Navigation Links
Gene variants linked to metabolic syndrome and HDL cholesterol levels
Date:6/17/2008

June 17, 2008 -- Nutrition researchers at Washington University School of Medicine in St. Louis have identified five common genetic variations that increase the risk of metabolic syndrome, a group of factors linked to heart disease and diabetes. Another variant they found appeared to protect against the condition.

People with metabolic syndrome have at least three of the following symptoms: abdominal obesity, high blood triglyceride levels, lower good cholesterol (HDL), elevated blood pressure and elevated fasting blood glucose. They are four times as likely to develop heart disease and at least seven times more likely to develop diabetes as individuals without metabolic syndrome.

The investigators, who report their findings in the June issue of the journal Human Molecular Genetics, looked for changes in the CD36 gene, which is located in a region of chromosome 7 that has been linked to metabolic syndrome in several genome-wide studies.

The researchers say linking changes in the CD36 gene to the risk for metabolic syndrome and abnormal levels of good cholesterol is important because as more people in the United States become obese, they also become susceptible to these problems. Better understanding of the relationships between obesity, the gene and disease risk may allow for earlier identification of individuals who are more susceptible to develop metabolic syndrome. Treatments such as medication or lifestyle changes could begin earlier, perhaps preventing or delaying future problems with diabetes or heart disease.

Senior investigator Nada A. Abumrad, Ph.D., the Dr. Robert C. Atkins Professor of Medicine and Obesity Research, first identified the CD36 protein in studies with mice. Her research has demonstrated that the protein facilitates the use of fatty acids for energy. CD36 is located on the surface of cells and distributed throughout many tissues, including fat cells, the digestive tract, heart and skeletal muscl
'/>"/>

Contact: Jim Dryden
jdryden@wustl.edu
314-286-0110
Washington University School of Medicine
Source:Eurekalert

0

GOOD

Page: 1 2 3

Related medicine news :

1. Gene Variants Linked to Lung Cancer Identified
2. Gene Variants Can Predict Threat of Heart Disease
3. Hot flashes underreported and linked to forgetfulness
4. Poor sleep linked to suicidal behavior among children and adolescents with depressive episodes
5. Frequent self-cutting linked to risky sexual behavior in teens
6. Disturbed rest, activity linked to mortality in older men
7. Sleep Apnea Linked to Memory Loss
8. Normal sleep linked to successful aging
9. Memory loss linked to common sleep disorder
10. Common bowel problem linked to chili pepper pain receptor
11. Sleep problems linked to obesity, lower quality of life in school-aged children
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/18/2013)... A new $119 million industry is taking ... is redefining the way consumers get their seafood. ... culinary chefs on the Emerald Coast panhandle of Northwest ... and the promising industry of aquaculture. , The word ... strive to fully partake in the effort, especially when ...
(Date:6/18/2013)... As Mirena lawsuit claims continue to ... report has revealed that that the IUD has been the ... (FDA) adverse event reports since coming on the market in ... Mirena users have reported device dislocation or migration to the ... uterine perforations due to Mirena.* , “We are not at ...
(Date:6/18/2013)... New York magazine named 145 physicians from ... list, up from 129 last year and more than any ... lists 52 additional doctors who serve at hospitals within Mount ... The “Best Doctors” issue, which this year features a total ... and is available online at http://www.nymag.com/bestdoctors . , “America ...
(Date:6/18/2013)... 2013 -- Lauren Sciences, a privately-held biotechnology company ... technology, announced today that it was independently recognized ... its V-Smart Platform, and selected as a Featured ... , The report, " Early Stage ... Companies ," features companies MCD Group independently selected ...
(Date:6/18/2013)... more likely to keep their scheduled medical appointments ... their physician listens, explains things clearly and knows them ... Hopkins research suggests. , "If people feel their doctor ... that doctor has their best interests at heart and ... study leader Tabor E. Flickinger, M.D., M.P.H., a fellow ...
Breaking Medicine News(10 mins):Health News:New $119 Million Industry Swimming Up the East Coast 2Health News:Mirena Lawsuit News: Bernstein Liebhard LLP Comments on Mounting Reports of Mirena Side Effects, Including Device Migration, Uterine Perforations 2Health News:Mirena Lawsuit News: Bernstein Liebhard LLP Comments on Mounting Reports of Mirena Side Effects, Including Device Migration, Uterine Perforations 3Health News:Mount Sinai Tops the List in New York Magazine’s 2013 “Best Doctors” Issue 2Health News:Mount Sinai Tops the List in New York Magazine’s 2013 “Best Doctors” Issue 3Health News:Respect may be the key to stopping patient 'no shows' 2
... increased risk for life-threatening cardiovascular diseases, people with type ... advised to monitor their blood sugar levels more than ... study. ,Researchers conducted a meta-analysis of 13 previously ... sugar levels and cardiovascular disease. Results showed that blood ...
... of glycosylated hemoglobin, or HA1c, may be an independent ... // and stroke, according to the new research. Two ... control and the development of heart disease and stroke. ... people, investigators found a 21-percent increase in cardiovascular events ...
... tends to be more severe and resistant to medical ... improvement in symptoms when a full range of medical ... patients with asthma were found to have a higher ... compared to patients without asthma. A higher proportion of ...
... used antibiotic, but new research suggests it could be ... study shows patients should not be given erythromycin along ... because it increases the risk of sudden death. ... is any association between the use of erythromycin and ...
... designed to educate parents about allergens and tobacco smoke ... say researchers .More than 900 children with ... least one indoor environmental allergen and lived in low-income ... areas suffer from the disease at a disproportionately high ...
... to a recent study researchers say the antidepressant ... symptoms of fibromyalgia in women . Duloxetine ... // norepinephrine, two of the brain’s neurotransmitters that ... chronic musculoskeletal disorder that is characterized by body ...
Cached Medicine News:
(Date:6/18/2013)... June 18, 2013  Decision Resources, one of ... pharmaceutical and healthcare issues, announces that its Market ... Middle East and ... the challenges and opportunities to gaining and maintaining ... comprising 24 countries. The countries covered by Market ...
(Date:6/18/2013)... , June 18, 2013 Today, Wall ... (NASDAQ: GILD ), Health Management Associates Inc. (NYSE: ... IDXX ), ISIS Pharmaceuticals Inc. (NASDAQ: ISIS ), ... these reports free of charge - including full price targets, ... Gilead Sciences, Inc. Research Report On ...
(Date:6/18/2013)... , June 18, 2013  Pro football player ... and professional family expert Jo Frost ... Mylan Specialty L.P., the fully integrated specialty pharmaceutical business ... raise awareness of this significant health problem. In recognition ... Food and Drug Administration (FDA) approval of EpiPen ® ...
Breaking Medicine Technology:Decision Resources' Market Access Tracker Now Covers the Middle East and Africa 2Decision Resources' Market Access Tracker Now Covers the Middle East and Africa 3Industry Shows a Healthy Pulse with Priority Reviews, Positive Results, New Testing Procedures, and Partnerships - Research Report on Gilead, Health Management, IDEXX, ISIS, and Trius Therapeutics 2Industry Shows a Healthy Pulse with Priority Reviews, Positive Results, New Testing Procedures, and Partnerships - Research Report on Gilead, Health Management, IDEXX, ISIS, and Trius Therapeutics 3Industry Shows a Healthy Pulse with Priority Reviews, Positive Results, New Testing Procedures, and Partnerships - Research Report on Gilead, Health Management, IDEXX, ISIS, and Trius Therapeutics 4Industry Shows a Healthy Pulse with Priority Reviews, Positive Results, New Testing Procedures, and Partnerships - Research Report on Gilead, Health Management, IDEXX, ISIS, and Trius Therapeutics 5Industry Shows a Healthy Pulse with Priority Reviews, Positive Results, New Testing Procedures, and Partnerships - Research Report on Gilead, Health Management, IDEXX, ISIS, and Trius Therapeutics 6Mylan Specialty L.P. Joins Forces with Adrian Peterson and Jo Frost to Launch Anaphylaxis Preparedness Campaign 2Mylan Specialty L.P. Joins Forces with Adrian Peterson and Jo Frost to Launch Anaphylaxis Preparedness Campaign 3Mylan Specialty L.P. Joins Forces with Adrian Peterson and Jo Frost to Launch Anaphylaxis Preparedness Campaign 4Mylan Specialty L.P. Joins Forces with Adrian Peterson and Jo Frost to Launch Anaphylaxis Preparedness Campaign 5Mylan Specialty L.P. Joins Forces with Adrian Peterson and Jo Frost to Launch Anaphylaxis Preparedness Campaign 6Mylan Specialty L.P. Joins Forces with Adrian Peterson and Jo Frost to Launch Anaphylaxis Preparedness Campaign 7Mylan Specialty L.P. Joins Forces with Adrian Peterson and Jo Frost to Launch Anaphylaxis Preparedness Campaign 8
... March 22 Royal Philips Electronics ( PHG, ... medical alert service.  This integrated solution offers an added ... medical alert service with automatic fall detection capabilities. Lifeline ... can automatically call for help if a fall is ...
... WALTHAM, Mass. , March 22 Interleukin Genetics, Inc. ... of the NYSE Amex LLC (the "Exchange") has granted the Company an ... Company will remain listed up to June 23, 2010 , subject ... progress towards the Company,s plan to regain compliance. , ...
Cached Medicine Technology:Philips Introduces Breakthrough Medical Alert Service That Helps Enable Continued Independence for Seniors by Improving Access to Help in the Event of a Fall 2Philips Introduces Breakthrough Medical Alert Service That Helps Enable Continued Independence for Seniors by Improving Access to Help in the Event of a Fall 3Philips Introduces Breakthrough Medical Alert Service That Helps Enable Continued Independence for Seniors by Improving Access to Help in the Event of a Fall 4Philips Introduces Breakthrough Medical Alert Service That Helps Enable Continued Independence for Seniors by Improving Access to Help in the Event of a Fall 5Philips Introduces Breakthrough Medical Alert Service That Helps Enable Continued Independence for Seniors by Improving Access to Help in the Event of a Fall 6NYSE Amex Provides Interleukin Genetics, Inc. Extension To Meet Continued Listing Standards 2NYSE Amex Provides Interleukin Genetics, Inc. Extension To Meet Continued Listing Standards 3
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: