Navigation Links
Gene Study Yields New Clues to Crohn's Disease, Colitis
Date:10/31/2012

WEDNESDAY, Oct. 31 (HealthDay News) -- Scientists say research into the genetics of inflammatory bowel disease -- which includes Crohn's disease and ulcerative colitis -- is revealing new insights into the origin of this set of illnesses.

The researchers said they have linked genetic variations in 163 regions of the human genome with a heightened risk of developing inflammatory bowel disease (IBD). Of those regions, 71 are newly discovered.

IBD comprises a group of chronic, autoimmune digestive disorders that affect 2.5 million people worldwide. Symptoms include abdominal pain and diarrhea and patients typically require lifelong treatment with drug therapy. Many also require surgery to repair tissue damage caused by the disease.

In this study, researchers analyzed data from about 34,000 people who took part in 15 previous studies of either Crohn's disease or ulcerative colitis. They also examined data from genome-wide scans of more than 41,000 DNA samples from Crohn's disease and ulcerative colitis patients collected at 11 centers around the world.

In addition to confirming that 92 regions of the human genome identified in previous studies are associated with a significant risk for the two illnesses, the new study linked 71 new regions to IBD.

The regions pinpointed in this study overlap those linked with other autoimmune diseases and suggest that IBD results from overactive immune defense systems that evolved to combat serious bacterial infections, the researchers said.

The findings appear in the Nov. 1 issue of the journal Nature.

"Until this point we have been studying the two main forms of IBD -- Crohn's disease and ulcerative colitis -- separately," co-lead author Judy Cho, professor of gastroenterology and genetics at Yale School of Medicine, said in a Yale news release. "We created this study based on what seems to be a vast amount of genetic overlap between the two disorders."

'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Health inequalities could be reduced by more effective health care, says new study
2. Automated calls help patients in under-developed countries manage blood pressure, U-M study finds
3. Health inequalities could be reduced by more effective healthcare, says new study
4. Study suggests too much risk associated with SSRI usage and pregnancy
5. Flirting Works as Negotiation Tactic for Women: Study
6. Study suggests new way to prevent recurrent ear infections
7. Using Canadas Health System as Model Might Cut U.S. Costs: Study
8. The Biggest Loser May Sour Viewers on Exercise, Study Finds
9. Fast-Food Breakfast Sandwiches May Slow Down Blood Flow: Study
10. Breast Cancer Survival Varies by Race, Ethnicity, Study Shows
11. Autism Tough to Spot Before 6 Months of Age, Study Suggests
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Gene Study Yields New Clues to Crohn's Disease, Colitis
(Date:7/14/2014)... to a new market research report "Power Electronics Market ... (Power IC, Power Module & Power Discrete), Applications, and ... the Power Electronics market is expected to boom in ... at $36.86 Billion and expected to grow at a ... includes an in-depth analysis of the applications and geography. ...
(Date:7/14/2014)... July 14, 2014 This report ... market in Americas. The analysis includes market size ... period and key company share data by revenue ... Brazil and Mexico. It uses data and information ... and in-house analysis. , Scope, ...
(Date:7/14/2014)... (HealthDay News) -- Along with improving vision, cataract surgery ... and other types of dementia, a new study suggests. ... the researchers said. "These preliminary results indicate that ... people with dementia and their loved ones, both visual ... Reserve University and University Hospitals Case Medical Center, in ...
(Date:7/14/2014)... By Kathleen Doheny ... -- Losing a spouse may be linked to multiple health ... new study. For certain seniors, widowhood may even delay ... mild memory problem, losing the spouse was associated with a ... stayed married," said study researcher Dr. Bryan Woodruff. ...
(Date:7/14/2014)... T.E.N., an information technology and security ... nominations will be accepted now through Sept. 12, ... North America Awards. , Awards include the ... executives who have made a positive impact on ... compliance, privacy and information security; and the ISE® ...
Breaking Medicine News(10 mins):Health News:Power Electronics Market Estimated to Reach $36.86 Billion by 2020 at CAGR of 7.74% - New Report by MarketsandMarkets 2Health News:Power Electronics Market Estimated to Reach $36.86 Billion by 2020 at CAGR of 7.74% - New Report by MarketsandMarkets 3Health News:Power Electronics Market Estimated to Reach $36.86 Billion by 2020 at CAGR of 7.74% - New Report by MarketsandMarkets 4Health News:Power Electronics Market Estimated to Reach $36.86 Billion by 2020 at CAGR of 7.74% - New Report by MarketsandMarkets 5Health News:Americas Transcatheter Heart Valves Market 2020 Forecasts in New Research Report at LifeScienceIndustryResearch.com 2Health News:Americas Transcatheter Heart Valves Market 2020 Forecasts in New Research Report at LifeScienceIndustryResearch.com 3Health News:Americas Transcatheter Heart Valves Market 2020 Forecasts in New Research Report at LifeScienceIndustryResearch.com 4Health News:Cataract Surgery a Plus for Someone With Dementia, Study Says 2Health News:Widowhood May Delay Dementia in Some Seniors, Study Finds 2Health News:Widowhood May Delay Dementia in Some Seniors, Study Finds 3Health News:T.E.N. Accepting Nominations for the 2014 Information Security Executive® North America Awards 2Health News:T.E.N. Accepting Nominations for the 2014 Information Security Executive® North America Awards 3
... cholesterol level in blood.,High level of cholesterol, which is ... can lead to serious health risks. ,// ,Researchers ... examined 199 healthy middle-aged men and women to know ... can increase cholesterol and heighten cardiovascular risk, reports Newswise ...
... of bird flu, even as the government has given approval ... ,The latest outbreaks of the deadly H5N1 strain of ... southwestern province of Yunnan and the northwestern region of Ningxia, ... birds died in Yunnan's Chuxiong district Thursday, and 230 died ...
... is planning expansion of its super-speciality hospital chain with ... Kolkata and Bangalore.// ,"We have embarked on the ... Delhi) which would be ready by 2007-end. We also ... the chain's vice president, told IANS., ,Unlike the ...
... more than 1,200 children, whose organs were removed after death ... average of about ?2,900 in a compensation deal announced recently ... the apex body had fought the cases involving organ-retention ... to a total figure of around ?3.6 million for the ...
... people could be putting their health at risk by ... and other health professionals.// ,The survey of more ... Health Professions Council (HPC), found that about 81% of ... professional were oblivious to whether they were properly qualified ...
... juice has anti-bacterial properties? It has now been found ... compounds that can help preserve dental health by prevention ... University of Rochester Medical Center have been credited with ... acts just similar to a Teflon sheath, commonly used ...
Cached Medicine News:Health News:Wockhardt Group Plans Hospital In Delhi By End-2007 2Health News:Organ Scandals Compensation And The Aftermath 2Health News:Credentials Of Specialists Need To Be Checked 2Health News:Cranberry juice to Prevent Dental Decay 2
(Date:7/14/2014)... ANAHEIM, Calif. , July 14, 2014  Mallinckrodt ... (NASDAQ: QCOR ) today announced that the registration ... Exchange Commission ("SEC") by Mallinckrodt plc on May 16, 2014 ... proxy statement of Mallinckrodt and Questcor that also constitutes a ... The registration statement on Form S-4 is available on the ...
(Date:7/14/2014)... BEIJING , July 14, 2014 Sinovac Biotech Ltd. (NASDAQ: ... China , announced today that it will hold its 2014 ... Beijing Time. The meeting will be held at No. 39 Shangdi Xi ... record as of July 9, 2014 will be eligible to vote and ... is to approve the re-election of Weidong Yin , Yuk ...
(Date:7/14/2014)... and LONDON , July 14, 2014 ... IXICO plc (AIM: IXI) jointly announced today the formation ... companies. Dr. Edward Ashton , Ph.D., chief scientific ... have seven members. "The formation of this ... the international commercial and operational alliance we signed with ...
Breaking Medicine Technology:Mallinckrodt Pharmaceuticals And Questcor Pharmaceuticals Provide Update On Transaction 2Mallinckrodt Pharmaceuticals And Questcor Pharmaceuticals Provide Update On Transaction 3Mallinckrodt Pharmaceuticals And Questcor Pharmaceuticals Provide Update On Transaction 4Mallinckrodt Pharmaceuticals And Questcor Pharmaceuticals Provide Update On Transaction 5Mallinckrodt Pharmaceuticals And Questcor Pharmaceuticals Provide Update On Transaction 6Mallinckrodt Pharmaceuticals And Questcor Pharmaceuticals Provide Update On Transaction 7Sinovac Schedules 2014 Annual Meeting of Shareholders 2Sinovac Schedules 2014 Annual Meeting of Shareholders 3VirtualScopics, Inc. And IXICO plc Announce The Formation Of A Scientific Advisory Board To Benefit Both Companies; Dr. Edward Ashton, Ph.D. Appointed Chairman 2VirtualScopics, Inc. And IXICO plc Announce The Formation Of A Scientific Advisory Board To Benefit Both Companies; Dr. Edward Ashton, Ph.D. Appointed Chairman 3VirtualScopics, Inc. And IXICO plc Announce The Formation Of A Scientific Advisory Board To Benefit Both Companies; Dr. Edward Ashton, Ph.D. Appointed Chairman 4VirtualScopics, Inc. And IXICO plc Announce The Formation Of A Scientific Advisory Board To Benefit Both Companies; Dr. Edward Ashton, Ph.D. Appointed Chairman 5VirtualScopics, Inc. And IXICO plc Announce The Formation Of A Scientific Advisory Board To Benefit Both Companies; Dr. Edward Ashton, Ph.D. Appointed Chairman 6VirtualScopics, Inc. And IXICO plc Announce The Formation Of A Scientific Advisory Board To Benefit Both Companies; Dr. Edward Ashton, Ph.D. Appointed Chairman 7VirtualScopics, Inc. And IXICO plc Announce The Formation Of A Scientific Advisory Board To Benefit Both Companies; Dr. Edward Ashton, Ph.D. Appointed Chairman 8VirtualScopics, Inc. And IXICO plc Announce The Formation Of A Scientific Advisory Board To Benefit Both Companies; Dr. Edward Ashton, Ph.D. Appointed Chairman 9
... by genomics, SAN DIEGO, April 14 ... Therapeutics, Inc. (CTI) (Nasdaq,and MTAX: CTIC), presented data ... patients more likely to respond to treatment with ... for,Cancer Research (AACR) annual meeting. These findings will ...
... April 13 Researchers from the,Barbara Ann ... findings,showing that adding curcumin or resveratrol to ... growth of chemo-resistant colon cancer,cells. The poster ... Cancer Research (AACR) Annual Meeting in San ...
Cached Medicine Technology:New Gene Discovery Suggests Which Patients CTI's Brostallicin May Benefit 2New Gene Discovery Suggests Which Patients CTI's Brostallicin May Benefit 3New Gene Discovery Suggests Which Patients CTI's Brostallicin May Benefit 4New Gene Discovery Suggests Which Patients CTI's Brostallicin May Benefit 5Karmanos Researchers Find Non-Toxic Agents Added to Conventional Chemotherapy Decrease Survival of Colon Cancer Cells 2
... an 125I radioimmunoassay designed for,in ... quantitative,measurement of estradiol in serum, ... in girls,and gynecomastia in men, ... amenorrhea. It is,also intended for ...
... determination of Estradiol (E2) concentration in human serum ... hormone with a phenolic A ring. This ... It is the most potent natural Estrogen, ... smaller amounts by the adrenal cortex, and the ...
... is the most potent, naturally secreted estrogen ... the ovary [1]. In the ovary, estradiol ... estrone, a less potent estrogen derived from ... many body tissues. In men, small amounts ...
... VITROS ECi brings true automation and ... testing. Highly sensitive assays for thyroid, ... bone metabolism testing are currently available, ... The VITROS ECi can simultaneously process ...
Medicine Products: