Navigation Links
Gene Variant Tied to More Aggressive Prostate Cancer
Date:12/11/2007

Men with differing version of tumor suppressor appear at increased risk, researchers say

TUESDAY, Dec. 11 (HealthDay News) -- Men with a variant in the tumor suppressor gene DAB2IP may have an increased risk of aggressive prostate cancer, say researchers who examined genetic clues in Swedish and American men with and without the disease.

The researchers identified a single nucleotide polymorphism (SNP) -- a single base change in DNA -- located in the DAB2IP gene that was associated with aggressive prostate cancer in European and African-American men.

"Our study is among the first to report the presence of a potentially important prostate cancer aggressiveness locus. However, we cannot rule out the possibility of false-positive association. This report is intended to stimulate the conduct of additional confirmation studies for a gene that has strong statistical support and biologic relevance as a tumor suppressor gene," wrote Dr. Jianfeng Xu, of Wake Forest University School of Medicine in Winston-Salem, N.C., and colleagues.

The study was published online Dec. 11 in the Journal of the National Cancer Institute.

Previous studies have offered evidence that genetics play a role in prostate cancer. This has led researchers to suspect there are genetic variants that put some men at increased risk for the disease.

More information

The American Cancer Society details prostate cancer risk factors.



-- Robert Preidt



SOURCE: Journal of the National Cancer Institute, news release, Dec. 11, 2007


'/>"/>
Copyright©2007 ScoutNews,LLC.
All rights reserved

Page: 1

Related medicine news :

1. Scientists demonstate link between genetic variant and effectiveness of smoking cessation meds
2. Scientists discover genetic variant associated with prostate cancer in African Americans
3. Gene Variant Doubles Risk of Prostate Cancer in Black Men
4. Frequent Prostate Screens Fail to Improve Aggressive Cancer Diagnoses
5. Coalition for Pulmonary Fibrosis Launches Aggressive Ad Campaign Directed at United States Congress
6. AWT Management Announce Aggressive Growth and Acquisition Strategy
7. Novel strategy under study for aggressive leukemia
8. Prostate cancer more likely to return in blacks than whites, but the disease is not more aggressive
9. Mayo Clinic tests novel vaccine for aggressive brain tumors
10. Aggressively Treating Cardiac Risk Factors May Reverse Ischemia
11. Breast cancer is more aggressive in African-American women
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... (PRWEB) , ... June 26, 2016 , ... PawPaws ... a new product that was developed to enhance the health of felines. The formula ... , The two main herbs in the PawPaws Cat Kidney Support Supplement ...
(Date:6/25/2016)... ... June 25, 2016 , ... Austin residents seeking Mohs surgery services, ... Mohs Surgery and to Dr. Russell Peckham for medical and surgical dermatology. , Dr. ... skin cancer. The selective fellowship in Mohs Micrographic Surgery completed by Dr. Dorsey was ...
(Date:6/25/2016)... ... June 25, 2016 , ... As a lifelong Southern Californian, ... and his M.D from the David Geffen School of Medicine at UCLA. He trained ... Angeles to complete his fellowship in hematology/oncology at the UCLA-Olive View-Cedars Sinai program where ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... A recent ... that most people are unfamiliar with. The article goes on to state that individuals ... also many of these less common operations such as calf and cheek reduction. The ...
(Date:6/24/2016)... ... June 24, 2016 , ... The Pulmonary Hypertension Association ... it will receive two significant new grants to support its work to advance ... 25th anniversary by recognizing patients, medical professionals and scientists for their work in ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... INDIANAPOLIS , June 23, 2016 If ... Leaders Scholarship is any indication, the future is in ... at www.diabetesscholars.org by the Diabetes Scholars Foundation ... the way of academic and community service excellence. ... since 2012, and continues to advocate for people with ...
(Date:6/23/2016)... June 23, 2016 Revolutionary technology ... Oticon , industry leaders in advanced audiology and ... Oticon Opn ™, the world,s first internet connected ... for IoT devices.      (Photo: http://photos.prnewswire.com/prnh/20160622/382240 ... a number of ,world firsts,: , TwinLink™ ...
(Date:6/23/2016)... Pa. , June 23, 2016 The ... in an outpatient dialysis facility.  Treatments are usually 3 ... 6 hours per visit, including travel time, equipment preparation ... a patient, but especially grueling for patients who are ... of a skilled nursing and rehabilitation centers for some ...
Breaking Medicine Technology: