Navigation Links
Gene Variant Could Lower Alzheimer's Risk
Date:1/12/2010

oes the gene variant work its magic? Lipton put forth two theories.

"We know that it protects against disease in blood vessels," he said. "It lowers the risk of heart attack and stroke, and stroke is a risk factor for cognitive decline. So it protects the brain against atherosclerotic disease.

"The other mechanism is more speculative. It might protect against formation of proteins involved in Alzheimer's disease, such as beta-amyloid," Lipton said. The buildup of beta-amyloid protein plaques within brain tissue has long been a hallmark of Alzheimer's disease.

One expert found the study results intriguing.

"It's a great candidate gene for research on Alzheimer's disease and dementia," said Dr. James Burke, director of the Memory Disorders Clinic at Duke University Medical Center in Durham, N.C.

The benefit probably does not come from improved blood flow to the brain, he said. "I think it's related to lipid-cholesterol transport and metabolism," Burke said. Drugs that raise HDL level in the same way as the variant gene might therefore be useful against Alzheimer's disease, he reasoned.

According to the researchers, the CETP gene variant was first identified in a population of Ashkenazi Jews, descendents of western and central Europeans. The current study was done among an ethnically diverse population of people living in the Bronx who have been followed for 25 years.

It remains a small study that requires verification in broader research, Lipton said. "We have enrolled 600 additional people who we are following and we hope to enroll other groups," he noted.

Most studies of the genetics of Alzheimer's disease have concentrated on genes associated with increased risk, such as the ApoE-a4 gene, which also is involved in cholesterol metabolism, Lipton pointed out. "We hope that by understanding the genetics of the condition we can improve diagnosis or treatment or both," he said.


'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved

Page: 1 2 3

Related medicine news :

1. Genetic variant associated with aggressive form of prostate cancer
2. Gene Variant Seems to Guard Against Asthma, COPD
3. Five Gene Variants May Be Linked to Lung Disease
4. Genetic Variant Slows AIDS Progression
5. Gene Variants Behind Vulnerability to Yeast Infections
6. Clues to visual variant Alzheimers; myopia and diabetic retinopathy risk
7. Glaucoma Tied to Gene Variants in Blacks
8. Trio of Gene Variants Discovered That May Raise Alzheimers Risk
9. Variants of umami taste receptor contribute to our individualized flavor worlds
10. International Collaboration led by Dr. Pablo V. Gejman,Researcher At NorthShore University HealthSystem's Research Institute, Finds Genetic Association of Schizophrenia to Chromosome 6p Variant
11. Worlds largest DNA scan for autism uncovers new gene variant for disorder
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/12/2014)... 12, 2014 The rise in the ... for new advanced network architectures to suit the upsurge. ... industry with increasing cloud storage technologies. The data traffic ... more mobility devices. This has resulted in larger and ... driving forces for the SDN market. , The North ...
(Date:7/12/2014)... The "North American Interventional ... by Angioplasty Balloon (Plain/Old, Cutting), Stent ... Filter (Retrievable), Endovascular Stent Graft - ... the major market drivers, restraints, and ... , Browse 108 market data tables ...
(Date:7/12/2014)... (PRWEB) July 12, 2014 The Security ... in 2013 to $3,376.6 million by 2019, at an ... and 2019. The challenges to counter the increasing number ... existence of outdated cyber defense systems in organizations are ... innovating and remodeling their existing architecture to develop better ...
(Date:7/12/2014)... July 12, 2014 Casinos ... despite rising competition from international and online casinos. Revenue ... over the five years through 2014-15. Greater per capita ... more gaming services. Rises in discretionary income levels have ... money on non-essential items such as casino gambling services. ...
(Date:7/12/2014)... "The second toes cross over the big toes ... shoes," said an inventor from East Hartford, Conn. This gave ... happening. , He then created a prototype of the Comfort ... and big toes from overlapping. This avoids discomfort and pain, ... easy to use, it's ideal for people with foot problems, ...
Breaking Medicine News(10 mins):Health News:North America Software Defined Network (SDN) Market Worth $1,443.8 Million by 2019 - New Report by MicroMarket Monitor 2Health News:North America Software Defined Network (SDN) Market Worth $1,443.8 Million by 2019 - New Report by MicroMarket Monitor 3Health News:North America Software Defined Network (SDN) Market Worth $1,443.8 Million by 2019 - New Report by MicroMarket Monitor 4Health News:North America Software Defined Network (SDN) Market Worth $1,443.8 Million by 2019 - New Report by MicroMarket Monitor 5Health News:North American Interventional Cardiology & Peripheral Vascular Devices Market - New Report by MarketsandMarkets 2Health News:North American Interventional Cardiology & Peripheral Vascular Devices Market - New Report by MarketsandMarkets 3Health News:North American Interventional Cardiology & Peripheral Vascular Devices Market - New Report by MarketsandMarkets 4Health News:North American Interventional Cardiology & Peripheral Vascular Devices Market - New Report by MarketsandMarkets 5Health News:North America Security Analytics Market Worth $1,215.2 Million by 2019 - New Report by MicroMarket Monitor 2Health News:North America Security Analytics Market Worth $1,215.2 Million by 2019 - New Report by MicroMarket Monitor 3Health News:North America Security Analytics Market Worth $1,215.2 Million by 2019 - New Report by MicroMarket Monitor 4Health News:Casinos in Australia Industry Market Research Report Now Updated by IBISWorld 2Health News:Casinos in Australia Industry Market Research Report Now Updated by IBISWorld 3Health News:Casinos in Australia Industry Market Research Report Now Updated by IBISWorld 4
... WASHINGTON, Oct. 9 The leaders of Ford Motor Company ... to help revitalize America,s auto industry - they,re also coming ... million to give babies a healthy start in life. ... Library of Congress, the March of Dimes honored special volunteers ...
... With Healthcare Reform ... Certified Professional Coders to meet the upcoming need in healthcare reimbursements and coding. , ... Leesburg, Virginia (Vocus) October 9, 2009 ... is pleased to announce that two of its associates, Jackie Penna, CPC, and Nikki Hendrix, ...
... NCQA ... , ... (Vocus) October 9, 2009 -- Kaiser Permanente Hawaii leads the nation in ... for 2009. The data provided by the private, non-profit organization dedicated to improving health ...
... , ... a Physical Therapist has received a home exercise program, or HEP, that consisted of 2 to ... exercise. FIZIO is a new online service that is set on changing this practice by giving ... , ...
... ... an innovative iPhone application. The application allows for voice, alarm and text messages to be ... by Nurses who are finding they have more time to spend caring for patients. ... Sarasota,Fla (PRWEB) October 9, ...
... , ... Chews-4-Health, the world’s first super fruit, sea ... television show “Beauty Spaces” (from the producers of the award-winning show ... on the WE (Woman’s Entertainment) Network on Oct. 16 at 7:30 ...
Cached Medicine News:Health News:Ford and Labor Leaders Join Forces with March of Dimes 2Health News:Capture Billing Associates Elected to Local Chapter of the American Academy of Professional Coders 2Health News:Kaiser Permanente Hawaii Leads the Nation in Breast Cancer Screening 2Health News:Kaiser Permanente Hawaii Leads the Nation in Breast Cancer Screening 3Health News:New Online Service Uses Video Instruction to Simplify Physical Therapy Exercises 2Health News:New Online Service Uses Video Instruction to Simplify Physical Therapy Exercises 3Health News:New Online Service Uses Video Instruction to Simplify Physical Therapy Exercises 4Health News:Sarasota Memorial Hospital Uses New Technology to Enhance Patient Experience 2Health News:Sarasota Memorial Hospital Uses New Technology to Enhance Patient Experience 3Health News:Chews-4-Health Dietary Supplements to be Featured on 'Beauty Spaces' 2Health News:Chews-4-Health Dietary Supplements to be Featured on 'Beauty Spaces' 3
(Date:7/11/2014)... On Thursday, July 10, ... Dow Jones Industrial Average finished the day 0.42% lower at ... The losses were broad based as eight out of ten ... Care Sector Index ended the day at 711.88, down 0.02%, ... month. Investor-Edge has initiated coverage on the following equities: Covidien ...
(Date:7/11/2014)... , July 11, 2014 Research ... addition of the "Immunoprotein Diagnostic Testing Market ... the highest CAGR of 6% and is expected ... report to their offering. ... immunoprotein diagnostic testing has been segmented according to ...
(Date:7/11/2014)... Show organisers report ... Expo 2014 were a brand new audience ... London , plus a 10% increase ...      (Logo: http://photos.prnewswire.com/prnh/20130723/629764-a) ...      (Photo: http://photos.prnewswire.com/prnh/20140711/696892-b ) ...
Breaking Medicine Technology:Health Care Equipment Equities Movers and Shakers -- Research on Covidien, Baxter, DexCom, and Boston Scientific 2Health Care Equipment Equities Movers and Shakers -- Research on Covidien, Baxter, DexCom, and Boston Scientific 3Health Care Equipment Equities Movers and Shakers -- Research on Covidien, Baxter, DexCom, and Boston Scientific 4Immunoprotein Diagnostic Testing Market - Forecasts to 2019: Expected to grow at the highest CAGR of 6% and is expected to be valued at USD 4,943.0 million 2UK's Flagship Health & Safety Event Has Successful Inaugural Year in London 2UK's Flagship Health & Safety Event Has Successful Inaugural Year in London 3UK's Flagship Health & Safety Event Has Successful Inaugural Year in London 4
... DUBLIN, Calif., April 14, 2011 Carl Zeiss ... microscope system at the 79th Annual Meeting of ... Denver, Colo. Based on the breakthrough OPMI® Pentero ... offers innovative new features and customer benefits such ...
... results from the largest multicenter clinical trial for heart ... International Society for Heart & Lung Transplantation (ISHLT) 31st ... show clinical benefit for the use of Everolimus in ... randomized patients at 67 medical centers spanning 5 continents. ...
Cached Medicine Technology:PENTERO 900: Elevating Excellence in Microsurgery to a New Level 2PENTERO 900: Elevating Excellence in Microsurgery to a New Level 3Results From Largest Study of Anti-Rejection Therapy for Heart Transplant Patients Will be Released at ISHLT Meeting 2Results From Largest Study of Anti-Rejection Therapy for Heart Transplant Patients Will be Released at ISHLT Meeting 3Results From Largest Study of Anti-Rejection Therapy for Heart Transplant Patients Will be Released at ISHLT Meeting 4
Introducer Sheath Designed for Vascular Access...
Used to introduce balloon, electrode, closed or non-tapered end and,other catheters....
... The Driver Stent design, ... surpasses the limitations of stainless ... makes possible thinner struts, for ... support. The Driver Coronary Stent ...
The TAXUS Express Paclitaxel-Eluting Coronary Stent System is indicated for improving luminal diameter for the treatment of de novo lesions = 28 mm in length in native coronary arteries = 2.5 to = 3....
Medicine Products: