Navigation Links
Genes May Raise Risk of Neuroblastoma in Kids
Date:6/17/2009

Finding sheds light on cause of lethal cancer, expert says,,,,

WEDNESDAY, June 17 (HealthDay News) -- Researchers have identified a genetic trait that appears to boost the risk that a child will develop an often-fatal cancer that targets the nervous system.

The findings don't point toward a treatment, but they do give scientists more insight into neuroblastoma, said study co-author Dr. John Maris.

"We've learned a lot more about the underlying cause and the biology of the disease," said Maris, director of the Center for Childhood Cancer Research at the University of Pennsylvania School of Medicine, in Philadelphia.

Although not well known, neuroblastoma is the second most common form of cancer in children after leukemia, Maris said. The American Cancer Society estimates that about 650 children develop it each year in the United States.

Neuroblastoma strikes young children and infants, and is fatal in about two-thirds of the cases, Maris said.

Tumors develop in the nervous system and can appear along the spine and in the neck, chest and abdomen, he said. Many tumors begin in the adrenal gland, which produces adrenaline in the body.

Most children have an aggressive form of the disease and must be treated with intensive therapy, involving strategies such as chemotherapy, radiation and stem-cell transplants, Maris said.

The disease appears to run in families, but only in about 1 percent of cases, he said. In those cases, a child survives the cancer and grows up to have a child with the disease.

In the new study, researchers looked at genetic samples from hundreds of white children with the disease and compared them with those of children who didn't have it.

They found that a specific "copy number variation" -- a kind of genetic trait -- doubles the chances that a child will develop the cancer. A report on the findings appears in the June 18 issue of Nature
'/>"/>

Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. No Benefit in Testing for Genes Linked to Leg Clots
2. Lifestyle May Counter Blood Pressure Genes
3. MUHC researcher awarded $500,000 to study pathogenesis of infectious disease
4. Dads Genes May Play Greater Role Than Thought
5. A breakthrough in gastric carcinogenesis
6. Innovative New Wellness and Nutrition Program Leverages Latest Understanding of Relationship Between Diet and Genes
7. ThermoGenesis Appoints Chief Executive Officer J. Melville (Mel) Engle to Board of Directors
8. Organogenesis Launches Regenerative Medicine College Scholarship
9. Interleukin Genetics to Present Research Linking Perilipin Genes to Diet Response at the ADA Annual Meeting
10. Research Finds New Crop of Breast Cancer Genes
11. Researchers Spot Genes Linked to Testicular Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Genes May Raise Risk of Neuroblastoma in Kids
(Date:7/10/2014)... 10, 2014 One week ahead of ... Safety announced today it will extend compensation benefits to ... wages for workers displaced as a result of factory ... inspections have resulted in the closure of five factories ... cases, raising immediate safety concerns. In May, the Alliance—in ...
(Date:7/10/2014)... NY (PRWEB) July 10, 2014 CBPartners, ... sciences industry, has launched a new website. The ... well as increased access to the firm’s thought pieces, ... provides an ideal platform to showcase our insights, capabilities, ... issues,” says CBPartners’ Chief Executive Officer, Cyrus Chowdhury. ...
(Date:7/10/2014)... (PRWEB) July 10, 2014 A ... program that gets clients off to a great start ... can believe in, has launched a new Eating Disorders ... The new section highlights:, , Different ... Statistic Manual of Mental Disorders (DSM-IV), including anorexia nervosa, ...
(Date:7/10/2014)... A new study from Colorado School of Public ... health remains a major problem in the Navajo Nation ... among Native Americans is abysmal with more than three ... said Terrence Batliner, DDS, MBA, associate director of the ... of Public Health. "The number one problem is access ...
(Date:7/10/2014)... News) -- Most professional football players who have shoulder ... a new study finds. Shoulder instability is a ... return after surgery to fix the problem has been ... included 60 players who had shoulder stabilization surgery. Ninety ... to play, defined as playing in at least one ...
Breaking Medicine News(10 mins):Health News:Alliance for Bangladesh Worker Safety to Double Compensation for Displaced Factory Workers; Members Vote to Extend Wage Benefits from Two to up to Four Months 2Health News:CBPartners Announces New Website 2Health News:Latest A Forever Recovery Launches Eating Disorders Section on Website 2Health News:Study finds widespread oral health problems among Navajo 2Health News:Shoulder Surgery Gets NFL Players Back in the Game 2
... Lee, M.D., breast cancer researcher and assistant member ... grant from General Electric,s $100 million healthymagination Challenge ... genetic makeup to determine if they are predisposed ... GE,s healthymagination grant awarding initiative focuses on "finding ...
... Five Indiana University School of Medicine geriatricians are ... nationwide who will share in $2.5 million in career ... IU School of Medicine was one of the top-funded ... Medicine are: , Tochukwu Iloabuchi, M.D., advanced geriatrics ...
... H. Julia Hannay, the John and Rebecca Moores Professor ... 2012 Ester Farfel Award, a symbol of overall career ... faculty member. The annual award carries a cash prize ... honor recognizing the many roles that we may have ...
... Electrocardiograph (EKG) screening of young athletes can help identify those ... study. Researchers screened nearly more than 1,300 young athletes ... history, family history, a physical exam or prior EKG. Six ... cause sudden cardiac death. The study looked at how ...
... public health threats, early diagnosis of infectious diseases is ... globe where conventional medical tools like microscopes and cytometers ... to make disease screening quicker and simpler. ... or fluid samples are placed. Specific changes in the ...
... of small molecules that kill cancer cells caused by ... both cell and mouse models, demonstrate that the small ... proteins, thus killing the infected tumor cells. The ... issue of the journal Chemistry & Biology . ...
Cached Medicine News:Health News:Moffitt researcher awarded GE grant to develop tool to detect breast cancer metastasis genetic risks 2Health News:Awards to 5 IU School of Medicine physicians address critical need for geriatricians 2Health News:Neuropsychologist receives University of Houston's highest faculty honor 2Health News:Neuropsychologist receives University of Houston's highest faculty honor 3Health News:Heart Test Spots Sudden Death Risk in Young Athletes 2Health News:UCLA researchers combat global disease with a cell phone, Google Maps and a lot of ingenuity 2Health News:UCLA researchers combat global disease with a cell phone, Google Maps and a lot of ingenuity 3Health News:Small molecular bodyguards kill HPV-infected cancer cells by protecting tumor-suppressor 2Health News:Small molecular bodyguards kill HPV-infected cancer cells by protecting tumor-suppressor 3
(Date:7/10/2014)... 2014   Ventana Medical Systems, Inc.  (Ventana), a ... entered into an agreement with Merck KGaA, Darmstadt, ... in the United States and ... KGaA,s biopharmaceutical division on the development and commercialization of ... Ventana,s proprietary diagnostic assays. In alignment with Merck KGaA,s ...
(Date:7/10/2014)... 10, 2014   LabStyle Innovations Corp . ... announced the appointment of Professor Richard B. ... Board of Directors. Prof. Stone brings ... to LabStyle as an entrepreneur, venture capitalist public, ... governance expert. He currently serves on the board ...
(Date:7/10/2014)... -- Decision Resources Group finds that over half of ... Drug Administration,s (FDA) approval of Vifor Fresenius Medical Care ... by the FDA in November 2013 for the treatment ... dialysis. Other key findings from the report ... : , Bundling: Based ...
Breaking Medicine Technology:Ventana Medical Systems, Inc. and Merck KGaA, Darmstadt, Germany to develop companion diagnostic test for cancer treatment 2Ventana Medical Systems, Inc. and Merck KGaA, Darmstadt, Germany to develop companion diagnostic test for cancer treatment 3LabStyle Innovations Welcomes Richard B. Stone to its Board of Directors 2LabStyle Innovations Welcomes Richard B. Stone to its Board of Directors 3LabStyle Innovations Welcomes Richard B. Stone to its Board of Directors 4Half of Surveyed Nephrologists Report Moderate Familiarity with Velphoro, Which Received FDA Approval Late Last Year for the Treatment of Hyperphosphatemia in Dialysis 2Half of Surveyed Nephrologists Report Moderate Familiarity with Velphoro, Which Received FDA Approval Late Last Year for the Treatment of Hyperphosphatemia in Dialysis 3
... Study) Results Demonstrate ... of VH(R) IVUS in Drug Development, SAN DIEGO, ... [ESC Booth # A2-D403], a leading manufacturer of,intravascular ultrasound ... of its VH(R) IVUS (Virtual Histology IVUS) in,GlaxoSmithKline,s IBIS-2 ...
... 1 Calabar AB, a privately,held pharmaceutical company ... EUR 350,000 equity financing from the investment company,Karolinska ... a phase II study with repeated dosing. "We ... the minor glands will lead to improved outcomes ...
Cached Medicine Technology:Volcano's VH(R) IVUS Technology Used in Imaging Study of GlaxoSmithKline's Novel Investigational Compound, Darapladib 2Volcano's VH(R) IVUS Technology Used in Imaging Study of GlaxoSmithKline's Novel Investigational Compound, Darapladib 3Volcano's VH(R) IVUS Technology Used in Imaging Study of GlaxoSmithKline's Novel Investigational Compound, Darapladib 4
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: