Navigation Links
Genes, Diet Offer New Clues to Parkinson's Disease
Date:1/25/2010

Interaction between genetics, environment may play role in onset, research suggests

MONDAY, Jan. 25 (HealthDay News) Researchers say they've spotted a new genetic risk factor for Parkinson's disease, as well as a link between the illness and two other factors, metabolism and vitamin B6.

"Our study reveals the interaction of genetic and environmental factors such as dietary habits in the pathogenesis of Parkinson's disease," Dr. Matthias Elstner of Germany's Ludwig-Maximilians-Universitat Munich, said in a news release from the German Research Center for Environmental Health.

Elstner is lead author of a new study published in the January issue of the journal Annals of Neurology.

The researchers studied neurons to understand how genes change their activity due to Parkinson's disease. They found a gene that seemed important and looked for it in 1,200 Parkinson's patients and 2,800 healthy people. It was discovered that a gene variant boosted the risk of the disease.

According to the study authors, the gene variant may affect the activity of an enzyme in the brain, called pyridoxal kinase (PDXK). The role of PDXK is to convert vitamin B6 from dietary sources into an active form that is required for the production of dopamine, a neurotransmitter that has long been known to be associated with Parkinson's disease.

"Although this variant is responsible for only a slight contribution to the overall risk for Parkinson's disease, our findings could aid in developing individualized therapies," Elstner said.

More information

The U.S. National Institute of Neurological Diseases and Stroke has more about Parkinson's disease.



-- Randy Dotinga



SOURCE: German Research Center for Environmental Health, news release, Jan. 18, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Nanomedical approach targets multiple cancer genes, shrinks tumors more effectively
2. Zebrafish provide useful screening tool for genes, drugs that protect against hearing loss
3. Genes, brain chemistry may dictate nicotine cravings, says CU-Boulder study
4. U.S. HealthWorks in San Diego Region Offering $15 H1N1 Vaccinations for both Walk-Ins and On-Site
5. SimpleWebBox Offers Free Websites for Non-Profit Organizations
6. Bizmatics and RevenueXL Announce Partnership to Offer Electronic Medical Records and Practice Management Software and Account Receivables Management Services
7. Author John Gwynne Prosser II Offers "The Solution for Brain Injuries and Bankruptcies" With Free Educational Video Hosted by Google
8. 100% Natural Remedy for Menopause Symptoms Offers Guaranteed Satisfaction
9. Anesthesia Healthcare Partners CEO to Speak at Upcoming Healthcare Conference to Offer Insight on Managing Costs in Healthcare Services
10. Equinox Holdings, Inc. Commences $400 Million Private Debt Offering
11. New Provider of Tablet/Capsule Packaging Solutions For Offers State-of-the-Art Equipment In The United States & Mexico
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... “The Journey: ... faced every danger possible to save lost souls in the Philippines. “The Journey: From ... Carole is a dedicated teacher of the Bible. She has taught all ages and ...
(Date:10/12/2017)... ... October 12, 2017 , ... CitiDent and San Francisco ... using cutting-edge Oventus O2Vent technology. As many as 18 million Americans are estimated ... in breathing. Oral appliances can offer significant relief to about 75 percent of ...
(Date:10/12/2017)... ... ... IsoComforter, Inc. ( https://isocomforter.com ), one of the Nation’s premier ... of the shoulder pad. The shoulder pad provides optimal support and full contact ... using cold therapy. By utilizing ice and water that is circulated from an insulated ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... that we intend to develop to enable prevention of a major side effect ... hearing loss, especially in pediatric patients. For cisplatin, hearing loss is FDA listed ...
(Date:10/12/2017)... ... October 12, 2017 , ... Leading pediatric oncology experts at Children’s ... the 49th Congress of the International Society of Paediatric Oncology (SIOP) Oct. ... Center for Cancer and Blood Disorders at Children’s National, and Stephen P. Hunger, ...
Breaking Medicine News(10 mins):
(Date:9/18/2017)... Sept. 18, 2017 EpiVax, Inc. ... bioinformatics and immune engineering, today announced a ... A (H7N9) vaccine. ... seasonal influenza and presents a challenge for ... exposure to be effective. Using state-of-the-art bioinformatics and ...
(Date:9/12/2017)... and NEW YORK , Sept. 12, 2017 ... performance ratings for global supply chains, has published the first annual edition ... CSR performance of more than 20,400 companies evaluated by EcoVadis, based on ... 2015 and 2016. ... EcoVadis Global CSR Risk & Performance Index ...
(Date:9/12/2017)... , Sept. 12, 2017  ValGenesis Inc., ... Solutions (VLMS), is pleased to announce the appointment ... member of its Board of Directors and Chairman ... VLMS enables life science companies to manage their ... use of paper in this process. Furthermore, ValGenesis ...
Breaking Medicine Technology: