Navigation Links
Gene that magnetically labels cells shows potential as imaging tool
Date:6/3/2008

Mammalian cells can produce tiny magnetic nuggets after the introduction of a single gene from bacteria, scientists have found. The gene MagA could become a valuable tool for tracking cells' movement through the body via magnetic resonance imaging (MRI), says Xiaoping Hu, PhD, professor of biomedical engineering at Emory University and the Georgia Institute of Technology.

"We have found a very simple way to make mammalian cells have a magnetic signature," says Hu, who is director of Emory's Biomedical Imaging Technology Center and a Georgia Research Alliance Eminent Scholar.

The results are published in the June issue of Magnetic Resonance in Medicine.

The gene MagA comes from magnetotactic bacteria, which can sense the Earth's magnetic field. It encodes a protein that transports dissolved iron across cell membranes. When put into animal cells, MagA triggers the accumulation of lumps of magnetite (iron oxide) a few nanometers wide, making the cells prominently visible under magnetic resonance imaging.

Although Hu's team tested MagA's effects in human kidney cells, Hu says it will probably be most useful in transgenic animals. He and his colleagues found that MagA appears to be nontoxic.

"MagA can be thought of as the equivalent of green fluorescent protein, but for magnetic resonance imaging," he says.

Scientists around the world use green fluorescent protein, originally found in jellyfish, to map the connections of the nervous system or follow the migration of stem cells around the body, for example. Hu says he anticipates that MagA could find similar applications, with the advantage that magnetic fields can penetrate tissues more easily than light.


'/>"/>

Contact: Holly Korschun
hkorsch@emory.edu
404-727-3990
Emory University
Source:Eurekalert

Page: 1

Related medicine news :

1. Prescription labels geared toward pharmacies, not patients
2. Lilly Announces Updates to the Zyprexa and Symbyax U.S. Labels
3. System of simplified, standardized dosing instructions for prescription drug labels proposed
4. System of Simplified, Standardized Dosing Instructions for Prescription Medication Container Labels Proposed at Sixth Annual National Health Communication Conference
5. Renaissance Health Publishing, LLC Warns the Public that ConsumerLab.com is Not Independent and Labels the CL Seal of Approval a Worthless, Paid-For Advertising Gimmick
6. Alcohol Awareness Month: Distilled Spirits Council Urges Government Support for Standard Drink Information on Labels
7. FDA Proposes New Drug Labels for Pregnant Women
8. Misys Wins Prestigious Gold Labels From SWIFT for Entire Trade Services Solutions Portfolio
9. Tumors use enzyme to recruit regulatory T-cells and suppress immune response
10. Brain cells work differently than previously thought
11. Embryonic Stem Cells Repair Human Heart
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/21/2017)... (PRWEB) , ... September 21, 2017 , ... Japanese Zen ... Yoga Mat Revolution” on 6th, 7th and 8th October at Miranda Kuo Gallery on ... mat art pieces, such as Zen Kodo mat. Wanderlust , one of the ...
(Date:9/21/2017)... Boulder, CO (PRWEB) , ... September 21, 2017 ... ... Education Interview of the Month, Lewis and Clark College Emeritus Professor of Education ... Associate Faith Boninger, co-author of Asleep at the Switch: Schoolhouse Commercialism, Privacy, ...
(Date:9/20/2017)... ... September 20, 2017 , ... ... voice for people who have kidney disease. The theme “Describe a positive decision ... stories. Entrants needed to meet only one qualification— to have been diagnosed ...
(Date:9/20/2017)... ... September 20, 2017 , ... Announced ... Aligner clinical and commercial support services market) has entered into an agreement on ... Australia. , The PGSD is the first private Dental School to launch ...
(Date:9/20/2017)... ... September 20, 2017 , ... The Honey Pot ... Vaginas.” The goal is to ignite conversation via social media and word-of-mouth regarding ... brand has declared September “Humans with Vaginas” month, releasing a video celebrating the ...
Breaking Medicine News(10 mins):
(Date:9/7/2017)... Ind. , Sept. 7, 2017  Zimmer Biomet ... in musculoskeletal healthcare, today announced that it will be ... Global Healthcare Conference at the Grand Hyatt hotel in ... 11, 2017 at 11:40 a.m. Eastern Time. ... via Zimmer Biomet,s Investor Relations website at http://investor.zimmerbiomet.com ...
(Date:9/6/2017)... Sept. 6, 2017 NeuroRx, a clinical stage biopharma ... and Behavior (ASIB), has been granted Fast Track status by ... of NRX-100 (ketamine HCl) followed by NRX-101 (D-cycloserine + lurasidone). ... trial of this sequential therapy targeting patients who are admitted ... ...
(Date:9/5/2017)... LONDON , Sept. 5, 2017  Just 18 ... Valid Insight is pleased to announce the appointment of ... Tammy Wynne , Dominic Jones-Phillips and ... from industry. ... a team of market access writers. She has over ...
Breaking Medicine Technology: