Navigation Links
Genes Linked to Cholesterol in Cells Are Identified
Date:7/7/2009

Discovery could lead to new treatment targets, researchers say,,

TUESDAY, July 7 (HealthDay News) -- Twenty genes that play major roles in controlling cholesterol within cells have been identified by German researchers, who said that some of the genes may play a role in heart disease risk and offer new targets for drug treatment.

The 20 genes are likely to be "immediately relevant" for maintaining cholesterol levels in the cell, as well as controlling the uptake of low-density lipoprotein (LDL) cholesterol, the researchers explained in the July 8 issue of Cell Metabolism.

"High cholesterol in the blood is considered to be responsible for excess cardiovascular morbidity and mortality," Dr. Heiko Runz, of the University of Heidelberg, said in a news release from the journal's publisher. "Blood cholesterol levels are controlled by cholesterol in cells. Therefore, some of the genes identified by us as regulators of cellular cholesterol in future studies might turn out to be disease genes that contribute to hypercholesterolemia [high cholesterol] in some cases."

The genes identified in the study may also have potential as targets for new cholesterol-lowering drugs, the researchers say. And the new methods used in the study could help identify many more cholesterol genes.

"Until now, disease-associated genes affecting blood cholesterol levels have successfully been identified in single families and, more recently, genomic studies involving large number of patients," Runz and colleagues wrote.

"Most of what we know about the molecular machinery that keeps cholesterol levels balanced, however, comes from using cultured cell models," they said. "A functional analysis of many genes at once by the integrated functional genomics technology applied here now harbors potential not only to ease identification, but also to better describe the molecular roles of cholesterol regulators in health and disease
'/>"/>

Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Pathway links inflammation, angiogenesis and breast cancer
2. Traffic Fumes Plus Genes Boosts Kids Asthma Risk
3. New Database to Help Speed Search for Bipolar Disorder Genes
4. Is Perfect Pitch All in the Genes?
5. Discovery suggests location of genes for breast density, a strong risk factor for breast cancer
6. Genes Boost Risk for Rheumatoid Arthritis, Lupus
7. The genes involved in rheumatoid arthritis identified
8. If you think cancer genes are simple, you dont know JAK
9. Test for lung cancer looks for discomforting quiet among protective genes
10. Hushed Genes Might Mean Higher Lung Cancer Risk
11. EURYI project to understand how the brain wires during embryogenesis
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Genes Linked to Cholesterol in Cells Are Identified
(Date:8/4/2015)... ... August 05, 2015 , ... Renowned review site BestMillionaireDatingSites.com recently refreshed its list ... has been ranked as the best dating service in the segment. , A representative ... It is essential that people find the right dating platform so that they can ...
(Date:8/4/2015)... ... August 05, 2015 , ... The National Association ... inductee into its VIP Woman of the Year Circle. She is recognized with ... organization exclusively for professional women, boasting more than 700,000 members and over 200 ...
(Date:8/4/2015)... ... ... NOVA Pride , Northern Virginia’s largest and newest LGBTQ nonprofit organization, ... join them in paving “The Road Ahead” at the second annual Northern Virginia Pride ... 2015, from 12-9pm. In order to ensure the success of this important event, NOVA ...
(Date:8/4/2015)... ... 2015 , ... How cool is it to check in at your favorite ... "Now" feature will soon allow you to do just that. , Ahhaa is releasing ... the now feature. , Users will soon get to share what inspires them about ...
(Date:8/4/2015)... , ... August 04, 2015 , ... Statement by Paul ... the introduction of the Mental Health Reform Act of 2015 by Senators ... mental health reform a reality in America. , “This legislation and H.R. ...
Breaking Medicine News(10 mins):Health News:BestMillionaireDatingSites.com Publishes Reviews of the Best Dating Sites for Wealthy Singles 2Health News:NAPW Inducts Deborah Stevens, Executive Assistant to Chairman and CEO at Mirion Technologies, Inc., Into its VIP Woman of the Year Circle 2Health News:NOVA Pride Announces Theme for the 2015 Northern Virginia Pride Festival 2Health News:NOVA Pride Announces Theme for the 2015 Northern Virginia Pride Festival 3Health News:NOVA Pride Announces Theme for the 2015 Northern Virginia Pride Festival 4Health News:Ahhaa App Soon to Release the "Now" Feature 2Health News:MHA Applauds Introduction of Mental Health Reform Act of 2015 2Health News:MHA Applauds Introduction of Mental Health Reform Act of 2015 3
... a device to monitor diabetics' blood sugar levels and ... on finger-prick blood tests and injections. ,The ... computer to monitor the patient's blood sugar levels and ... a media report. ,The key is the ...
... playing in the park; ,Age is grey,a toothless hag ... four lines reflect the glory of youth and the dismal ... romanticize youth, they shrink from the thought of greying hair, ... infirmities of old age. ,With the changing ...
... of anabolic steroids is linked to criminal activity such ... study published on Monday. // ,The ... of the muscle-building drugs however also revealed that steroid ... violent crimes such as murder, assault, rape and property ...
... Canadians are getting heavier , but a new study by Statistics Canada ... the same pace as they did earlier. //Adults between 18-64 were ... The data showed that they have put on weight steadily , but ... decreased. ,This welcome news is thought to be due to the ...
... have no one to look out for them. They are ... in the community without any money or family of their ... condition that impairs their judgment or ability to communicate. ... baby boomers age. ,There is only one state-funded program ...
... many parts of the world, the moral and legal aspects ... Various methods of inducing //abortions have been used throughout history ... crossed five in North America, who died from toxic shock ... people questioning the safety of the combination of the drugs ...
Cached Medicine News:Health News:Botox – The 'Celebrity' Dru 2Health News:Steroid Use Linked to Crimes 2Health News:Hoosiers Live at the Mercy of Nursing Homes 2Health News:Hoosiers Live at the Mercy of Nursing Homes 3Health News:Medically Induced Abortions (MIAs) Causes More Deaths Due To Infection 2
(Date:8/4/2015)... P&S Market Research releases ... DRO analysis, market segmentation, market size and forecast, ... competitor profiles in: Global Industry Insight: ... Demand Forecast to 2020       (Logo: ... reports with detailed TOC on Global Drug of ...
(Date:8/4/2015)... Aug. 04, 2015 ... the addition of Jain PharmaBiotech,s new report ... to their offering. This report describes ... veterinary medicine and pharmaceuticals as well as improvement ... important in the application of biotechnology to manage ...
(Date:8/4/2015)... Among 1,000 U.S. consumers, the majority (65.3 ... consumers surveyed are aware of prescription savings cards, and ... according to findings from a new survey released today ... on improving the health and well-being of individuals, families ... men and women, ages 21 and older, on their ...
Breaking Medicine Technology:Global Drug of Abuse (DOA) Testing Market (Size of $2.9 Billion in 2014) to Witness 5% CAGR During 2015 - 2020 2Global Drug of Abuse (DOA) Testing Market (Size of $2.9 Billion in 2014) to Witness 5% CAGR During 2015 - 2020 3Global Drug of Abuse (DOA) Testing Market (Size of $2.9 Billion in 2014) to Witness 5% CAGR During 2015 - 2020 4Global Drug of Abuse (DOA) Testing Market (Size of $2.9 Billion in 2014) to Witness 5% CAGR During 2015 - 2020 5Animal Biotechnology 2014-2024 - 2015 Technologies, Markets and Companies Analysis 2Animal Biotechnology 2014-2024 - 2015 Technologies, Markets and Companies Analysis 3New Study Finds Consumers are Leaving Money at the Pharmacy 2New Study Finds Consumers are Leaving Money at the Pharmacy 3
... May 11 Despite significant international travel restrictions ... UBM International Media and sister company UBM Japan Co. Ltd. ... 2010 Japanese Pharma events cluster, which took place from 21-23 ... an increase of 3.8% over 2009 attendance levels, the success ...
... RF Technologies®, a leading provider of healthcare safety and security solutions, ... Safe Place® Infant Security Solutions. The soft, stretchy banding material and technologically ... a Safe Place bracelet is loose, tampered with or is cut. ... Smart Sense was developed ...
Cached Medicine Technology:UBM Japan Pharma Events Grow Despite Air Travel Disruptions 2UBM Japan Pharma Events Grow Despite Air Travel Disruptions 3UBM Japan Pharma Events Grow Despite Air Travel Disruptions 4Smart Sense(TM) From RF Technologies Upgrades Safe Place(R) Bracelets Using Industry-Leading Infant Security Technology, Fit and Comfort 2
Maxi XL Hybridization Oven for Extra Large bottles. 6 bottle (70 mm) rotisserie + shaker tray available for simultaneous use. Includes linear and orbital shaker trays, 4 extra large bottles, pack o...
... Dimensions (WxDxH): 31.1 x 13.6 x 15.3 ... 22.4 x 20.5 cm, Capacity: 4 - ... x 35 mm bottles, 4 - 150 ... 240 x 80 mm bottle, Power Requirements: ...
... : Temperature controlled oven containing a rotisserie ... incubation of Northern, Southern and Western blots. ... and staining. Use of bottle hybridizations allows ... enhanced sensitivity and reduced reagent costs. Acrylic/polycarbonate ...
... Minifold I system consists of four basic components: ... and metal clamping plate (see diagram). The sample ... producing spots, dots, or slots (see below). All ... as an accessory plate in conjunction with a ...
Medicine Products: