Navigation Links
Gene that causes tumor disorder linked to increased breast cancer risk
Date:11/26/2012

New Johns Hopkins research showing a more than four-fold increase in the incidence of breast cancer in women with neurofibromatosis-1 (NF1) adds to growing evidence that women with this rare genetic disorder may benefit from early breast cancer screening with mammograms beginning at age 40, and manual breast exams as early as adolescence.

In a small study of 126 women with NF1 at the Johns Hopkins Comprehensive Neurofibromatosis Center, the Johns Hopkins scientists identified four cases of breast cancer. The study showed a four-fold increased risk for breast cancer in women with NF1 compared to the general population of women under the age of 50. NF1 is characterized by the uncontrolled growth of mostly non-cancerous tumors along the body's nerves, often resulting in pain and disfigurement.

Beyond their implications for breast cancer screening guidelines for women with NF1, the findings may also shed light on the origins and nature of breast cancer in those without the syndrome, the researchers say, because other recent studies suggest that some women without neurofibromatosis-1 had breast cancers fueled primarily by an NF1 mutation. A recent study, for example, described in the journal Nature, estimated that 3 percent of all breast cancers in the general population are caused by NF1 mutations that arise spontaneously.

"When we study rare populations intensively, we learn things that also may be factors in very common diseases, like breast cancer," says Jaishri Blakeley, M.D., an assistant professor of neurology, neurosurgery and oncology at the Johns Hopkins University School of Medicine, and leader of the new study described online in the American Journal of Medical Genetics. "What we learn from this population will help us learn more about the subtleties of different types of breast cancers."

The major implication of their study, Blakeley says, is the need for medical specialty societies to develop guidelines recogn
'/>"/>

Contact: Stephanie Desmon
sdesmon1@jhmi.edu
410-955-8665
Johns Hopkins Medicine
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Seattle Childrens Research Institute helps identify causes of sagittal craniosynostosis
2. Faulty development of immature brain cells causes hydrocephalus
3. LA BioMeds Dr. Richard Casaburi investigates causes of COPD
4. Smoking causes asthma in second generation offspring
5. Key discovered to how chemotherapy drug causes heart failure
6. Tracking environmental causes of good and bad health
7. Staying Home With Sick Kids Causes Job Worries for Parents: Survey
8. In obesity, a micro-RNA causes metabolic problems
9. War causes mental illness in soldiers
10. Unemployment causes more mental health problems among Somalis in London than in Minneapolis
11. Internet addiction -- Causes at the molecular level
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/26/2014)... Kansas (PRWEB) November 26, 2014 ... will showcase expanded capabilities at RSNA 2014 in ... access, manage and share diagnostic images, photos, videos ... to Perceptive’s booth #8107 will learn more about ... newly acquired technologies and partner initiatives – that ...
(Date:11/26/2014)... One of the most important and vital ... her life is choosing the ideal wedding dress and ... to purchase high quality outfits. Today, BellasDress.com has unveiled ... can pick their suitable bridesmaid gowns here at discount ... ladies look scintillating and highlight all their most beautiful ...
(Date:11/26/2014)... TUESDAY, Nov. 25, 2014 (HealthDay News) -- Vultures have ... bacteria they ingest when eating dead animals, researchers report. ... bacteria found on the faces and in the guts ... United States. On average, the faces of the vultures ... with 76 in their guts, the study found. ...
(Date:11/26/2014)... -- The number of emergency department visits in the United ... record 136 million in 2011, according to the U.S. Centers ... that fewer people were going to ERs with non-urgent medical ... care within two hours of arriving at the ER. In ... Sixty percent of patients arrived at the ER after ...
(Date:11/26/2014)... HealthDay Reporter TUESDAY, Nov. 25, 2014 ... Food and Drug Administration will have many restaurant chains posting ... to movie theater popcorn and ice cream parlor fare. ... home, often consuming less nutritious food and underestimating the calories ... Monday afternoon news conference. Although listing calorie counts ...
Breaking Medicine News(10 mins):Health News:Perceptive Software to Demonstrate New Medical Content Management Features and Capabilities at RSNA 2014 2Health News:Perceptive Software to Demonstrate New Medical Content Management Features and Capabilities at RSNA 2014 3Health News:Royal Blue Bridesmaid Dresses Now Are Available for Christmas at BellasDress.com 2Health News:ER Visits on the Rise, Study Reports 2Health News:Calorie Counts Mandated at Chain Restaurants, FDA Says 2Health News:Calorie Counts Mandated at Chain Restaurants, FDA Says 3
... CLEVELAND, Aug. 25 As part of Jani-King International, the world,s ... have been recognized as part of the Corporate and Regional Office ... The IBA selected Jani-King,s entry as the winner for 2009. ... countries, including first-time winners from Japan, New Zealand, and Poland, were ...
... , , , ... ., makers of the patented probiotic strain Ganeden BC30 (R), today announced ... a leading U.S. importer-producer of private label and branded Italian pasta. ... probiotic-enhanced pasta available to consumers. , , The ...
... , , LONDON, Aug. 25 ... of patients - and make the wound care market a billion ... when appropriate treatment is not provided. Market players in the wound ... on the patient, in order to be able to develop more ...
... MILWAUKEE, Aug. 25 Worries about the H1N1 virus haven,t ... Bradley Corporation, a leading manufacturer of commercial bathroom and locker room ... Washing Survey, 54 percent said they "wash their hands no more ... , , "We were extremely surprised by that ...
... , , NEW YORK, Aug. 25 babyUV/kidsUV inc. ... "kidsUV Surf Team" brand. This new line is geared towards older kids ... on display at the KIDShow Las Vegas from August 31 to September ... to expand into a growing market of concerned parents wanting to protect ...
... , , 5,622 Families ... MIAMI, Aug. 25 Miami-Dade County Mayor Alvarez has eliminated all ... 2009. The proposed would mean the total elimination of over $31 ... significant portion of the CBO cuts would apply to Institute for ...
Cached Medicine News:Health News:Jani-King Recognized as Best in Support by the International Business Awards 2Health News:Ganeden Biotech, Racconto Introduce First Probiotic Pasta Line 2Health News:Ganeden Biotech, Racconto Introduce First Probiotic Pasta Line 3Health News:A Wound that Does Not Heal: Frost & Sullivan Reveals the Impact of Chronic Ulcers on the European Healthcare System 2Health News:Despite H1N1 Flu Threat, Most Americans Haven't Increased Hand Washing 2Health News:babyUV/kidsUV inc. Introduces Its kidsUV Surf Team Line of Sun Protection Swim Wear 2Health News:Miami Dade Budget Cuts Leave Needy Families to Fend for Themselves 2
(Date:11/26/2014)... , Nov. 25, 2014  Array BioPharma ... announced that its Chief Executive Officer, ... following upcoming conferences.  The public is welcome ... on the Array BioPharma website:  www.arraybiopharma.com ... 2014Time:1:30 p.m.  Eastern Time Location: Palace Hotel, ...
(Date:11/26/2014)... -- Halozyme Therapeutics, Inc. (NASDAQ: HALO ) will ... New York on Wednesday, December 3, 2014 ... Helen Torley , President and Chief Executive Officer, will provide ... through the "Investors" section of Halozyme,s corporate website at ... 90 days following the event. To access the live webcast, ...
(Date:11/24/2014)... 2014 Juno Therapeutics today announced that ... the company,s JCAR015 chimeric antigen receptor product candidate. ... or refractory B-cell acute lymphoblastic leukemia and was ... Cancer Center, where Phase 1 clinical trials are ... is important news for patients who may benefit ...
Breaking Medicine Technology:Halozyme Therapeutics To Present At The Piper Jaffray Healthcare Conference 2Juno T Cell Therapy For Leukemia Granted FDA Breakthrough Therapy Designation 2Juno T Cell Therapy For Leukemia Granted FDA Breakthrough Therapy Designation 3
... , March 12 Ardea Biosciences, Inc. (Nasdaq: RDEA ) a biotechnology company focused ... today reported recent accomplishments, announced fourth quarter and full-year 2009 financial results and provided key upcoming clinical ... ... , ...
... PARK, Ill., March 11 The U.S. ... the supplemental new drug application (sNDA) of a new ... Depot (leuprolide acetate for depot suspension) ... cancer.  Palliative treatment helps to relieve symptoms associated with ...
Cached Medicine Technology:Ardea Biosciences Reports Recent Accomplishments; Provides 2010 Outlook; Announces Fourth Quarter and Full-Year 2009 Financial Results and 2010 Financial Guidance 2Ardea Biosciences Reports Recent Accomplishments; Provides 2010 Outlook; Announces Fourth Quarter and Full-Year 2009 Financial Results and 2010 Financial Guidance 3Ardea Biosciences Reports Recent Accomplishments; Provides 2010 Outlook; Announces Fourth Quarter and Full-Year 2009 Financial Results and 2010 Financial Guidance 4Ardea Biosciences Reports Recent Accomplishments; Provides 2010 Outlook; Announces Fourth Quarter and Full-Year 2009 Financial Results and 2010 Financial Guidance 5Ardea Biosciences Reports Recent Accomplishments; Provides 2010 Outlook; Announces Fourth Quarter and Full-Year 2009 Financial Results and 2010 Financial Guidance 6Ardea Biosciences Reports Recent Accomplishments; Provides 2010 Outlook; Announces Fourth Quarter and Full-Year 2009 Financial Results and 2010 Financial Guidance 7Ardea Biosciences Reports Recent Accomplishments; Provides 2010 Outlook; Announces Fourth Quarter and Full-Year 2009 Financial Results and 2010 Financial Guidance 8Ardea Biosciences Reports Recent Accomplishments; Provides 2010 Outlook; Announces Fourth Quarter and Full-Year 2009 Financial Results and 2010 Financial Guidance 9Ardea Biosciences Reports Recent Accomplishments; Provides 2010 Outlook; Announces Fourth Quarter and Full-Year 2009 Financial Results and 2010 Financial Guidance 10Ardea Biosciences Reports Recent Accomplishments; Provides 2010 Outlook; Announces Fourth Quarter and Full-Year 2009 Financial Results and 2010 Financial Guidance 11Abbott Seeks FDA Approval of a New Six-Month 45-mg Formulation of Lupron(R) Depot for the Palliative Treatment of Advanced Prostate Cancer 2Abbott Seeks FDA Approval of a New Six-Month 45-mg Formulation of Lupron(R) Depot for the Palliative Treatment of Advanced Prostate Cancer 3Abbott Seeks FDA Approval of a New Six-Month 45-mg Formulation of Lupron(R) Depot for the Palliative Treatment of Advanced Prostate Cancer 4Abbott Seeks FDA Approval of a New Six-Month 45-mg Formulation of Lupron(R) Depot for the Palliative Treatment of Advanced Prostate Cancer 5Abbott Seeks FDA Approval of a New Six-Month 45-mg Formulation of Lupron(R) Depot for the Palliative Treatment of Advanced Prostate Cancer 6Abbott Seeks FDA Approval of a New Six-Month 45-mg Formulation of Lupron(R) Depot for the Palliative Treatment of Advanced Prostate Cancer 7
... Surgical Thoracic Trocar consists of ... and a flexible sleeve which ... or laceration to internal structures. ... holes to secure it to ...
... believe that the trocar should be a ... precision and speeding the process. So we ... that meets the needs of the most ... - The only trocar that affords the ...
Operate with confidence. Autosuture is advancing the sate of both open and minimally invasive surgery by providing surgical tools that feel right, function right, and facilitate the right outcome eve...
Operate with confidence. Autosuture is advancing the sate of both open and minimally invasive surgery by providing surgical tools that feel right, function right, and facilitate the right outcome eve...
Medicine Products: