Navigation Links
Gene Variant May Help Some Overcome Adversity
Date:3/7/2010

It appears to disconnect the link between stress and death risk, researchers say

SUNDAY, March 7 (HealthDay News) -- The study of a link between misery and death has helped researchers identify a gene variant fostering resilience in the face of adversity.

The U.S. research team focused on a gene called IL6, which is known to cause inflammation in the body and contributes to cardiovascular disease, neurodegeneration and some types of cancer.

"The IL6 gene controls immune responses but can also serve as 'fertilizer' for cardiovascular disease and certain kinds of cancer," study author Steven Cole, an associate professor of medicine in the division of hematology-oncology at the University of California, Los Angeles and a member of the UCLA Cousins Center for Psychoneuroimmunology, said in a university news release.

"Our studies were able to trace a biochemical pathway through which adverse life circumstances -- fight-or-flight stress responses -- can activate the IL6 gene,' he explained. "We also identified the specific genetic sequence in this gene that serves as a target of that signaling pathway, and we discovered that a well-known variation in that sequence can block that path and disconnect IL6 responses from the effects of stress."

Cole and colleagues also found that people with the most common type of IL6 gene had an increased risk of death for about 11 years after they'd experienced a stressful life event significant enough to trigger depression. But this increased risk of death didn't occur in people with a less common variant of the gene.

The research was released online in advance of publication in an upcoming print issue of the journal Proceedings of the National Academy of Sciences.

In their examination of IL6, Cole and colleagues used a combination of computer modeling, test-tube biochemistry, stress studies in animals, and human genetic epidemiology. This approach
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved

Page: 1 2

Related medicine news :

1. Scientists demonstate link between genetic variant and effectiveness of smoking cessation meds
2. Scientists discover genetic variant associated with prostate cancer in African Americans
3. Gene Variant Doubles Risk of Prostate Cancer in Black Men
4. Gene Variant Tied to More Aggressive Prostate Cancer
5. Gene variant linked to moderated symptoms of beta-thalassemia
6. Gene variant predicts medication response in patients with alcohol dependence
7. Gene Variants Can Predict Threat of Heart Disease
8. Gene Variants Linked to Lung Cancer Identified
9. Gene Variant Protects Black Heart Failure Patients
10. Gene Variant Boosts Risk for Stress-Related Ischemia
11. Gene Variant Boosts Risk of Severe Diabetic Eye, Kidney Diseases
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/12/2014)... 12, 2014 The rise in the ... for new advanced network architectures to suit the upsurge. ... industry with increasing cloud storage technologies. The data traffic ... more mobility devices. This has resulted in larger and ... driving forces for the SDN market. , The North ...
(Date:7/12/2014)... Dennis Thompson HealthDay Reporter ... way to guarantee that a surgical technique used to grind ... increase the risk of spreading cancer to other parts of ... advisory panel to the Food and Drug Administration also said ... power morcellation -- should sign a written consent stating that ...
(Date:7/12/2014)... Dallas, TX (PRWEB) July 12, 2014 ... training market research report, ‘cognitive assessment and ... able to monitor, assess, train, or enhance ... several uses such as in dementia screening, ... concussion management, classroom learning, self assessment, brain ...
(Date:7/12/2014)... The Security Analytics market is estimated ... million by 2019, at an expected CAGR of 9.7% ... to counter the increasing number of security breaches, continued ... defense systems in organizations are enormous. Vendors in the ... existing architecture to develop better and more secure systems. ...
(Date:7/12/2014)... (PRWEB) July 12, 2014 Tylenol ... continue to move forward in the federal multidistrict ... of Pennsylvania, Bernstein Liebhard LLP reports. According to ... Judge Lawrence F. Stengel has ordered the deposition ... Judge Stengel found that the witness’s testimony concerning ...
Breaking Medicine News(10 mins):Health News:North America Software Defined Network (SDN) Market Worth $1,443.8 Million by 2019 - New Report by MicroMarket Monitor 2Health News:North America Software Defined Network (SDN) Market Worth $1,443.8 Million by 2019 - New Report by MicroMarket Monitor 3Health News:North America Software Defined Network (SDN) Market Worth $1,443.8 Million by 2019 - New Report by MicroMarket Monitor 4Health News:North America Software Defined Network (SDN) Market Worth $1,443.8 Million by 2019 - New Report by MicroMarket Monitor 5Health News:FDA Advisers Weigh Risks of Procedure for Removal of Uterine Fibroids 2Health News:FDA Advisers Weigh Risks of Procedure for Removal of Uterine Fibroids 3Health News:Global Cognitive Assessment & Training Market: 27.3% CAGR to 2018 Says a New Research Report Available at LifeScienceIndustryResearch.com 2Health News:Global Cognitive Assessment & Training Market: 27.3% CAGR to 2018 Says a New Research Report Available at LifeScienceIndustryResearch.com 3Health News:Global Cognitive Assessment & Training Market: 27.3% CAGR to 2018 Says a New Research Report Available at LifeScienceIndustryResearch.com 4Health News:Global Cognitive Assessment & Training Market: 27.3% CAGR to 2018 Says a New Research Report Available at LifeScienceIndustryResearch.com 5Health News:North America Security Analytics Market Worth $1,215.2 Million by 2019 - New Report by MicroMarket Monitor 2Health News:North America Security Analytics Market Worth $1,215.2 Million by 2019 - New Report by MicroMarket Monitor 3Health News:North America Security Analytics Market Worth $1,215.2 Million by 2019 - New Report by MicroMarket Monitor 4Health News:Tylenol Lawsuit News: U.S. District Judge Overseeing Federal Tylenol Liver Damage Litigation Orders Deposition of Former McNeil President, Bernstein Liebhard LLP Reports 2Health News:Tylenol Lawsuit News: U.S. District Judge Overseeing Federal Tylenol Liver Damage Litigation Orders Deposition of Former McNeil President, Bernstein Liebhard LLP Reports 3Health News:Tylenol Lawsuit News: U.S. District Judge Overseeing Federal Tylenol Liver Damage Litigation Orders Deposition of Former McNeil President, Bernstein Liebhard LLP Reports 4
... , Anyone confined to a wheelchair or a bed ... from bedsores or decubitus ulcers as physicians call them. ... are especially endangered spots. Unrelieved pressure can lead to ... at the worst, into bones themselves. The ulcers are ...
... , TUESDAY, Dec. 13 (HealthDay News) -- Undiagnosed chronic fatigue ... who are absent from school for extended periods of time ... that would explain why they,re out of school, a new ... 2,855 students aged 11 to 16 at three secondary schools ...
... infrastructure, inefficient distribution channels and disruptive black markets must ... with the growing problem of malaria, according to a ... Systems and Management . Historically, malaria is humanity,s ... some regions it remains the biggest infectious threat in ...
... By Kathleen Doheny HealthDay Reporter , MONDAY, ... to ease lower back pain frequently undergo an MRI beforehand. ... have little or no clinical value for these patients. ... the MRI does not typically improve results for patients who ...
... player died from complications due to sickle cell trait (SCT) ... all Division I student-athletes. A new study evaluated the ... help identify more than 2,000 athletes with SCT, but warns ... policy is well-intentioned, screening is just the first step," says ...
... By Steven Reinberg HealthDay Reporter , MONDAY, Dec. ... for attention deficit-hyperactivity disorder (ADHD) do not seem to face ... There have been fears that these drugs can cause ... observational study found no evidence that these effects posed a ...
Cached Medicine News:Health News:Lying and sitting more comfortably 2Health News:Chronic Fatigue Tied to Extended School Absences 2Health News:A logistics approach to malaria in Africa 2Health News:Study Questions Use of MRI Before Back-Pain Injections 2Health News:Study Questions Use of MRI Before Back-Pain Injections 3Health News:NCAA mandatory sickle cell screening program not enough to save athletes' lives 2Health News:ADHD Drugs Don't Raise Risk of Heart Problems: Study 2Health News:ADHD Drugs Don't Raise Risk of Heart Problems: Study 3
(Date:7/11/2014)... HILL, N.C. , July 11, 2014 /PRNewswire/ ... of pharmaceutical marketing and, consequently, organizations are turning ... for patients. As part of this ... it,s important to educate, communicate and engage patients ... disease awareness to patient empowerment. By mapping the ...
(Date:7/11/2014)... July 11, 2014  Rock Creek Pharmaceuticals, Inc. (NASDAQ: ... announced that the Food and Drug Administration ("FDA"), has ... on RCP,s Investigational New Drug ("IND") application before granting ... the US. Dr. Chris Chapman , ... comments on our IND. When we receive the agency,s ...
(Date:7/11/2014)... 11, 2014 According to ... Composition of Material, Application (Healthcare, Homeland security, Industrial ... (Personal Instrument, Hand-Held Instruments, Fixed, and Installed Instruments) ... 2013 - 2020", published by MarketsandMarkets, the Scintillator Market is ... from 2014 to 2020, and reach $479.16 Million ...
Breaking Medicine Technology:New Study Uses Six-Step Patient Journey as Framework for Consumer-Focused Marketing Opportunities 2Rock Creek Pharmaceuticals Issues Update On US Investigational New Drug Application 2Scintillator Market will be worth $479.16 Million by 2020 2Scintillator Market will be worth $479.16 Million by 2020 3Scintillator Market will be worth $479.16 Million by 2020 4
... The Fourth Annual Medical Product Outsourcing (MPO) Symposium ... medical device strategist and entrepreneur Julia S. Rasor, founder ... critical to device manufacturing efficiency by providing real-world examples ... "Many organizations flounder as different functional groups do their ...
... FAIRFAX, Va., Oct. 12 General Dynamics Information Technology, ... GD ), has been awarded a contract to support ... modernization of current Army medical facilities and transition to ... contract, one of five awarded by the U.S. Army ...
Cached Medicine Technology:MPO Symposium Keynote to Address Organizational Strategies for Medical Device Manufacturers 2General Dynamics Awarded Contract to Outfit and Transition U.S. Army Medical Facilities 2General Dynamics Awarded Contract to Outfit and Transition U.S. Army Medical Facilities 3
Greenberg micro instrument holder is a flexbar arm used to hold micro instruments used repeatedly within retracted fields. Holds instruments with shafts up to 1/8 in diameter....
Length-9 (229 mm) Tapered retractor blades. 1/16 x 1/4 (1.6 mm x 19 mm)....
Kit is supplied with four secondary bars. Secondary bars attach to primary bar. Length 12 (305 mm)....
Pattie Tray...
Medicine Products: