Navigation Links
Gene-Transfer Proves Safe for Vision Problem
Date:9/12/2008

Volunteers with rare eye disease regained partial sight with experimental therapy

FRIDAY, Sept. 12 (HealthDay News) -- Three people with a rare, incurable form of hereditary blindness regained some sight after receiving experimental gene therapy, a new report says.

The patients, all in their early 20s, have Leber congenital amaurosis type 2 (LCA2), a disease in which photoreceptor cells cannot respond to light, because a gene called RPE65 does not properly produce a protein necessary for healthy vision.

In the study, published online in Human Gene Therapy, researchers at the University of Florida used an adeno-associated virus. an apparently harmless virus that already exists in most people. to deliver RPE65 to a small area of the retina.

The subjects said the vision in their treated eyes was slightly improved in dim lighting conditions.

"The patients report seeing brighter areas and perhaps some images, but basically the message is that this treatment is fully safe," William W. Hauswirth, a professor of ophthalmology and member of the university's Powell Gene Therapy Center, said in a news release issued by the university.

No ill effects, other than routine post-surgical soreness, were reported.

"The study has partially restored vision in three young adults, and it demonstrates that gene therapy can be effective in treating human vision disease," Dr. Paul A. Sieving, director of the National Eye Institute, which supported the experiment, said in the same news release. "Many human diseases are inherited in families and result from mutations in single genes. These genetic conditions are particularly suited to potential treatment by gene therapy. This trial to treat vision loss from the condition of Leber congenital amaurosis is an important demonstration of proof of principle and shows that we are on the right track. We can now invest in further work to refine, and ul
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved

Page: 1 2

Related medicine news :

1. Music Therapy Improves Well-Being of Very Ill Patients
2. Safety study indicates gene therapy for blindness improves vision
3. New study finds that add-on therapy improves depressive symptoms in bipolar disorder
4. FDA approves first drug for Huntingtons disease
5. Light Stretching Improves Range of Joint Motion
6. The California Board of Registered Nursing Approves Affiliations for Nursing Program in Glendale, California
7. Free White Paper: Hospital Tests Patient Lift Technologies; Improves Quality of Care
8. Overcoming inhibitors of cell death improves cancer therapy efficacy
9. New study shows calcium significantly improves childrens bone health
10. Madrid Hospital Improves Employee Safety With Ekahau Wi-Fi RTLS
11. Kaiser Permanente Approves $22 Million in Community Benefit Grants in Second Quarter of 2008
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/16/2014)... 16, 2014 Cloud based mobile ... (HLS) & UStream API’S to serve m3u8 streams on ... for broadcasting live video events with hundreds of thousands ... The App Builder is known for making beautiful and ... BlackBerry and Windows 8 and already over 100,000 apps ...
(Date:9/16/2014)... serve of dairy food may reduce the risk of ... foods have not traditionally formed part of the diet. ... by Emeritus Professor Mark Wahlqvist from Monash University,s Department ... Institute, considered the role increased consumption of dairy foods ... longevity. , "In a dominantly Chinese food culture, ...
(Date:9/16/2014)... other workplace incident, a statistic that transport safety experts ... hosted by QUT,s Centre for Accident Research & Road ... Transport Conference (OSIT) to be held on the Gold ... from all facets of transport safety including roads, rail, ... , CARRS-Q research fellow Darren Wishart said the aim ...
(Date:9/16/2014)... Definitive Healthcare , the leading ... is pleased to announce the release of its ... available for subscription, features detailed hospital profiles that ... , The Canadian database spans Canada’s ten providences ... 750 hospitals. Each hospital profile provides data ...
(Date:9/16/2014)... The Muscular Dystrophy Association is offering assistance ... affected by muscle disease, including muscular dystrophy, amyotrophic ... MDA offers this service annually for adults and ... compromised respiratory function — including difficulty coughing or ... increased risk of serious and possibly life-threatening complications ...
Breaking Medicine News(10 mins):Health News:A heart-felt need for dairy food 2Health News:CARRS-Q Host International Transport Safety Conference 2Health News:Canadian Hospital Database Now Offered by Definitive Healthcare 2Health News:MDA Offers Flu Shots to Those Affected by Muscle Disease 2
... The Food and Drug Administration (FDA) has awarded ... three-year, $1 million Orphan Products Development grant to ... the skin or internal organs., The unique, interdisciplinary, ... Beth Drolet, M.D., professor of dermatology and pediatrics, ...
... Governors Gene Therapeutics Research Institute at Cedars-Sinai Medical Center ... possible to sustain therapeutic gene expression in the central ... the presence of an anti-viral immune response mechanism that ... demonstrated in an animal model that the delivery system ...
... to be a multi-stage, multi-mechanism process by animal and ... Helicobacter pylori (H pylori) in the formation of gastric ... on November 7 in the World Journal of Gastroenterology ... H pylori on gastric cancer. , Gap junctions ...
... researchers say , THURSDAY, Oct. 25 (HealthDay News) -- ... can lessen cardiac injuries after heart attack and boost patient ... study in this week,s issue of The Lancet , ... muscle (infarct) and lessened what,s known as "reperfusion injuries," caused ...
... AMICAS, Inc (Nasdaq: AMCS ),announces the following Webcast: ... Webcast, When: November 1, 2007 @ 8:30 AM ET, ... the Internet -- Simply log on to the web at the ... Lisa Gould of AMICAS, Inc, 617-779-7892. If you are ...
... can search, sort, and compare more than 500 health ... plans on quality ... World Report and the,National Committee for Quality Assurance (NCQA) today ... ranking of U.S. health,maintenance organizations and point-of-service plans. Coinciding with ...
Cached Medicine News:Health News:Medical College of Wisconsin receives FDA grant 2Health News:Medical College of Wisconsin receives FDA grant 3Health News:Helicobacter pylori inhibits intercellular communication of cultured gastric cells 2Health News:U.S.News & World Report, NCQA Release Annual Rankings for 'America's Best Health Plans' 2Health News:U.S.News & World Report, NCQA Release Annual Rankings for 'America's Best Health Plans' 3
(Date:9/16/2014)... 16, 2014  Formex, LLC ("Formex"), a ... Mr. Greg Weilersbacher joined Formex as Director of ... Greg Weilersbacher has over ... expertise in Quality Assurance, Facility Validation, GMP ... brings to Formex a diverse wealth of ...
(Date:9/16/2014)... RICHMOND, Va. , Sept. 16, 2014 /PRNewswire-USNewswire/ ... (NAMCP) Medical Directors Institute has simultaneously released the ... the NAMCP Medical Diagnostics Dossier Template © , ... dossier template formats for either medical devices or ... unique aspects of each of these technology types ...
(Date:9/16/2014)... Northwest Biotherapeutics (NASDAQ: NWBO ) ... therapies for solid tumor cancers, announced today that its ... as a "Promising Innovative Medicine" (PIM) under the new ... UK in April 2014.  A PIM is the first ... under the EAMS.  The PIM designation ...
Breaking Medicine Technology:Greg Weilersbacher Joins Formex, LLC As Director of Quality Assurance and Quality Control 2NAMCP Medical Directors Institute releases NAMCP Medical Technologies and Diagnostics Dossier Templates to provide model approach for medical devices or diagnostics 2NW BIO'S CANCER VACCINE IS THE FIRST DRUG TO BE DESIGNATED BY UK AUTHORITIES AS A "PROMISING INNOVATIVE MEDICINE" (PIM) 2NW BIO'S CANCER VACCINE IS THE FIRST DRUG TO BE DESIGNATED BY UK AUTHORITIES AS A "PROMISING INNOVATIVE MEDICINE" (PIM) 3NW BIO'S CANCER VACCINE IS THE FIRST DRUG TO BE DESIGNATED BY UK AUTHORITIES AS A "PROMISING INNOVATIVE MEDICINE" (PIM) 4NW BIO'S CANCER VACCINE IS THE FIRST DRUG TO BE DESIGNATED BY UK AUTHORITIES AS A "PROMISING INNOVATIVE MEDICINE" (PIM) 5
... Sept. 20, 2011 TheraVasc ( www.theravasc.com ) announced the ... drug, TV1001, to diabetic patients. The trial included 12 diabetic ... oral formulations of TV1001, an enteric coated and a non-enteric ... drug.  Based on prior studies conducted in animals, the circulating ...
... American Medical Systems (AMS), a leading provider of world-class ... today announced the launch of a new consumer friendly website ... partners learn how penile prosthetic implants can restore sexual function ... the popularity of ED medications, these drugs fail to resolve ...
Cached Medicine Technology:TheraVasc Releases Phase I Trial Data Demonstrating Safety of Drug in Diabetic Patients 2New Website Provides Comprehensive Resource to Anyone With Erectile Dysfunction 2New Website Provides Comprehensive Resource to Anyone With Erectile Dysfunction 3
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
Medicine Products: