Navigation Links
Gene that magnetically labels cells shows potential as imaging tool
Date:6/3/2008

Mammalian cells can produce tiny magnetic nuggets after the introduction of a single gene from bacteria, scientists have found. The gene MagA could become a valuable tool for tracking cells' movement through the body via magnetic resonance imaging (MRI), says Xiaoping Hu, PhD, professor of biomedical engineering at Emory University and the Georgia Institute of Technology.

"We have found a very simple way to make mammalian cells have a magnetic signature," says Hu, who is director of Emory's Biomedical Imaging Technology Center and a Georgia Research Alliance Eminent Scholar.

The results are published in the June issue of Magnetic Resonance in Medicine.

The gene MagA comes from magnetotactic bacteria, which can sense the Earth's magnetic field. It encodes a protein that transports dissolved iron across cell membranes. When put into animal cells, MagA triggers the accumulation of lumps of magnetite (iron oxide) a few nanometers wide, making the cells prominently visible under magnetic resonance imaging.

Although Hu's team tested MagA's effects in human kidney cells, Hu says it will probably be most useful in transgenic animals. He and his colleagues found that MagA appears to be nontoxic.

"MagA can be thought of as the equivalent of green fluorescent protein, but for magnetic resonance imaging," he says.

Scientists around the world use green fluorescent protein, originally found in jellyfish, to map the connections of the nervous system or follow the migration of stem cells around the body, for example. Hu says he anticipates that MagA could find similar applications, with the advantage that magnetic fields can penetrate tissues more easily than light.


'/>"/>

Contact: Holly Korschun
hkorsch@emory.edu
404-727-3990
Emory University
Source:Eurekalert

Page: 1

Related medicine news :

1. Prescription labels geared toward pharmacies, not patients
2. Lilly Announces Updates to the Zyprexa and Symbyax U.S. Labels
3. System of simplified, standardized dosing instructions for prescription drug labels proposed
4. System of Simplified, Standardized Dosing Instructions for Prescription Medication Container Labels Proposed at Sixth Annual National Health Communication Conference
5. Renaissance Health Publishing, LLC Warns the Public that ConsumerLab.com is Not Independent and Labels the CL Seal of Approval a Worthless, Paid-For Advertising Gimmick
6. Alcohol Awareness Month: Distilled Spirits Council Urges Government Support for Standard Drink Information on Labels
7. FDA Proposes New Drug Labels for Pregnant Women
8. Misys Wins Prestigious Gold Labels From SWIFT for Entire Trade Services Solutions Portfolio
9. Tumors use enzyme to recruit regulatory T-cells and suppress immune response
10. Brain cells work differently than previously thought
11. Embryonic Stem Cells Repair Human Heart
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/9/2014)... researchers reveal that sudden, acute episodes of low back ... temperature, humidity, air pressure, wind direction and precipitation. Findings ... journal of the American College of Rheumatology (ACR), indicate ... with higher wind speed or wind gusts, but was ... Health Organization (WHO) nearly everyone experiences low back pain ...
(Date:7/9/2014)... the Perelman School of Medicine at the University of ... have received an $8 million grant from the National ... light therapy (PDT) in patients with malignant pleural mesothelioma, ... manifests itself in the lining of the lungs and ... grant will fund a clinical trial and additional studies ...
(Date:7/9/2014)... captures heretofore hidden ways that cells are regulated, scientists ... breast cancer cells more likely to metastasize. , What,s ... part by blocking two other proteins that are normally ... disease processes could have unexpected ties. , The ... Nature , points to the possibility of new ...
(Date:7/9/2014)... New findings from Fox Chase Cancer Center paint a ... subset of breast cancers that have spread to the ... Tumors that grow into the skin, regardless of size ... classified as stage III and called "locally advanced" ... of cancer, often with poor survival. Locally advanced breast ...
(Date:7/9/2014)... -- Researchers from The Miriam Hospital have found ... who are also depressed have difficulty sticking to ... particularly true for women, and screening and brief ... of treatment. The study and its findings are ... , Chronic obstructive pulmonary disease is a ...
Breaking Medicine News(10 mins):Health News:Low back pain? Don't blame the weather 2Health News:Penn mesothelioma program receives $8 million NCI grant 2Health News:Protein pushes breast cancer cells to metastasize 2Health News:Protein pushes breast cancer cells to metastasize 3Health News:Fox Chase researchers recommend updating the staging criteria for breast cancer diagnoses 2Health News:Fox Chase researchers recommend updating the staging criteria for breast cancer diagnoses 3Health News:Miriam Hospital study examines effect of depressed mood on pulmonary rehab completion 2
... line of defence in the threat of bio-terrorism according to ... international team of researchers from Cardiff University and University of ... well be an antidote to Bacillus anthracis more commonly know ... currently drink 165 million cups of tea, and the healing ...
... at Henry Ford Hospital today announced the start of ... international, multi-center clinical trial to explore an investigational treatment ... suffering with advanced emphysema. The study focuses on a ... in the lung for trapped air (one of the ...
... This release is available in French . ... by Universit Laval scientist Marc-Andr Sirard has identified genetic ... best chance of leading to successful pregnancy after in ... success rate of single embryo transfer and diminish the ...
... Angeles, March 12 --Combined positron emission tomography (PET) and ... more effective method to evaluate response to radiation therapy, ... study by researchers at the University of Southern California ... be published in the March issue of the journal ...
... and obesity training, state,s,largest Medicaid managed care plan now ... provide medical professionals the opportunity to become ... Well, Live Well program, CHARLESTON, W.Va., March 12 ... in the country in asthma prevalence,UniCare Health Plan of ...
... TSTF ) a national provider of healthcare and ... the Nasdaq Stock,Market that the Nasdaq Hearings Panel has ... Global Market pending the effectiveness of the,Company,s proposed reverse ... on February 7, 2008. The decision of the Panel ...
Cached Medicine News:Health News:Is a cup of tea really the answer to everything -- even anthrax? 2Health News:Henry Ford Hospital to study effectiveness of a new procedure that may help emphysema suffers 2Health News:Researchers develop a method to select eggs with the best chance of leading to successful pregnancy 2Health News:USC researchers find benefit for lymphoma patients in combined PET-CT scanning 2Health News:UniCare of West Virginia Providing Assistance for Asthma Education Training 2Health News:UniCare of West Virginia Providing Assistance for Asthma Education Training 3Health News:Nasdaq Hearings Panel Grants TeamStaff's Request for Continued Listing Subject to a Reverse Stock Split 2Health News:Nasdaq Hearings Panel Grants TeamStaff's Request for Continued Listing Subject to a Reverse Stock Split 3
(Date:1/15/2014)... the leading health care supply chain expertise, analytics and ... national contracts that expand its portfolio to provide hospital ... These include manufacturer product and service agreements, as well ... IT consulting support. New Novation agreements ...
(Date:1/15/2014)... , January 15, 2014 Shire plc (LSE: SHP, ... Office of Fair Trading (OFT) approval condition to the announced tender ... VPHM).   As a result of the waiver, the ... to complete the tender offer on January 24, 2014 following the ...
(Date:1/15/2014)... , Jan. 15, 2014  Manufacturers, suppliers and distributors ... able to protect their most important business assets, ... ) Because of the highly-competitive ... remains one of the most litigious industry sectors ...
Breaking Medicine Technology:New Novation Information Technology VAR Contracts Offer Significant Savings to Hospitals 2Shire Waives OFT Condition Relating to the Acquisition of ViroPharma Inc. 2Shire Waives OFT Condition Relating to the Acquisition of ViroPharma Inc. 3Intellectual Property Insurance for Medical-related Products and Services 2
Ophthalmic Nd Yag Laser with excellent quality optics for clear image and good laser delivery. Compact and light-weight for portability....
The compact size and portability of the Epic system makes it a cost-effective solution for single or multi-office use....
A conventional blue visibility-tinted daily-wear lens, custom made for astigmats with up to -3.00 D of cylinder requiring adds of up to +2.50 D....
A soft contact lens that lets presbyopes see clearly and comfortably at all distances , without the hassles of bifocals or reading glasses. Recommended for daily wear. Also approved for extended wear...
Medicine Products: