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GeneThera - CHANGING DIRECTIONS - an Update to Shareholders
Date:11/3/2008

and have a four-chambered stomach. Some of the more common ruminants are: cattle, sheep, goats, deer, antelope, and bison. Johne's disease has been reported in all of these animals but is most commonly seen in dairy cattle. The result most commonly reported from infected cattle is a serious decline in herd milk production. The animal develops uncontrolled diarrhea and slowly wastes away to a point of death.

The U.S. rate of dairy herd infection is similar to that reported in other countries using similar tests: Netherlands (55%), Belgium (22%), Austria (7%), England and Wales (17%), Denmark (47%), New Zealand (60%) and the state of Victoria in Australia (22%). The herd infection rate in U.S. beef cattle is lower although not many surveys have been reported. A 1997 survey found that: 7.8% of beef herds were infected using the same survey methods as for dairy cattle. Infection rates in beef cattle a most likely lower than in dairy cattle due to differences in animal husbandry practices.

About E.Coli 057.h7

There are a variety of Escherichia coli bacteria present in nature. They are usually found in the intestines of healthy humans and healthy animals. Even though these bacteria offer beneficial properties, there are those variations, or strains that are pathogenic (have the ability to cause disease). Escherichia coli 0157:H7 is one particular strain that is "... an emerging cause of food borne illness ..." Symptoms such as bloody diarrhea and abdominal cramps may be observed or no such symptoms may appear. The elderly and children under five years old are highly susceptible to Hemolytic Uremic Syndrome, a disease in which red blood cells are destroyed and kidneys fail. According to the CDC " ... there may be about 70,000 infections with E. coli O157 each year in the United States. We can only estimate because we know that many infected people do not seek medical care, many do not submit a stool specimen for testing, and many labs do not test for
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