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Gene expression improves the definition of a breast cancer subtype
Date:12/20/2012

Gene expression remains key

The method that unquestionably provides the most accurate and comprehensive information on each tumour are gene expression techniques. "Compared with histopathological data, tests based on gene expression techniques provide us with a more accurate molecular profile of each tumour and a more detailed estimate of the probability of relapse. The reason for this is that instead of determining three or four markers, we are assessing thousands of markers in one go. Having said that, these genomic techniques are not readily available in routine clinical practice," says Dr Aleix Prat, who was recently awarded the International Award for Breast Cancer Research for his work in bringing gene expression techniques closer to routine clinical practice. "In this study we evaluated a genomic test known as PAM50 which, in contrast to the other tests available, allow us to better characterise breast cancer at a biological level," continues Dr Prat. The VHIO is hoping to make this test available in 2013.


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Contact: Amanda Wren
awren@vhio.net
34-695-207-886
Vall dHebron Institute of Oncology
Source:Eurekalert

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