Navigation Links
Gene Therapy May Help Reverse Parkinson's Symptoms
Date:3/17/2011

fects on the participants, who ranged in age from 30 to 75, according to the study. The most common mild side-effects related to the treatment were headache (affecting seven of the patients in the infusion group versus two in the sham group) and nausea (six versus two).

Phase 3 trials must be conducted before the U.S. Food and Drug Administration decides whether to approve the treatment for general use.

The therapy, which was done with local anesthesia, used a harmless, inactive virus to deliver the GAD gene into each patient's subthalamic nucleus, a key brain region involving motor function. The gene instructs cells to begin making GABA neurotransmitters to re-establish the normal chemical balance that becomes dysfunctional as the disease progresses.

At the six-month mark, patients in the gene therapy group who had been off their medications for 12 hours showed an average 23.1 percent improvement on a scale used to assess motor function in Parkinson's patients, while placebo patients had a 12.7 percent improvement.

"For the first time, we're one step closer to a gene therapy for any neurological disease, because we passed this hurdle," said study co-author Dr. Michael Kaplitt, vice chairman for research in the department of neurological surgery at Weill Cornell Medical College in New York City.

"I think we're closer than we've ever been to be able to realistically tell patients . . . they can get this done," said Kaplitt, also a co-founder of Neurologix Inc., the Fort Lee, N.J. company that is developing the GAD therapy and that funded the current study. (Several other researchers also have financial ties to Neurologix and/or a patent related to the GAD product.)

Another surgical procedure, known as deep brain stimulation, which permanently implants a nerve control device in the brain, has helped control Parkinson's symptoms in thousands of patients over the last decade. Deep brain stimulation is apparently associated with
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. Nicotine replacement therapy is over-promoted since most ex-smokers quit unassisted
2. Social Anxiety and Panic - Alternative Treatment to Drugs and Therapy
3. Longview Therapy Center, PLLC, Unveils Its Definition Of Hope
4. Short-term radiation therapy successful on breast cancer
5. ASCROs Response to NY Times Articles on Radiation Therapy Incidents
6. Children With Cerebral Palsy Benefitting From New Physical Therapy Regimen
7. DavisPTnetwork Partners with the New York Physical Therapy Association to Provide Online Continuing Education
8. Behavioral therapy improves sleep and lives of patients with pain
9. WHI data confirm short-term heart disease risks of combination menopausal hormone therapy
10. Promising therapy for relapsing multibple sclerosis
11. Split-course palliative radiotherapy confirmed as effective treatment for advanced NSCLC
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Gene Therapy May Help Reverse Parkinson's Symptoms
(Date:9/30/2014)... HealthDay Reporter MONDAY, ... should be the first choice of birth control for ... Pediatrics state. Although most U.S. teens opt for ... contraception -- intrauterine devices (IUDs) and contraceptive implants -- ... And they should be the "first-line" choices for teenage ...
(Date:9/30/2014)... Houstonians seeking the latest information about ... on the Internet. Paul Vitenas, JR. M.D., F.A.C.S., ... surgeons, has launched a new website to better inform ... Botox Cosmetic services. The new website can be ... the new website, Botox Cosmetic is a non-surgical injectable ...
(Date:9/30/2014)... (PRWEB) September 30, 2014 ... caring individuals, National Children’s Oral Health Foundation: ... in grants to non-profit clinical partners. These ... Network and deliver comprehensive educational, preventive and ... Recipients include:,     Just Kids ...
(Date:9/30/2014)... TUESDAY, Sept. 30, 2014 (HealthDay News) -- For millions ... against excess weight and the threat of type 2 ... battle may be tougher for some than for others, ... promotes good health, it may not be as effective ... type 2 diabetes," said one expert, Dr. Ruth Loos, ...
(Date:9/30/2014)... 30, 2014 The global market for ... 38.75 billion by 2020 at an estimated CAGR of ... study by Grand View Research, Inc. Increasing prevalence of ... habits such as excessive alcohol consumption and growing geriatric ... is expected to serve this market as a high ...
Breaking Medicine News(10 mins):Health News:Pediatricians Endorse IUDs, Implants for Teen Birth Control 2Health News:Pediatricians Endorse IUDs, Implants for Teen Birth Control 3Health News:Dr. Paul Vitenas Launches New Website To Showcase The Benefits Of Botox Cosmetic 2Health News:Dr. Paul Vitenas Launches New Website To Showcase The Benefits Of Botox Cosmetic 3Health News:America's ToothFairy Awards More Than $150,000 in Grants to Save Young Smiles 2Health News:America's ToothFairy Awards More Than $150,000 in Grants to Save Young Smiles 3Health News:Can Exercise Prevent Type 2 Diabetes? Your Genes May Be Key 2Health News:Global Artificial Organ & Bionics Market Is Expecting Growth At CAGR Of 40.0% In Brain Bionics Segment From 2014 To 2020: Grand View Research, Inc. 2Health News:Global Artificial Organ & Bionics Market Is Expecting Growth At CAGR Of 40.0% In Brain Bionics Segment From 2014 To 2020: Grand View Research, Inc. 3Health News:Global Artificial Organ & Bionics Market Is Expecting Growth At CAGR Of 40.0% In Brain Bionics Segment From 2014 To 2020: Grand View Research, Inc. 4Health News:Global Artificial Organ & Bionics Market Is Expecting Growth At CAGR Of 40.0% In Brain Bionics Segment From 2014 To 2020: Grand View Research, Inc. 5Health News:Global Artificial Organ & Bionics Market Is Expecting Growth At CAGR Of 40.0% In Brain Bionics Segment From 2014 To 2020: Grand View Research, Inc. 6
... the largest,provider of business services to orthodontic and ... Texas and Atlanta, Georgia to,better serve the company,s ... offices confirm our operating principle that the,heart of ... but in the,hundreds of practices we serve each ...
... INDIANAPOLIS Public health officials are constantly in ... a possible pandemic, but to fight these deadly ... need it faster. , Researchers from the Regenstrief ... have found that automated electronic medical laboratory reporting ...
... TALLAHASSEE, Fla. -- About 5,000 people around the world die ... been developed to combat it in 40 years. Researchers at ... hope to change that through research made possible by a ... award will make it possible for Timothy A. Cross, the ...
... their relatives wish to donate organs when they die, because ... protecting the body of the deceased, according to research in ... University of Southampton, UK, spoke to 26 people who had ... organ donations about their views and experiences. The 23 relatives ...
... China, Jan. 17 /Xinhua-PRNewswire-FirstCall/ -- China Nepstar,Chain ... Nepstar" or "the Company"), the,largest drugstore chain ... join the,Shenzhen Charity Federation to launch a ... health issues among low-income working women,residents in ...
... industry,s voluntary withdrawal of oral ... and cold medicines in October 2007, WASHINGTON, Jan. ... (OTC) cough and cold medicines, the Consumer Healthcare,Products Association ... Administration (FDA) decision against the use of oral OTC ...
Cached Medicine News:Health News:OrthoSynetics(TM) Opens Regional Offices in Dallas, Atlanta 2Health News:Battling potential disease outbreaks online 2Health News:Researcher, magnet lab receive $2 million grant to target tuberculosis 2Health News:Relatives who decline organ donations face conflict and guilt 2Health News:Relatives who decline organ donations face conflict and guilt 3Health News:China Nepstar Chain Drugstore Launches Charitable Initiative to Promote Awareness of Low-income Working Women's Health Issues 2Health News:China Nepstar Chain Drugstore Launches Charitable Initiative to Promote Awareness of Low-income Working Women's Health Issues 3Health News:China Nepstar Chain Drugstore Launches Charitable Initiative to Promote Awareness of Low-income Working Women's Health Issues 4Health News:CHPA Lends Support to FDA's Announcement Against Use of Oral, Over-the-Counter Cough and Cold Medicines in Children Under Two 2
(Date:9/30/2014)... , Sept. 30, 2014 /PRNewswire/ ... CHDX ) today announced the completion of ... for $24.00 per share in cash.  Healthy Harmony is ... Ltd. ("Fosun") and Ms. Roberta Lipson , the ... merger agreement was adopted by Chindex,s stockholders at a ...
(Date:9/30/2014)... Calif. , Sept. 30, 2014  Allakos ... additional $10 million investment from current investors to ... additional financing was completed following achievement of a ... antibody program, and represents an extension of the ... in December 2012. With this additional financing, Allakos ...
(Date:9/29/2014)... SAN DIEGO , 29 septembre 2014 /PRNewswire/ ... Sankyo) (TSE : 4568) et Ambit Biosciences (NASDAQ : AMBI), ... de fusion définitif en vertu duquel Daiichi Sankyo ... en circulation d,Ambit Biosciences à 15 dollars par ... publique d,achat qui sera suivie d,une fusion avec ...
Breaking Medicine Technology:Chindex Completes Go-Private Transaction With Healthy Harmony Holdings, L.P. 2Chindex Completes Go-Private Transaction With Healthy Harmony Holdings, L.P. 3Chindex Completes Go-Private Transaction With Healthy Harmony Holdings, L.P. 4Chindex Completes Go-Private Transaction With Healthy Harmony Holdings, L.P. 5Allakos Inc. Raises Additional $10 Million to Expand its Portfolio and Fund Development of an Additional Antibody for Allergic and Inflammatory Diseases 2Allakos Inc. Raises Additional $10 Million to Expand its Portfolio and Fund Development of an Additional Antibody for Allergic and Inflammatory Diseases 3Allakos Inc. Raises Additional $10 Million to Expand its Portfolio and Fund Development of an Additional Antibody for Allergic and Inflammatory Diseases 4Daiichi Sankyo va acquérir Ambit Biosciences 2Daiichi Sankyo va acquérir Ambit Biosciences 3Daiichi Sankyo va acquérir Ambit Biosciences 4Daiichi Sankyo va acquérir Ambit Biosciences 5Daiichi Sankyo va acquérir Ambit Biosciences 6Daiichi Sankyo va acquérir Ambit Biosciences 7Daiichi Sankyo va acquérir Ambit Biosciences 8Daiichi Sankyo va acquérir Ambit Biosciences 9
... OMAHA, Neb., May 15 Creighton Medical Laboratories, based ... Omaha, announced today that it has become the first ... effective testing method for cancer. The method, called SNP ... laboratories to study cancer for several years. However, Creighton ...
... , in Damaged Tissue and Cells MANDEVILLE, La., ... leading expert in the field of non-surgical skin rejuvenation ... to speed up the healing process of damaged tissue ... a double-blinded, placebo-controlled clinical study of a glycerin-based bruise-reaction ...
Cached Medicine Technology:Creighton Medical Laboratories First to Offer New Cancer Test 2Creighton Medical Laboratories First to Offer New Cancer Test 3Glycerin Proven to Improve Bruising and Swelling Caused By Trauma to Skin 2
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: