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Gene linked to increasingly common type of blood cancer
Date:7/20/2009

ada and Germany.

To reduce the potential for complicating factors, the more than 3,000 samples in the UC Berkeley-TGen study were from individuals who were HIV negative. Dr. Brown said future studies could include HIV-positive individuals, if enough samples were made available.

This pooled genome-wide association study used by the UC Berkeley-TGen investigators allowed them to screen more than 500,000 SNPs. The nearly 90 most significant SNPs were then genotyped to more closely examine their association with lymphoma.

This same pooling technique has been pioneered by TGen to screen for genes in other studies. Additional collaborations between UC Berkeley and TGen are planned.

"This study paves the way for more in-depth research into this type of cancer, which is increasingly affecting more people,'' said Dr. Jeffrey Trent, TGen's President and Research Director. "This study also builds an important collaborative relationship between TGen and UC Berkeley, one of the nation's top universities.''


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Contact: Steve Yozwiak
syozwiak@tgen.org
602-343-8704
The Translational Genomics Research Institute
Source:Eurekalert

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