Navigation Links
Gene Variant Tied to Schizophrenia
Date:4/11/2009

Discovery advances search for better treatments, experts say,,,,

FRIDAY, April 10 (HealthDay News) -- U.S. researchers say they've spotted a gene variant that may raise the risk of schizophrenia in some people, a finding that may lead to new drug treatments.

The study involved a genetic analysis of 24 Canadian families that had multiple members with schizophrenia. A functional DNA change that increases gene expression was found in a gene called NOS1AP, said Dr. Linda Brzustowicz, a professor of genetics at Rutgers University in New Jersey, and colleagues.

The findings, published in the April issue of the American Journal of Psychiatry, echo previous research that found increased expression of NOS1AP in the brains of people with schizophrenia.

Identifying this altered gene is an important step in learning more about schizophrenia, but much more research into other causes is required, Brzustowicz said. She noted that schizophrenia is not a single-gene disorder and there are environmental factors that are also important.

"It's not as though, if you have this altered gene, you will get the disease," she said in a Rutgers news release.

More than 40 percent of people in the general population have the gene variant, but only 1 percent have schizophrenia, and not all of those with the illness have the altered gene, Brzustowicz noted. But she added that the frequency of the altered gene is higher among people with schizophrenia than in the general population. For example, 55 percent of the schizophrenia patients in this study had the gene variant.

More information

Mental Health America has more about schizophrenia.



-- Robert Preidt



SOURCE: Rutgers, news release, April 7, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. New risk variant for atopic dermatitis identified
2. Study IDs Gene Variants Tied to Sudden Cardiac Death
3. Gene Variant Tied to Cocaine-Induced Paranoia
4. Gene Variant Allies Autism, Gastrointestinal Woes
5. Gene Variant Raises Risk of Uterine Fibroids
6. Gene Variant Tied to Severity of Drinking
7. Gene Variant Raises Risk for Brain Cancer at Young Age
8. Gene Variant May Hike Womens Risk of Alzheimers
9. Biologist finds plant polymerases IV and V are really variants of Polymerase II
10. Gene Variant Tied to Smokers Risk of Lung Cancer
11. Genetic Variants Tied to Obesity
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Gene Variant Tied to Schizophrenia
(Date:10/13/2017)... ... 13, 2017 , ... Ellevate Network, the leading network for professional women, brought ... gender equality at their inaugural Summit in New York City in June. The event ... audience of over 3 million. To watch the Mobilize Women video, click here ...
(Date:10/13/2017)... ... October 13, 2017 , ... Talented host, actor Rob Lowe, ... in a new episode of "Success Files," which is an award-winning educational program ... investigates each subject in-depth with passion and integrity. , Sciatica occurs when the ...
(Date:10/13/2017)... ... 2017 , ... “America On The Brink”: the Christian history of the United ... the creation of published author, William Nowers. Captain Nowers and his wife, Millie, ... spent thirty years in the Navy. Following his career as a naval aviator ...
(Date:10/12/2017)... ... , ... Planet Fitness, one of the largest and fastest growing franchisors and ... flagship location in Covington, LA at 401 N. U.S. Highway 190, in January of ... Depot in the Holiday Square shopping center. Its location allows it to serve both ...
(Date:10/12/2017)... ... ... The American College of Medical Informatics (ACMI) will present the 2017 Morris ... of AMIA’s Annual Symposium in Washington, D.C. AMIA’s Annual Symposium is taking ... in the field of medical informatics, this prestigious award is presented to an individual ...
Breaking Medicine News(10 mins):
(Date:9/22/2017)... AVACEN Medical (AVACEN) announced that its CE-Marked ... those with the widespread pain associated with fibromyalgia in ... Essex, England commented, "I had ... no sleep at all, tremendous pain, with every movement ... [the AVACEN 100] enough, how this has and is ...
(Date:9/19/2017)... Sept. 19, 2017   ZirMed Inc ., a recognized ... announced that it has been ranked #1 by its users ... Rankings 2017 User Survey. ZirMed was recognized as the ... hospitals and medical centers over 200 beds and holds one ... technology user survey history. ...
(Date:9/18/2017)... 2017 EpiVax, Inc. ("EpiVax") a ... immune engineering, today announced a new NIH-funded ... ... and presents a challenge for traditional flu ... be effective. Using state-of-the-art bioinformatics and molecular modeling methods, ...
Breaking Medicine Technology: