Navigation Links
Gene Ups Risk for Those on Blood-Thinner Plavix
Date:12/22/2008

Younger patients with the mutation faced higher odds of heart attack, death, study found

MONDAY, Dec. 22 (HealthDay News) -- A gene variation can make younger heart attack patients more prone to another heart attack, death or other heart problems if they receive the anti-clotting drug Plavix, researchers report.

The study is published in the Dec. 23 online edition of The Lancet.

Plavix plus low-dose aspirin are often used to prevent blood vessels from clogging after a heart attack or after patients receive an artery-opening stent.

But some patients do not do well on Plavix (clopidogrel). Until now, the reasons for that variance have been unclear.

Plavix "targets a very important receptor on platelets, but people vary substantially in how good an anti-clotting effect they have" from the drug, explained Dr. Robert F. Storey, from the Cardiovascular Research Unit at the University of Sheffield School of Medicine in the United Kingdom. He is also the author of an accompanying comment in the journal.

"The variation in response is partly due to genetics, but there are other factors such as age which influence the response," Storey said.

For the study, a team led by Dr. Gilles Montalescot, from the Hopital Pitie-Salpetriere in Paris, collected data on 259 patients aged 45 and younger who suffered a first heart attack and were given Plavix.

Among these patients, 28 percent carried a gene variation called CYP2C19*2. This variation is common among the western population and even more common in Asia, the researchers noted.

During an average of a year of follow-up, patients with the gene variation were more than three-and-a-half times more likely to die, have another heart attack or require additional cardiac treatment compared to those without the variation, the researchers found.

In addition, patients with CYP2C19*2 were six times more likely to have a b
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. Patients with Medicaid and those lacking insurance have higher risk of advanced laryngeal cancer
2. AASM encourages those student-athletes at risk for developing osa to visit a sleep clinic
3. Overweight toddlers and those not in day care at risk for iron deficiency
4. Promising drug combination may help those with ocular melanoma that has spread
5. New study examines brain-gut relationship in those suffering with stomach pain or discomfort
6. Quality Innovators to Network in Atlanta Sept. 19-21: Learn from Those Who Got It Right
7. State Director of Health Commends Ohio Dentists and ODH Bureau of Oral Health for Serving Those in Need
8. Cleveland Clinic and The Larry King Cardiac Foundation Partner to Provide Heart Surgery to Those in Need
9. World Institute on Disability and American Red Cross Partner to Provide Innovative Training to Better Assist Those With Disabilities
10. Those With Disabilities as Well as Aging Population Throughout Country Now Have Access to Thousands of Specialized Products
11. Holiday Gifts for Those With Disabilities & Other Special Needs
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Gene Ups Risk for Those on Blood-Thinner Plavix
(Date:5/29/2015)... May 29, 2015 The third annual ... event, now closed to new registration, starts outside the ... This exciting competitive running event demonstrates the power of ... a public benefit – in this case, historic preservation. ... around the famed Ocean Drive and passes by many ...
(Date:5/29/2015)... (PRWEB) May 29, 2015 Dot Hill can mark ... 91-year-old resident of Lake Prince Woods retirement community is ... in Virginia Beach, Virginia. , “It was great fun!”, she exclaimed. ... children didn’t want me to so they thought this would be ... stepped into a vertical wind tunnel,” she described. “I don’t ...
(Date:5/29/2015)... (PRWEB) May 29, 2015 To compile ... research, choosing systems that have several awards for clinical ... on what systems stood out to them in terms ... inclusion as well. , The 50 Great Health Systems ... Adventist Health System (Altamonte Springs, Fla.) , Advocate Health ...
(Date:5/29/2015)... FL (PRWEB) May 29, 2015 ... Utah, recently partnered with Stratus Video ... which will facilitate better communication and timely ... (LEP) and hearing loss. Stratus’ video remote ... in-house translators, enabling staff to quickly access ...
(Date:5/29/2015)... New York, NY (PRWEB) May 29, 2015 ... mental wellness, as well as a number of specific ... integrative care, stigma reduction and mental health in the ... speak about mental health. The campaign also brings special ... inspiring those individuals to speak up and seek help ...
Breaking Medicine News(10 mins):Health News:The Newport 10 Miler at Fort Adams, an Outstanding Example of Event Marketing Helping in Preservation, is Now Completely Booked for 2015 2Health News:The Newport 10 Miler at Fort Adams, an Outstanding Example of Event Marketing Helping in Preservation, is Now Completely Booked for 2015 3Health News:Indoor Skydiving Brings Thrills to Seniors 2Health News:Becker's Hospital Review Names 50 Great Health Systems to Know 2Health News:Becker's Hospital Review Names 50 Great Health Systems to Know 3Health News:Stratus Video Interpreting Partners With Intermountain Healthcare to Provide On-Demand Interpretation Services for Patients With Limited English Proficiency (LEP) 2Health News:Stratus Video Interpreting Partners With Intermountain Healthcare to Provide On-Demand Interpretation Services for Patients With Limited English Proficiency (LEP) 3Health News:Stratus Video Interpreting Partners With Intermountain Healthcare to Provide On-Demand Interpretation Services for Patients With Limited English Proficiency (LEP) 4Health News:Mediaplanet Brings Activism to Those Living with Mental Illness in Bew “Mental Health Awareness” Campaign 2
... American Physical Society commends President Obama,s commitment to doubling ... implementing policies that will enhance science and math education; ... percent of the nation,s gross domestic product to investments ... that the U.S. develops effective solutions to challenges in ...
... Managing sick and concerned workers, navigating quarantine barriers ... impact areas facing epidemic-wary managersNEW YORK, April 28 ... spread and monitoring government advisories should prepare to ... epidemic or worst-case pandemic scenario, says New York ...
... TUESDAY, April 28 (HealthDay News) -- A computerized chest ... rooms with chest pains who have serious heart disease, ... in the study, computed tomography angiography (CTA) was 100 ... acute coronary syndrome, according to a report in the ...
... a ,crack in the facade, of the disorder, , , ... of two common genes can raise the risk for ... highlighting the complex genetic roots of the disorder. , ... region, responsible for complex social behavior and abstract thought, ...
... DURECT Corporation,s (Nasdaq: DRRX ) first quarter 2009 ... the conference call that will be broadcast live over the ... Time (1:30 pm Pacific Time).A live audio webcast of the ... http://www.durect.com and clicking "Investor Relations." ...
... 28 DATATRAK International, Inc. (Nasdaq: DATA ... eClinical solutions for the clinical trials industry, today reported ... become the newest member of the DATATRAK CRO Connect ... of CROs, CPI is able to expand its electronic ...
Cached Medicine News:Health News:APS commends President Obama's commitment to greater investment in science 2Health News:Swine Flu Plans Triggering Difficult Legal Questions, Says Noted Pillsbury Attorney 2Health News:Swine Flu Plans Triggering Difficult Legal Questions, Says Noted Pillsbury Attorney 3Health News:Computerized Scan Detects Heart Disease 2Health News:Computerized Scan Detects Heart Disease 3Health News:Research Highlights Genetic Risk for Autism 2Health News:Research Highlights Genetic Risk for Autism 3Health News:Research Highlights Genetic Risk for Autism 4Health News:German CRO clinicalprojects international GmbH Becomes Newest Member of DATATRAK's CRO Connect Program(TM) 2Health News:German CRO clinicalprojects international GmbH Becomes Newest Member of DATATRAK's CRO Connect Program(TM) 3Health News:German CRO clinicalprojects international GmbH Becomes Newest Member of DATATRAK's CRO Connect Program(TM) 4
(Date:5/29/2015)... -- Fair Rate Funding, a leader in TV mesh lawsuit ... Delaware found Thursday that Boston Scientific,s Pinnacle ... prolapse (POP) and Stress Urinary Incontinence (SUI) in women, ... design flaws from the plaintiff, Deborah Barba . ... Transvaginal mesh, also known as TV mesh or ...
(Date:5/29/2015)... 2015 Research and Markets ( http://www.researchandmarkets.com/research/p37spr/north_america ) ... Open System MRI Market - Growth, Trends And Forecasts ... The key players in the industry are GE ... and Toshiba Medical Systems MRI ... because of its higher sensitivity and use of non-ionizing ...
(Date:5/29/2015)... Research and Markets ( http://www.researchandmarkets.com/research/hgs483/cardiovascular ) ... report "Cardiovascular Drug Delivery - Technologies, Markets ... Drug delivery to the cardiovascular system is different ... anatomy and physiology of the vascular system; it ... the body. Drugs can be introduced into the ...
Breaking Medicine Technology:TV Mesh Lawsuit Funding Firm, Fair Rate Funding, Reports Delaware Woman Awarded $100 Million Against Boston Scientific in Pelvic Mesh Verdict. 2TV Mesh Lawsuit Funding Firm, Fair Rate Funding, Reports Delaware Woman Awarded $100 Million Against Boston Scientific in Pelvic Mesh Verdict. 3North America Open System MRI Market 2014-2019 with GE, Hitachi Medical, Philips Healthcare, Siemens Healthcare and Toshiba Medical Dominating 2Global Cardiovascular Drug Delivery Market 2015 - Technologies, Markets and Companies 2Global Cardiovascular Drug Delivery Market 2015 - Technologies, Markets and Companies 3
... Study -NAPA, Calif., March 13 ... the University of Maryland School of Medicine , was ... condition afflicting over 14 million Americans. Dr. Vinocur addressed ... the Department of Dermatology, University of California, Irvine , ...
... is one of a few institutions in the world ... Aurora St. Luke,s Medical Center is one ... a new skin cancer research study that trains the ... )The Young Tumor-Infiltrating Lymphocyte (Y-TIL) trial is a phase ...
Cached Medicine Technology:WBAL Radio Segment With Dr. Leigh Vinocur Addresses Hope for the Rosacea Sufferer 2New Hope to Beat Cancer 2
Sterile squares of smooth foil for repair of the floor of the orbit and other plastic surgery. Available in large size....
Clear Base Stand Magnifiers are ideal for any visual task that requires high magnification....
Bausch & Lomb magnifiers incorporates precision optics and patented ergonomic designs for increased clarity and comfort during use....
Ultra Thin Sheet. Medpor Sheets are commonly used for orbital floor reconstruction and other craniofacial applications....
Medicine Products: