Navigation Links
Gene Test May ID Younger Women at Risk for Melanoma
Date:3/25/2009

Variation found in more than 40% of females under 50 raises odds almost 4-fold

WEDNESDAY, March 25 (HealthDay News) -- A genetic variation that's associated with a nearly fourfold increased risk of melanoma in women under the age of 50 has been identified by researchers at the New York University School of Medicine.

Identification of this variation in a gene called MDM2 could lead to a screening test to identify women at high risk for the deadly skin cancer.

If confirmed in further studies, the increased risk caused by the MDM2 variation "is higher than a lot of the other clinical factors that we know, such as blistering sunburns, freckling, and family history," study author Dr. David Polsky, an associate professor of dermatology and director of the Pigmented Lesion Section of the dermatology department at NYU School of Medicine, said in a university news release.

"Potentially, we have a genetic test that might identify premenopausal women who are at higher risk for melanoma. And if that's not the case, then we might want to have increased surveillance of those patients including more frequent visits to the doctor, more rigorous teaching of skin self-examination, and other preventive steps," he said.

In their study of 227 melanoma patients, Polsky and colleagues found that more than 40 percent of female patients younger than 50 had the MDM2 genetic variation, compared with about 16 percent of female patients older than 50. The difference in frequency of the genetic variation corresponded to a 3.89-fold increased risk of melanoma among women younger than 50, the researchers said.

The study was published online March 24 and was expected to be in the April 1 print issue of the journal Clinical Cancer Research.

More information

The U.S. National Cancer Institute has more about melanoma.



-- Robert Preidt



SOURCE: New York University Langone Medical Center, news release, March 24, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. NYU study finds new risk factor for melanoma in younger women
2. Band Aid Mini Facelift Developed by Atlanta Plastic Surgeon John L. LeRoy, MD can Help Patients Look Younger for Less Money
3. Younger Women With Breast Cancer Face Added Peril
4. Older Adults Get Drunk Faster Than Younger Drinkers
5. Younger breast cancer patients have greater chance of recurrence
6. Silent Strokes More Common in Younger People Than Thought
7. ER Less Likely to Diagnose Stroke in Younger Folks
8. Study shows younger women with endometrial cancer can safely keep ovaries, avoid early menopause
9. Looking Years Younger, Raising a Few Brows
10. Half of Adults 50 and Younger With Low 10-Year Risk of CVD Have High Lifetime Risk
11. Panic attacks linked to higher risk of heart attacks and heart disease, especially in younger people
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Gene Test May ID Younger Women at Risk for Melanoma
(Date:6/26/2016)... ... ... Kasmer, a legally blind and certified personal trainer is helping to develop a weight loss ... plans to fix the two major problems leading the fitness industry today:, ... , They don’t eliminate all the reasons people quit their exercise program ...
(Date:6/25/2016)... ... , ... "With 30 hand-drawn hand gesture animations, FCPX users can easily customize ... Pixel Film Studios. , ProHand Cartoon’s package transforms over 1,300 hand-drawn pictures into ... Simply select a ProHand generator and drag it above media or text in the ...
(Date:6/25/2016)... ... June 25, 2016 , ... Conventional wisdom preaches the benefits of moderation, whether ... latter, setting the bar too high can result in disappointment, perhaps even self-loathing. However, ... their goal. , Research from PsychTests.com reveals that behind the tendency ...
(Date:6/24/2016)... Texas (PRWEB) , ... June 24, 2016 , ... ... International Conference and Scientific Sessions in Dallas that it will receive two significant ... of the grants came as PHA marked its 25th anniversary by recognizing patients, ...
(Date:6/24/2016)... Plano, TX (PRWEB) , ... June 24, 2016 , ... ... taking part in Genome magazine’s Code Talker Award, an essay contest in which patients ... for an award to be presented at the 2016 National Society of Genetic Counselors ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , June 24, 2016  Global Blood Therapeutics, ... company developing novel therapeutics for the treatment of ... announced the closing of its previously announced underwritten ... at the public offering price of $18.75 per ... were offered by GBT. GBT estimates net proceeds ...
(Date:6/24/2016)... Va. , June 24, 2016 The ... set of recommendations that would allow biopharmaceutical ... (HCEI) with entities that make formulary and coverage decisions, ... the "value" of new medicines. The recommendations ... does not appear on the drug label, a prohibition ...
(Date:6/24/2016)... According to a new market ... Needles, Safety Pen Needles), Needle Length (4mm, 5mm, 6mm, ... of Purchase (Retail, Non-Retail) - Trends & Global Forecasts ... market for the forecast period of 2016 to 2021. ... by 2021 from USD 1.65 Billion in 2016, growing ...
Breaking Medicine Technology: