and Frank's International 7The Zacks Analyst Blog Highlights: Hewlett-Packard, IBM, Safe Bulkers, GlaxoSmithKline and Frank's International 8The Zacks Analyst Blog Highlights: Hewlett-Packard, IBM, Safe Bulkers, GlaxoSmithKline and Frank's International 9The Zacks Analyst Blog Highlights: Hewlett-Packard, IBM, Safe Bulkers, GlaxoSmithKline and Frank's International 10The Zacks Analyst Blog Highlights: Hewlett-Packard, IBM, Safe Bulkers, GlaxoSmithKline and Frank's International 11Aurora Health Care Partners with Armada Health Care to Deliver Added Pharmacy Capabilities to Specialty Patients 2Aurora Health Care Partners with Armada Health Care to Deliver Added Pharmacy Capabilities to Specialty Patients 3Senior Life Sciences Executives Join Bedrocan as Independent Directors 2Senior Life Sciences Executives Join Bedrocan as Independent Directors 3
... manufacturer of ergonomic laboratory equipment, has partnered with ... Laboratory Centrifuges to North and Latin America. ... and manufacturing of laboratory centrifuges, Awel holds exclusive patented ... with an emphasis on ergonomics. (Photo: ...
... Calif., March 27, 2012 Jacobs Engineering Group Inc. ... of its projects received Facility of the Year Awards ... INTERPHEX and Pharmaceutical Processing magazine, sponsors of the awards ... Program of Projects at the Merck facility in Durham, ...
Cached Medicine Technology:NuAire Introduces Awel Centrifuges to North and Latin America 2Jacobs' Projects Selected "Facility of the Year Award" Winners 2
... camera systems for optimum image quality ... digital camera system records live cells, ... fast exposure times at the lowest ... the visible spectrum assure reliable results ...
... U-III's compact, sleek design and ... sensor, make it the system ... applications including FISH. It is ... institutes and universities and wherever ...
Coolpix 5000 microscope package includes Coolpix 5000 digital camera, MDC-A relay lens, EH52 AC adapter, UR-E6 step-down adapter ring, EU-1 wired remote control unit....
Semi-Automated Chemistry Analyzer with model screen master. The Screen Master incorporates many powerful features in one compact unit. Useful for biochemical investigations, enzymatic, immunoturbidi...
Medicine Products: