Navigation Links
Gene which protects against lung cancer identified
Date:12/2/2008

A study led by researchers at The University of Nottingham has identified a gene that protects the body from lung cancer.

The research, published in the journal Proceedings of the National Academy of Sciences, USA and funded by a 72,000 grant from the British Lung Foundation, has found that the tumour suppressor gene, LIMD1, is responsible for protecting the body from developing lung cancer paving the way for possible new treatments and early screening techniques.

Lead researcher Dr Tyson Sharp and his University of Nottingham team, together with US collaborator Dr Greg Longmore, set out to examine if loss of the LIMD1 gene correlated with lung cancer development.

The University of Nottingham team examined lung cancer tissue from patients with the disease and compared it to healthy lung tissue. They found that the LIMD1 gene was missing in the majority of lung cancer samples, indicating that the presence of the LIMD1 gene protects the body against lung cancer.

Dr Greg Longmore's team in the USA supported these findings, using a mouse without the LMID1 gene which developed lung cancer.

Dr Sharp said: "The LIMD1 gene studied in this research is located on part of chromosome 3, called 3p21.

"Chromosome 3p21 is often deleted very early on in the development of lung cancer due to the toxic chemicals in cigarettes, which implies that inactivation of LIMD1 could be a particularly important event in early stages of lung cancer development.

"We are now going to extend these finding by developing LIMD1 as a novel prognostic tool for detection of early stage lung cancer."

Lung cancer is the UK's biggest cancer killer, claiming around 33,600 lives a year. Ninety per cent of cases are caused by smoking. At present lung cancer is often detected late, meaning that 80 per cent of patients die within a year of being diagnosed.

Dame Helena Shovelton, Chief Executive of the British Lun
'/>"/>

Contact: Dr. Tyson Sharp
tyson.sharp@nottingham.ac.uk
44-011-582-30108
University of Nottingham
Source:Eurekalert

Page: 1 2

Related medicine news :

1. The science behind the food we eat and the earth on which it grows
2. Which intervention would do the most to improve the health of the extreme poor?
3. Marlo Thomas and St. Jude Childrens Research Hospital(R) Announce Hitting The 50-Partner Milestone as They Kick Off the Fourth Annual Thanks and Giving(R) Campaign Which Asks America to Support St. Jude While Shopping This Holiday Season
4. The Polls are Open! America Votes to Decide Which Hospital is the Most Deserving of Siemens Newest MRI Technology
5. Which segments of the gastrointestinal tract does Salmonella enteritidis penetrate?
6. OxySure(R) Systems, Inc. Named to 2008 Worlds Best Technologies (WBT) List For its Unique, Safe and Easy to Use Portable Emergency Oxygen Generator, Which Provides Medical Oxygen Without the Need for Compressed Tanks
7. Study identifies which men are likely to have persistent prostate cancer
8. Bradmer announces Phase II results published in newly diagnosed glioblastoma which demonstrate improved survival and support upcoming Phase III study
9. Researchers describe mechanisms by which capon gene causes heart rhythm disturbances
10. Which came first, social dominance or big brains? Wasps may tell
11. Hats Off to the Red Hat Society, Which Turns 10 Today
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/1/2014)... Today marks the final day prosthodontist Dr. ... Oxnard and Woodland Hills, Calif., is in the southern ... , “Speaking to this group of specialists allows more ... the help and care they deserve,” Dr. Jivraj said. ... work, providing cosmetic dentistry, correcting bite issues, placing implants, ...
(Date:10/1/2014)... (PRWEB) October 01, 2014 Generic drug ... retail generics increasing in price in the last 12 ... Inc.’s (AIS) Drug Benefit News (DBN) interviewed a plan ... means for pharmacies and health plans. , “When ... rising generic acquisition costs, these cost increases squeeze pharmacies’ ...
(Date:10/1/2014)... October 01, 2014 UP4 Probiotics will ... WOMEN’S probiotic to The National Network to End Domestic ... This organization was chosen through nationwide polling that took ... social media outlets. , “We are proud to ... portion of every sale of UP4 Women’s Probiotics during ...
(Date:10/1/2014)... 2014 Long-acting insulin is safer and more ... 1 diabetes, according to new research published in ... at once-daily and twice-daily doses of both long- ... cost-effectiveness. , "In patients with Type 1 ... to intermediate-acting insulin when it came to controlling ...
(Date:10/1/2014)... 2014 This weekend Pope Francis drew world-wide ... Speaking to 40,000 seniors in St. Peter's Square in ... elderly. "Violence against the elderly is as inhuman as ... are old people just discarded, victims of an abandonment that ... a throw-away culture that is hurting our world so much," ...
Breaking Medicine News(10 mins):Health News:Internationally Respected Oxnard Dentist Concludes All-on-4™ Dental Implants Training Today 2Health News:Internationally Respected Oxnard Dentist Concludes All-on-4™ Dental Implants Training Today 3Health News:Internationally Respected Oxnard Dentist Concludes All-on-4™ Dental Implants Training Today 4Health News:Internationally Respected Oxnard Dentist Concludes All-on-4™ Dental Implants Training Today 5Health News:Rising Generic Drug Prices Affect Pharmacies, Insurers Alike, Reports AIS Newsletter 2Health News:Rising Generic Drug Prices Affect Pharmacies, Insurers Alike, Reports AIS Newsletter 3Health News:UP4 Probiotics Partners with The National Network to End Domestic Violence 2Health News:Long-acting insulin is safer, more effective for patients with Type 1 diabetes 2Health News:Pope Francis Shines New Spotlight on Neglect of Elderly, Survey Finds Elder Self-Neglect is a Growing and Hidden Problem in U.S. says NAPGCM 2Health News:Pope Francis Shines New Spotlight on Neglect of Elderly, Survey Finds Elder Self-Neglect is a Growing and Hidden Problem in U.S. says NAPGCM 3
... software medication solution reduces complexity in, patient-specific medication ... ... LAS VEGAS, ASHP, Dec. 3 Ushering in ... OMCL ) a leading provider,of system solutions ...
... with Centers of Influence, POWAY, Calif., Dec. ... leading provider of medical diagnostic imaging systems,and services ... the signing of a letter of agreement with ... of the agreement, the fifth since the inception ...
... advertisements are appearing on television, the bulk of ... spend annually to market their products is targeted ... students. , A literature review by researchers ... the Regenstrief Institute, Inc. published in the December ...
... , , MONDAY, Dec. 3 (HealthDay News) -- Avandia, a ... bone loss, according to a new study conducted in mice. ... may speed osteoporosis, the thinning of the bones that can ... appear in the Dec. 2 online issue of Nature ...
... ANGELES, Dec. 2 Hurricane Katrina was one ... and was the costliest (at an,estimated $86 billion.) ... in the aftermath. Witnessing the,destruction/displacement from the West ... to take his new school training techniques, with,old ...
... Everything from Christmas trees to fake snow can trigger symptoms, ... It,s easy for the holidays to become the season ... or other allergies and asthma, say experts at the American ... preventive measures can cut symptoms to a minimum, they say. ...
Cached Medicine News:Health News:Omnicell Debuts Industry's First Total Automated Patient-Specific Management Solution 2Health News:Omnicell Debuts Industry's First Total Automated Patient-Specific Management Solution 3Health News:Digirad Corporation and The Methodist Hospital in Houston Sign Letter of Agreement 2Health News:Digirad Corporation and The Methodist Hospital in Houston Sign Letter of Agreement 3Health News:Digirad Corporation and The Methodist Hospital in Houston Sign Letter of Agreement 4Health News:Do medical schools affect the way future doctors interact with drug companies? 2Health News:Diabetes Drug Avandia Could Weaken Bones 2Health News:CJ Transforms His Functional Fitness Program Into an Additional Resource for the Hurricane Katrina Survivors 2Health News:CJ Transforms His Functional Fitness Program Into an Additional Resource for the Hurricane Katrina Survivors 3Health News:'Tis the Season For Allergy, Asthma 2
(Date:10/1/2014)... 1, 2014 Sophia Genetics, ... domaine de l,analyse des données issues du SNG ... de diagnostic in vitro (IVD) du gène CFTR ... la mucoviscidose dans un seul essai SGN. La ... les types de variantes par l,intermédiaire d,un seul ...
(Date:9/30/2014)... 2014  Wrightington, Wigan and ... MDRX ) are delighted to announce WWL,s decision ... health information system. The system will be implemented across ... way WWL delivers healthcare in the future. ... of on-time and on-budget system implementations as well as ...
(Date:9/30/2014)... 2014 This study provides an analysis ... solutions including nuclear imaging informatics, PET imaging informatics, ... assesses the size of the market based on ... projects future growth based on the current drivers ... place in the broader markets for imaging equipment, ...
Breaking Medicine Technology:Sophia Genetics lance une analyse complète du gène CFTR dans un essai clinique SGN 2Sophia Genetics lance une analyse complète du gène CFTR dans un essai clinique SGN 3Wrightington, Wigan and Leigh NHS Foundation Trust selects Allscripts Sunrise 2Wrightington, Wigan and Leigh NHS Foundation Trust selects Allscripts Sunrise 3Wrightington, Wigan and Leigh NHS Foundation Trust selects Allscripts Sunrise 4Analysis of the US Molecular Imaging Informatics Market 2Analysis of the US Molecular Imaging Informatics Market 3
... 10, 2010 The American Council on Exercise (ACE), ... fitness certification, education and training organization in the world, ... will focus on eliminating obesity in America.  As an ... the critical need to regularly engage in physical activity ...
... 2010 Luminex Corporation (Nasdaq: LMNX ... the Stephens Fall Investment Conference to be held ... (Logo:   http://photos.prnewswire.com/prnh/20100104/LUMINEXLOGO ) (Logo:   ... Patrick J. Balthrop, president and chief executive officer, ...
Cached Medicine Technology:American Council on Exercise (ACE) Announces Nationwide Effort to Eliminate Obesity in America 2American Council on Exercise (ACE) Announces Nationwide Effort to Eliminate Obesity in America 3Luminex Corporation to Present at Stephens Fall Investment Conference 2
... Millipore has developed a range of ... match specific water quality requirements. Each ... is designed to specifically target contaminants ... HPLC, molecular biology and ICP-MS. The ...
Adjustable speed vortex with inter-changeable heads , 110 V...
Inquire...
Adjustable speed vortex with inter-changeable heads, 110 V...
Medicine Products: