Navigation Links
Gene Therapy Improves Diabetic Neuropathy in Study
Date:4/29/2009

Injections appear to be safe, but more research needed

WEDNESDAY, April 29 (HealthDay News) -- Gene therapy shows promise in treating diabetic polyneuropathy, a disorder that commonly affects diabetics who've had the disease for many years, a new study finds.

Researchers in Boston found that intramuscular injections of vascular endothelial growth factor (VEGF) gene may help patients with diabetic polyneuropathy. The study included 39 patients who received three sets of injections of VEGF gene in one leg and 11 patients who received a placebo.

Six months after treatment, the patients who received the VEGF gene injections showed greater improvements in sensory symptoms and pain than those who received the placebo.

Loss of sensation and pain in the legs and feet, weakness, and balance problems are among the symptoms associated with diabetic neuropathy. The loss of sensation means that ulcerations on the feet may go undetected, which can lead to amputation.

"Most patients had fairly severe neuropathy, and the expectation for improvement was therefore not high," Dr. Allan Ropper, executive vice chair of the neurology department at Brigham and Women's Hospital in Boston, said in a hospital news release.

The VEGF gene used in the study is active without packaging it in a virus, which is a major safety advantage, according to the researchers.

"The study shows that this form of gene transfer therapy can be performed relatively safely, but further investigation using a larger study group is needed before it can be introduced as a mainstream therapy," Ropper said.

The study was presented in Seattle at the annual meeting of the American Academy of Neurology.

More information

The U.S. National Institute of Diabetes and Digestive and Kidney Diseases has more about diabetes-related nerve damage.



-- Robert Preidt



SOURCE: Brigham and Women's Hospital, news release, April 28, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Vision restoration therapy shown to improve brain activity in brain injured patients
2. HIV therapy in pregnancy-data support WHO recommendations
3. Family-based treatment more effective than supportive psychotherapy in treating bulimia
4. Trial to Test Gene Therapy for Angina in Women
5. One of the Largest Post-WHI Physician Surveys Shows More Education is Needed: Patient Misinformation About Hormone Therapy Remains High
6. Aromatherapy Gift Line Sheds Humorous Light on Modern Therapy
7. Chemotherapy may be culprit for fatigue in breast cancer survivors
8. Atlanta Falcons Physical Therapy Centers Set to Launch This Fall
9. New Drug No Substitute for Standard Blood-Clot Therapy
10. Stem Cell Therapy Disappoints Against Rare Kidney Ailment
11. Nucletron Announces Management Buy-Out to More Effectively Meet the Demands of Its Customers and the Radiation Therapy Community
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Gene Therapy Improves Diabetic Neuropathy in Study
(Date:12/2/2016)... ... December 02, 2016 , ... The PAINWeekEnd Regional Conference ... and Spa in Honolulu, offering local frontline clinicians the opportunity to extend their ... The demand for supplemental training related to pain management has surged dramatically in ...
(Date:12/2/2016)... (PRWEB) , ... December 02, 2016 , ... Sourced from ... has some unique properties including its unmatched natural purity of just 6 ppm TDS ... and crisp. , Nothing Water has been available in several ShopRite and FoodTown stores ...
(Date:12/2/2016)... ... December 02, 2016 , ... Yisrayl Hawkins, at The ... how this current generation fits into Bible Prophecy. Yisrayl says this generation, known as ... to this conclusion, showing how the details line up exactly with Bible Prophecy – ...
(Date:12/2/2016)... CA (PRWEB) , ... December 02, 2016 , ... ... care journeys, announced today that it has raised $6.0 million in an initial ... by Clarify Health’s conviction that patients and their caregivers can receive far better ...
(Date:12/2/2016)... ... December 02, 2016 , ... ... to build intelligent, connected applications, was named the best Sales Team of 2016 ... winner announcement was made today by the Software & Information Industry Association (SIIA), ...
Breaking Medicine News(10 mins):
(Date:12/2/2016)... -- Allergan plc (NYSE: AGN ), a leading ... announced Accelerated Share Repurchase (ASR) Program. Logo - ... , ... announced, the Company entered into a variable tenor ASR arrangement ... $10 billion of its ordinary shares. Approximately 40.5 million shares ...
(Date:11/30/2016)... , Nov 30, 2016 ... "US Market Overview for Neuromodulation, Neurovascular, Neurosurgical and Monitoring Devices ... ... The full report suite on the ... fluid external drainage systems, intracranial pressure monitoring devices, detachable coils, ...
(Date:11/30/2016)... Nov. 30, 2016 Varian Medical Systems (NYSE: ... America,s Most JUST Company in the Healthcare Equipment and ... magazine,s inaugural "JUST 100 List." The rankings are ... surveys ever conducted on attitudes towards corporate behavior, involving ... list ranks U.S companies against their peers within 32 ...
Breaking Medicine Technology: