Navigation Links
Gene variation makes alcoholism less likely in some survivors of sexual abuse
Date:2/2/2010

as suggested that when the environmental risk factors occur during key periods of brain development, genes and environment working together can increase the likelihood an individual will become alcohol dependent. Child sexual abuse is one of the environmental stressors that can interact with genes to significantly increase the risk for alcohol problems.

But the researchers report in the January issue of Addiction Biology that people with a particular pattern of genetic markers seem to be protected against alcohol problems, even if they were sexually abused as children.

Those who were protected carry a set of genetic variations that scientists call the H2 haplotype. Similar to a blood type, a haplotype is more than just a single genetic mutation. It is a normally occurring pattern of gene variants that are statistically associated with one another so that when scientists find a few genetic markers, they can successfully predict what other genetic variations will occur within a particular region of DNA.

"We looked at how genes and environment interact," says Elliot C. Nelson, M.D., lead author of the study. "Our analysis included both sexual abuse and information about the DNA region that carries the H2 haplotype. People who carry that genetic pattern were protected against the risks for alcohol consumption and alcohol dependence typically associated with sexual abuse."

Other sexual abuse victims in the study had the alternate genetic pattern known as the H1 haplotype. Those individuals had three times the risk of heavy drinking and alcohol dependence as those who had not been sexually abused.

"They drank much more alcohol and had a significantly greater risk for problems," says Nelson, an associate professor of psychiatry. "But abuse victims with the H2 haplotype seemed to be completely protected against those risks."

Nelson's team studied data from more than 1,100 people in 476 Australian families who p
'/>"/>

Contact: Diane Duke Williams
williamsdia@wustl.edu
314-286-0111
Washington University in St. Louis
Source:Eurekalert

Page: 1 2 3 4 5

Related medicine news :

1. Climatic variations influence the emergence of cholera in Africa
2. Study looks at mitochondrial variation in sperm traits and sperm competitive ability
3. Genetic variation affects smoking cessation treatment
4. Optherion Licenses Worldwide Rights to Develop Age-Related Macular Degeneration Diagnostics Based on Chromosome 10 Genetic Variations
5. Study questions impact of hemoglobin variations on mortality in dialysis patients
6. Human genetic variation -- Sciences Breakthrough of the Year
7. More Gene Variations Found That Raise Prostate Cancer Risk
8. Study Finds Variations in Doses of Radiation Therapy
9. New report highlights variations in approaches to thoracic surgery in the United Kingdom and Ireland
10. Genetic variations raise lung cancer risk for smokers and ex-smokers
11. Study shows gene variations may predict risk of breast cancer in women
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/30/2014)... Vail and Beaver Creek, Colo., skiers ... with “Blind Skier.” Those skiers and guides are enjoying ... Guides , a non-profit organization founded in 2001 that ... (VIPs) for snow sport opportunities. Visually impaired skiers and ... and pick up an application to participate in the ...
(Date:7/30/2014)... Push to Walk and Macy’s invite ... For A Cause” charity shopping event on August 23, ... one-day-only shopping event created to support local charities’ fundraising ... for charities across the country since 2006. Customers can ... from Push to Walk now. , “Macy’s ...
(Date:7/30/2014)... Calling all runners in the Richmond, VA region. ... host a monthly Runner’s Injury Clinic at the ... the second Monday of each month through the end of ... 10 and December 8. , The clinics run from ... running shoes and attire, will receive a complimentary evaluation of ...
(Date:7/30/2014)... (PRWEB) July 30, 2014 The ... with the Penn's Abramson Cancer Center, will host a ... together area experts in the field of mesothelioma. September ... The conference is open to the public, and specifically ... and those who have been exposed to asbestos. , ...
(Date:7/30/2014)... Ohio (PRWEB) July 31, 2014 CareSource, ... Douglas A. Fecher President and CEO, Wright-Patt Credit Union, ... Fecher, is a foremost financial CEO with an extensive ... president of lending and later chief operating officer at ... Fecher has led the Beavercreek-based Wright-Patt Credit Union that ...
Breaking Medicine News(10 mins):Health News:Colorado Non-Profit Foresight Ski Guides Seeking Applications for Blind and Visually Impaired Skiers and Guides for Vail Ski Season 2Health News:Push to Walk Participates in Macy’s Ninth Annual “Shop For A Cause” 2Health News:Push to Walk Participates in Macy’s Ninth Annual “Shop For A Cause” 3Health News:Tidewater Physical Therapy to Host Monthly Runner’s Injury Clinic at 3 Sports Glen Allen Location 2Health News:Tidewater Physical Therapy to Host Monthly Runner’s Injury Clinic at 3 Sports Glen Allen Location 3Health News:September Events: Regional Conference on Mesothelioma in Philadelphia 2Health News:September Events: Regional Conference on Mesothelioma in Philadelphia 3
... 9 Schering-Plough Corporation (NYSE: SGP ... Global Healthcare Conference in Miami, on Tuesday, March ... in various investor and employee communications related to ... and therefore, will not be able to attend ...
... Kidney Disease (CKD), which affects 20 million people, is ... U.S. and it is growing at a steady and ... the cost of managing CKD exceeds $32 billion in ... are at increased risk for developing CKD and kidney ...
... Co-Founded Father Martin,s Ashley Treatment Center in MarylandHAVRE DE ... Martin, S.S., noted authority and lecturer on alcoholism who ... Havre de Grace, MD, died today at his home ... for his lectures on alcoholism as a disease, delivered ...
... a birthday increases colorectal cancer screenings , ... Society for Gastrointestinal Endoscopy (ASGE) has created a birthday ... reminds recipients age 50 and over to get screened ... According to a recent study from researchers in Norway, ...
... 9 NJHA Corporate Services has partnered with ... offer training and consulting services to its member ... The deal comes on the heels of The ... directs healthcare facilities to establish a plan to ...
... value, lower transaction costs in healthcare industryDALLAS, March 9 ... document and payment processing services and solutions, will once ... to improve health costs, quality and access by serving ... Medical Banking Institute, to be held March 11-13 in ...
Cached Medicine News:Health News:IPRO Alerts New Yorkers to 'Silent' Killer; Chronic Kidney Disease Doubling Every Ten Years 2Health News:The Rev. Joseph C. Martin, Leading Authority on Alcoholism and Addiction Treatment, Dies at 84 2Health News:The Rev. Joseph C. Martin, Leading Authority on Alcoholism and Addiction Treatment, Dies at 84 3Health News:The Rev. Joseph C. Martin, Leading Authority on Alcoholism and Addiction Treatment, Dies at 84 4Health News:ASGE's Birthday e-Card Reminds Recipients to Get Screened for Colorectal Cancer! 2Health News:ASGE's Birthday e-Card Reminds Recipients to Get Screened for Colorectal Cancer! 3Health News:ASGE's Birthday e-Card Reminds Recipients to Get Screened for Colorectal Cancer! 4Health News:NJHA, McNamara and Associates Inc. Team Up to Provide Strategies for Controlling Workplace Violence 2Health News:BancTec Provides Thought Leadership at 7th Annual Medical Banking Institute 2Health News:BancTec Provides Thought Leadership at 7th Annual Medical Banking Institute 3
(Date:7/30/2014)... , July 30, 2014  There is still ... organization,s success. The 10th Annual Institute for Supply ... for Excellence in Supply Management is open for ... the understanding and importance of supply management by ... and best supply management practices.  Entries are due ...
(Date:7/30/2014)... 30, 2014 Advanced Photonix ® (NYSE MKT: ... 2014) financial results on Monday, August 11, 2014. A press ... close of the market and the Company will host a ... p.m. EDT on the same day. Participating in ... Director), Rob Risser (COO and Director), and ...
(Date:7/30/2014)... Mass., July 30, 2014  Hologic, Inc. (NASDAQ: ... third fiscal quarter ended June 28, 2014. ... Revenues increased 1.0% to $632.6 million, reflecting operational growth ... compared to the same period in the prior year. ... business segments. , Breast Health revenues grew 3.5%. ...
Breaking Medicine Technology:Institute for Supply Management, Michigan State University to recognize companies with excellent supply management practices 2Advanced Photonix to Webcast Fiscal 2015 First Quarter Earnings 2Hologic Announces Third Quarter Fiscal 2014 Operating Results 2Hologic Announces Third Quarter Fiscal 2014 Operating Results 3Hologic Announces Third Quarter Fiscal 2014 Operating Results 4Hologic Announces Third Quarter Fiscal 2014 Operating Results 5Hologic Announces Third Quarter Fiscal 2014 Operating Results 6Hologic Announces Third Quarter Fiscal 2014 Operating Results 7Hologic Announces Third Quarter Fiscal 2014 Operating Results 8Hologic Announces Third Quarter Fiscal 2014 Operating Results 9Hologic Announces Third Quarter Fiscal 2014 Operating Results 10Hologic Announces Third Quarter Fiscal 2014 Operating Results 11Hologic Announces Third Quarter Fiscal 2014 Operating Results 12Hologic Announces Third Quarter Fiscal 2014 Operating Results 13Hologic Announces Third Quarter Fiscal 2014 Operating Results 14Hologic Announces Third Quarter Fiscal 2014 Operating Results 15Hologic Announces Third Quarter Fiscal 2014 Operating Results 16Hologic Announces Third Quarter Fiscal 2014 Operating Results 17
... Reportlinker.com announces that a new market research ... Pharmaceuticals: Global Industry Guide ... Pharmaceuticals: Global Industry Guide is ... analysis covering the Pharmaceuticals industry. It includes ...
... 2012 Ampio Pharmaceuticals, Inc. (Nasdaq: AMPE ... three lead drugs (Zertane™ completed two phase ... licensing distribution of these drugs and engaged in further ... interim review of the first 50% of patients enrolled ...
Cached Medicine Technology:Pharmaceuticals: Global Industry Guide 2Pharmaceuticals: Global Industry Guide 3Pharmaceuticals: Global Industry Guide 4Pharmaceuticals: Global Industry Guide 5Pharmaceuticals: Global Industry Guide 6Pharmaceuticals: Global Industry Guide 7Pharmaceuticals: Global Industry Guide 8Pharmaceuticals: Global Industry Guide 9Pharmaceuticals: Global Industry Guide 10Pharmaceuticals: Global Industry Guide 11Pharmaceuticals: Global Industry Guide 12Pharmaceuticals: Global Industry Guide 13Pharmaceuticals: Global Industry Guide 14Pharmaceuticals: Global Industry Guide 15Ampio Announces Positive Preliminary Update on the Optina™ Clinical Trial to Treat Diabetic Macular Edema and Decision to Conclude the Study Ahead of Schedule 2Ampio Announces Positive Preliminary Update on the Optina™ Clinical Trial to Treat Diabetic Macular Edema and Decision to Conclude the Study Ahead of Schedule 3Ampio Announces Positive Preliminary Update on the Optina™ Clinical Trial to Treat Diabetic Macular Edema and Decision to Conclude the Study Ahead of Schedule 4
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: