Navigation Links
Gene Variant Tied to Schizophrenia

Discovery advances search for better treatments, experts say,,,,

FRIDAY, April 10 (HealthDay News) -- U.S. researchers say they've spotted a gene variant that may raise the risk of schizophrenia in some people, a finding that may lead to new drug treatments.

The study involved a genetic analysis of 24 Canadian families that had multiple members with schizophrenia. A functional DNA change that increases gene expression was found in a gene called NOS1AP, said Dr. Linda Brzustowicz, a professor of genetics at Rutgers University in New Jersey, and colleagues.

The findings, published in the April issue of the American Journal of Psychiatry, echo previous research that found increased expression of NOS1AP in the brains of people with schizophrenia.

Identifying this altered gene is an important step in learning more about schizophrenia, but much more research into other causes is required, Brzustowicz said. She noted that schizophrenia is not a single-gene disorder and there are environmental factors that are also important.

"It's not as though, if you have this altered gene, you will get the disease," she said in a Rutgers news release.

More than 40 percent of people in the general population have the gene variant, but only 1 percent have schizophrenia, and not all of those with the illness have the altered gene, Brzustowicz noted. But she added that the frequency of the altered gene is higher among people with schizophrenia than in the general population. For example, 55 percent of the schizophrenia patients in this study had the gene variant.

More information

Mental Health America has more about schizophrenia.

-- Robert Preidt

SOURCE: Rutgers, news release, April 7, 2009

Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. New risk variant for atopic dermatitis identified
2. Study IDs Gene Variants Tied to Sudden Cardiac Death
3. Gene Variant Tied to Cocaine-Induced Paranoia
4. Gene Variant Allies Autism, Gastrointestinal Woes
5. Gene Variant Raises Risk of Uterine Fibroids
6. Gene Variant Tied to Severity of Drinking
7. Gene Variant Raises Risk for Brain Cancer at Young Age
8. Gene Variant May Hike Womens Risk of Alzheimers
9. Biologist finds plant polymerases IV and V are really variants of Polymerase II
10. Gene Variant Tied to Smokers Risk of Lung Cancer
11. Genetic Variants Tied to Obesity
Post Your Comments:
Related Image:
Gene Variant Tied to Schizophrenia
(Date:11/27/2015)... ... 2015 , ... MPWH, the No.1 Herpes-only dating community in the world, revealed that over 50% ... More than 3.7 billion people under the age of 50 – or 67% of the ... first global estimates of HSV-1 infection . , "The data shocks us highly!" said ...
(Date:11/27/2015)... DE (PRWEB) , ... November 27, 2015 , ... ... member of the well-respected Microsoft Dynamics SL User Group (MSDSLUG). Recognized as Microsoft’s ... an independent group of Microsoft Dynamics SL software users, partners, industry experts and ...
(Date:11/27/2015)... ... November 27, 2015 , ... The moment you stop ... not only fulfilling the needs of advisers and clients but going above and ... providing top-tier customer service. However, there's always room for improvement, which is why ...
(Date:11/27/2015)... ... ... CBD College is proud to announce that on November 20th, ... its Diagnostic Medical Sonography program. CBD College is honored to join this very short ... universities in the state of California make the cut. CBD College is officially the ...
(Date:11/27/2015)... , ... November 27, 2015 , ... Dr. Thomas ... Associates, Inc. and Dr. Tucker Bierbaum with Emergency Medicine at St., Joseph ... that both STEMI and Sepsis conditions present in similar ways and require time-critical intervention ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... 2015 Research and Markets ( ... "2016 Future Horizons and Growth Strategies in the ... Country Segment Forecasts, Competitive Intelligence, Emerging Opportunities" ... --> --> This new 247-page ... therapeutic drug monitoring market, including emerging tests, technologies, ...
(Date:11/26/2015)... 2015 --> ... potential att använda SyMRI för att hitta ... patienter med multipel skleros (MS) eller hjärntumörmetastaser ... AB för att kunna använda SyMRI Research ... SyMRI kan man generera flera konstrastbilder från ...
(Date:11/26/2015)... , November 26, 2015 ... the "Self Administration of High Viscosity Drugs" ... ) has announced the addition of the ... report to their offering. --> Research ... addition of the "Self Administration of High ...
Breaking Medicine Technology: