Navigation Links
Gene sequence that can make half of us fatter is discovered
Date:5/4/2008

A gene sequence linked to an expanding waist line, weight gain and a tendency to develop type 2 diabetes has been discovered as part of a study published today in the journal Nature Genetics.

The study also shows that the gene sequence is significantly more common in those with Indian Asian than European ancestry. The research, which was funded by the British Heart Foundation, could lead to better ways of treating obesity.

Scientists from Imperial College London and other international institutions have discovered that the sequence is associated with a 2cm expansion in waist circumference, a 2kg gain in weight, and a tendency to become resistant to insulin, which can lead to type 2 diabetes. The sequence is found in 50% of the UK population.

Until now, we have understood remarkably little about the genetic component of common problems linked with obesity, such as cardiovascular disease and diabetes, said Professor Jaspal Kooner, the papers senior author from the National Heart and Lung Institute at Imperial College London. Finding such a close association between a genetic sequence and significant physical effects is very important, especially when the sequence is found in half the population.

The study shows that the sequence is a third more common in those with Indian Asian than in those with European ancestry. This could provide a possible genetic explanation for the particularly high levels of obesity and insulin resistance in Indian Asians, who make up 25% of the worlds population, but who are expected to account for 40% of global cardiovascular disease by 2020.

The new gene sequence sits close to a gene called MC4R, which regulates energy levels in the body by influencing how much we eat and how much energy we expend or conserve. The researchers believe the sequence is involved in controlling the MC4R gene, which has also been implicated in rare forms of extreme childhood obesity.

Previous research
'/>"/>

Contact: Laura Gallagher
L.Gallagher@imperial.ac.uk
44-020-759-46702
Imperial College London
Source:Eurekalert

Page: 1 2

Related medicine news :

1. HIV denialists spread misinformation online -- consequences could be deadly; and more
2. Consequences of online HIV denial; and more
3. New AHIP Report Takes a Ten Year Look at the Unintended Consequences of State Efforts to Change the Insurance Market
4. Unanticipated consequences of health-care information technology
5. 454 Sequencing(TM): Science Paper Describes a Novel, Highly Efficient Method of Sequencing Ancient DNA; Sequences the Mitochondria of 10 Individual Mammoths to Prove It
6. Half-million-dollar DNA sequencer to boost genetic science research at UH
7. Baylor College of Medicine increases fleet of Roche Genome Sequencer FLX Systems to 10 instruments
8. Domestic cat genome sequenced
9. Photo: Scientists Complete Genome Sequence of Fungus Responsible for Dandruff, Skin Disorders
10. Design of patient tracking tools may have unintended consequences
11. Video Web Cast From IAFP Reveals the Consequences of Medicare Physician Payment Cuts
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/25/2014)... 26, 2014 2014 Deep ... Permeation Chromatography Industry” is a professional and ... China Gel Permeation Chromatography market. The report ... Gel Permeation Chromatography definition, classification, application, and ... overview. This research covers the international market ...
(Date:7/25/2014)... July 25, 2014 A federal judge ... in two DePuy Pinnacle hip lawsuits ( http://www.depuypinnacle-lawsuit.com/ ... the claims to go before a jury on September ... rendered on July 18th, U.S. District Judge Ed Kinkeade ... two Plaintiffs’ claims may proceed to trial against Johnson ...
(Date:7/25/2014)... Seniors are more easily distracted during thinking and memory ... "Almost any type of memory test administered reveals a ... study co-author Randi Martin, professor of psychology at Rice ... Martin said, this study shows that "environmental interference" has ... with younger adults. The study included 60 seniors, ...
(Date:7/25/2014)... As reported by People Magazine in the ... Shore and Getting Sober (7/15), one of the most ... spoken out to the public about his personal transformation. Now, ... Situation admits that moving on with his life was a ... other drugs in 2012 and even spent some time in ...
(Date:7/25/2014)... (PRWEB) July 25, 2014 AttorneyOne.com, a recognized ... latest information from the FDA on Ibuprofen and Oxcarbazepine ... that one lot of Ibuprofen and one lot of Oxcarbazepine ... due to mislabeled packaging. Oxcarbazepine is used for the treatment ... , The reason for the recall is that Lot ...
Breaking Medicine News(10 mins):Health News:2014 China & Global GPC Industry - Gel Permeation Chromatography Development Trends Now at DeepResearchReports.com 2Health News:2014 China & Global GPC Industry - Gel Permeation Chromatography Development Trends Now at DeepResearchReports.com 3Health News:First Federal DePuy Pinnacle Hip Lawsuits Headed for Trial, As Judge Denies Defense Motions For Dismissal, Summary Judgment, Bernstein Liebhard LLP Reports 2Health News:First Federal DePuy Pinnacle Hip Lawsuits Headed for Trial, As Judge Denies Defense Motions For Dismissal, Summary Judgment, Bernstein Liebhard LLP Reports 3Health News:First Federal DePuy Pinnacle Hip Lawsuits Headed for Trial, As Judge Denies Defense Motions For Dismissal, Summary Judgment, Bernstein Liebhard LLP Reports 4Health News:Distractions Seem More Troublesome With Age 2Health News:'The Situation' Celebrates 8 Months of Sobriety 2Health News:'The Situation' Celebrates 8 Months of Sobriety 3Health News:Ibuprofen and Oxcarbazepine Tablets Recalled: AttorneyOne Monitors and Keep Consumers Informed 2
... is hosting a,day-long program for survivors, families, caregivers and ... and improving quality of life. The program, sponsored ... place from 10 a.m. - 4:30 p.m., Friday, Nov. ... years, Henry Ford Hospital has been designated a Stroke,Center ...
... Jerusalem, Nov. 8, 2007 An Israeli-Jordanian-U.S. cooperative project ... the neighboring southern cities of Aqaba in Jordan and ... the Hebrew University of Jerusalem together with scientists from ... Desert Research Institute of Reno, Nevada, in the US. ...
... say , THURSDAY, Nov. 8 (HealthDay News) -- The areas ... a person can be absolutely certain of a past event ... say Duke University Medical Center researchers. , They used functional ... volunteers as they performed tests of both memory and false ...
... Best Recipe for Healthy Skin, NEW YORK, Nov. 8 ... applies to our overall health and nutrition, but how our ... the body, our skin can,benefit from the same nutrition we ... and other major organs. In fact, new research suggests,that eating ...
... of Stress on the Skin, Hair and ... ... final exams. A messy divorce. An unexpected surgery. What do,they all have in ... toll on a person physically and psychologically, it also,can lead to dermatologic problems, ...
... Students with Free Dental Screenings, ... Oral Health Education, MIAMI, Nov. 8 A national ... when more than 250 Coconut Grove,Elementary School students joined Colgate-Palmolive ... Miami for a lively game-show themed dental,challenge that featured music, ...
Cached Medicine News:Health News:'Beam of Light' is ray of hope for Israeli-Jordanian cooperation 2Health News:Brain Yields Clues to False Memories 2Health News:Taking Care of Your Skin Starts From Within 2Health News:Taking Care of Your Skin Starts From Within 3Health News:Taking Care of Your Skin Starts From Within 4Health News:Taking Care of Your Skin Starts From Within 5Health News:Feeling Stressed? 2Health News:Feeling Stressed? 3Health News:Feeling Stressed? 4Health News:"High School Musical's" Corbin Bleu Joins Colgate-Palmolive, United Way and Miami-Dade Elementary School Students for Dental Health Challenge 2Health News:"High School Musical's" Corbin Bleu Joins Colgate-Palmolive, United Way and Miami-Dade Elementary School Students for Dental Health Challenge 3
(Date:7/25/2014)... According to a new market ... Insulin Market (Rapid-Acting, Short-Acting, Intermediate-Acting, Long-Acting, Premixed, Modern and ... and Forecast (Value and Volume), 2013 - 2019", the ... in 2012 and is expected to grow at a ... USD 32.24 billion in 2019. Browse the ...
(Date:7/25/2014)... 25, 2014  IDEXX Laboratories, Inc. (NASDAQ: ... quarter of 2014 increased 11% versus the prior year ... for the second quarter of 2014 versus the prior ... in distributor inventory 2 . Earnings per diluted share ... 11% from the prior year period to $1.10."In the ...
(Date:7/25/2014)... 2014 Leading events organizer UBM Live ... the seventh year to São Paulo, Brazil ... 2014. The event will co-locate with Food Ingredients South America ... meeting point for the pharmaceutical industry.      (Logo: ... pharmaceutical sales are now exploring the South America ...
Breaking Medicine Technology:Global Insulin Market Expected to Reach USD 32.24 Billion Globally in 2019: Transparency Market Research 2Global Insulin Market Expected to Reach USD 32.24 Billion Globally in 2019: Transparency Market Research 3Global Insulin Market Expected to Reach USD 32.24 Billion Globally in 2019: Transparency Market Research 4IDEXX Laboratories Announces Second Quarter Results 2IDEXX Laboratories Announces Second Quarter Results 3IDEXX Laboratories Announces Second Quarter Results 4IDEXX Laboratories Announces Second Quarter Results 5IDEXX Laboratories Announces Second Quarter Results 6IDEXX Laboratories Announces Second Quarter Results 7IDEXX Laboratories Announces Second Quarter Results 8IDEXX Laboratories Announces Second Quarter Results 9IDEXX Laboratories Announces Second Quarter Results 10IDEXX Laboratories Announces Second Quarter Results 11IDEXX Laboratories Announces Second Quarter Results 12IDEXX Laboratories Announces Second Quarter Results 13IDEXX Laboratories Announces Second Quarter Results 14IDEXX Laboratories Announces Second Quarter Results 15IDEXX Laboratories Announces Second Quarter Results 16IDEXX Laboratories Announces Second Quarter Results 17IDEXX Laboratories Announces Second Quarter Results 18IDEXX Laboratories Announces Second Quarter Results 19IDEXX Laboratories Announces Second Quarter Results 20IDEXX Laboratories Announces Second Quarter Results 21IDEXX Laboratories Announces Second Quarter Results 22IDEXX Laboratories Announces Second Quarter Results 23IDEXX Laboratories Announces Second Quarter Results 24IDEXX Laboratories Announces Second Quarter Results 25IDEXX Laboratories Announces Second Quarter Results 26IDEXX Laboratories Announces Second Quarter Results 27IDEXX Laboratories Announces Second Quarter Results 28IDEXX Laboratories Announces Second Quarter Results 29IDEXX Laboratories Announces Second Quarter Results 30IDEXX Laboratories Announces Second Quarter Results 31IDEXX Laboratories Announces Second Quarter Results 32IDEXX Laboratories Announces Second Quarter Results 33
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: