Navigation Links
Gene Variant Tied to Severity of Drinking

Marker could be used to identify those at risk and tailor treatment methods

FRIDAY, Feb. 20 (HealthDay News) -- A variation in one gene may explain why some people are more heavily dependent on alcohol than are others.

University of Virginia Health System researchers linked the DNA sequencing of the SLC6A4 serotonin transporter gene to how many drinks a day people receiving help for alcohol dependency used to have. Serotonin, a brain chemical, previously had been found to help foster the pleasant feelings people get from drinking as well as personal preference and consumption of the beverage.

"Of the six variants examined in the study, we found that one variant at the 3' end of the gene showed a significant association with drinking intensity," study co-author Ming D. Li, professor of psychiatry and neurobehavioral sciences at UVA's School of Medicine, said in a news release from the university's health system. "Specifically, we found that individuals with the 'G' allele of this variant drink less than individuals with the 'T allele.' "

The findings, published in the February issue of Alcoholism: Clinical & Experimental Research, could help in tailoring treatment of alcoholism, study co-author Dr. Bankole Johnson, chairman of UVA's department of psychiatry and neurobehavioral sciences, said in the news release.

"A known genetic marker could be used to sub-type alcoholics and better determine treatment methods that can target specific underlying molecular mechanisms," Johnson said. "We hope to determine whether this particular genetic variant can be used as a marker to predict treatment outcomes for different serotonin agents."

More information

The U.S. Centers for Disease Control and Prevention has more about alcohol use and health.

-- Kevin McKeever

SOURCE: University of Virginia Health System, news release, Feb. 4, 2009

Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Gene Variant Raises Risk for Brain Cancer at Young Age
2. Gene Variant May Hike Womens Risk of Alzheimers
3. Biologist finds plant polymerases IV and V are really variants of Polymerase II
4. Gene Variant Tied to Smokers Risk of Lung Cancer
5. Genetic Variants Tied to Obesity
6. NEW Line of Pushbutton Pill Cases Launched by Variant Products
7. Newly found gene variants account for kidney diseases among African-Americans
8. Genetic variants associated with vitamin B12
9. APA resolves to play leading role in improving treatment for gender-variant people
10. Gene Variant May Contribute to Alzheimers Disease
11. Gene variants linked to metabolic syndrome and HDL cholesterol levels
Post Your Comments:
Related Image:
Gene Variant Tied to Severity of Drinking
(Date:6/25/2016)... ... June 25, 2016 , ... Austin residents seeking Mohs surgery services, can now ... and to Dr. Russell Peckham for medical and surgical dermatology. , Dr. Dorsey brings ... The selective fellowship in Mohs Micrographic Surgery completed by Dr. Dorsey was under the ...
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... ... athletes and non-athletes recover from injury. Recently, he has implemented orthobiologic procedures as ... City area —Johnson is one of the first doctors to perform the treatment. ...
(Date:6/24/2016)... ... 2016 , ... June 19, 2016 is World Sickle Cell Observance Day. In ... benefits of holistic treatments, Serenity Recovery Center of Marne, Michigan, has issued ... Sickle Cell Disease (SCD) is a disorder of the red blood cells, which can ...
(Date:6/24/2016)... ... 24, 2016 , ... Comfort Keepers® of San Diego, CA is excited to ... Recovery® program to drive cancer patients to and from their cancer treatments. Comfort ... quality of life and ongoing independence. Getting to and from medical treatments is ...
(Date:6/24/2016)... ... June 24, 2016 , ... Puradigm® ... Group (TGIG), has initiated cultivation and processing operations at its production facility, and ... Nevada. , Puradigm is the manufacturer of a complete system of proactive air ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)...   Pulmatrix, Inc ., (NASDAQ: PULM ... announced today that it was added to the Russell ... comprehensive set of U.S. and global equity indexes on ... milestone for Pulmatrix," said Chief Executive Officer Robert ... progress in developing drugs for crucial unmet medical needs, ...
(Date:6/23/2016)... June 23, 2016 Any dentist who has made ... the current process. Many of them do not even offer ... difficulties and high laboratory costs involved. And those who ARE ... at such a high cost that the majority of today,s ... Dr. Parsa Zadeh , founder of Dental Evolutions Inc. ...
(Date:6/23/2016)... June 23, 2016 Capricor ... ), a biotechnology company focused on the discovery, ... that patient enrollment in its ongoing randomized HOPE-Duchenne ... exceeded 50% of its 24-patient target. Capricor expects ... third quarter of 2016, and to report top ...
Breaking Medicine Technology: