Navigation Links
Gene Variant May Help Some Overcome Adversity
Date:3/7/2010

It appears to disconnect the link between stress and death risk, researchers say

SUNDAY, March 7 (HealthDay News) -- The study of a link between misery and death has helped researchers identify a gene variant fostering resilience in the face of adversity.

The U.S. research team focused on a gene called IL6, which is known to cause inflammation in the body and contributes to cardiovascular disease, neurodegeneration and some types of cancer.

"The IL6 gene controls immune responses but can also serve as 'fertilizer' for cardiovascular disease and certain kinds of cancer," study author Steven Cole, an associate professor of medicine in the division of hematology-oncology at the University of California, Los Angeles and a member of the UCLA Cousins Center for Psychoneuroimmunology, said in a university news release.

"Our studies were able to trace a biochemical pathway through which adverse life circumstances -- fight-or-flight stress responses -- can activate the IL6 gene,' he explained. "We also identified the specific genetic sequence in this gene that serves as a target of that signaling pathway, and we discovered that a well-known variation in that sequence can block that path and disconnect IL6 responses from the effects of stress."

Cole and colleagues also found that people with the most common type of IL6 gene had an increased risk of death for about 11 years after they'd experienced a stressful life event significant enough to trigger depression. But this increased risk of death didn't occur in people with a less common variant of the gene.

The research was released online in advance of publication in an upcoming print issue of the journal Proceedings of the National Academy of Sciences.

In their examination of IL6, Cole and colleagues used a combination of computer modeling, test-tube biochemistry, stress studies in animals, and human genetic epidemiology. This approach
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved

Page: 1 2

Related medicine news :

1. Scientists demonstate link between genetic variant and effectiveness of smoking cessation meds
2. Scientists discover genetic variant associated with prostate cancer in African Americans
3. Gene Variant Doubles Risk of Prostate Cancer in Black Men
4. Gene Variant Tied to More Aggressive Prostate Cancer
5. Gene variant linked to moderated symptoms of beta-thalassemia
6. Gene variant predicts medication response in patients with alcohol dependence
7. Gene Variants Can Predict Threat of Heart Disease
8. Gene Variants Linked to Lung Cancer Identified
9. Gene Variant Protects Black Heart Failure Patients
10. Gene Variant Boosts Risk for Stress-Related Ischemia
11. Gene Variant Boosts Risk of Severe Diabetic Eye, Kidney Diseases
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2014)... 2014 Every year, cataracts affect over 22 ... the leading cause of blindness in the world. Characterized by ... the iris, cataracts are estimated to affect an additional 30 ... aging population. Cataracts are just one of the many conditions ... Tracy of Carlsbad Eye Care screens patients for a number ...
(Date:8/28/2014)... August 28, 2014 Atlantic Information Services, ... the latest addition to its Management Insight Series, ... Major Patient Privacy/Security Risk . The new report is ... the risks associated with portable electronic devices, and assure ... requirements. , With expert advice on how to conduct ...
(Date:8/28/2014)... Francisco, CA (PRWEB) August 28, 2014 ... by small and mid-sized healthcare organizations, today announced that ... the online appointment company ZocDoc , to head ... the company has created a sales management position. , ... a startup like DoctorBase that already has so much ...
(Date:8/28/2014)... (PRWEB) August 28, 2014 Top ... many web hosting companies and announces Bluehost, HostMonster ... recommended suppliers for the webmasters worldwide who want ... rates. , As the world’s most popular server-side ... and many other general-purpose programs. It is now ...
(Date:8/28/2014)... (PRWEB) August 28, 2014 MarijuanaDoctors.com is ... physician, James Patel M.D. of Livermore, California. As always, ... and most qualified physicians, and in accordance with that, ... patients to Dr. Patel’s practice. , Initially finding his ... young age, Dr. Patel was shaped by his mother’s ...
Breaking Medicine News(10 mins):Health News:Cataract Awareness Month an Opportunity to Focus on Vision Care and Ocular Health 2Health News:New Report Offers Best Practices for Avoiding the Patient Privacy/Security Risks Posed by Mobile Devices 2Health News:DoctorBase Hires Josh Angeles as Vice-President of Sales 2Health News:Army Colonel Dr. James Patel Joins the Medical Marijuana Industry 2Health News:Army Colonel Dr. James Patel Joins the Medical Marijuana Industry 3Health News:Army Colonel Dr. James Patel Joins the Medical Marijuana Industry 4
... Reporter , MONDAY, Dec. 12 (HealthDay News) -- Children of ... birth defects, finds a new study that should allay some ... DNA damage done by chemotherapy and radiation of the reproductive ... damaged genes, researchers say. "We found that DNA damage ...
... 2011) Dr. Rabab Mohsin, an internal medicine resident ... Bailey of the University of Kentucky Gill Heart Institute, ... a large study group of women. Working ... Bailey and fellow investigators identified women who reported arrhythmia ...
... It has been well established that certain lifestyle habits relate ... cancer). In a well-done analysis, the authors estimate the ... of lifestyle and environmental factors. They find that smoking ... cancer, with 19.4% of cancer cases in the UK attributable ...
... NY, December 13, 2011JDRF-funded researchers have begun enrolling adult ... to test whether metformina drug commonly used to treat type ... complications in people with T1D. The REMOVAL study (Reducing ... international trial that will study 500 patients with T1D aged ...
... a bed has to deal with numerous complications. Frequently, ... call them. Bony prominences, such as the sacrum, coccyx ... lead to tissue necrosis. Damage can extend into the ... ulcers are entryways for germs, which can trigger sepsis. ...
... ride into the retina on nanoparticles called dendrimers offers ... retinitis pigmentosa. A collaborative research study among investigators at ... Medicine shows that steroids attached to the dendrimers targeted ... of the eye unaffected and preserving vision. The ...
Cached Medicine News:Health News:Birth Defects Seem Rare in Kids of Childhood Cancer Survivors 2Health News:Birth Defects Seem Rare in Kids of Childhood Cancer Survivors 3Health News:JDRF-funded study seeks to reduce cardiovascular risk 2Health News:Lying and sitting more comfortably 2Health News:Nanoparticles help researchers deliver steroids to retina 2
(Date:8/27/2014)... /PRNewswire-iReach/ -- In a new, interactive guide, DICOM ... the electronic medical record (EMR) and image management ... first-hand, how seamless integration makes diagnostic studies accessible ... http://photos.prnewswire.com/prnh/20140827/140443 "Just five ... within the patient record was near impossible. Fast-forward ...
(Date:8/27/2014)... , Aug. 27, 2014 Varian Medical Systems (NYSE: ... current Salt Lake City manufacturing facility ... of Utah to ultimately create 1,000 ... 20 years. " Utah ... talent, many of whom can be credited with Varian,s success ...
(Date:8/27/2014)... By now, if you haven,t heard about the ... planet. The awareness campaign has brought this devastating disease to ... over $88.5 Million (and counting) for ALS. Every day, more ... starting to as well. One such company, Acorn ... who actually works with ALS sufferers and helps to provide ...
Breaking Medicine Technology:DICOM Grid Launches Interactive Guide to Demonstrate Image-Enabling the EMR 2Varian Medical Systems Groundbreaking on Facility Expansion Triggers Influx of New Jobs to Salt Lake 2Varian Medical Systems Groundbreaking on Facility Expansion Triggers Influx of New Jobs to Salt Lake 3Varian Medical Systems Groundbreaking on Facility Expansion Triggers Influx of New Jobs to Salt Lake 4Acorn Stairlifts Gives a Lift to the ALS Ice Bucket Challenge 2
...  Today, Asubio announced the initiation of a landmark ... medication being developed to improve neurological function in ... In accordance with its internal focus ... development activities at a peer-attended symposium at the ...
... Schein, Inc. (NASDAQ: HSIC ), the world,s ... dental, medical and animal health office-based practitioners, celebrated Earth ... program which helps healthcare practitioners more easily use environmentally-friendly ... protecting the health of our planet is an important ...
Cached Medicine Technology:Asubio Initiates Landmark Clinical Study in Spinal Cord Injury 2Asubio Initiates Landmark Clinical Study in Spinal Cord Injury 3Henry Schein Celebrates Earth Day 2Henry Schein Celebrates Earth Day 3
The perfect quick consult for the busy cardiologist, The Ultimate Echo Guide puts the most clinically essential information in an easy access format....
... a quick-lookup reference for ECG interpretation ... presents the basics (anatomy and physiology ... system of the heart, basic ECG ... algorithms, emergency medications, and comprehensive information ...
Dx/Rx: Heart Failure has tables and figures that summarize important clinical data and current professional society recommendations and up-to-date information for diagnosis and treatment of Heart Fai...
Topics include: ECG reading, ACLS (all the latest protocols and pearls), CHF, acute MI, cardiac testing, palpitations, pericarditis, arrhythmias, murmurs, athletes, valvular disease, endocarditis, sy...
Medicine Products: