Navigation Links
Gene Variant Tied to Severity of Drinking
Date:2/20/2009

Marker could be used to identify those at risk and tailor treatment methods

FRIDAY, Feb. 20 (HealthDay News) -- A variation in one gene may explain why some people are more heavily dependent on alcohol than are others.

University of Virginia Health System researchers linked the DNA sequencing of the SLC6A4 serotonin transporter gene to how many drinks a day people receiving help for alcohol dependency used to have. Serotonin, a brain chemical, previously had been found to help foster the pleasant feelings people get from drinking as well as personal preference and consumption of the beverage.

"Of the six variants examined in the study, we found that one variant at the 3' end of the gene showed a significant association with drinking intensity," study co-author Ming D. Li, professor of psychiatry and neurobehavioral sciences at UVA's School of Medicine, said in a news release from the university's health system. "Specifically, we found that individuals with the 'G' allele of this variant drink less than individuals with the 'T allele.' "

The findings, published in the February issue of Alcoholism: Clinical & Experimental Research, could help in tailoring treatment of alcoholism, study co-author Dr. Bankole Johnson, chairman of UVA's department of psychiatry and neurobehavioral sciences, said in the news release.

"A known genetic marker could be used to sub-type alcoholics and better determine treatment methods that can target specific underlying molecular mechanisms," Johnson said. "We hope to determine whether this particular genetic variant can be used as a marker to predict treatment outcomes for different serotonin agents."

More information

The U.S. Centers for Disease Control and Prevention has more about alcohol use and health.



-- Kevin McKeever



SOURCE: University of Virginia Health System, news release, Feb. 4, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Gene Variant Raises Risk for Brain Cancer at Young Age
2. Gene Variant May Hike Womens Risk of Alzheimers
3. Biologist finds plant polymerases IV and V are really variants of Polymerase II
4. Gene Variant Tied to Smokers Risk of Lung Cancer
5. Genetic Variants Tied to Obesity
6. NEW Line of Pushbutton Pill Cases Launched by Variant Products
7. Newly found gene variants account for kidney diseases among African-Americans
8. Genetic variants associated with vitamin B12
9. APA resolves to play leading role in improving treatment for gender-variant people
10. Gene Variant May Contribute to Alzheimers Disease
11. Gene variants linked to metabolic syndrome and HDL cholesterol levels
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Gene Variant Tied to Severity of Drinking
(Date:5/24/2017)... ... ... Dr. Manju R. Kejriwal, a leading Ohio dentist, is now welcoming new ... Dr. Kejriwal understands the emotional and financial toll traditional orthodontics can take on patients’ ... longer need to feel the esthetic effects of wires and brackets when they can ...
(Date:5/24/2017)... ... May 24, 2017 , ... ... female reproductive tract in which the endometrial lining of the uterus spreads ... and pain. Patients experiencing painful intercourse, painful periods, pelvic pain, or irregular ...
(Date:5/24/2017)... , ... May 24, 2017 , ... Rob Lowe is ... “Informed,” developed for Public Television. “Informed” brings the public important topics from all aspects ... treatment of the feet and issues surrounding feet and ankles. , Podiatry is essential ...
(Date:5/23/2017)... ... May 23, 2017 , ... MDLand International (MDLand), a leading ... that its iClinic V12.2 solution has achieved approval from National Center for Quality ... 2017 standards which emphasize team-based care with a significant focus on the care ...
(Date:5/23/2017)... ... , ... New England Journal Of Medicine Confirms Viability of Rory’s Regulations and ... Staunton Foundation Calls on Health & Human Services, Tom Price to Adopt Rory’s Regulations ... today reported on a new study released on May 21, 2017 in the New ...
Breaking Medicine News(10 mins):
(Date:5/22/2017)... MAITLAND, Fla. , May 22, 2017 /PRNewswire/ ... industry as a whole continue to make the ... evidence becomes increasingly important for ensuring positive patient ... Key industry stakeholders are shifting focus away from ... results and effects of long-term specialty drug therapy ...
(Date:5/15/2017)... May 15, 2017  Amy Baxter MD, chief executive ... in noninvasive pain relief, was awarded a 2017 Top ... Baxter was recognized at the MM&M Top 40 Healthcare ... City on May 10, 2017. The dinner ... industry go "beyond the pill."  "Innovation goes ...
(Date:5/11/2017)... , May 11, 2017  Thornhill Research Inc. ... been awarded an $8,049,024 USD five-year, firm-fixed-priced, indefinite-quantity/indefinite-delivery ... the Canadian Commercial Corporation (CCC) ( Ottawa, ... Systems to administer general anesthesia to patients requiring ... "The US Marine Corps have been a ...
Breaking Medicine Technology: