Navigation Links
Gene variation makes alcoholism less likely in some survivors of sexual abuse
Date:2/2/2010

as suggested that when the environmental risk factors occur during key periods of brain development, genes and environment working together can increase the likelihood an individual will become alcohol dependent. Child sexual abuse is one of the environmental stressors that can interact with genes to significantly increase the risk for alcohol problems.

But the researchers report in the January issue of Addiction Biology that people with a particular pattern of genetic markers seem to be protected against alcohol problems, even if they were sexually abused as children.

Those who were protected carry a set of genetic variations that scientists call the H2 haplotype. Similar to a blood type, a haplotype is more than just a single genetic mutation. It is a normally occurring pattern of gene variants that are statistically associated with one another so that when scientists find a few genetic markers, they can successfully predict what other genetic variations will occur within a particular region of DNA.

"We looked at how genes and environment interact," says Elliot C. Nelson, M.D., lead author of the study. "Our analysis included both sexual abuse and information about the DNA region that carries the H2 haplotype. People who carry that genetic pattern were protected against the risks for alcohol consumption and alcohol dependence typically associated with sexual abuse."

Other sexual abuse victims in the study had the alternate genetic pattern known as the H1 haplotype. Those individuals had three times the risk of heavy drinking and alcohol dependence as those who had not been sexually abused.

"They drank much more alcohol and had a significantly greater risk for problems," says Nelson, an associate professor of psychiatry. "But abuse victims with the H2 haplotype seemed to be completely protected against those risks."

Nelson's team studied data from more than 1,100 people in 476 Australian families who p
'/>"/>

Contact: Diane Duke Williams
williamsdia@wustl.edu
314-286-0111
Washington University in St. Louis
Source:Eurekalert

Page: 1 2 3 4 5

Related medicine news :

1. Climatic variations influence the emergence of cholera in Africa
2. Study looks at mitochondrial variation in sperm traits and sperm competitive ability
3. Genetic variation affects smoking cessation treatment
4. Optherion Licenses Worldwide Rights to Develop Age-Related Macular Degeneration Diagnostics Based on Chromosome 10 Genetic Variations
5. Study questions impact of hemoglobin variations on mortality in dialysis patients
6. Human genetic variation -- Sciences Breakthrough of the Year
7. More Gene Variations Found That Raise Prostate Cancer Risk
8. Study Finds Variations in Doses of Radiation Therapy
9. New report highlights variations in approaches to thoracic surgery in the United Kingdom and Ireland
10. Genetic variations raise lung cancer risk for smokers and ex-smokers
11. Study shows gene variations may predict risk of breast cancer in women
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/20/2014)... Developers of FCPX 3rd ... plugin for Final Cut Pro X entitled TranSlice Volume ... allows users to create hand drawn text animations without ... CEO of Pixel Film Studios. “TranSlice Volume 5 was ... an easy to use interface.” , TranSlice Volume 5 ...
(Date:12/20/2014)... Twin Cities DI Day is recognized as the premier ... financial professionals come together each year to hear up ... to protect their clients and to be inspired by ... of disability. , On September 23rd, 2014, financial professionals ... The 13th Annual Twin Cities DI Day where they ...
(Date:12/20/2014)... Today, Balfleet.com, one of the most ... offering 50%-70% off on its Mother of the ... mother of the bride dresses from Balfleet.com feature gorgeous ... accessible and takes pride in providing high quality dresses ... offering great discounts on our mother of the bride ...
(Date:12/19/2014)... Montrose, Colorado (PRWEB) December 20, 2014 It’s ... many, travel is something that is put to the wayside ... those who still have that travel “itch” and that burning ... Inn Montrose accommodates families on their journey to Telluride with ... trip, get visitors to and from the resort, and ensure ...
(Date:12/19/2014)... Sub Zero Ice Cream is partnering up ... Sunday the 28th from 2pm-6pm at the Expo Center on ... Sarasota, FL. , Inquiries regarding time slots and signing up, ... the donating process, Sub Zero Ice Cream & Yogurt will ... cream. , About Sub Zero Ice Cream & Yogurt ...
Breaking Medicine News(10 mins):Health News:Pixel Film Studios released a new transition entitled TranSlice Volume 5 exclusively for Final Cut Pro X 2Health News:The 13th Annual Twin Cities DI Day Now On Video 2Health News:The 13th Annual Twin Cities DI Day Now On Video 3Health News:Balfleet.com is Offering 50%-70% Off of its Mother of the Bride Dresses 2Health News:Days Inn Montrose Colorado Delivers Last Minute Holiday Season Ski Getaway Accommodations 2Health News:Shark Tank’s Sub Zero Ice Cream Sponsors Blood Drive 2
... Safety and Efficacy Study of Zolpidem Tartrate ... an As-Needed BasisEvaluation of Ondansetron Augmentation in ... May 21 Transcept Pharmaceuticals, Inc. (Nasdaq: ... company focused on the development and commercialization ...
... offers patients better results and quicker recovery as ... currently on the market; Now available in powerful ... Palomar Medical Technologies, Inc. (Nasdaq: PMTI ... systems for cosmetic treatments, announced today the success ...
... Inc. (MDLH. PK) ( http://www.mitcanada.ca http://www.mitinvest.ca ), ... the Joint Venture Agreement with its Chinese partners. , ... most recent trip to China having completed the negotiations and ... has also received an initial order of 120 Agro-Jet(R) for ...
... Challenging Anatomy Consistent with Superior Results from Randomized ... presented today at EuroPCR from an international, post-approval, ... Everolimus Eluting Coronary Stent System demonstrated low rates ... and major adverse cardiac events (MACE) in a ...
... finds many women use spending sprees to boost emotional well-being ... -- When dealing with financial worries, some women may actually ... shows. , The poll of 700 women found that 79 ... themselves an emotional boost. About 40 percent listed "depression" and ...
... compared to vaginal birth newborns, researchers say , , THURSDAY, ... elective, repeat cesarean section delivery are nearly twice as ... unit (NICU) than those born vaginally after the mother ... , These c-section babies are also more likely to ...
Cached Medicine News:Health News:Transcept Pharmaceuticals Presents Data from Studies of Two Product Candidates at Annual Meeting of the American Psychiatric Association 2Health News:Transcept Pharmaceuticals Presents Data from Studies of Two Product Candidates at Annual Meeting of the American Psychiatric Association 3Health News:Transcept Pharmaceuticals Presents Data from Studies of Two Product Candidates at Annual Meeting of the American Psychiatric Association 4Health News:New Clinical Data Shows Significant Improvement in the Appearance of Fat Using SlimLipo(TM) Laser 2Health News:New Clinical Data Shows Significant Improvement in the Appearance of Fat Using SlimLipo(TM) Laser 3Health News:New Clinical Data Shows Significant Improvement in the Appearance of Fat Using SlimLipo(TM) Laser 4Health News:MIT is pleased to announce that it has signed the Joint Venture agreement with its Chinese partners and has received an initial order of 120 units for Animal vaccination 2Health News:Abbott's XIENCE V(R) Demonstrates Impressive Low Rates of Repeat Procedure, Stent Thrombosis and Major Adverse Cardiac Events in Complex, 'Real World' Patients in SPIRIT V Study 2Health News:Abbott's XIENCE V(R) Demonstrates Impressive Low Rates of Repeat Procedure, Stent Thrombosis and Major Adverse Cardiac Events in Complex, 'Real World' Patients in SPIRIT V Study 3Health News:Abbott's XIENCE V(R) Demonstrates Impressive Low Rates of Repeat Procedure, Stent Thrombosis and Major Adverse Cardiac Events in Complex, 'Real World' Patients in SPIRIT V Study 4Health News:Abbott's XIENCE V(R) Demonstrates Impressive Low Rates of Repeat Procedure, Stent Thrombosis and Major Adverse Cardiac Events in Complex, 'Real World' Patients in SPIRIT V Study 5Health News:Abbott's XIENCE V(R) Demonstrates Impressive Low Rates of Repeat Procedure, Stent Thrombosis and Major Adverse Cardiac Events in Complex, 'Real World' Patients in SPIRIT V Study 6Health News:Shop 'Til You Drop: You May Feel Better 2Health News:Risk to Baby Rises With Repeat C-Sections 2Health News:Risk to Baby Rises With Repeat C-Sections 3
(Date:12/19/2014)... Ill. , Dec. 19, 2014   Hospira, ... leading provider of injectable drugs and infusion technologies, today ... Morgan 33rd Annual Healthcare Conference on Wednesday, Jan. 14, ... presentation is scheduled to begin at 10:30 a.m. Pacific ... available to all interested parties through a live audiocast ...
(Date:12/19/2014)... -- Monarch America Inc. (OTCQB: CANK) ("Monarch America" or the ... this review of the Company,s recent achievements and strategic ... this past year, we achieved many of our early ... say that Monarch America is in a stronger and ... stated Eric Hagen , CEO of Monarch America ...
(Date:12/19/2014)... , Dec. 18, 2014 Somewhere between dropping ... health was forgotten. But Audicus , a next-generation ... better this new year. Hearing loss is ... aging population, though it is often unaddressed. Forty-eight million ... has a hearing aid, mainly due to price. Hearing ...
Breaking Medicine Technology:Monarch America Inc. CEO Reviews Recent Achievements and Provides Outlook for 2015 2Monarch America Inc. CEO Reviews Recent Achievements and Provides Outlook for 2015 3Audicus Will Help People Resolve to Hear Better in 2015 2
... IDAHO FALLS, Idaho, Dec. 12, 2011 International Isotopes ... a conference call to give an update of the ... performance of its core business segments as well as ... depleted uranium de-conversion project.What:  , International Isotopes Inc. General ...
... of Eli Lilly and Company (NYSE: LLY ) ... December 12, 2011. Baicker, 40, is Professor of Health Economics ... Harvard School of Public Health. She is also a research ... elected member of the Institute of Medicine. As a member of ...
Cached Medicine Technology:International Isotopes Inc. Announces Conference Call to Give an Update on the Company's General Business Status 2Katherine Baicker Elected to Lilly Board of Directors 2
... path that allows users to take full ... potential to combine two units offers fully ... stimulating coil. The ability to change pulse ... level of each Magstim 200 allows for ...
... is a surgical approach to glaucoma management ... application. The ciliary body (which produces aqueous ... the anterior or posterior segment, through the ... are easily and accurately identified utilizing endoscopy. ...
... surgical approach to glaucoma management that employs ... ciliary body (which produces aqueous humour) is ... or posterior segment, through the endoscope in ... and accurately identified utilizing endoscopy. This allows ...
... of German Craftsmanship have produced ... the world. Ocutek® now makes ... holders of the coveted Meisterbrief ... apprenticeship, are qualified to become ...
Medicine Products: