Navigation Links
Gene links rare and unrelated cancers
Date:12/21/2011

or the development and behaviour of normal cells. The mutations we discovered do not totally destroy the function of DICER rather they warp itthe orchestra is still there but the conductor is drunk."

This finding is the third of a series of papers published recently in the New England Journal of Medicine in which the Ovarian Cancer Research team has used new genomic technologies to unlock the molecular basis of poorly understood types of ovarian cancer. This breakthrough is particularly pivotal because it could lead to solutions for treatment of more common cancers.

"Studying rare tumours not only is important for the patients and families who suffer from them but also provides unique opportunities to make discoveries critical to more common cancers both in terms of personalized medicine, but also in applying what we learn from how we manage rare diseases to more common and prevalent cancers," says Dr. Huntsman "The discovery of the DICER mutation in this varied group of rare tumours is the equivalent of finding not the needle in the haystack, but rather the same needle in many haystacks."

"This breakthrough will be of interest to both the clinical and the fundamental science communities," says Professor Phillip A. Sharp, Institute Professor at the Massachusetts Institute of Technology and co-winner of the 1993 Nobel Prize in Physiology and Medicine for the discovery of the structure of genes. "Huntsman, Morin and colleague's very exciting discovery of specific mutations in DICER, a factor essential for syntheses of small regulatory RNAs in ovarian and other human tumours, could lead to new approaches to treatment."

The research of the team is now working to determine the frequency and role of DICER mutations in other types of cancers and are expanding their collaboration to discover whether mutant DICER and pathways it controls can be modulated to treat both the rare cancers in which the mutations were discovered and more com
'/>"/>

Contact: Brian Lin
brian.lin@ubc.ca
604-822-2234
University of British Columbia
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. More Evidence Links Specific Genes to ADHD
2. Study Links Coffee to Lower Risk of Endometrial Cancer
3. EHJ paper underlines need for improved links between cardiologists and psychiatrists
4. Links to Mental Illness Seen in Fetal Brains: Study
5. Wayne State University study of heroin users to examine links between stress, drug use
6. More Evidence Links Tanning Beds to Higher Skin Cancer Risk
7. Study of US popular music links luxury alcohol brands with degrading sex
8. Study links pollutants to a 450 percent increase in risk of birth defects
9. Study Links New Dialysis Technology to Rise in Bleeding Risk
10. Penn team links schizophrenia genetics to disruption in how brain processes sound
11. Genetic Links Seen Between Bipolar Illness and Schizophrenia
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/3/2015)... ... July 03, 2015 , ... ... 2015 Annual Conference , the premiere continuing education and networking event ... at SeaWorld in Orlando, Florida. Speakers include the leading rheumatology experts in ...
(Date:7/3/2015)... , ... July 03, 2015 , ... ... took place on June 25, 2015 at 1:00pm. The Association welcomed speaker C. ... pertaining to injured bicyclists and practical points of investigating these types of cases. ...
(Date:7/3/2015)... ... July 03, 2015 , ... " Selfie on a Stick ... the latest and coolest technology products available to consumers. Amanda Forstrom, a technology expert ... selfie sticks are great for documenting memories. , Almost every smartphone has an incredibly ...
(Date:7/2/2015)... ... ... Enterprises, LLC. is pleased to announce the opening of its newest location in Dallas, Texas. ... premium frozen yogurt chain was listed as #22 on the Inc. 500 list of fastest ... Bachman Lake, is located at:, 3701 W. Northwest Highway, STE 430, Dallas, TX 75220 , ...
(Date:7/2/2015)... RI (PRWEB) , ... July 02, 2015 , ... Many ... safety in mind. That’s why Amica Insurance is sharing some tips to ... Commission (CPSC), approximately 230 people go to the emergency room daily with fireworks-related injuries ...
Breaking Medicine News(10 mins):Health News:RNS Announces Sessions and Speaker Lineup for the 2015 Annual Conference of the Rheumatology Nurses Society 2Health News:RNS Announces Sessions and Speaker Lineup for the 2015 Annual Conference of the Rheumatology Nurses Society 3Health News:Attorney from William Mattar Leads Discussion on Bicycle Accidents 2Health News:Learn How to Take Selfies like Kendall Jenner 2Health News:sweetFrog Opens 18th Location in the Lone Star State 2Health News:6 Fireworks Safety Tips from Amica Insurance 2
... By Steven Reinberg HealthDay Reporter , TUESDAY, ... called infective endocarditis, coupled with heart failure, heart valve surgery ... new study suggests. Infective endocarditis, an infection of ... valves, has been associated with a high risk of death. ...
... , TUESDAY, Nov. 22 (HealthDay News) -- ,Taking slightly ... the brand name Tylenol) over time can lead to an ... a new study. These "staggered overdoses" can occur when ... acetaminophen than they should, explained Dr. Kenneth Simpson, author of ...
... By Steven Reinberg HealthDay Reporter , TUESDAY, ... "energy" drinks skyrockets, so do related health problems, a ... almost 10 times more cases of reactions to beverages such ... to a new U.S. government report released Tuesday. More ...
... , TUESDAY, Nov. 22 (HealthDay News) -- Elderly black ... are much more likely to die in the hospital than ... risk of death was present even when black patients had ... researchers found. Diverticulitis occurs when small pouches in the ...
... discovered the novel protective role dendritic cells play in ... issue of journal Gastroenterology , shows dendritic cells ... dangerous swelling and inflammation of the pancreas gland. ... dendritic cells are needed in the pancreas for normal, ...
... News) --,College students tend to smoke when they are partying, ... are using social events and work as cues to remind ... an assistant professor of family and community medicine at the ... "This research is important for those working with college students ...
Cached Medicine News:Health News:Surgery May Boost Survival With Dangerous Heart Condition 2Health News:Surgery May Boost Survival With Dangerous Heart Condition 3Health News:Too Much Acetaminophen Over Time May Damage Liver 2Health News:ER Visits for Energy-Drink Ills Soar in U.S. 2Health News:ER Visits for Energy-Drink Ills Soar in U.S. 3Health News:More Blacks Die in Hospital After Diverticulitis Surgery 2Health News:Dendritic cells protect against acute pancreatitis 2Health News:Dendritic cells protect against acute pancreatitis 3Health News:College Students Smoke When They Party, Drink and Work 2
(Date:7/3/2015)... July 3, 2015  Obsidian HDS, the developer of ... service for the management of data on pharmaceutical and ... PharmaShine now includes the 2014 Open Payments General and ... on June 30. The data disclosed on Open Payments ... industry and providers totaling $6.49 billion and is the ...
(Date:7/2/2015)... , July 2, 2015 /PRNewswire/ - ESSA Pharma Inc. ... common shares have been approved for listing and trading on ... ESSA will begin trading on NASDAQ on July 9, ... Venture Exchange under the symbol "EPI". As a ... NASDAQ, each of the Company,s outstanding special warrants issued on ...
(Date:7/2/2015)... -- Releases of the genetically engineered Oxitec ... , , reduced the dengue mosquito population in an ... 95%, well below the modelled threshold for epidemic disease ... The journal PLOS Neglected Tropical Diseases published today the ... The results showed that in Juazeiro city, northeast ...
Breaking Medicine Technology:New Open Payments (Sunshine Act) Data Now Searchable on PharmaShine 2ESSA Pharma Inc. to Commence Trading on the NASDAQ Capital Market 2ESSA Pharma Inc. to Commence Trading on the NASDAQ Capital Market 3ESSA Pharma Inc. to Commence Trading on the NASDAQ Capital Market 4Oxitec Mosquito Works to Control Aedes aegypti in Dengue Hotspot 2Oxitec Mosquito Works to Control Aedes aegypti in Dengue Hotspot 3
... , HARBIN, China, Nov. 17 /PRNewswire-Asia-FirstCall/ ... Company") (Nasdaq: CSKI ), a,leading fully integrated pharmaceutical company in ... the third quarter,of 2009. , , Third Quarter ... to $43.2 million, -- Gross profit increased 44.8% ...
... Mass., Nov. 17 Decision Resources, one of the world,s ... finds that, driven by the continued dominance of opioids that ... cancer pain drug market will increase from $2.3 billion in ... France, Germany, Italy, Spain, the United Kingdom and Japan. , ...
Cached Medicine Technology:China Sky One Medical, Inc. Announces Record Third Quarter 2009 Results 2China Sky One Medical, Inc. Announces Record Third Quarter 2009 Results 3China Sky One Medical, Inc. Announces Record Third Quarter 2009 Results 4China Sky One Medical, Inc. Announces Record Third Quarter 2009 Results 5China Sky One Medical, Inc. Announces Record Third Quarter 2009 Results 6China Sky One Medical, Inc. Announces Record Third Quarter 2009 Results 7China Sky One Medical, Inc. Announces Record Third Quarter 2009 Results 8China Sky One Medical, Inc. Announces Record Third Quarter 2009 Results 9China Sky One Medical, Inc. Announces Record Third Quarter 2009 Results 10The Cancer Pain Drug Market, Driven by the Continued Dominance of Opioids, Will Increase From $2.3 Billion in 2008 to $3.7 Billion in 2018 2
... A lower cost alternative to Equalizers, the patented ... between two different vessel configurations. With the push ... be quickly and easily adjusted for test tubes ... Ergonomic Design for Unparalleled Comfort Pick one ...
... Exp Expandable Tip System A lower cost ... you to perform multi-sample transfers between two different ... a knob, tip spacing can be quickly and ... or 96 well plates. Ergonomic Design for ...
... Exp Expandable Tip System A ... System allows you to perform multi-sample transfers between ... pull of a knob, tip spacing can be ... microcentrifuge tubes) or 96 well plates. Ergonomic ...
... Expandable Tip System A lower cost alternative ... to perform multi-sample transfers between two different vessel ... knob, tip spacing can be quickly and easily ... 96 well plates. Ergonomic Design for Unparalleled ...
Medicine Products: