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General Anesthesia Boosts Post-Op Pain
Date:6/23/2008

throughout the body just before and after surgery contributes to the pain felt by patients when they wake up after surgery.

"This is a provocative finding in terms of the clinical setting, because it was not really recognized that use of these drugs results in release of lots of chemicals that recruit immune cells to the nerves, which causes more pain or inflammation," Ahern said.

While some general anesthetics don't activate the TRPA1 receptor, they may not be as effective in other ways.

"This tells us that there is room for improvement in these drugs," Ahern said.

The study was published in the June 23 issue of the journal Proceedings of the National Academy of Sciences.

More information

The National Institute of General Medical Sciences has more about anesthesia.



-- Robert Preidt



SOURCE: Georgetown University Medical Center, news release, June 23, 2008


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