Navigation Links
Gene that magnetically labels cells shows potential as imaging tool
Date:6/3/2008

Mammalian cells can produce tiny magnetic nuggets after the introduction of a single gene from bacteria, scientists have found. The gene MagA could become a valuable tool for tracking cells' movement through the body via magnetic resonance imaging (MRI), says Xiaoping Hu, PhD, professor of biomedical engineering at Emory University and the Georgia Institute of Technology.

"We have found a very simple way to make mammalian cells have a magnetic signature," says Hu, who is director of Emory's Biomedical Imaging Technology Center and a Georgia Research Alliance Eminent Scholar.

The results are published in the June issue of Magnetic Resonance in Medicine.

The gene MagA comes from magnetotactic bacteria, which can sense the Earth's magnetic field. It encodes a protein that transports dissolved iron across cell membranes. When put into animal cells, MagA triggers the accumulation of lumps of magnetite (iron oxide) a few nanometers wide, making the cells prominently visible under magnetic resonance imaging.

Although Hu's team tested MagA's effects in human kidney cells, Hu says it will probably be most useful in transgenic animals. He and his colleagues found that MagA appears to be nontoxic.

"MagA can be thought of as the equivalent of green fluorescent protein, but for magnetic resonance imaging," he says.

Scientists around the world use green fluorescent protein, originally found in jellyfish, to map the connections of the nervous system or follow the migration of stem cells around the body, for example. Hu says he anticipates that MagA could find similar applications, with the advantage that magnetic fields can penetrate tissues more easily than light.


'/>"/>

Contact: Holly Korschun
hkorsch@emory.edu
404-727-3990
Emory University
Source:Eurekalert

Page: 1

Related medicine news :

1. Prescription labels geared toward pharmacies, not patients
2. Lilly Announces Updates to the Zyprexa and Symbyax U.S. Labels
3. System of simplified, standardized dosing instructions for prescription drug labels proposed
4. System of Simplified, Standardized Dosing Instructions for Prescription Medication Container Labels Proposed at Sixth Annual National Health Communication Conference
5. Renaissance Health Publishing, LLC Warns the Public that ConsumerLab.com is Not Independent and Labels the CL Seal of Approval a Worthless, Paid-For Advertising Gimmick
6. Alcohol Awareness Month: Distilled Spirits Council Urges Government Support for Standard Drink Information on Labels
7. FDA Proposes New Drug Labels for Pregnant Women
8. Misys Wins Prestigious Gold Labels From SWIFT for Entire Trade Services Solutions Portfolio
9. Tumors use enzyme to recruit regulatory T-cells and suppress immune response
10. Brain cells work differently than previously thought
11. Embryonic Stem Cells Repair Human Heart
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2017)... ... 2017 , ... Medical lab testing through hospitals and other traditional ... test will take days to arrive to the end customer, having to travel through ... their lab tests, bypassing the cost and delay of traditional means. Now all employees ...
(Date:1/21/2017)... ... ... Seamild, the largest manufacturer of oats in China, is now aiming at global business ... recognized globally as one of the healthiest cereals, XieQingkui, the founder of Seamild, strongly ... to sow the seed of good karma. Buddhism spirit featuring benevolence and sacrifice are ...
(Date:1/21/2017)... ... January 21, 2017 , ... Santa Rosa Orthopaedics ... Petaluma, located at 167 Lynch Creek Way. The Petaluma office features three comfortable ... and rehabilitation services and on-site x-ray services. Two multi-specialist orthopaedic surgeons ...
(Date:1/20/2017)... ... January 20, 2017 , ... A new partnership between Goodwill® and ... longer use or need, from clothes to couches to dressers and bicycles. Roadie — ... them to the nearest Goodwill donation center through February 28th. , “January is ...
(Date:1/20/2017)... ... ... Bionic Sports Nutrition LLC, an American company devoted to developing high-quality nutritional supplements for ... Show in Hilton Head, SC. , Bionic Sports Nutrition manufactures its entire line ... all clients at reasonable prices. At the ECRM trade show, it had a unique ...
Breaking Medicine News(10 mins):
(Date:1/21/2017)... Jan. 20, 2017 ARMO BioSciences, Inc., a ... on the Company,s lead investigational immuno-oncology drug AM0010 (PEGylated ... the American Society of Clinical Oncology (ASCO), taking place ... "AM0010 induces the expansion ... T cells in the blood and tumors of ...
(Date:1/21/2017)... -- Research and Markets has announced the addition of ... Route Of Administration, End User - Forecast to 2025" report ... ... a CAGR of around 7.8% over the next decade to reach ... analyzes the global markets for Advanced Drug Delivery across all the ...
(Date:1/20/2017)... -- Research and Markets has announced the addition ... BMP, BUN Creatinine, Electrolyte Testing, HbA1c Testing, Comprehensive Metabolic Panel, Liver ... - 2024" report to their offering. ... The global clinical laboratory testing market ... Introduction of innovative solutions on the grounds of maximum efficiency and ...
Breaking Medicine Technology: