Navigation Links
Genes, Diet Offer New Clues to Parkinson's Disease
Date:1/25/2010

Interaction between genetics, environment may play role in onset, research suggests

MONDAY, Jan. 25 (HealthDay News) Researchers say they've spotted a new genetic risk factor for Parkinson's disease, as well as a link between the illness and two other factors, metabolism and vitamin B6.

"Our study reveals the interaction of genetic and environmental factors such as dietary habits in the pathogenesis of Parkinson's disease," Dr. Matthias Elstner of Germany's Ludwig-Maximilians-Universitat Munich, said in a news release from the German Research Center for Environmental Health.

Elstner is lead author of a new study published in the January issue of the journal Annals of Neurology.

The researchers studied neurons to understand how genes change their activity due to Parkinson's disease. They found a gene that seemed important and looked for it in 1,200 Parkinson's patients and 2,800 healthy people. It was discovered that a gene variant boosted the risk of the disease.

According to the study authors, the gene variant may affect the activity of an enzyme in the brain, called pyridoxal kinase (PDXK). The role of PDXK is to convert vitamin B6 from dietary sources into an active form that is required for the production of dopamine, a neurotransmitter that has long been known to be associated with Parkinson's disease.

"Although this variant is responsible for only a slight contribution to the overall risk for Parkinson's disease, our findings could aid in developing individualized therapies," Elstner said.

More information

The U.S. National Institute of Neurological Diseases and Stroke has more about Parkinson's disease.



-- Randy Dotinga



SOURCE: German Research Center for Environmental Health, news release, Jan. 18, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Nanomedical approach targets multiple cancer genes, shrinks tumors more effectively
2. Zebrafish provide useful screening tool for genes, drugs that protect against hearing loss
3. Genes, brain chemistry may dictate nicotine cravings, says CU-Boulder study
4. U.S. HealthWorks in San Diego Region Offering $15 H1N1 Vaccinations for both Walk-Ins and On-Site
5. SimpleWebBox Offers Free Websites for Non-Profit Organizations
6. Bizmatics and RevenueXL Announce Partnership to Offer Electronic Medical Records and Practice Management Software and Account Receivables Management Services
7. Author John Gwynne Prosser II Offers "The Solution for Brain Injuries and Bankruptcies" With Free Educational Video Hosted by Google
8. 100% Natural Remedy for Menopause Symptoms Offers Guaranteed Satisfaction
9. Anesthesia Healthcare Partners CEO to Speak at Upcoming Healthcare Conference to Offer Insight on Managing Costs in Healthcare Services
10. Equinox Holdings, Inc. Commences $400 Million Private Debt Offering
11. New Provider of Tablet/Capsule Packaging Solutions For Offers State-of-the-Art Equipment In The United States & Mexico
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/28/2017)... ... June 28, 2017 , ... Eating disorders have the highest mortality rate of ... one person dies as a direct result from an eating disorder in the U.S. ... providers. The iaedp Foundation meets this challenge by offering what has become the leading ...
(Date:6/28/2017)... ... June 28, 2017 , ... Park Systems , ... Luncheon for all SEMICONWest attendees and Park customers on July 11, 2017 ... from Dr. Sang-il Park, Chairman & CEO of Park Systems, and Prof. Krishna ...
(Date:6/28/2017)... (PRWEB) , ... June 28, 2017 , ... ... assistance and financial consultations to communities in northern Virginia and DC, is announcing ... help provide for patients with Alzheimer’s and other disorders that lead to memory ...
(Date:6/27/2017)... PA and London UK (PRWEB) , ... June 27, 2017 , ... ... applying to a clinical study is whether they can trust the sponsor to pay ... it is vital that sponsors and CROs establish payment strategies that encourage sites to ...
(Date:6/27/2017)... ... 27, 2017 , ... Building on the success of the ... sixth state to pass legislation which ensures that children can possess and use ... the states of Alabama, Arizona, Florida, Utah and Washington who have also approved ...
Breaking Medicine News(10 mins):
(Date:6/13/2017)... Ind. , June 13, 2017 Zimmer Biomet ... musculoskeletal healthcare, today announced that the U.S. Food and Drug ... dated June 3, 2015 relating to its Zhejiang, ... "The successful clearance of the ... manufacturing facility is a measure of the progress ...
(Date:6/10/2017)... June 9, 2017  Shane K. Burchfield, DPM, is recognized by ... as a Podiatrist in Alabama . ... First Foot Care. He brings over 20 years of experience, as ... and healthcare, to his role. ... PC is pleased to welcome you to his practice," ...
(Date:6/8/2017)... 8, 2017  Less than a month ago, amateur ... 200,000 companies, including hospital networks, in over 150 countries. ... of the largest online extortion attempts ever recorded. With ... it is imperative that providers understand where the risks ... this — and many other very real cyber threats.  ...
Breaking Medicine Technology: