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Gene combinations are found to be related to hip osteoporosis in postmenopausal women
Date:3/29/2011

This release is available in French and Spanish.

Women with osteoporosis in their hip suffer menopause two years earlier than healthy women, a study conducted at the University of Granada says. Additionally, although further study is required, researchers have found at least three genetic markers associated with osteoporosis in the hip in postmenopausal women.

Osteoporosis in the hip increases the risk of suffering fractures, which is extremely disabling for the patient, and represents a high cost for the health public system. The aim of this research study developed at the University of Granada was to understand the factors that increase the risk of developing osteoporosis. As a starting point, researchers took the relevance of genes in this disease, since 80% of bone formation is genetically determined.

For the purpose of this study, authors conducted a multi-center study involving five Spanish clinics. A sample of 2,000 patients was taken from the gynecology services of the partipating clinics. Detailed medical records were prepared of each patient including those risk factors known to intervene in osteoporosis of the hip. In addition, other factors that have not still been proved to intervene in osteoporosis as the Mediterranean diet were also studied. Blood collections were made to analyse genetic markers, and a densitrometry was done to study bone mineral density in spine and hip.

A Complex and Multifactor Disease This study was developed by Jess Carlos Presa Lorite at the Department of Obstetrics of the University of Granada and conducted by professors Nicols Mendoza Ladrn de Guevara, ngel Alejandro Santalla Hernndez y Alberto Salamanca Ballesteros. Scientists i
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Contact: Jess Carlos Presa Lorite
jpresalorite@hotmail.com
34-655-764-234
University of Granada
Source:Eurekalert  

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