Navigation Links
Genes May Affect Severity of Drug Addiction

TUESDAY, March 8 (HealthDay News) -- Treatment for drug addiction is affected by a person's genetic makeup and the duration of substance abuse, U.S. scientists report.

A research team at the Brookhaven National Laboratory found that drug addicts who have a certain genetic makeup have lower gray matter density -- and therefore fewer neurons -- in areas of the brain that are important for decision-making, self-control, learning and memory.

"This research shows that genes can influence the severity of addiction," study co-author Nelly Alia-Klein, a medical scientist, said in a Brookhaven news release. "The results suggest that addicted individuals with low MAOA [monoamine oxidase A] genotype may need a different kind of treatment than other addicted individuals who carry the high MAOA genotype."

She said that additional study is needed before treatment strategies should change. "However, addiction treatment professionals and others who manage addicted individuals, such as probation officers and judges, should be informed of these and other new findings in the neurobiology of drug addiction," Alia-Klein said.

The study, which included 40 men addicted to cocaine and 42 non-addicted men, also found that the longer someone abuses cocaine, alcohol and cigarettes, the lower the amount of gray matter in frontal areas of the brain (responsible for decision-making and self-control) and the hippocampus (responsible for learning and memory).

The finding, published March 7 in the Archives of General Psychiatry, suggests that ending drug use may help protect people against such brain changes.

"Only males were part of this study, and therefore it is important for future studies to examine these genetic and brain effects in females as well," Klein said. "Also, further studies will have to be done to track these gene-brain behavior patterns throughout a life span that influence the volume of the brain's neurons."

More information

The U.S. National Institute on Drug Abuse has more about drug addiction treatments.

-- Robert Preidt

SOURCE: Brookhaven National Laboratory, news release, March 7, 2011

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Genes Play Role in Prognosis With Non-Small Cell Lung Cancers
2. Researchers Who Discovered First Genes for Stuttering will Present Findings to the National Stuttering Association
3. Genes, environment, or chance?
4. UCLA study reveals how genes interact with their environment to cause disease
5. Long-Distance Runners May Have Endurance in Their Genes
6. Genes Behind Tooth Development Discovered
7. Smoking significantly increases risk of aneurysm in people with certain genes
8. Increasing neurogenesis might prevent drug addiction and relapse
9. Genetic Disease Foundation Encourages Americans to Know Their Genes at in Observance of World Rare Disease Day
10. Cluster of Genes Tied to Alcoholism
11. Cardiogenesis Reports Fourth Quarter and Full-Year 2009 Results
Post Your Comments:
Related Image:
Genes May Affect Severity of Drug Addiction 
(Date:11/28/2015)... ... November 28, 2015 , ... StatRad , ... added Chris Hafey and Claude Hooton to its board of directors. The announcement ... America (RSNA) 2015 Annual Meeting and continues to strategically transform its focus from ...
(Date:11/28/2015)... ... November 28, 2015 , ... Beginning November 30th at 6:00 a.m. EST until 11:59 p.m. EST, ... With possible savings of up to 20% off orders $80 or more to free gifts ... every few hours. , As a competitive e-commerce website for skin care and cosmetic needs, ...
(Date:11/27/2015)... ... November 27, 2015 , ... According to an article published November ... meeting in Washington D.C. revolved around the fact that proper dental care, both at-home ... stressed the link between periodontal disease (more commonly referred to as gum disease) and ...
(Date:11/27/2015)... (PRWEB) , ... November 27, 2015 , ... ... affecting the health care in America. As people age, more care is needed, ... costs are rising, and medical professionals are being overworked. The forgotten part of ...
(Date:11/27/2015)... ... November 27, 2015 , ... "When ... said an inventor from Hillside, N.J. "Many people catch diseases simply from sitting ... individuals will always be protected from germs." , He developed the patent-pending QUDRATECS ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... 26, 2015 3D bioprinting market ... to a new report by Grand View Research Inc. Rising ... which demands kidney transplantation is expected to boost the market ... for organ transplantation. --> 3D bioprinting market ... to a new report by Grand View Research Inc. Rising ...
(Date:11/26/2015)... November 26, 2015 ... universitetssjukhus ser potential att använda SyMRI för ... för patienter med multipel skleros (MS) ... med SyntheticMR AB för att kunna använda ... sjukhuset. Med SyMRI kan man generera flera ...
(Date:11/26/2015)... Research and Markets ( ) ... Future Horizons and Growth Strategies in the Italian ... Segment Forecasts, Competitive Intelligence, Emerging Opportunities" report ... --> This new 247-page report ... drug monitoring market, including emerging tests, technologies, instrumentation, ...
Breaking Medicine Technology: