Navigation Links
Gene Therapy May Ease Rheumatoid Arthritis
Date:2/6/2009

2 women who got injections report reduced pain and swelling

FRIDAY, Feb. 6 (HealthDay News) -- The first evidence that gene therapy can ease symptoms in people with rheumatoid arthritis (RA) has been reported by American and German researchers.

The study included two postmenopausal women with advanced RA. Researchers injected the interleukin-1 receptor antagonist (IL-1Ra) gene into the women's affected joints. IL-1Ra protein blocks the actions of interleukin-1 protein, which plays a role in the breakdown of cartilage that occurs in arthritis patients.

"The idea is that by remaining in place, the new gene can continuously block the action of the interleukin-1 within the joints. In essence, the gene becomes its own little factory, continuously working to alleviate pain and swelling," principal investigator Christopher Evans, director of the Center for Advanced Orthopaedic Studies at Beth Israel Deaconess Medical Center in Boston, said in a Harvard Medical School news release.

Four weeks after IL-1Ra was injected into their affected joints, both women reported reduced pain and swelling.

"In one of the two subjects, these effects were dramatic, and the gene-treated joints remained pain-free even though other joints experienced flares," said Evans, who is also a professor of orthopedic surgery at Harvard.

The findings were published in the February issue of the journal Human Gene Therapy. The study received funding from Orthogen, a German biotechnology company.

The study "helps extend gene therapy research to nongenetic, nonlethal diseases," said Evans, who added that arthritis "is a good target for this treatment, because the joint is a closed space into which we can inject genes."

More information

The Arthritis Foundation has more about rheumatoid arthritis.


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Vision restoration therapy shown to improve brain activity in brain injured patients
2. HIV therapy in pregnancy-data support WHO recommendations
3. Family-based treatment more effective than supportive psychotherapy in treating bulimia
4. Trial to Test Gene Therapy for Angina in Women
5. One of the Largest Post-WHI Physician Surveys Shows More Education is Needed: Patient Misinformation About Hormone Therapy Remains High
6. Aromatherapy Gift Line Sheds Humorous Light on Modern Therapy
7. Chemotherapy may be culprit for fatigue in breast cancer survivors
8. Atlanta Falcons Physical Therapy Centers Set to Launch This Fall
9. New Drug No Substitute for Standard Blood-Clot Therapy
10. Stem Cell Therapy Disappoints Against Rare Kidney Ailment
11. Nucletron Announces Management Buy-Out to More Effectively Meet the Demands of Its Customers and the Radiation Therapy Community
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Gene Therapy May Ease Rheumatoid Arthritis
(Date:8/20/2014)... 20, 2014 Get the report here: ... mergermarket presents “Deal Drivers 2014 Half Year Report for ... M&A activity in both North and South America, with ... About Merrill DataSite     , Merrill DataSite is a ... the due diligence process by providing a highly efficient ...
(Date:8/20/2014)... Angeles, CA (PRWEB) August 20, 2014 ... it is bringing on Wrench Advisors as a ... tasks including international large accounts. , As Wrench ... sales consultants can help your organization plan and ... executives and global distribution channels. Our experience developing ...
(Date:8/20/2014)... In its latest blog post, A Forever Recovery ... clients off to a great start and gives them a ... an important and possibly life-changing – perhaps even life-saving – ... understand the insidious nature of drug abuse: it doesn’t discriminate. ... targets a certain socioeconomic group, such as inner-city youth or ...
(Date:8/20/2014)... The award-winning plastic surgery group, The Aesthetic ... throughout Houston to a third office, located in Katy, ... building. ACPS plastic surgeon Dr. Rolando Morales said the ... has risen to become one of the largest, most ... since its establishment in 1996 by plastic surgeons Dr. ...
(Date:8/20/2014)... Antonio, TX (PRWEB) August 20, 2014 Texas ... their new study. The study will help test the effectiveness ... who suffer from high cholesterol may be eligible to participate ... too much cholesterol in the blood can lead to cardiovascular ... States. Lowering cholesterol can help reduce the risk of heart ...
Breaking Medicine News(10 mins):Health News:Register to Download Merrill DataSite's Report: Deal Drivers 2014 Half Year Report for the Americas 2Health News:Biocide Systems Announces Partnership with Wrench Advisors 2Health News:New A Forever Recovery Blog Post Reminds People that Drug Abuse Doesn’t Discriminate 2Health News:New A Forever Recovery Blog Post Reminds People that Drug Abuse Doesn’t Discriminate 3Health News:Aesthetic Center for Plastic Surgery Expands Its Reach in Texas 2Health News:Texas Medical Research Associates Announce New Study 2
... DNA vaccine trials conducted against the AIDS/HIV virus. The ... completed among 40 HIV- negative // volunteers. ... of vaccine biology. It involves direct injection of one ... human body. These vaccines precipitate an immune response so ...
... new generation stents that are deigned for slow release of ... stents according to a recent study conducted on stents used ... effectively prevent the overgrowth of scar tissue, thereby reducing incidence ... can either be inserted into a grafted vein or into ...
Fatehpur Sikri, Mughal Emperor Akbar's dream city, has come up some new finds, thanks to the labourious// excavatory work of the Archaeological Survey of India (ASI). ,According to Munazar Ali, a mo...
... from the University of Lund in Sweden have conducted ... of type 2 diabetes // . ,Exposure ... asthma, diabetes and many cancers. ,High levels of ... dichloro-diphenyl-trichloro-ethane or DDT in the blood of diabetic patients ...
... With the ever-increasing unsafe sex practices, massive migration and ... the incidence of the killer disease // amongst the ... ,Several districts of Orissa including Ganjam, Kendrapara, Balasore Nuapada, ... of HIV incidence, which poses a challenge to the ...
... warning German researchers say that loud noise can increase the ... risk is squarely attributed// to the noise related to the ... ,It was found that this noise had a ... the Institute for Social Medicine, Epidemiology and Health Economics at ...
Cached Medicine News:Health News:DNA Vaccine Trials Against HIV Virus In Sweden Nurture Hope 2Health News:Drug-Eluting Stents Ensure Patency Of The Saphenous Vein Grafts 2Health News:High Decibel Levels Raise Heart Disease Risk 2
(Date:8/20/2014)... Aug. 20, 2014 Reportlinker.com announces that ... its catalogue: Global Coatings for Medical ... This report analyzes the worldwide ... Million by the following Product Segments: Active Coatings, ... report provides separate comprehensive analytics for the US, ...
(Date:8/20/2014)... 20, 2014 ApolloDx™ today announced it will ... a special event at the company,s office in ... 5, 2014. The event, which will start at 10:00 ... www.apollodx.com .    "We believe our ... Jared Bauer , Co-Founder and Managing Partner of ApolloDx. ...
(Date:8/20/2014)... Aug. 20, 2014   Easy Breathe , the fastest growing ... " Easy Blog " - has received more than 4.5 million ... "We are thrilled that so many people are finding our ... of Easy Breathe. "We,re committed to making sleep apnea more widely ... stay informed about sleep apnea news , troubleshooting advice ...
Breaking Medicine Technology:Global Coatings for Medical Devices Industry 2Global Coatings for Medical Devices Industry 3Global Coatings for Medical Devices Industry 4Global Coatings for Medical Devices Industry 5Global Coatings for Medical Devices Industry 6Global Coatings for Medical Devices Industry 7Global Coatings for Medical Devices Industry 8Global Coatings for Medical Devices Industry 9Global Coatings for Medical Devices Industry 10Global Coatings for Medical Devices Industry 11Global Coatings for Medical Devices Industry 12Global Coatings for Medical Devices Industry 13Global Coatings for Medical Devices Industry 14Global Coatings for Medical Devices Industry 15Global Coatings for Medical Devices Industry 16Global Coatings for Medical Devices Industry 17Global Coatings for Medical Devices Industry 18Global Coatings for Medical Devices Industry 19Global Coatings for Medical Devices Industry 20Global Coatings for Medical Devices Industry 21Easy Breathe Blog Emerges as the Go-To Resource for Sleep Apnea Sufferers 2Easy Breathe Blog Emerges as the Go-To Resource for Sleep Apnea Sufferers 3Easy Breathe Blog Emerges as the Go-To Resource for Sleep Apnea Sufferers 4