Navigation Links
Gene variants linked to metabolic syndrome and HDL cholesterol levels
Date:6/17/2008

Humans have two copies of each chromosome. In this study, people who had the protective variant on only one of their copies of chromosome 7 were less susceptible to metabolic syndrome. But people with two copies of the variant, who were completely deficient in the CD36 protein, did not appear to be protected. They tended to have lower levels of HDL, the so-called good cholesterol.

"A bit less CD36 protein may improve your risk profile, but people need some CD36 function," Abumrad says. "It's like requiring a certain level of fat in the diet. Fatty acids are important for optimal function of many tissues from pancreatic beta cells to skeletal muscle to the heart but too much fat creates a problem."

Love-Gregory and Abumrad found that many variants influenced blood levels of HDL cholesterol. Now they are taking a closer look at the relationship between CD36 and HDL cholesterol. Higher levels of HDL normally are considered positive, but because changes in the CD36 gene seem to influence HDL, the researchers want to make sure that the HDL molecule isn't being altered in composition or function.

"We're going to follow up on the HDL component of the study," Love-Gregory says. "We're also going to look for additional variants in the promoter region of the gene that controls how the gene is regulated. And we're planning to look for evidence of these gene variants and their associations with HDL and the metabolic syndrome in other populations and ethnic groups."


'/>"/>

Contact: Jim Dryden
jdryden@wustl.edu
314-286-0110
Washington University School of Medicine
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Gene Variants Linked to Lung Cancer Identified
2. Gene Variants Can Predict Threat of Heart Disease
3. Hot flashes underreported and linked to forgetfulness
4. Poor sleep linked to suicidal behavior among children and adolescents with depressive episodes
5. Frequent self-cutting linked to risky sexual behavior in teens
6. Disturbed rest, activity linked to mortality in older men
7. Sleep Apnea Linked to Memory Loss
8. Normal sleep linked to successful aging
9. Memory loss linked to common sleep disorder
10. Common bowel problem linked to chili pepper pain receptor
11. Sleep problems linked to obesity, lower quality of life in school-aged children
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/25/2014)... BellasDress has launched its Christmas Sale, offering ... chosen their best-selling lace wedding dresses, vintage bridesmaid dresses ... , Now, BellasDress.com features popular women’s dresses, and ... prices. The business hopes everyone can have a memorable ... “All our elegant products are made with exquisite materials; ...
(Date:12/25/2014)... Dennis Thompson HealthDay Reporter ... sick children with complex chronic illnesses can receive effective, less ... home," with easy access to a team of dedicated health ... likely to become seriously ill and need either hospitalization or ... at an enhanced medical home clinic at the University of ...
(Date:12/25/2014)... tries its best to translate the experience of dress ... introduced its new collection of 2015 prom dresses, and ... prom outfits are guaranteed to contain the perfect designs ... designed for 2015. Anyone who wants to buy ... before Jan. 26, 2015, the deadline of the promotion. ...
(Date:12/25/2014)... (PRWEB) December 25, 2014 Each year ... and 2 million hospital admissions across the nation (according ... ). The CDC’s National Hospital Ambulatory Medical Care ... a survey conducted in 2010. They estimated that there ... that resulted in a primary diagnosis of broken bone ...
(Date:12/24/2014)... December 24, 2014 Connie Casad, MD, ... functional medicine advocate with 30 years of practice experience ... evaluate the health benefits of dietary detoxification. The second ... participants following excellent results from test patients who just ... to explain her interest in conducting the study, Dr. ...
Breaking Medicine News(10 mins):Health News:BellasDress.com’s Christmas Sale: Trendy Wedding Dresses With Big Discounts 2Health News:Coordinated Care Through 'Medical Home' Best for Chronically Ill Kids: Study 2Health News:Coordinated Care Through 'Medical Home' Best for Chronically Ill Kids: Study 3Health News:Angelweddingdress 2015 Prom Dresses Online Now 2Health News:Every Year Four Million Emergency Department Visits Result from Accidents Involving Bone Trauma 2Health News:Every Year Four Million Emergency Department Visits Result from Accidents Involving Bone Trauma 3Health News:Every Year Four Million Emergency Department Visits Result from Accidents Involving Bone Trauma 4Health News:Connie Casad, MD, Now Accepting Test Participants for January Dietary Detoxification Study 2Health News:Connie Casad, MD, Now Accepting Test Participants for January Dietary Detoxification Study 3
... 2009 U.S. Sales Up 191% - , , - Total Net ... Conference Call to be Held Today at 3:30 pm Central Time - ... (Amex: UPI ), a medical device company that develops, manufactures ... results for the fourth quarter and full year ended March 31, 2009. ...
... Mass., June 4 PLC Systems Inc. (OTC Bulletin Board: ... device-based technologies, today announced the appointment of Louis Brenner, M.D. ... Senior Vice President at AMAG Pharmaceuticals, Inc., fills the seat ... , , Dr. Brenner, 39, brings to the PLC ...
... volunteers who led more than one million people in March for Babies ... of Dimes raise urgently needed funds for programs that help moms and ... a premature child, I know firsthand the toll that premature birth can ... supporting the March of Dimes," says Sherri Shepherd , ...
... research that has suggested excess weight worsens disease , THURSDAY, ... may not worsen asthma, as many experts have thought, but ... manage the chronic condition. , Inhaled corticosteroids are the most ... with asthma, many of whom are overweight or obese. , ...
... (NYSE: CBM ) announced today that it has ... the Company that it is in compliance with the revised ... on April 14, 2009, the Company had failed to meet ... over a consecutive 30-day period and total shareholders, equity had ...
... night, the America,s Health Insurance Plans (AHIP) Foundation paid ... Group Health Cooperative of South Central Wisconsin, and L.A. ... designed to improve the health and environment of communities ... health plans of working with local partners in a ...
Cached Medicine News:Health News:Uroplasty Reports Fourth Quarter and Full Year Fiscal 2009 Results 2Health News:Uroplasty Reports Fourth Quarter and Full Year Fiscal 2009 Results 3Health News:Uroplasty Reports Fourth Quarter and Full Year Fiscal 2009 Results 4Health News:Uroplasty Reports Fourth Quarter and Full Year Fiscal 2009 Results 5Health News:Uroplasty Reports Fourth Quarter and Full Year Fiscal 2009 Results 6Health News:Uroplasty Reports Fourth Quarter and Full Year Fiscal 2009 Results 7Health News:Uroplasty Reports Fourth Quarter and Full Year Fiscal 2009 Results 8Health News:Uroplasty Reports Fourth Quarter and Full Year Fiscal 2009 Results 9Health News:Uroplasty Reports Fourth Quarter and Full Year Fiscal 2009 Results 10Health News:Uroplasty Reports Fourth Quarter and Full Year Fiscal 2009 Results 11Health News:PLC Systems Announces Appointment of Louis Brenner, M.D. to Board of Directors 2Health News:Celebrities Lead One Million Walkers and Urge Public to Support March for Babies(R) 2Health News:Celebrities Lead One Million Walkers and Urge Public to Support March for Babies(R) 3Health News:Obesity May Dampen Response to Asthma Meds 2Health News:AHIP Foundation Announces 2009 Community Leadership Awards 2
(Date:12/24/2014)... FARMINGTON, Conn. , Dec. 24, ... PTN), a biopharmaceutical company developing targeted, receptor-specific peptide ... unmet medical need and commercial potential, today announced ... of 2,050,000 shares of its common stock and ... its common stock.  Funds under the management of ...
(Date:12/24/2014)... Dec. 23, 2014 PuraMed BioScience®, Inc., (OTC ... (OTC) medicinal and healthcare products, announced it received the ... a hemp-based, advanced headache relief product, for planned distribution ... Colorado , Washington State ... With the MigraPure H Advanced headache relief gel formulation ...
(Date:12/24/2014)... , Dec. 23, 2014  Advanced Medical ... company engaged primarily in the development of brachytherapy ... applications, today announced that it has filed a ... and Drug Administration ("FDA") for marketing clearance for ... 513(f)(2) of the U.S. Food, Drug and Cosmetic ...
Breaking Medicine Technology:Palatin Completes $20 Million Equity and $10 Million Debt Financings 2Palatin Completes $20 Million Equity and $10 Million Debt Financings 3Palatin Completes $20 Million Equity and $10 Million Debt Financings 4PuraMed BioScience Nears Final Stages Needed for Distribution of MigraPure H 2PuraMed BioScience Nears Final Stages Needed for Distribution of MigraPure H 3Advanced Medical Isotope Corporation Files a "de novo" Submission for Y-90 RadioGel(TM) Device 2Advanced Medical Isotope Corporation Files a "de novo" Submission for Y-90 RadioGel(TM) Device 3
... e-MDs, a leading provider of electronic health records (EHRs), ... partner by the Medical Society of the State of ... to representing the medical profession as a whole and ... work with e-MDs to encourage and facilitate the adoption ...
... April 6, 2011 The American Journal of ... this month demonstrating continued clinical acceptance of  the Naviscan ... scanner.  The first study concluded that breast radiologists can ... PEM images after a 2-hour tutorial which can take ...
Cached Medicine Technology:e-MDs Selected by Medical Society of the State of New York 2e-MDs Selected by Medical Society of the State of New York 3Study Shows Positron Emission Mammography (PEM) is Easy for Breast Imagers to Learn Regardless of Experience 2
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: