Navigation Links
Gene Variant Raises Risk of Uterine Fibroids
Date:2/24/2009

Mutation discovered more common in white women, but different genes might raise risk in black women

TUESDAY, Feb. 24 (HealthDay News) -- Researchers have found a genetic marker that may indicate if a woman has a greater chance of developing uterine fibroids, a new study says.

Shorter, white women who test positive for the TC227 allele in their HMGA2 gene may be more likely to develop the muscular tumors in their uterus, according to a study of 248 pairs of sisters and their relatives. HMGA2 is linked to a person's height and the TC227 allele may be part of the gene.

"This genetic indicator could prove, after further investigations, to be valuable information for women making decisions about medical management of fibroids," senior study author Cynthia Morton, a director of cytogenetics at Brigham and Women's Hospital. "A woman with symptomatic fibroids might one day undergo diagnostic testing for the TC227 allele to determine whether she's genetically predisposed to develop additional fibroids."

The research appears online in Human Genetics.

Only white women were studied because the TC227 allele is much less common in black women.

"We believe that there are multiple genetic indicators for fibroids, in addition to the TC227 allele in white women, including genetic risk alleles for predisposition specific in black women who suffer an earlier age of onset and more severe fibroid symptoms," Morton said.

More information

The U.S. Department of Health and Human Services has more about uterine fibroids.



-- Kevin McKeever



SOURCE: Brigham and Women's Hospital, news release, February 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1

Related medicine news :

1. Gene Variant Tied to Severity of Drinking
2. Gene Variant Raises Risk for Brain Cancer at Young Age
3. Gene Variant May Hike Womens Risk of Alzheimers
4. Biologist finds plant polymerases IV and V are really variants of Polymerase II
5. Gene Variant Tied to Smokers Risk of Lung Cancer
6. Genetic Variants Tied to Obesity
7. NEW Line of Pushbutton Pill Cases Launched by Variant Products
8. Newly found gene variants account for kidney diseases among African-Americans
9. Genetic variants associated with vitamin B12
10. APA resolves to play leading role in improving treatment for gender-variant people
11. Gene Variant May Contribute to Alzheimers Disease
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Gene Variant Raises Risk of Uterine Fibroids
(Date:5/26/2017)... ... May 26, 2017 , ... Water damage to the flooring of several ... had left education officials with a number of critical issues to address before students ... to be accomplished with little or no disruption to class schedules. Second, the project ...
(Date:5/24/2017)... ... May 24, 2017 , ... In modern research, success depends ... instruments for research and understanding the basic principles that were designed to drive ... innovations in stereo microscopy for brightfield and fluorescence typically used in laboratories working ...
(Date:5/24/2017)... ... 24, 2017 , ... Altec Products, Inc., a leader in enterprise ... one-day technology conference in San Diego, CA. , At nVerge 2017, Altec will ... utilize and enhance their Sage ERP solutions by providing improved visibility and control to ...
(Date:5/24/2017)... ... May 24, 2017 , ... Drs. ... NY, who have now spent 10 years as clinical instructors for the reputable ... College of Dentistry. Through the program, private practitioners receive cutting-edge clinical training and ...
(Date:5/24/2017)... ... , ... Patients who want to receive cosmetic dentistry procedures such as Invisalign® ... for a consultation, with or without a referral. Dr. Bedich enjoys improving the appearance ... , Dr. Bedich offers a variety of cosmetic dentistry services at his practice that ...
Breaking Medicine News(10 mins):
(Date:5/10/2017)... MARLBOROUGH, Mass., May 10, 2017 Hologic, Inc. ... financial results for the fiscal second quarter ended April ... (EPS) of $1.84 increased 666.7% compared to the prior ... business resulted in a significant gain, while non-GAAP diluted ... increased 3.2%, or 3.8% in constant currency terms.  Excluding ...
(Date:5/10/2017)... Md. , May 10, 2017 CSSi, ... solutions for the clinical research industry, is proud to ... www.CSSiEnroll.com . The new website features both enriched content ... user experience and enhances the company,s already well-established position ... industry. "After many months of hard ...
(Date:5/9/2017)... 9, 2017  Semler Scientific, Inc. (OTCQB: SMLR), ... to improve the clinical effectiveness and efficiency of ... first quarter ended March 31, 2017. ... customers to identify when preventive care options are ... like heart attacks or strokes occur," said ...
Breaking Medicine Technology: