Navigation Links
Genes' Link to Certain Cancers Questioned
Date:5/27/2010

Because of their small size, studies tying genes to common tumors may be invalid, researchers say

THURSDAY, May 27 (HealthDay News) -- Small sample sizes may undercut the reliability of recent genome studies that seemingly uncovered genetic underpinnings for cancer risk, a Greek-American analysis cautions.

The observation is the result of a review of 45 studies that had harnessed technological innovations in so-called "whole genome sequencing" to attempt to identify specific genetic risk factors and link them to the risk for developing a range of cancers.

All the analyzed studies, published between 2007 and 2010, were listed in the National Human Genome Research Institute catalog.

The research team, led by Dr. John P.A. Ioannidis of the department of hygiene and epidemiology at the University of Ioannina School of Medicine in Athens, said their review of studies identified 92 genetic associations linked to the risk for developing various cancers.

More than half the highlighted genetic links concerned prostate, colorectal and/or breast cancer, they noted.

But the authors concluded that the explanatory power to predict individual cancer risk is "limited," they noted in a news release.

Ioannidis' team specifically noted that although the reviewed evidence for genetic roots to cancer risk was generally of statistical significance, the observed connections were relatively weak. They further noted that "almost all of them would also have small or very small effects."

Their findings are published in the May 26 online issue of The Journal of the National Cancer Institute.

More information

For more on genetics and cancer risk, visit the American Cancer Society.



SOURCE: Oxford Journals, May 26, 2010, news release


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Scientists ID a protein that splices and dices genes
2. Genes May Influence Preterm Births
3. New Research Shows Genes of Pregnant Women and Their Fetuses Can Increase the Risk of Preterm Labor
4. Genes of pregnant women and their fetuses can increase the risk of preterm labor
5. NIH scientists identify maternal and fetal genes that increase preterm birth risk
6. Very Obese People May Be Missing Genes
7. Scientists map out regulatory regions of genome, hot spots for diabetes genes
8. Mutating Genes May Lead to Premature Births
9. ThermoGenesis Corp. Names Healthcare Industry Executive Craig Moore to Board of Directors
10. Genes, Diet Offer New Clues to Parkinsons Disease
11. Discovery Links Genes to Pancreatic Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/24/2017)... ... February 24, 2017 , ... Indiana Fiber Network (IFN) ... company later this year. Dyer started as the Chairman of the Management Committee ... establishment of the corporation including the recruitment of investor/owners and development of the business ...
(Date:2/23/2017)... TX (PRWEB) , ... February 23, 2017 , ... ... announced an official 2017 partnership with The Jensie Gran Fondo of Marin. For ... and UVB rays with Thinksport’s broad-spectrum, mineral-based sunscreen. , “We are thrilled to ...
(Date:2/23/2017)... , ... February 23, 2017 , ... The American Cleft ... ACPA’s 74th Annual Meeting. KLS is a longtime supporter of the event. , ... exhibitor and Platinum Sponsor," said Dr. Bob Havlik, 2017 ACPA President. "KLS Martin has ...
(Date:2/23/2017)... ... February 23, 2017 , ... On April 13, ... symposium on “Doping in Sport: How the Culture Might Change,” in ... LLP. The symposium will be held at Pepperdine University in Malibu, California. , ...
(Date:2/23/2017)... ... February 23, 2017 , ... Healthcare Research & Analytics® (HRA®) ... fight against cancer, has produced a seminal study that asked cancer survivors and ... findings in a webinar, Defining Compassionate Care Through the Voices of Patients and ...
Breaking Medicine News(10 mins):
(Date:2/23/2017)... Research and Markets has announced the addition of the ... to their offering. ... The latest research Fibromyalgia Drugs Price Analysis and Strategies - ... market. The research answers the following questions: ... their clinical attributes? How are they positioned in the Global Fibromyalgia ...
(Date:2/23/2017)... Regulus Therapeutics Inc . (Nasdaq: RGLS), ... innovative medicines targeting microRNAs, today announced it will release ... Thursday, March 2, 2017 after the market closes. ... on March 2, 2017 at 5:00 p.m. Eastern Time ... results and provide a general business update.  A live ...
(Date:2/23/2017)... 23, 2017 According to a ... (X-ray Imaging Digital, Analog), MRI (Closed, Open), Ultrasound, CT, ... Oncology), End User (Hospitals, Imaging Centers) - Global Forecast ... global market over the forecast period of 2016 to ... Billion by 2021, at a CAGR of 6.6% from ...
Breaking Medicine Technology: