Navigation Links
Gene expression changes in nasal cells may help identify lung cancer in earliest stages
Date:5/15/2011

ATS 2011, DENVER A simple, minimally-invasive technique using cells from the interior of the nose could help clinicians detect lung cancer in its earliest and most treatable stages, according to a study conducted by researchers in Boston.

The study will be presented at the ATS 2011 International Conference.

"Our data suggests that evaluating gene expression changes in nasal cells found in the interior surface of the nose may serve as a non-invasive approach for the early detection of lung cancer in smokers," said study author Christina Anderlind, MD, Instructor of medicine at Boston University Medical Center.

Lung cancer is the most common cause of cancer mortality, with an average five-year survival rate of only 15 percent. However, survival rates are highly dependent upon how advanced the cancer is when detected.

"At an early stage, the five-year survival rate is 60 percent compared to only 2 percent at a late stage," Dr. Anderlind noted. "Despite this fact, early diagnosis is hard to achieve since the diagnostic tests currently available are highly invasive, such as open lung biopsy. We wanted to determine if a minimally invasive site like the nose could be used to diagnose cancer in its early stages, when there is a much greater chance of long-term survival."

For their study, the researchers collected nasal epithelial cells from thirty three smokers who were undergoing medically-indicated bronchoscopies for suspicion of lung cancer. Of these patients, eleven were found to have benign disease and twenty two had lung cancer. Brushings were taken from the right or left nostril and profiled on microarrays, a process that allows researchers to study gene expression changes.

"Microarrays allow us to get a detailed portrait of the expression levels of a large number of genes simultaneously, with our goal being to then sort through all these expression levels to find genes that differ in their expression between
'/>"/>

Contact: Keely Savoie
ksavoie@thoracic.org
212-315-8620
American Thoracic Society
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Personal Tragedy Reveals Untapped Artistic Expression / Family Business Memorializes Loved Ones with Compassion During Grieving
2. Gene expression test reduces need for invasive heart muscle biopsy
3. Spanish gene expression data promise targeting of anti-angiogenesis treatment
4. “You Are Very Pretty”, Says Myeexpert As It Releases A Book, Poetic Expressions, Dedicated To The Beauty of Women.
5. Expression of certain transporter proteins may predict resistance to drug therapy
6. New genetic analysis reveals principles of phenotypic expression
7. Infants hemodynamic responses to happy and angry facial expressions
8. Attention ladies and gentlemen: Courtship affects gene expression
9. Overexpression of repetitive DNA sequences discovered in common tumor cells
10. Oncometabolite linked with widespread alterations in gene expression
11. Gene expression to distinguish metastasizing from non-metastasizing head and neck cancers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2015)... May 23, 2015 Javon Bea ... the Sports Medicine and Rehabilitation Center, 557 N. Washington ... Mondays, June 1-July 20, 5:30-6:30 pm. , The 8-week ... and Laurie Finke, RN, BSN, who will offer training ... on nutrition, running mechanics and show selection and weekly ...
(Date:5/23/2015)... Baltimore, MD (PRWEB) May 23, 2015 Injury ... moratorium that has been passed by the Maryland legislature but ... , “The Maryland General Assembly passed HB 449 ... the Governor has not signed it into law. This bill ... 2017. Evidence is growing that demonstrates the danger of fracking ...
(Date:5/22/2015)... 22, 2015 Pioneer Millworks, the largest ... forefront of designing with reclaimed wood, introducing their latest ... Angeles, California. Their newest offerings, Vat 35, Reclaimed ... and color to America's largest design event. , “Designers, ... each show, anxious to see and feel the variety ...
(Date:5/22/2015)... Mountain Point Medical Center, a campus of Jordan Valley ... May 29, 2015 at 11 a.m., followed by a community ... center, set to officially open on June 1, 2015, is ... , “The opening of Mountain Point Medical Center is an ... said Kent Loosle, CEO of Mountain Point Medical Center. “Mountain ...
(Date:5/22/2015)... York, New York (PRWEB) May 22, 2015 ... http://www.xareltolawsuit2015.com/ ) filed on behalf of individuals who ... due to its use continue to move forward ... Louisiana. According to a Pretrial Order dated May ... the preservation of documents and electronically stored information. ...
Breaking Medicine News(10 mins):Health News:Baltimore Attorney Urges Governor Hogan to Sign the Fracking Moratorium Bill 2Health News:Baltimore Attorney Urges Governor Hogan to Sign the Fracking Moratorium Bill 3Health News:Pioneer Millworks to Reveal New Design Trends with Reclaimed Wood at Dwell on Design in LA 2Health News:Pioneer Millworks to Reveal New Design Trends with Reclaimed Wood at Dwell on Design in LA 3Health News:Mountain Point Medical Center, a Campus of Jordan Valley Medical Center, Hosts Ribbon Cutting Ceremony and Community Celebration on Friday, May 29, 2015 2Health News:Court Overseeing Federal Xarelto Lawsuits Establishes Procedures Governing Preservation of Documents, Electronically Stored Information 2Health News:Court Overseeing Federal Xarelto Lawsuits Establishes Procedures Governing Preservation of Documents, Electronically Stored Information 3Health News:Court Overseeing Federal Xarelto Lawsuits Establishes Procedures Governing Preservation of Documents, Electronically Stored Information 4
... cholesterol also control hypertension. // ,Researchers at Warwick ... using statins to reduce cholesterol get a bonus benefit from ... on blood pressure levels too. ,The researchers ... in blood pressure. The overall effect of the use of ...
... cases among the inmates of Tihar Jail in the national ... official report// said here Thursday. ,In 2006, 36 ... 12 in 2002, Minister of State for Home Affairs S. ... that regular health screening camps are being organised by the ...
... problem that has been long overlooked, President A.P.J. Abdul Kalam ... mentally ill women// who have no home. ,"While ... for themselves but also for their families, it becomes critical ... at the beginning of a two-day conference "Mental health - ...
... reminder of the penetration of kidney diseases worldwide. According to ... throes of kidney related ailments. ,Reputed nephrologists emphasized, ... detect the disease early. Kidney transplant and dialysis is simply ... ,Uncomplicated urine tests and blood tests can ...
... A new survey confirms that pulmonary/critical care physicians ... actively managing// their patients’ sleep problems. The survey ... Institute (ACCP-SI). It was found that most pulmonary/critical ... patterns of their female patients and are advising ...
... AMA has written to Health Minister, Tony Abbott, urging ... include funding guarantees// and performance benchmarks for medical training ... (AHCA) negotiations. ,The current AHCA expires ... soon. ,AMA President, Dr Mukesh Haikerwal, ...
Cached Medicine News:Health News:Nearly 2,500 Mentally Ill Women in Delhi are Destitute: Abdul Kalam 2Health News:Doctors Not Drowsy When Treating Women’s Sleep Issue 2Health News:Doctors Not Drowsy When Treating Women’s Sleep Issue 3
(Date:5/22/2015)... - More than fifty years ago, Thalidomide was approved by ... mothers. Tragically, Thalidomide caused serious and permanent physical and emotional ... has been provided to survivors over the years from sources ... in 1991 and settlements from drug companies. ... provide support, we have a clear moral obligation to help ...
(Date:5/22/2015)... 2015 The leading companies in the ... cardiac rhythm management device market dominate their competition, ... St. Jude Medical, Boston Scientific and Asahi Kasei ... segment. The healthcare market research publisher,s report, ... as a base year, providing forecasts for each ...
(Date:5/22/2015)... ROCKVILLE, Md. , May 22, 2015 /PRNewswire/ ... "RegeneRx") today announced a peer-reviewed publication of the ... study evaluating RGN-259 (RegeneRx,s preservative-free eye drops) for ... Inc.,s controlled adverse environment (CAE ® ) model.  ... and the results, which were previously disseminated by ...
Breaking Medicine Technology:Statement from Minister Ambrose on Thalidomide 2Statement from Minister Ambrose on Thalidomide 3Kalorama: Top Companies Dominate Cardiac Defibrillator Market 2Kalorama: Top Companies Dominate Cardiac Defibrillator Market 3Kalorama: Top Companies Dominate Cardiac Defibrillator Market 4Complete Data from RegeneRx Phase II Dry Eye Trial Published in Current Issue of Clinical Ophthalmology 2Complete Data from RegeneRx Phase II Dry Eye Trial Published in Current Issue of Clinical Ophthalmology 3Complete Data from RegeneRx Phase II Dry Eye Trial Published in Current Issue of Clinical Ophthalmology 4
... May 18, 2011 Ovid, part of ... the delivery of customizable electronic research information for the medical, scientific, ... OvidMD , the first clinical ... provides quick answers to clinical questions based on relevant full-text content ...
... FRANCISCO, May 18, 2011 Bayer HealthCare Pharmaceuticals, Inc. and ... that data evaluating the use of Nexavar® (sorafenib) tablets will ... Meeting of the American Society of Clinical Oncology (ASCO), June ... committed to researching the potential utility of sorafenib, and the ...
Cached Medicine Technology:Ovid Announces its First Clinical Tool, OvidMD, Designed for Physicians and Other Clinicians 2Ovid Announces its First Clinical Tool, OvidMD, Designed for Physicians and Other Clinicians 3Ovid Announces its First Clinical Tool, OvidMD, Designed for Physicians and Other Clinicians 4Nexavar Data to Be Presented at American Society of Clinical Oncology Annual Meeting 2Nexavar Data to Be Presented at American Society of Clinical Oncology Annual Meeting 3Nexavar Data to Be Presented at American Society of Clinical Oncology Annual Meeting 4Nexavar Data to Be Presented at American Society of Clinical Oncology Annual Meeting 5Nexavar Data to Be Presented at American Society of Clinical Oncology Annual Meeting 6Nexavar Data to Be Presented at American Society of Clinical Oncology Annual Meeting 7
...
Knot tier...
... Blitz Suture Retriever is for arthroscopic and open ... design eliminates complicated procedural steps. It may ... suture material and in conjunction with,anchors or screws ... small, curved needle tip permits the placement of ...
... RC Retractor comes with several ... superficial or deep muscle retraction. ... retraction in three different directions: ... The fiber optic light cable ...
Medicine Products: