Navigation Links
Gene Variant Tied to Severity of Drinking
Date:2/20/2009

Marker could be used to identify those at risk and tailor treatment methods

FRIDAY, Feb. 20 (HealthDay News) -- A variation in one gene may explain why some people are more heavily dependent on alcohol than are others.

University of Virginia Health System researchers linked the DNA sequencing of the SLC6A4 serotonin transporter gene to how many drinks a day people receiving help for alcohol dependency used to have. Serotonin, a brain chemical, previously had been found to help foster the pleasant feelings people get from drinking as well as personal preference and consumption of the beverage.

"Of the six variants examined in the study, we found that one variant at the 3' end of the gene showed a significant association with drinking intensity," study co-author Ming D. Li, professor of psychiatry and neurobehavioral sciences at UVA's School of Medicine, said in a news release from the university's health system. "Specifically, we found that individuals with the 'G' allele of this variant drink less than individuals with the 'T allele.' "

The findings, published in the February issue of Alcoholism: Clinical & Experimental Research, could help in tailoring treatment of alcoholism, study co-author Dr. Bankole Johnson, chairman of UVA's department of psychiatry and neurobehavioral sciences, said in the news release.

"A known genetic marker could be used to sub-type alcoholics and better determine treatment methods that can target specific underlying molecular mechanisms," Johnson said. "We hope to determine whether this particular genetic variant can be used as a marker to predict treatment outcomes for different serotonin agents."

More information

The U.S. Centers for Disease Control and Prevention has more about alcohol use and health.



-- Kevin McKeever



SOURCE: University of Virginia Health System, news release, Feb. 4, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Gene Variant Raises Risk for Brain Cancer at Young Age
2. Gene Variant May Hike Womens Risk of Alzheimers
3. Biologist finds plant polymerases IV and V are really variants of Polymerase II
4. Gene Variant Tied to Smokers Risk of Lung Cancer
5. Genetic Variants Tied to Obesity
6. NEW Line of Pushbutton Pill Cases Launched by Variant Products
7. Newly found gene variants account for kidney diseases among African-Americans
8. Genetic variants associated with vitamin B12
9. APA resolves to play leading role in improving treatment for gender-variant people
10. Gene Variant May Contribute to Alzheimers Disease
11. Gene variants linked to metabolic syndrome and HDL cholesterol levels
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Gene Variant Tied to Severity of Drinking
(Date:5/6/2016)... UK (PRWEB) , ... May 06, 2016 , ... ... success in changing the way the pharmaceutical industry conducts clinical trials. This month Ibs ... most influential people in pharma, and he was honored as a Tech Disruptor by ...
(Date:5/6/2016)... ... May 06, 2016 , ... US Sports Camps has ... camp held at Oregon State University this summer. Employing world-class rugby figures, including former ... all skill levels with training on key fundamentals, match play, fitness and more. , ...
(Date:5/6/2016)... (PRWEB) , ... May 06, 2016 , ... ... feature AsedaSciences® in an upcoming episode, airing third quarter 2016, via Discovery Channel. ... vision of becoming a leader in optimized drug discovery through innovative cellular analysis. ...
(Date:5/6/2016)... ... May 06, 2016 , ... Online HR/benefits platforms offer a range of ... for traditional brokers and health plans. “ The Rapid Emergence of Online Benefits Firms: ... Information Services, Inc. (AIS), will offer an accurate picture of online benefits today, and ...
(Date:5/6/2016)... ... ... Canadian author Mark Black is a speaker, author, and life strategy coach who ... … with the help of his publisher Strategic Book Group and its subsidiary Publish ... bed waiting for a miracle: He needed a heart and double-lung transplant. From this came ...
Breaking Medicine News(10 mins):
(Date:5/4/2016)... 2016 Valeritas Holdings, Inc. (OTCQB: ... public offering (APO). This was accomplished via a reverse ... and a private placement of approximately 5 million shares ... Under the terms of the reverse merger, ... Inc. will trade on the OTC Markets under the ...
(Date:5/4/2016)... Research and Markets has ... Keratosis Market and Competitive Landscape Highlights - ...      (Logo: http://photos.prnewswire.com/prnh/20160330/349511LOGO ) , ... Highlights 2016, provides comprehensive insights into Actinic ... Keratosis market valuations and forecast, Actinic Keratosis ...
(Date:5/3/2016)... Research and Markets has announced ... Therapy Market Outlook 2020" report to their offering. ... ,Recombinant technology has improved significantly in past years due ... in coming years. Many cancer drugs have been developed ... are also expected to be developed with its help. ...
Breaking Medicine Technology: