Navigation Links
Gene Variation May Explain Some Female Infertility Cases
Date:5/17/2011

TUESDAY, May 17 (HealthDay News) -- A gene variation that causes faulty cholesterol regulation also appears to affect production of the pregnancy hormone progesterone and may be a reason why some women can't get pregnant, researchers say.

The Johns Hopkins University team looked at more than 200 infertile women who were undergoing in vitro fertilization (IVF) and identified nine who had the variation of the scavenger receptor class B type 1 (SCARB1) gene.

All nine women had low levels of progesterone, which plays a critical role in sustaining pregnancy in its earliest stages. These low levels of progesterone persisted even though the women were supplemented with progesterone as part of the IVF process. None of the women became pregnant after undergoing IVF.

This variation in the SCARB1 gene could be present in 8 percent to 13 percent of the population, according to study leader Dr. Annabelle Rodriguez, an associate professor of medicine at the Johns Hopkins University School of Medicine.

She and her colleagues also developed a simple blood test for the gene variation but noted there is no approved treatment for this type of infertility.

"Infertility is fairly common and a lot of the reasons for it are still unknown," Rodriguez said in a Hopkins news release. "Right now, the benefit of this research is in knowing that there might be a genetic reason for why some women have difficulty getting pregnant. In the future, we hope this knowledge can be translated into a cure for this type of infertility."

The study appears online in the journal Human Reproduction.

More information

The U.S. National Women's Health Information Center has more about female infertility.

-- Robert Preidt

SOURCE: Johns Hopkins Medicine, news release, May 16, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. 9-country study shows wide variations in how women with early breast cancer are treated
2. Three Genes Linked to Variations in Eye Color
3. Chromosomal variations found in early passage female embryonic stem cells
4. Regional variation in health-care spending and utilization higher in Medicare than private sector
5. Gene Variation Linked to Altruism
6. ICUROS study finds international variations in quality of life loss after fracture
7. Genetic variation cuts bladder cancer risk, protects chromosome tips
8. Genetic variation linked to longer telomeres and lower risk of bladder cancer
9. MicroRNA variations associated with earlier prostate cancer diagnosis in African-American men
10. Gene variation linked to infertility in women, study finds
11. Personal Injury Attorney David Perecman Explains the Possible Legal Consequences of Fatal 911 Operator Error in New York
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Gene Variation May Explain Some Female  Infertility Cases
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... Apple ... care services, staged a mock evacuation of the facility as part of a disaster ... Fire Department, Echo Hose EMS and Shelton City Emergency Manager, as well as the ...
(Date:10/13/2017)... , ... October 13, 2017 , ... Global Healthcare Management’s ... Alexandria Park in Milford, NJ. This free event, sponsored by Global Healthcare Management’s ... The fun run is geared towards children of all ages; it is a ...
(Date:10/13/2017)... ... October 13, 2017 , ... “The Journey: From the ... danger possible to save lost souls in the Philippines. “The Journey: From the Mountains ... a dedicated teacher of the Bible. She has taught all ages and currently teaches ...
(Date:10/12/2017)... ... October 12, 2017 , ... Planet Fitness, one of the largest and ... plans to open a flagship location in Covington, LA at 401 N. U.S. Highway ... store next to Office Depot in the Holiday Square shopping center. Its location allows ...
(Date:10/12/2017)... ... 2017 , ... Asante, a nationally recognized health system in ... existing home health joint venture through an agreement, effective October 1, 2017, to ... home health company with Asante, delivering clinically integrated care, for the past eight ...
Breaking Medicine News(10 mins):
(Date:10/10/2017)... -- NDS received FDA 510(k) clearance in May 2017 for its highly ... designed for endoscopy environments. An innovative secondary monitor solution, ZeroWire ... support the improvement of patient outcomes, procedural efficiency, and the lowering ... ... ...
(Date:10/4/2017)... 4, 2017  South Korean-based healthcare product Development Company ... "cprCUBE" on Kickstarter. The device will educate the user ... with better efficiency compared to the dated and pricey ... on efficacy of the compression for a more informed ... goal to raise $5,000. ...
(Date:10/2/2017)... 2017  Eli Lilly and Company (NYSE: ... third quarter of 2017 on Tuesday, October 24, 2017. ... day with the investment community and media to further ... call will begin at 9 a.m. Eastern time. Investors, ... webcast of the conference call through a link that ...
Breaking Medicine Technology: