Navigation Links
Gene Test May ID Younger Women at Risk for Melanoma

Variation found in more than 40% of females under 50 raises odds almost 4-fold

WEDNESDAY, March 25 (HealthDay News) -- A genetic variation that's associated with a nearly fourfold increased risk of melanoma in women under the age of 50 has been identified by researchers at the New York University School of Medicine.

Identification of this variation in a gene called MDM2 could lead to a screening test to identify women at high risk for the deadly skin cancer.

If confirmed in further studies, the increased risk caused by the MDM2 variation "is higher than a lot of the other clinical factors that we know, such as blistering sunburns, freckling, and family history," study author Dr. David Polsky, an associate professor of dermatology and director of the Pigmented Lesion Section of the dermatology department at NYU School of Medicine, said in a university news release.

"Potentially, we have a genetic test that might identify premenopausal women who are at higher risk for melanoma. And if that's not the case, then we might want to have increased surveillance of those patients including more frequent visits to the doctor, more rigorous teaching of skin self-examination, and other preventive steps," he said.

In their study of 227 melanoma patients, Polsky and colleagues found that more than 40 percent of female patients younger than 50 had the MDM2 genetic variation, compared with about 16 percent of female patients older than 50. The difference in frequency of the genetic variation corresponded to a 3.89-fold increased risk of melanoma among women younger than 50, the researchers said.

The study was published online March 24 and was expected to be in the April 1 print issue of the journal Clinical Cancer Research.

More information

The U.S. National Cancer Institute has more about melanoma.

-- Robert Preidt

SOURCE: New York University Langone Medical Center, news release, March 24, 2009

Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. NYU study finds new risk factor for melanoma in younger women
2. Band Aid Mini Facelift Developed by Atlanta Plastic Surgeon John L. LeRoy, MD can Help Patients Look Younger for Less Money
3. Younger Women With Breast Cancer Face Added Peril
4. Older Adults Get Drunk Faster Than Younger Drinkers
5. Younger breast cancer patients have greater chance of recurrence
6. Silent Strokes More Common in Younger People Than Thought
7. ER Less Likely to Diagnose Stroke in Younger Folks
8. Study shows younger women with endometrial cancer can safely keep ovaries, avoid early menopause
9. Looking Years Younger, Raising a Few Brows
10. Half of Adults 50 and Younger With Low 10-Year Risk of CVD Have High Lifetime Risk
11. Panic attacks linked to higher risk of heart attacks and heart disease, especially in younger people
Post Your Comments:
Related Image:
Gene Test May ID Younger Women at Risk for Melanoma
(Date:11/29/2015)... Aliso Viejo, CA (PRWEB) , ... November 29, ... ... is an all new and unique analog distortion effect tool designed specially for ... to their footage, and create limiltess looks with the easy-to-use modification controls. Destoying ...
(Date:11/28/2015)... ... November 28, 2015 , ... Safe storage for contraceptive devices ... inventors, one from Lakewood, New Jersey and the other from Bradley Beach, New Jersey, ... to save the expense of having to replace NuvaRings more often than necessary. As ...
(Date:11/27/2015)... , ... November 28, 2015 , ... There is only ... outperform our billings from last year? , This question has not been an easy ... coming to the retirement age and the younger workforce don’t share the same discipline ...
(Date:11/27/2015)... ... , ... The rapid speed at which Americans are aging ... is needed, especially with Alzheimer’s, dementia and other cognitive conditions becoming more prevalent. ... part of this equation: 80 percent of medical care occurs in the home, ...
(Date:11/27/2015)... CA (PRWEB) , ... November 27, 2015 , ... Lizzie’s ... , The company is offering customers 10% off of their purchase of lice treatment ... treatment at full price. According to a company spokesperson. “Finding lice is a sure ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... -- Research and Markets ( ) has announced ... by Type (Dressings, Therapy Devices, Active Wound Care), Application ... and Geography - Global Forecast to 2020" report ... --> The purpose of this report is ... global advanced wound care market. It involves deep dive ...
(Date:11/26/2015)... November 26, 2015 ... adds "Global Repaglinide Industry ... Report on China Repaglinide Market, 2010-2019" ... data and information to its online ... . --> ...
(Date:11/26/2015)... Research and Markets ( ) ... Future Horizons and Growth Strategies in the Italian ... Segment Forecasts, Competitive Intelligence, Emerging Opportunities" report ... --> This new 247-page report ... drug monitoring market, including emerging tests, technologies, instrumentation, ...
Breaking Medicine Technology: